Project measure / variable:   Johnson3   ABR_16kHz

ID, description, units MPD:42503   ABR_16kHz   auditory brainstem response (ABR) threshold, sound pressure level   [dB]  16 kHz tone stimulus  
Data set, strains Johnson3   B6.A consomic w/par   24 strains     sex: both     age: 23-30wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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Johnson3 - auditory brainstem response (ABR) threshold, sound pressure level 16 kHz tone stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains24 strains
Mean of the strain means27.2   dB 26.0   dB
Median of the strain means21.7   dB 21.2   dB
SD of the strain means± 16.4 ± 16.5
Coefficient of variation (CV)0.602 0.636
Min–max range of strain means17.5   –   90.0   dB 18.9   –   99.0   dB
Mean sample size per strain7.1   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 197.2867 197.2867 2.9721 0.0857
strain 22 73936.8976 3360.7681 50.6302 < 0.0001
sex:strain 22 2788.6246 126.7557 1.9096 0.0092
Residuals 302 20046.3721 66.3787


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 90.0 20.0   4 10.0 0.222 60.0, 100.0 3.83
A/J m 99.0 2.24   5 1.0 0.0226 95.0, 100.0 4.42
B6.A-Chr1 f 21.7 4.08   6 1.67 0.188 20.0, 30.0 -0.34
B6.A-Chr1 m 22.9 3.93   7 1.49 0.172 20.0, 30.0 -0.19
B6.A-Chr10 f 61.7 15.7   15 4.04 0.254 30.0, 80.0 2.11
B6.A-Chr10 m 44.2 17.3   19 3.98 0.392 20.0, 80.0 1.1
B6.A-Chr11 f 35.7 14.6   15 3.78 0.41 20.0, 70.0 0.52
B6.A-Chr11 m 35.0 12.2   16 3.06 0.35 20.0, 70.0 0.55
B6.A-Chr12 f 20.0 2.67   8 0.945 0.134 15.0, 25.0 -0.44
B6.A-Chr12 m 21.2 3.54   8 1.25 0.166 20.0, 30.0 -0.29
B6.A-Chr13 f 25.0 7.07   2   5.0 0.283 20.0, 30.0 -0.13
B6.A-Chr13 m 20.0 0.0   3 0.0 0.0 20.0, 20.0 -0.36
B6.A-Chr14 f 23.3 5.77   3 3.33 0.247 20.0, 30.0 -0.24
B6.A-Chr14 m 21.4 2.44   7 0.922 0.114 20.0, 25.0 -0.28
B6.A-Chr15 f 23.3 5.16   6 2.11 0.221 20.0, 30.0 -0.24
B6.A-Chr15 m 20.6 1.77   8 0.625 0.0857 20.0, 25.0 -0.33
B6.A-Chr16 f 21.1 3.33   9 1.11 0.158 20.0, 30.0 -0.37
B6.A-Chr16 m 20.0 0.0   4 0.0 0.0 20.0, 20.0 -0.36
B6.A-Chr17 f 27.5 4.18   6 1.71 0.152 20.0, 30.0 0.02
B6.A-Chr17 m 21.8 5.41   14 1.45 0.248 20.0, 40.0 -0.25
B6.A-Chr18 f 21.2 3.54   8 1.25 0.166 20.0, 30.0 -0.37
B6.A-Chr18 m 20.0 0.0   4 0.0 0.0 20.0, 20.0 -0.36
B6.A-Chr19 f 25.0 5.77   4 2.89 0.231 20.0, 30.0 -0.13
B6.A-Chr19 m 25.0 7.75   6 3.16 0.31 20.0, 40.0 -0.06
B6.A-Chr2 f 20.0 0.0   7 0.0 0.0 20.0, 20.0 -0.44
B6.A-Chr2 m 20.0 0.0   7 0.0 0.0 20.0, 20.0 -0.36
B6.A-Chr3 f 27.3 12.4   13 3.43 0.452 20.0, 60.0 0.01
B6.A-Chr3 m 20.0 0.0   8 0.0 0.0 20.0, 20.0 -0.36
B6.A-Chr4 f 22.0 2.74   5 1.22 0.124 20.0, 25.0 -0.32
B6.A-Chr4 m 20.0 0.0   6 0.0 0.0 20.0, 20.0 -0.36
B6.A-Chr5 f 17.5 3.54   2   2.5 0.202 15.0, 20.0 -0.59
B6.A-Chr5 m 20.0 0.0   5 0.0 0.0 20.0, 20.0 -0.36
B6.A-Chr6 f 20.0 0.0   6 0.0 0.0 20.0, 20.0 -0.44
B6.A-Chr6 m 23.8 4.79   4 2.39 0.202 20.0, 30.0 -0.13
B6.A-Chr7 f 20.0 2.36   10 0.745 0.118 15.0, 25.0 -0.44
B6.A-Chr7 m 20.0 0.0   8 0.0 0.0 20.0, 20.0 -0.36
B6.A-Chr8 f 20.0 0.0   3 0.0 0.0 20.0, 20.0 -0.44
B6.A-Chr8 m 21.8 4.05   11 1.22 0.185 20.0, 30.0 -0.25
B6.A-Chr9 f 23.3 7.07   9 2.36 0.303 20.0, 40.0 -0.24
B6.A-Chr9 m 22.5 4.25   10 1.34 0.189 20.0, 30.0 -0.21
B6.A-ChrX f 20.5 1.58   10 0.5 0.0771 20.0, 25.0 -0.41
B6.A-ChrX m 20.0 0.0   8 0.0 0.0 20.0, 20.0 -0.36
B6.A-ChrY f 20.0 0.0   5 0.0 0.0 20.0, 20.0 -0.44
B6.A-ChrY m 21.2 2.5   4 1.25 0.118 20.0, 25.0 -0.29
B6.A-mt m 24.0 5.16   10 1.63 0.215 15.0, 30.0 -0.12
C57BL/6J f 19.5 4.72   11 1.42 0.241 15.0, 30.0 -0.47
C57BL/6J m 18.9 3.33   9 1.11 0.176 15.0, 25.0 -0.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 90.0 4.0737 98.0163 81.9837
A/J m 99.0 3.6436 106.17 91.83
B6.A-Chr1 f 21.6667 3.3261 28.212 15.1213
B6.A-Chr1 m 22.8571 3.0794 28.9169 16.7974
B6.A-Chr10 f 61.6667 2.1036 65.8063 57.527
B6.A-Chr10 m 44.2105 1.8691 47.8887 40.5324
B6.A-Chr11 f 35.6667 2.1036 39.8063 31.527
B6.A-Chr11 m 35.0 2.0368 39.0082 30.9918
B6.A-Chr12 f 20.0 2.8805 25.6684 14.3316
B6.A-Chr12 m 21.25 2.8805 26.9184 15.5816
B6.A-Chr13 f 25.0 5.761 36.3368 13.6632
B6.A-Chr13 m 20.0 4.7039 29.2565 10.7435
B6.A-Chr14 f 23.3333 4.7039 32.5898 14.0769
B6.A-Chr14 m 21.4286 3.0794 27.4884 15.3688
B6.A-Chr15 f 23.3333 3.3261 29.8787 16.788
B6.A-Chr15 m 20.625 2.8805 26.2934 14.9566
B6.A-Chr16 f 21.1111 2.7158 26.4553 15.7669
B6.A-Chr16 m 20.0 4.0737 28.0163 11.9837
B6.A-Chr17 f 27.5 3.3261 34.0453 20.9547
B6.A-Chr17 m 21.7857 2.1775 26.0706 17.5008
B6.A-Chr18 f 21.25 2.8805 26.9184 15.5816
B6.A-Chr18 m 20.0 4.0737 28.0163 11.9837
B6.A-Chr19 f 25.0 4.0737 33.0163 16.9837
B6.A-Chr19 m 25.0 3.3261 31.5453 18.4547
B6.A-Chr2 f 20.0 3.0794 26.0598 13.9402
B6.A-Chr2 m 20.0 3.0794 26.0598 13.9402
B6.A-Chr3 f 27.3077 2.2597 31.7544 22.861
B6.A-Chr3 m 20.0 2.8805 25.6684 14.3316
B6.A-Chr4 f 22.0 3.6436 29.17 14.83
B6.A-Chr4 m 20.0 3.3261 26.5453 13.4547
B6.A-Chr5 f 17.5 5.761 28.8368 6.1632
B6.A-Chr5 m 20.0 3.6436 27.17 12.83
B6.A-Chr6 f 20.0 3.3261 26.5453 13.4547
B6.A-Chr6 m 23.75 4.0737 31.7663 15.7337
B6.A-Chr7 f 20.0 2.5764 25.07 14.93
B6.A-Chr7 m 20.0 2.8805 25.6684 14.3316
B6.A-Chr8 f 20.0 4.7039 29.2565 10.7435
B6.A-Chr8 m 21.8182 2.4565 26.6522 16.9841
B6.A-Chr9 f 23.3333 2.7158 28.6776 17.9891
B6.A-Chr9 m 22.5 2.5764 27.57 17.43
B6.A-ChrX f 20.5 2.5764 25.57 15.43
B6.A-ChrX m 20.0 2.8805 25.6684 14.3316
B6.A-ChrY f 20.0 3.6436 27.17 12.83
B6.A-ChrY m 21.25 4.0737 29.2663 13.2337
C57BL/6J f 19.5455 2.4565 24.3795 14.7114
C57BL/6J m 18.8889 2.7158 24.2331 13.5447


