Project measure / variable:   Chang2   cataract_punctate

ID, description, units MPD:42703   cataract_punctate   punctate cataract   [frequency rate]  
Data set, strains Chang2   B6.PWD consomic w/par   28 strains     sex: both     age: 44-61wks
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  STRAIN COMPARISON PLOT
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Chang2 - punctate cataract



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means0.281   frequency rate 0.276   frequency rate
Median of the strain means0.250   frequency rate 0.250   frequency rate
SD of the strain means± 0.175 ± 0.171
Coefficient of variation (CV)0.622 0.622
Min–max range of strain means0   –   0.889   frequency rate 0   –   0.625   frequency rate
Mean sample size per strain8.8   mice 8.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.001 0.001 0.0053 0.9419
strain 27 8.4963 0.3147 1.6368 0.0246
sex:strain 27 5.6868 0.2106 1.0955 0.3405
Residuals 424 81.5159 0.1923


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 0.375 0.518   8 0.183 1.38 0.54
B6.PWD-Chr1 m 0.444 0.527   9 0.176 1.19 0.98
B6.PWD-Chr10.1 f 0.25 0.463   8 0.164 1.85 -0.17
B6.PWD-Chr10.1 m 0.2 0.422   10 0.133 2.11 -0.44
B6.PWD-Chr10.2 f 0.1 0.316   10 0.1 3.16 -1.03
B6.PWD-Chr10.2 m 0.0 0.0   8 0.0 0.0 -1.61
B6.PWD-Chr10.3 f 0.429 0.535   7 0.202 1.25 0.85
B6.PWD-Chr10.3 m 0.5 0.535   8 0.189 1.07 1.31
B6.PWD-Chr11.1 f 0.25 0.463   8 0.164 1.85 -0.17
B6.PWD-Chr11.1 m 0.375 0.518   8 0.183 1.38 0.58
B6.PWD-Chr11.2 f 0.286 0.488   7 0.184 1.71 0.03
B6.PWD-Chr11.2 m 0.375 0.518   8 0.183 1.38 0.58
B6.PWD-Chr11.3 f 0.143 0.378   7 0.143 2.65 -0.79
B6.PWD-Chr11.3 m 0.222 0.441   9 0.147 1.98 -0.31
B6.PWD-Chr12 f 0.222 0.441   9 0.147 1.98 -0.34
B6.PWD-Chr12 m 0.125 0.354   8 0.125 2.83 -0.88
B6.PWD-Chr13 f 0.375 0.518   8 0.183 1.38 0.54
B6.PWD-Chr13 m 0.375 0.518   8 0.183 1.38 0.58
B6.PWD-Chr14 f 0.222 0.441   9 0.147 1.98 -0.34
B6.PWD-Chr14 m 0.111 0.333   9 0.111 3.0 -0.96
B6.PWD-Chr15 f 0.111 0.333   9 0.111 3.0 -0.97
B6.PWD-Chr15 m 0.125 0.354   8 0.125 2.83 -0.88
B6.PWD-Chr16 f 0.182 0.405   11 0.122 2.22 -0.56
B6.PWD-Chr16 m 0.25 0.463   8 0.164 1.85 -0.15
B6.PWD-Chr17 f 0.375 0.518   8 0.183 1.38 0.54
B6.PWD-Chr17 m 0.625 0.518   8 0.183 0.828 2.04
B6.PWD-Chr18 f 0.25 0.463   8 0.164 1.85 -0.17
B6.PWD-Chr18 m 0.125 0.354   8 0.125 2.83 -0.88
B6.PWD-Chr19 f 0.375 0.518   8 0.183 1.38 0.54
B6.PWD-Chr19 m 0.222 0.441   9 0.147 1.98 -0.31
B6.PWD-Chr2 f 0.25 0.463   8 0.164 1.85 -0.17
B6.PWD-Chr2 m 0.375 0.518   8 0.183 1.38 0.58
B6.PWD-Chr3 f 0.25 0.463   8 0.164 1.85 -0.17
B6.PWD-Chr3 m 0.444 0.527   9 0.176 1.19 0.98
B6.PWD-Chr5 f 0.3 0.483   10 0.153 1.61 0.11
B6.PWD-Chr5 m 0.625 0.518   8 0.183 0.828 2.04
B6.PWD-Chr6 f 0.222 0.441   9 0.147 1.98 -0.34
B6.PWD-Chr6 m 0.429 0.535   7 0.202 1.25 0.89
B6.PWD-Chr8 f 0.545 0.522   11 0.157 0.957 1.51
B6.PWD-Chr8 m 0.4 0.516   10 0.163 1.29 0.73
B6.PWD-Chr9 f 0.182 0.405   11 0.122 2.22 -0.56
B6.PWD-Chr9 m 0.125 0.354   8 0.125 2.83 -0.88
B6.PWD-ChrX.1 f 0.25 0.463   8 0.164 1.85 -0.17
B6.PWD-ChrX.1 m 0.25 0.463   8 0.164 1.85 -0.15
B6.PWD-ChrX.2 f 0.3 0.483   10 0.153 1.61 0.11
B6.PWD-ChrX.2 m 0.1 0.316   10 0.1 3.16 -1.02
B6.PWD-ChrX.3 f 0.0 0.0   9 0.0 0.0 -1.61
B6.PWD-ChrX.3 m 0.125 0.354   8 0.125 2.83 -0.88
B6.PWD-ChrY f 0.5 0.535   8 0.189 1.07 1.26
B6.PWD-ChrY m 0.375 0.518   8 0.183 1.38 0.58
B6.PWD-mt f 0.222 0.441   9 0.147 1.98 -0.34
B6.PWD-mt m 0.25 0.463   8 0.164 1.85 -0.15
C57BL/6J f 0.889 0.333   9 0.111 0.375 3.48
C57BL/6J m 0.0 0.0   9 0.0 0.0 -1.61
PWD/PhJ f 0.0 0.0   11 0.0 0.0 -1.61
PWD/PhJ m 0.143 0.378   7 0.143 2.65 -0.77


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 0.375 0.155 0.6797 0.0703
B6.PWD-Chr1 m 0.4444 0.1462 0.7317 0.1572
B6.PWD-Chr10.1 f 0.25 0.155 0.5547 -0.0547
B6.PWD-Chr10.1 m 0.2 0.1387 0.4725 -0.0725
B6.PWD-Chr10.2 f 0.1 0.1387 0.3725 -0.1725
B6.PWD-Chr10.2 m 0.0 0.155 0.3047 -0.3047
B6.PWD-Chr10.3 f 0.4286 0.1657 0.7543 0.1028
B6.PWD-Chr10.3 m 0.5 0.155 0.8047 0.1953
B6.PWD-Chr11.1 f 0.25 0.155 0.5547 -0.0547
B6.PWD-Chr11.1 m 0.375 0.155 0.6797 0.0703
B6.PWD-Chr11.2 f 0.2857 0.1657 0.6115 -0.04
B6.PWD-Chr11.2 m 0.375 0.155 0.6797 0.0703
B6.PWD-Chr11.3 f 0.1429 0.1657 0.4686 -0.1829
B6.PWD-Chr11.3 m 0.2222 0.1462 0.5095 -0.0651
B6.PWD-Chr12 f 0.2222 0.1462 0.5095 -0.0651
B6.PWD-Chr12 m 0.125 0.155 0.4297 -0.1797
B6.PWD-Chr13 f 0.375 0.155 0.6797 0.0703
B6.PWD-Chr13 m 0.375 0.155 0.6797 0.0703
B6.PWD-Chr14 f 0.2222 0.1462 0.5095 -0.0651
B6.PWD-Chr14 m 0.1111 0.1462 0.3984 -0.1762
B6.PWD-Chr15 f 0.1111 0.1462 0.3984 -0.1762
B6.PWD-Chr15 m 0.125 0.155 0.4297 -0.1797
B6.PWD-Chr16 f 0.1818 0.1322 0.4417 -0.078
B6.PWD-Chr16 m 0.25 0.155 0.5547 -0.0547
B6.PWD-Chr17 f 0.375 0.155 0.6797 0.0703
B6.PWD-Chr17 m 0.625 0.155 0.9297 0.3203
B6.PWD-Chr18 f 0.25 0.155 0.5547 -0.0547
B6.PWD-Chr18 m 0.125 0.155 0.4297 -0.1797
B6.PWD-Chr19 f 0.375 0.155 0.6797 0.0703
B6.PWD-Chr19 m 0.2222 0.1462 0.5095 -0.0651
B6.PWD-Chr2 f 0.25 0.155 0.5547 -0.0547
B6.PWD-Chr2 m 0.375 0.155 0.6797 0.0703
B6.PWD-Chr3 f 0.25 0.155 0.5547 -0.0547
B6.PWD-Chr3 m 0.4444 0.1462 0.7317 0.1572
B6.PWD-Chr5 f 0.3 0.1387 0.5725 0.0275
B6.PWD-Chr5 m 0.625 0.155 0.9297 0.3203
B6.PWD-Chr6 f 0.2222 0.1462 0.5095 -0.0651
B6.PWD-Chr6 m 0.4286 0.1657 0.7543 0.1028
B6.PWD-Chr8 f 0.5455 0.1322 0.8053 0.2856
B6.PWD-Chr8 m 0.4 0.1387 0.6725 0.1275
B6.PWD-Chr9 f 0.1818 0.1322 0.4417 -0.078
B6.PWD-Chr9 m 0.125 0.155 0.4297 -0.1797
B6.PWD-ChrX.1 f 0.25 0.155 0.5547 -0.0547
B6.PWD-ChrX.1 m 0.25 0.155 0.5547 -0.0547
B6.PWD-ChrX.2 f 0.3 0.1387 0.5725 0.0275
B6.PWD-ChrX.2 m 0.1 0.1387 0.3725 -0.1725
B6.PWD-ChrX.3 f 0.0 0.1462 0.2873 -0.2873
B6.PWD-ChrX.3 m 0.125 0.155 0.4297 -0.1797
B6.PWD-ChrY f 0.5 0.155 0.8047 0.1953
B6.PWD-ChrY m 0.375 0.155 0.6797 0.0703
B6.PWD-mt f 0.2222 0.1462 0.5095 -0.0651
B6.PWD-mt m 0.25 0.155 0.5547 -0.0547
C57BL/6J f 0.8889 0.1462 1.1762 0.6016
C57BL/6J m 0.0 0.1462 0.2873 -0.2873
PWD/PhJ f 0.0 0.1322 0.2599 -0.2599
PWD/PhJ m 0.1429 0.1657 0.4686 -0.1829


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 0.4097 0.1065 0.6191 0.2003
B6.PWD-Chr10.1 both 0.225 0.104 0.4294 0.0206
B6.PWD-Chr10.2 both 0.05 0.104 0.2544 -0.1544
B6.PWD-Chr10.3 both 0.4643 0.1135 0.6873 0.2413
B6.PWD-Chr11.1 both 0.3125 0.1096 0.528 0.097
B6.PWD-Chr11.2 both 0.3304 0.1135 0.5534 0.1073
B6.PWD-Chr11.3 both 0.1825 0.1105 0.3997 -0.0346
B6.PWD-Chr12 both 0.1736 0.1065 0.383 -0.0358
B6.PWD-Chr13 both 0.375 0.1096 0.5905 0.1595
B6.PWD-Chr14 both 0.1667 0.1033 0.3698 -0.0365
B6.PWD-Chr15 both 0.1181 0.1065 0.3274 -0.0913
B6.PWD-Chr16 both 0.2159 0.1019 0.4161 0.0157
B6.PWD-Chr17 both 0.5 0.1096 0.7155 0.2845
B6.PWD-Chr18 both 0.1875 0.1096 0.403 -0.028
B6.PWD-Chr19 both 0.2986 0.1065 0.508 0.0892
B6.PWD-Chr2 both 0.3125 0.1096 0.528 0.097
B6.PWD-Chr3 both 0.3472 0.1065 0.5566 0.1378
B6.PWD-Chr5 both 0.4625 0.104 0.6669 0.2581
B6.PWD-Chr6 both 0.3254 0.1105 0.5426 0.1082
B6.PWD-Chr8 both 0.4727 0.0958 0.661 0.2844
B6.PWD-Chr9 both 0.1534 0.1019 0.3536 -0.0468
B6.PWD-ChrX.1 both 0.25 0.1096 0.4655 0.0345
B6.PWD-ChrX.2 both 0.2 0.098 0.3927 0.0073
B6.PWD-ChrX.3 both 0.0625 0.1065 0.2719 -0.1469
B6.PWD-ChrY both 0.4375 0.1096 0.653 0.222
B6.PWD-mt both 0.2361 0.1065 0.4455 0.0267
C57BL/6J both 0.4444 0.1033 0.6476 0.2413
PWD/PhJ both 0.0714 0.106 0.2798 -0.1369




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA