Project measure / variable:   Poon1   RMS_M18

ID, description, units MPD:47503   RMS_M18   BrdU+ cells of rostral migratory stream   [n/mm]  at age 18mo  
Data set, strains Poon1   inbred   9 strains     sex: both     age: 78wks
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  STRAIN COMPARISON PLOT
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Poon1 - BrdU+ cells of rostral migratory stream at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains6 strains
Mean of the strain means23.1   n/mm 21.1   n/mm
Median of the strain means22.0   n/mm 19.2   n/mm
SD of the strain means± 7.26 ± 6.38
Coefficient of variation (CV)0.315 0.303
Min–max range of strain means15.2   –   34.4   n/mm 15.0   –   32.2   n/mm
Mean sample size per strain2.6   mice 2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 77.4668 77.4668 0.8296 0.3759
strain 4 727.8902 181.9726 1.9487 0.1513
sex:strain 4 361.543 90.3857 0.9679 0.4519
Residuals 16 1494.0736 93.3796


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.2 15.6   2   11.0 0.67 12.2, 34.2 0.02
129S1/SvImJ m 32.2 16.4   2   11.6 0.509 20.6, 43.8 1.74
129X1/SvJ f 34.4 15.1   3 8.7 0.438 18.0, 47.7 1.56
129X1/SvJ m 24.6 1.39   2   0.985 0.0567 23.6, 25.5 0.55
A/J f 31.8 11.9   2   8.44 0.375 23.4, 40.2 1.2
A/J m 19.8 7.66   4 3.83 0.387 13.2, 27.8 -0.2
BALB/cByJ f 17.2 14.2   3 8.21 0.829 5.76, 33.1 -0.81
C3H/HeJ f 22.0 4.07   3 2.35 0.185 17.6, 25.7 -0.15
C57BL/6J f 16.5 0.0   1   0.0 0.0 16.5, 16.5 -0.91
C57BL/6J m 15.0 4.28   3 2.47 0.285 10.3, 18.7 -0.95
CBA/J f 17.6 3.94   3 2.28 0.224 13.0, 20.2 -0.76
CBA/J m 16.3 2.89   3 1.67 0.178 13.2, 19.0 -0.75
DBA/2J f 15.2 1.77   2   1.25 0.117 13.9, 16.4 -1.09
DBA/2J m 18.6 8.85   3 5.11 0.477 10.3, 27.9 -0.39
FVB/NJ f 29.9 6.31   3 3.64 0.211 23.1, 35.6 0.94


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.215 6.833 37.7003 8.7297
129S1/SvImJ m 32.235 6.833 46.7203 17.7497
129X1/SvJ f 34.41 5.5791 46.2372 22.5828
129X1/SvJ m 24.555 6.833 39.0403 10.0697
A/J f 31.79 6.833 46.2753 17.3047
A/J m 19.785 4.8317 30.0277 9.5423
CBA/J f 17.56 5.5791 29.3872 5.7328
CBA/J m 16.2567 5.5791 28.0839 4.4295
DBA/2J f 15.195 6.833 29.6803 0.7097
DBA/2J m 18.5767 5.5791 30.4039 6.7495


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 27.725 4.8317 37.9677 17.4823
129X1/SvJ both 29.4825 4.4107 38.8327 20.1323
A/J both 25.7875 4.1843 34.6579 16.9171
CBA/J both 16.9083 3.945 25.2714 8.5452
DBA/2J both 16.8858 4.4107 26.2361 7.5356




  GWAS USING LINEAR MIXED MODELS