Project measure / variable:   Poon1   RMS_M12

ID, description, units MPD:47502   RMS_M12   BrdU+ cells of rostral migratory stream   [n/mm]  at age 12mo  
Data set, strains Poon1   inbred   9 strains     sex: both     age: 52wks
Procedure histopathology
Ontology mappings

  STRAIN COMPARISON PLOT
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Poon1 - BrdU+ cells of rostral migratory stream at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means37.4   n/mm 34.4   n/mm
Median of the strain means35.6   n/mm 32.1   n/mm
SD of the strain means± 7.50 ± 8.88
Coefficient of variation (CV)0.201 0.258
Min–max range of strain means25.6   –   48.0   n/mm 21.6   –   46.1   n/mm
Mean sample size per strain2.9   mice 2.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 140.0049 140.0049 1.5369 0.225
strain 7 2494.3613 356.3373 3.9116 0.0041
sex:strain 7 308.7756 44.1108 0.4842 0.8381
Residuals 29 2641.8108 91.0969


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 42.9 15.0   3 8.68 0.35 29.8, 59.3 0.74
129S1/SvImJ m 42.8 13.2   3 7.65 0.31 29.2, 55.6 0.94
129X1/SvJ f 33.0 6.12   2   4.32 0.185 28.7, 37.4 -0.58
129X1/SvJ m 21.6 9.43   3 5.45 0.437 12.0, 30.9 -1.45
A/J f 48.0 2.51   3 1.45 0.0522 46.3, 50.9 1.42
A/J m 41.7 2.45   3 1.42 0.0588 39.7, 44.5 0.82
BALB/cByJ f 35.8 15.8   3 9.1 0.441 19.6, 51.1 -0.21
BALB/cByJ m 30.0 3.65   3 2.11 0.122 26.2, 33.4 -0.5
C3H/HeJ f 34.9 2.56   3 1.48 0.0732 32.0, 36.8 -0.33
C3H/HeJ m 23.2 0.0   1   0.0 0.0 23.2, 23.2 -1.27
C57BL/6J f 32.5 2.27   3 1.31 0.0699 31.2, 35.2 -0.65
C57BL/6J m 31.3 6.23   3 3.6 0.199 27.4, 38.5 -0.35
CBA/J f 25.6 3.34   3 1.93 0.131 21.8, 28.0 -1.57
CBA/J m 32.1 4.54   2   3.21 0.141 28.9, 35.3 -0.26
DBA/2J f 35.6 7.33   2   5.18 0.206 30.4, 40.8 -0.24
DBA/2J m 41.2 15.2   2   10.7 0.369 30.5, 52.0 0.76
FVB/NJ f 48.0 11.9   5 5.33 0.248 35.9, 67.0 1.42
FVB/NJ m 46.1 9.6   2   6.79 0.208 39.3, 52.9 1.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 42.92 5.5105 54.1902 31.6498
129S1/SvImJ m 42.77 5.5105 54.0402 31.4998
129X1/SvJ f 33.045 6.749 46.8482 19.2418
129X1/SvJ m 21.5933 5.5105 32.8636 10.3231
A/J f 48.05 5.5105 59.3202 36.7798
A/J m 41.74 5.5105 53.0102 30.4698
BALB/cByJ f 35.7667 5.5105 47.0369 24.4964
BALB/cByJ m 29.9767 5.5105 41.2469 18.7064
C57BL/6J f 32.5333 5.5105 43.8036 21.2631
C57BL/6J m 31.28 5.5105 42.5502 20.0098
CBA/J f 25.5533 5.5105 36.8236 14.2831
CBA/J m 32.11 6.749 45.9132 18.3068
DBA/2J f 35.575 6.749 49.3782 21.7718
DBA/2J m 41.225 6.749 55.0282 27.4218
FVB/NJ f 47.998 4.2684 56.7279 39.2681
FVB/NJ m 46.12 6.749 59.9232 32.3168


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 42.845 3.8965 50.8143 34.8757
129X1/SvJ both 27.3192 4.3564 36.2291 18.4093
A/J both 44.895 3.8965 52.8643 36.9257
BALB/cByJ both 32.8717 3.8965 40.8409 24.9024
C57BL/6J both 31.9067 3.8965 39.8759 23.9374
CBA/J both 28.8317 4.3564 37.7416 19.9218
DBA/2J both 38.4 4.7722 48.1603 28.6397
FVB/NJ both 47.059 3.9927 55.2251 38.8929




  GWAS USING LINEAR MIXED MODELS