Project measure / variable:   HMDPpheno2   CHOL_un

ID, description, units MPD:46403   CHOL_un   unesterified cholesterol (plasma CHOL)   [mg/dL]  
Data set, strains HMDPpheno2   HMDP w/par   99 strains     sex: m     age: 16wks
Procedure lipid profile
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno2 - unesterified cholesterol (plasma CHOL)



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested99 strains
Mean of the strain means22.3   mg/dL
Median of the strain means21.2   mg/dL
SD of the strain means± 10.1
Coefficient of variation (CV)0.451
Min–max range of strain means5.67   –   59.0   mg/dL
Mean sample size per strain6.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 97 67990.9364 700.9375 23.7308 < 0.0001
Residuals 562 16599.8454 29.5371


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 29.6 2.26   8 0.8 0.0764 26.0, 32.0 0.72
A/J m 13.3 2.07   6 0.843 0.155 10.0, 16.0 -0.9
AKR/J m 17.8 2.19   8 0.773 0.123 14.0, 20.0 -0.45
AXB10/PgnJ m 9.2 1.1   5 0.49 0.119 8.0, 11.0 -1.3
AXB12/PgnJ m 18.2 2.86   6 1.17 0.157 14.0, 22.0 -0.41
AXB13/PgnJ m 12.2 4.36   6 1.78 0.358 8.0, 17.0 -1.01
AXB15/PgnJ m 8.5 2.17   6 0.885 0.255 6.0, 12.0 -1.37
AXB19a/PgnJ m 13.0 1.58   5 0.707 0.122 11.0, 15.0 -0.93
AXB19b/PgnJ m 8.25 3.69   8 1.31 0.448 3.0, 16.0 -1.4
AXB19/PgnJ m 5.67 1.63   6 0.667 0.288 3.0, 7.0 -1.65
AXB1/PgnJ m 24.2 1.71   4 0.854 0.0704 22.0, 26.0 0.18
AXB23/PgnJ m 8.83 3.82   6 1.56 0.432 3.0, 14.0 -1.34
AXB24/PgnJ m 12.6 3.29   5 1.47 0.261 9.0, 16.0 -0.97
AXB2/PgnJ m 24.8 5.38   6 2.2 0.217 17.0, 29.0 0.24
AXB4/PgnJ m 14.2 2.71   6 1.11 0.192 11.0, 19.0 -0.81
AXB5/PgnJ m 11.5 1.0   4 0.5 0.087 10.0, 12.0 -1.08
AXB6/PgnJ m 11.8 1.04   8 0.366 0.0881 10.0, 13.0 -1.05
AXB8/PgnJ m 18.0 3.54   5 1.58 0.196 12.0, 21.0 -0.43
B6cC3-1/KccJ m 25.7 3.98   6 1.63 0.155 21.0, 31.0 0.33
BALB/cJ m 20.5 3.21   10 1.01 0.156 14.0, 25.0 -0.18
BTBR T+ Itpr3tf/J m 30.8 3.88   10 1.23 0.126 25.0, 39.0 0.84
BUB/BnJ m 24.2 3.38   9 1.13 0.14 17.0, 28.0 0.18
BXA11/PgnJ m 19.7 2.07   6 0.843 0.105 18.0, 23.0 -0.26
BXA12/PgnJ m 11.8 4.99   4 2.5 0.425 5.0, 17.0 -1.05
BXA13/PgnJ m 19.2 3.25   6 1.33 0.17 15.0, 23.0 -0.31
BXA14/PgnJ m 26.2 6.37   6 2.6 0.243 19.0, 35.0 0.38
BXA16/PgnJ m 23.1 2.67   7 1.01 0.115 18.0, 25.0 0.07
BXA1/PgnJ m 13.0 1.41   2   1.0 0.109 12.0, 14.0 -0.93
BXA24/PgnJ m 23.2 5.04   6 2.06 0.217 16.0, 29.0 0.08
BXA25/PgnJ m 17.2 2.32   6 0.946 0.135 13.0, 20.0 -0.51
BXA26/PgnJ m 9.0 2.0   6 0.816 0.222 6.0, 11.0 -1.32
BXA2/PgnJ m 13.5 3.15   6 1.28 0.233 8.0, 17.0 -0.88
BXA4/PgnJ m 17.0 3.87   5 1.73 0.228 13.0, 22.0 -0.53
BXA7/PgnJ m 16.3 2.07   6 0.843 0.126 14.0, 20.0 -0.6
BXA8/PgnJ m 9.5 1.64   6 0.671 0.173 7.0, 12.0 -1.27
BXD11/TyJ m 24.2 3.11   5 1.39 0.129 19.0, 27.0 0.18
BXD12/TyJ m 21.0 9.17   6 3.74 0.436 12.0, 33.0 -0.13
BXD13/TyJ m 13.2 2.64   6 1.08 0.2 11.0, 17.0 -0.91
BXD14/TyJ m 22.5 3.39   6 1.38 0.151 19.0, 28.0 0.02
BXD15/TyJ m 10.5 3.7   4 1.85 0.352 6.0, 14.0 -1.17
BXD16/TyJ m 18.2 1.71   4 0.854 0.0936 16.0, 20.0 -0.41
BXD18/TyJ m 12.0 2.83   2   2.0 0.236 10.0, 14.0 -1.03
BXD19/TyJ m 18.5 2.88   8 1.02 0.156 14.0, 23.0 -0.38
BXD1/TyJ m 20.2 2.06   4 1.03 0.102 18.0, 23.0 -0.21
BXD20/TyJ m 21.7 6.47   6 2.64 0.299 12.0, 31.0 -0.06
BXD21/TyJ m 14.8 3.59   4 1.8 0.244 10.0, 18.0 -0.75
BXD22/TyJ m 26.0 0.0   1   0.0 0.0 26.0, 26.0 0.36
BXD24/TyJ-Cep290rd16/J m 13.5 1.38   6 0.563 0.102 11.0, 15.0 -0.88
BXD27/TyJ m 33.2 7.63   4 3.82 0.23 22.0, 38.0 1.08
BXD28/TyJ m 24.8 8.67   5 3.88 0.35 18.0, 40.0 0.24
BXD29-Tlr4lps-2J/J m 16.5 4.04   6 1.65 0.245 13.0, 24.0 -0.58
BXD2/TyJ m 24.8 7.41   4 3.71 0.299 18.0, 33.0 0.24
BXD31/TyJ m 22.2 4.35   4 2.17 0.195 18.0, 28.0 -0.01
BXD32/TyJ m 19.0 2.94   4 1.47 0.155 15.0, 22.0 -0.33
BXD33/TyJ m 15.2 4.22   6 1.72 0.278 9.0, 20.0 -0.71
BXD34/TyJ m 23.0 2.68   6 1.1 0.117 20.0, 27.0 0.06
BXD36/TyJ m 22.0 5.35   4 2.68 0.243 16.0, 27.0 -0.03
BXD38/TyJ m 12.2 0.957   4 0.479 0.0782 11.0, 13.0 -1.01
BXD39/TyJ m 13.6 1.52   5 0.678 0.112 12.0, 15.0 -0.87
BXD40/TyJ m 17.3 2.66   6 1.09 0.153 15.0, 22.0 -0.5
BXD42/TyJ m 29.3 3.93   6 1.61 0.134 25.0, 36.0 0.69
BXD5/TyJ m 29.2 1.33   6 0.543 0.0456 27.0, 31.0 0.68
BXD6/TyJ m 16.2 1.72   6 0.703 0.107 13.0, 18.0 -0.61
BXD8/TyJ m 16.3 3.01   6 1.23 0.184 13.0, 20.0 -0.6
BXD9/TyJ m 21.8 3.13   6 1.28 0.143 18.0, 26.0 -0.05
BXH10/TyJ m 18.5 3.94   6 1.61 0.213 11.0, 22.0 -0.38
BXH14/TyJ m 42.7 5.89   9 1.96 0.138 33.0, 49.0 2.02
BXH19/TyJ m 31.2 4.46   17 1.08 0.143 24.0, 39.0 0.88
BXH20/KccJ m 31.9 5.74   8 2.03 0.18 24.0, 39.0 0.95
BXH22/KccJ m 20.1 3.67   10 1.16 0.182 15.0, 27.0 -0.22
BXH2/TyJ m 21.0 2.96   9 0.986 0.141 19.0, 28.0 -0.13
BXH4/TyJ m 25.5 9.42   11 2.84 0.369 14.0, 45.0 0.31
BXH6/TyJ m 36.8 9.83   10 3.11 0.267 22.0, 52.0 1.43
BXH7/TyJ m 21.2 7.15   10 2.26 0.337 15.0, 40.0 -0.11
BXH8/TyJ m 27.7 4.36   11 1.31 0.157 21.0, 33.0 0.53
BXH9/TyJ m 44.1 14.0   8 4.95 0.317 15.0, 62.0 2.16
C3H/HeJ m 35.6 2.0   8 0.706 0.056 32.0, 38.0 1.31
C57BL/6J m 22.6 6.91   9 2.3 0.306 11.0, 32.0 0.02
C57L/J m 25.8 7.74   10 2.45 0.3 10.0, 35.0 0.34
C58/J m 25.0 2.05   10 0.65 0.0822 21.0, 27.0 0.26
CBA/J m 21.2 3.37   8 1.19 0.159 17.0, 26.0 -0.11
CE/J m 27.1 7.54   9 2.51 0.278 17.0, 41.0 0.47
DBA/2J m 30.1 4.09   8 1.44 0.136 27.0, 39.0 0.77
FVB/NJ m 49.3 5.51   3 3.18 0.112 44.0, 55.0 2.67
I/LnJ m 23.0 7.04   9 2.35 0.306 9.0, 34.0 0.06
KK/HlJ m 45.8 9.39   8 3.32 0.205 30.0, 58.0 2.33
LG/J m 43.9 7.84   7 2.96 0.179 33.0, 57.0 2.14
LP/J m 28.1 3.31   10 1.05 0.118 20.0, 32.0 0.57
MA/MyJ m 35.2 4.83   6 1.97 0.137 30.0, 43.0 1.27
NOD/ShiLtJ m 30.8 8.14   8 2.88 0.265 17.0, 45.0 0.84
NON/ShiLtJ m 38.9 9.48   11 2.86 0.244 22.0, 56.0 1.64
NZB/BlNJ m 59.0 6.38   7 2.41 0.108 50.0, 68.0 3.63
NZW/LacJ m 45.3 4.5   10 1.42 0.0993 36.0, 51.0 2.28
PL/J m 31.2 13.7   6 5.6 0.44 19.0, 51.0 0.88
RIIIS/J m 11.8 2.15   10 0.68 0.182 8.0, 15.0 -1.05
SEA/GnJ m 12.2 5.38   11 1.62 0.442 6.0, 22.0 -1.01
SJL/J m 17.0 4.24   2   3.0 0.25 14.0, 20.0 -0.53
SM/J m 33.0 10.3   10 3.27 0.313 17.0, 47.0 1.06
SWR/J m 25.4 7.55   7 2.85 0.297 15.0, 34.0 0.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ m 29.625 1.9215 33.3992 25.8508
A/J m 13.3333 2.2187 17.6914 8.9753
AKR/J m 17.75 1.9215 21.5242 13.9758
AXB10/PgnJ m 9.2 2.4305 13.974 4.426
AXB12/PgnJ m 18.1667 2.2187 22.5247 13.8086
AXB13/PgnJ m 12.1667 2.2187 16.5247 7.8086
AXB15/PgnJ m 8.5 2.2187 12.8581 4.1419
AXB19a/PgnJ m 13.0 2.4305 17.774 8.226
AXB19b/PgnJ m 8.25 1.9215 12.0242 4.4758
AXB19/PgnJ m 5.6667 2.2187 10.0247 1.3086
AXB1/PgnJ m 24.25 2.7174 29.5875 18.9125
AXB23/PgnJ m 8.8333 2.2187 13.1914 4.4753
AXB24/PgnJ m 12.6 2.4305 17.374 7.826
AXB2/PgnJ m 24.8333 2.2187 29.1914 20.4753
AXB4/PgnJ m 14.1667 2.2187 18.5247 9.8086
AXB5/PgnJ m 11.5 2.7174 16.8375 6.1625
AXB6/PgnJ m 11.75 1.9215 15.5242 7.9758
AXB8/PgnJ m 18.0 2.4305 22.774 13.226
B6cC3-1/KccJ m 25.6667 2.2187 30.0247 21.3086
BALB/cJ m 20.5 1.7186 23.8757 17.1243
BTBR T+ Itpr3tf/J m 30.8 1.7186 34.1757 27.4243
BUB/BnJ m 24.2222 1.8116 27.7806 20.6639
BXA11/PgnJ m 19.6667 2.2187 24.0247 15.3086
BXA12/PgnJ m 11.75 2.7174 17.0875 6.4125
BXA13/PgnJ m 19.1667 2.2187 23.5247 14.8086
BXA14/PgnJ m 26.1667 2.2187 30.5247 21.8086
BXA16/PgnJ m 23.1429 2.0542 27.1776 19.1081
BXA1/PgnJ m 13.0 3.843 20.5484 5.4516
BXA24/PgnJ m 23.1667 2.2187 27.5247 18.8086
BXA25/PgnJ m 17.1667 2.2187 21.5247 12.8086
BXA26/PgnJ m 9.0 2.2187 13.3581 4.6419
BXA2/PgnJ m 13.5 2.2187 17.8581 9.1419
BXA4/PgnJ m 17.0 2.4305 21.774 12.226
BXA7/PgnJ m 16.3333 2.2187 20.6914 11.9753
BXA8/PgnJ m 9.5 2.2187 13.8581 5.1419
BXD11/TyJ m 24.2 2.4305 28.974 19.426
BXD12/TyJ m 21.0 2.2187 25.3581 16.6419
BXD13/TyJ m 13.1667 2.2187 17.5247 8.8086
BXD14/TyJ m 22.5 2.2187 26.8581 18.1419
BXD15/TyJ m 10.5 2.7174 15.8375 5.1625
BXD16/TyJ m 18.25 2.7174 23.5875 12.9125
BXD18/TyJ m 12.0 3.843 19.5484 4.4516
BXD19/TyJ m 18.5 1.9215 22.2742 14.7258
BXD1/TyJ m 20.25 2.7174 25.5875 14.9125
BXD20/TyJ m 21.6667 2.2187 26.0247 17.3086
BXD21/TyJ m 14.75 2.7174 20.0875 9.4125
BXD24/TyJ-Cep290rd16/J m 13.5 2.2187 17.8581 9.1419
BXD27/TyJ m 33.25 2.7174 38.5875 27.9125
BXD28/TyJ m 24.8 2.4305 29.574 20.026
BXD29-Tlr4lps-2J/J m 16.5 2.2187 20.8581 12.1419
BXD2/TyJ m 24.75 2.7174 30.0875 19.4125
BXD31/TyJ m 22.25 2.7174 27.5875 16.9125
BXD32/TyJ m 19.0 2.7174 24.3375 13.6625
BXD33/TyJ m 15.1667 2.2187 19.5247 10.8086
BXD34/TyJ m 23.0 2.2187 27.3581 18.6419
BXD36/TyJ m 22.0 2.7174 27.3375 16.6625
BXD38/TyJ m 12.25 2.7174 17.5875 6.9125
BXD39/TyJ m 13.6 2.4305 18.374 8.826
BXD40/TyJ m 17.3333 2.2187 21.6914 12.9753
BXD42/TyJ m 29.3333 2.2187 33.6914 24.9753
BXD5/TyJ m 29.1667 2.2187 33.5247 24.8086
BXD6/TyJ m 16.1667 2.2187 20.5247 11.8086
BXD8/TyJ m 16.3333 2.2187 20.6914 11.9753
BXD9/TyJ m 21.8333 2.2187 26.1914 17.4753
BXH10/TyJ m 18.5 2.2187 22.8581 14.1419
BXH14/TyJ m 42.6667 1.8116 46.225 39.1083
BXH19/TyJ m 31.1765 1.3181 33.7655 28.5874
BXH20/KccJ m 31.875 1.9215 35.6492 28.1008
BXH22/KccJ m 20.1 1.7186 23.4757 16.7243
BXH2/TyJ m 21.0 1.8116 24.5583 17.4417
BXH4/TyJ m 25.5455 1.6387 28.7641 22.3268
BXH6/TyJ m 36.8 1.7186 40.1757 33.4243
BXH7/TyJ m 21.2 1.7186 24.5757 17.8243
BXH8/TyJ m 27.7273 1.6387 30.9459 24.5086
BXH9/TyJ m 44.125 1.9215 47.8992 40.3508
C3H/HeJ m 35.625 1.9215 39.3992 31.8508
C57BL/6J m 22.5556 1.8116 26.1139 18.9972
C57L/J m 25.8 1.7186 29.1757 22.4243
C58/J m 25.0 1.7186 28.3757 21.6243
CBA/J m 21.25 1.9215 25.0242 17.4758
CE/J m 27.1111 1.8116 30.6694 23.5528
DBA/2J m 30.125 1.9215 33.8992 26.3508
FVB/NJ m 49.3333 3.1378 55.4966 43.1701
I/LnJ m 23.0 1.8116 26.5583 19.4417
KK/HlJ m 45.75 1.9215 49.5242 41.9758
LG/J m 43.8571 2.0542 47.8919 39.8224
LP/J m 28.1 1.7186 31.4757 24.7243
MA/MyJ m 35.1667 2.2187 39.5247 30.8086
NOD/ShiLtJ m 30.75 1.9215 34.5242 26.9758
NON/ShiLtJ m 38.9091 1.6387 42.1277 35.6905
NZB/BlNJ m 59.0 2.0542 63.0348 54.9652
NZW/LacJ m 45.3 1.7186 48.6757 41.9243
PL/J m 31.1667 2.2187 35.5247 26.8086
RIIIS/J m 11.8 1.7186 15.1757 8.4243
SEA/GnJ m 12.1818 1.6387 15.4005 8.9632
SJL/J m 17.0 3.843 24.5484 9.4516
SM/J m 33.0 1.7186 36.3757 29.6243
SWR/J m 25.4286 2.0542 29.4633 21.3938




  GWAS USING LINEAR MIXED MODELS