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 94.5 2.7327 99.8775 89.1225
B6.A-Chr1 both 22.2619 2.2664 26.7218 17.802
B6.A-Chr10 both 52.9386 1.407 55.7074 50.1698
B6.A-Chr11 both 35.3333 1.4641 38.2144 32.4523
B6.A-Chr12 both 20.625 2.0368 24.6332 16.6168
B6.A-Chr13 both 22.5 3.7187 29.8179 15.1821
B6.A-Chr14 both 22.381 2.8111 27.9128 16.8491
B6.A-Chr15 both 21.9792 2.2 26.3085 17.6498
B6.A-Chr16 both 20.5556 2.448 25.3728 15.7383
B6.A-Chr17 both 24.6429 1.9877 28.5544 20.7313
B6.A-Chr18 both 20.625 2.4946 25.534 15.716
B6.A-Chr19 both 25.0 2.6295 30.1745 19.8255
B6.A-Chr2 both 20.0 2.1775 24.2849 15.7151
B6.A-Chr3 both 23.6538 1.8305 27.2561 20.0516
B6.A-Chr4 both 21.0 2.4667 25.8541 16.1459
B6.A-Chr5 both 18.75 3.4083 25.457 12.043
B6.A-Chr6 both 21.875 2.6295 27.0495 16.7005
B6.A-Chr7 both 20.0 1.9323 23.8025 16.1975
B6.A-Chr8 both 20.9091 2.6533 26.1304 15.6877
B6.A-Chr9 both 22.9167 1.8717 26.5999 19.2334
B6.A-ChrX both 20.25 1.9323 24.0525 16.4475
B6.A-ChrY both 20.625 2.7327 26.0025 15.2475
C57BL/6J both 19.2172 1.831 22.8203 15.6141




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA