Project measure / variable:   Donahue16   total_wt

ID, description, units MPD:42802   total_wt   total tissue mass, head excluded   [g]  
Data set, strains Donahue16   B6.A consomic w/par   23 strains     sex: both     age: 24-29wks
Procedure DXA
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  STRAIN COMPARISON PLOT
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Donahue16 - total tissue mass, head excluded



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains23 strains
Mean of the strain means21.5   g 27.9   g
Median of the strain means22.0   g 28.0   g
SD of the strain means± 2.43 ± 2.75
Coefficient of variation (CV)0.113 0.0985
Min–max range of strain means16.7   –   27.4   g 22.2   –   36.2   g
Mean sample size per strain9.7   mice 9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4442.3583 4442.3583 417.7696 < 0.0001
strain 21 1747.3589 83.2076 7.825 < 0.0001
sex:strain 21 729.5006 34.7381 3.2669 < 0.0001
Residuals 384 4083.2691 10.6335


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 23.0 2.42   8 0.856 0.105 19.8, 26.4 0.62
A/J m 22.2 1.87   5 0.835 0.0842 20.5, 25.0 -2.07
B6.A-Chr1 f 25.1 3.86   9 1.29 0.153 17.2, 29.8 1.48
B6.A-Chr1 m 30.9 2.78   10 0.878 0.0898 26.9, 35.7 1.1
B6.A-Chr10 f 18.7 2.54   10 0.804 0.136 16.1, 23.9 -1.15
B6.A-Chr10 m 27.2 5.47   12 1.58 0.201 22.0, 41.3 -0.25
B6.A-Chr11 f 18.4 1.49   6 0.609 0.081 16.8, 20.7 -1.27
B6.A-Chr11 m 26.8 4.85   12 1.4 0.181 21.0, 35.1 -0.39
B6.A-Chr12 f 22.3 4.23   11 1.27 0.19 17.9, 33.1 0.33
B6.A-Chr12 m 25.5 2.2   9 0.732 0.0861 23.3, 30.9 -0.87
B6.A-Chr13 f 27.4 4.65   9 1.55 0.17 22.3, 33.1 2.43
B6.A-Chr13 m 28.4 3.13   10 0.989 0.11 24.4, 35.9 0.19
B6.A-Chr14 f 22.9 2.89   10 0.915 0.126 17.6, 26.9 0.58
B6.A-Chr14 m 29.1 4.48   9 1.49 0.154 23.6, 36.3 0.44
B6.A-Chr15 f 22.7 3.15   10 0.996 0.139 16.3, 26.4 0.5
B6.A-Chr15 m 29.2 3.32   10 1.05 0.114 24.0, 34.3 0.48
B6.A-Chr16 f 22.5 1.35   7 0.51 0.06 20.9, 24.5 0.41
B6.A-Chr16 m 29.0 4.07   5 1.82 0.14 24.0, 34.6 0.41
B6.A-Chr17 f 20.1 2.33   14 0.623 0.116 16.2, 23.8 -0.57
B6.A-Chr17 m 28.0 2.71   18 0.64 0.0969 24.0, 33.9 0.04
B6.A-Chr18 f 21.1 5.36   11 1.62 0.254 15.4, 31.1 -0.16
B6.A-Chr18 m 25.5 2.82   8 0.996 0.111 22.4, 30.3 -0.87
B6.A-Chr19 f 21.9 3.83   10 1.21 0.175 15.9, 27.0 0.17
B6.A-Chr19 m 29.2 2.35   9 0.785 0.0807 25.6, 32.1 0.48
B6.A-Chr2 f 22.4 3.86   9 1.29 0.172 15.2, 29.1 0.37
B6.A-Chr2 m 28.4 5.15   8 1.82 0.181 22.5, 37.5 0.19
B6.A-Chr3 f 17.3 2.22   13 0.617 0.128 13.1, 21.5 -1.72
B6.A-Chr3 m 25.8 1.96   11 0.591 0.0759 23.7, 30.1 -0.76
B6.A-Chr4 f 16.7 1.37   8 0.484 0.0819 14.6, 19.0 -1.97
B6.A-Chr4 m 24.2 1.14   8 0.402 0.047 22.2, 25.9 -1.34
B6.A-Chr5 f 22.2 2.16   8 0.763 0.0971 19.6, 25.8 0.29
B6.A-Chr5 m 36.2 2.53   8 0.896 0.07 33.3, 39.6 3.03
B6.A-Chr6 f 22.3 1.67   8 0.59 0.0749 20.2, 24.8 0.33
B6.A-Chr6 m 29.2 3.58   9 1.19 0.122 25.5, 35.8 0.48
B6.A-Chr7 f 21.0 2.16   8 0.764 0.103 18.3, 24.8 -0.2
B6.A-Chr7 m 27.6 3.54   9 1.18 0.128 22.3, 33.0 -0.1
B6.A-Chr8 f 19.5 2.52   12 0.727 0.129 15.6, 26.4 -0.82
B6.A-Chr8 m 25.7 4.29   11 1.29 0.167 19.2, 33.4 -0.79
B6.A-Chr9 f 21.9 2.06   9 0.687 0.0941 19.0, 24.6 0.17
B6.A-Chr9 m 26.1 2.54   10 0.803 0.0973 22.3, 30.1 -0.65
B6.A-ChrX f 20.6 2.88   12 0.832 0.14 16.6, 24.2 -0.37
B6.A-ChrX m 27.6 3.35   13 0.929 0.121 23.8, 33.5 -0.1
B6.A-ChrY m 28.9 5.1   9 1.7 0.176 24.3, 38.1 0.37
C57BL/6J f 22.8 1.9   12 0.548 0.083 20.1, 26.1 0.54
C57BL/6J m 30.5 3.65   10 1.15 0.12 24.4, 36.3 0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 23.0125 1.1529 25.2793 20.7457
A/J m 22.16 1.4583 25.0273 19.2927
B6.A-Chr1 f 25.1333 1.087 27.2705 22.9962
B6.A-Chr1 m 30.94 1.0312 32.9675 28.9125
B6.A-Chr10 f 18.72 1.0312 20.7475 16.6925
B6.A-Chr10 m 27.1667 0.9413 29.0175 25.3158
B6.A-Chr11 f 18.4333 1.3313 21.0508 15.8159
B6.A-Chr11 m 26.7583 0.9413 28.6092 24.9075
B6.A-Chr12 f 22.2818 0.9832 24.2149 20.3487
B6.A-Chr12 m 25.5 1.087 27.6372 23.3628
B6.A-Chr13 f 27.4222 1.087 29.5594 25.2851
B6.A-Chr13 m 28.35 1.0312 30.3775 26.3225
B6.A-Chr14 f 22.92 1.0312 24.9475 20.8925
B6.A-Chr14 m 29.0889 1.087 31.226 26.9517
B6.A-Chr15 f 22.7 1.0312 24.7275 20.6725
B6.A-Chr15 m 29.23 1.0312 31.2575 27.2025
B6.A-Chr16 f 22.4857 1.2325 24.909 20.0624
B6.A-Chr16 m 28.98 1.4583 31.8473 26.1127
B6.A-Chr17 f 20.1143 0.8715 21.8278 18.4007
B6.A-Chr17 m 28.0222 0.7686 29.5334 26.511
B6.A-Chr18 f 21.1091 0.9832 23.0422 19.176
B6.A-Chr18 m 25.4625 1.1529 27.7293 23.1957
B6.A-Chr19 f 21.88 1.0312 23.9075 19.8525
B6.A-Chr19 m 29.1889 1.087 31.326 27.0517
B6.A-Chr2 f 22.4444 1.087 24.5816 20.3073
B6.A-Chr2 m 28.375 1.1529 30.6418 26.1082
B6.A-Chr3 f 17.3462 0.9044 19.1244 15.5679
B6.A-Chr3 m 25.8182 0.9832 27.7513 23.8851
B6.A-Chr4 f 16.7125 1.1529 18.9793 14.4457
B6.A-Chr4 m 24.2125 1.1529 26.4793 21.9457
B6.A-Chr5 f 22.225 1.1529 24.4918 19.9582
B6.A-Chr5 m 36.1875 1.1529 38.4543 33.9207
B6.A-Chr6 f 22.3 1.1529 24.5668 20.0332
B6.A-Chr6 m 29.2444 1.087 31.3816 27.1073
B6.A-Chr7 f 21.025 1.1529 23.2918 18.7582
B6.A-Chr7 m 27.6222 1.087 29.7594 25.4851
B6.A-Chr8 f 19.5333 0.9413 21.3842 17.6825
B6.A-Chr8 m 25.7364 0.9832 27.6695 23.8032
B6.A-Chr9 f 21.9111 1.087 24.0483 19.774
B6.A-Chr9 m 26.11 1.0312 28.1375 24.0825
B6.A-ChrX f 20.6 0.9413 22.4508 18.7492
B6.A-ChrX m 27.5836 0.9044 29.3618 25.8054
C57BL/6J f 22.8417 0.9413 24.6925 20.9908
C57BL/6J m 30.47 1.0312 32.4975 28.4425


