Project measure / variable:   Poon1   RMS_M03

ID, description, units MPD:47501   RMS_M03   BrdU+ cells of rostral migratory stream   [n/mm]  at age 3mo  
Data set, strains Poon1   inbred   9 strains     sex: both
Procedure histopathology
Ontology mappings

  STRAIN COMPARISON PLOT
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Poon1 - BrdU+ cells of rostral migratory stream at age 3mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means73.9   n/mm 68.6   n/mm
Median of the strain means70.7   n/mm 75.6   n/mm
SD of the strain means± 17.2 ± 16.5
Coefficient of variation (CV)0.233 0.240
Min–max range of strain means47.8   –   103   n/mm 33.8   –   91.3   n/mm
Mean sample size per strain2.9   mice 2.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 153.6843 153.6843 0.9321 0.3413
strain 8 8016.3734 1002.0467 6.0776 0.0001
sex:strain 8 4826.3275 603.2909 3.6591 0.0037
Residuals 33 5440.868 164.8748


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 73.1 2.91   2   2.06 0.0398 71.0, 75.1 -0.05
129S1/SvImJ m 75.6 11.8   3 6.84 0.157 62.0, 84.1 0.43
129X1/SvJ f 103.0 23.1   3 13.3 0.224 82.7, 128.0 1.69
129X1/SvJ m 75.7 6.19   3 3.58 0.0818 68.9, 81.0 0.43
A/J f 66.6 20.1   2   14.2 0.302 52.4, 80.8 -0.42
A/J m 67.8 3.03   4 1.51 0.0446 63.4, 70.2 -0.05
BALB/cByJ f 88.9 17.3   3 9.98 0.194 71.8, 106.0 0.87
BALB/cByJ m 55.0 4.45   3 2.57 0.081 50.8, 59.7 -0.83
C3H/HeJ f 56.6 15.4   3 8.91 0.273 46.4, 74.4 -1.01
C3H/HeJ m 91.3 14.7   3 8.47 0.161 74.4, 101.0 1.38
C57BL/6J f 47.8 14.6   4 7.29 0.305 32.1, 61.9 -1.52
C57BL/6J m 33.8 0.346   2   0.245 0.0102 33.6, 34.1 -2.11
CBA/J f 69.4 7.72   3 4.46 0.111 60.6, 75.1 -0.26
CBA/J m 64.3 23.1   2   16.3 0.359 48.0, 80.6 -0.26
DBA/2J f 70.7 7.77   3 4.49 0.11 63.4, 78.8 -0.19
DBA/2J m 77.3 0.247   2   0.175 0.0032 77.1, 77.4 0.53
FVB/NJ f 89.1 16.0   3 9.22 0.179 74.0, 106.0 0.88
FVB/NJ m 76.4 7.55   3 4.36 0.0989 68.7, 83.8 0.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 73.065 9.0795 91.5374 54.5926
129S1/SvImJ m 75.5667 7.4134 90.6493 60.484
129X1/SvJ f 102.86 7.4134 117.9426 87.7774
129X1/SvJ m 75.6933 7.4134 90.776 60.6107
A/J f 66.59 9.0795 85.0624 48.1176
A/J m 67.795 6.4202 80.857 54.733
BALB/cByJ f 88.92 7.4134 104.0026 73.8374
BALB/cByJ m 54.9867 7.4134 70.0693 39.904
C3H/HeJ f 56.6 7.4134 71.6826 41.5174
C3H/HeJ m 91.3 7.4134 106.3826 76.2174
C57BL/6J f 47.845 6.4202 60.907 34.783
C57BL/6J m 33.825 9.0795 52.2974 15.3526
CBA/J f 69.4333 7.4134 84.516 54.3507
CBA/J m 64.26 9.0795 82.7324 45.7876
DBA/2J f 70.7233 7.4134 85.806 55.6407
DBA/2J m 77.265 9.0795 95.7374 58.7926
FVB/NJ f 89.1167 7.4134 104.1993 74.034
FVB/NJ m 76.3667 7.4134 91.4493 61.284


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 74.3158 5.8608 86.2397 62.392
129X1/SvJ both 89.2767 5.2421 99.9417 78.6116
A/J both 67.1925 5.56 78.5045 55.8805
BALB/cByJ both 71.9533 5.2421 82.6184 61.2883
C3H/HeJ both 73.95 5.2421 84.615 63.285
C57BL/6J both 40.835 5.56 52.147 29.523
CBA/J both 66.8467 5.8608 78.7705 54.9228
DBA/2J both 73.9942 5.8608 85.918 62.0703
FVB/NJ both 82.7417 5.2421 93.4067 72.0766




  GWAS USING LINEAR MIXED MODELS