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 22.5862 0.9295 24.4138 20.7587
B6.A-Chr1 both 28.0367 0.7491 29.5096 26.5637
B6.A-Chr10 both 22.9433 0.6981 24.3159 21.5707
B6.A-Chr11 both 22.5958 0.8152 24.1987 20.993
B6.A-Chr12 both 23.8909 0.7328 25.3318 22.45
B6.A-Chr13 both 27.8861 0.7491 29.359 26.4132
B6.A-Chr14 both 26.0044 0.7491 27.4774 24.5315
B6.A-Chr15 both 25.965 0.7292 27.3986 24.5314
B6.A-Chr16 both 25.7329 0.9547 27.6099 23.8558
B6.A-Chr17 both 24.0683 0.581 25.2106 22.9259
B6.A-Chr18 both 23.2858 0.7576 24.7754 21.7962
B6.A-Chr19 both 25.5344 0.7491 27.0074 24.0615
B6.A-Chr2 both 25.4097 0.7923 26.9674 23.852
B6.A-Chr3 both 21.5822 0.668 22.8955 20.2689
B6.A-Chr4 both 20.4625 0.8152 22.0654 18.8596
B6.A-Chr5 both 29.2063 0.8152 30.8091 27.6034
B6.A-Chr6 both 25.7722 0.7923 27.3299 24.2145
B6.A-Chr7 both 24.3236 0.7923 25.8813 22.7659
B6.A-Chr8 both 22.6348 0.6806 23.973 21.2967
B6.A-Chr9 both 24.0106 0.7491 25.4835 22.5376
B6.A-ChrX both 24.0918 0.6527 25.3751 22.8085
C57BL/6J both 26.6558 0.6981 28.0284 25.2832




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA