Project measure / variable:   Johnson3   ABR_click

ID, description, units MPD:42501   ABR_click   auditory brainstem response (ABR) threshold, sound pressure level   [dB]  click stimulus  
Data set, strains Johnson3   B6.A consomic w/par   24 strains     sex: both     age: 23-30wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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Johnson3 - auditory brainstem response (ABR) threshold, sound pressure level click stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains24 strains
Mean of the strain means42.1   dB 42.2   dB
Median of the strain means40.6   dB 40.0   dB
SD of the strain means± 5.98 ± 7.45
Coefficient of variation (CV)0.142 0.176
Min–max range of strain means37.0   –   67.5   dB 36.7   –   75.0   dB
Mean sample size per strain7.1   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.5786 1.5786 0.0586 0.8089
strain 22 10572.1082 480.5504 17.8403 < 0.0001
sex:strain 22 445.789 20.2631 0.7523 0.7829
Residuals 302 8134.7626 26.9363


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 67.5 5.0   4 2.5 0.0741 60.0, 70.0 4.25
A/J m 75.0 7.07   5 3.16 0.0943 70.0, 85.0 4.4
B6.A-Chr1 f 41.7 4.08   6 1.67 0.098 40.0, 50.0 -0.07
B6.A-Chr1 m 41.4 3.78   7 1.43 0.0912 40.0, 50.0 -0.11
B6.A-Chr10 f 45.3 5.5   15 1.42 0.121 40.0, 55.0 0.54
B6.A-Chr10 m 44.7 5.89   19 1.35 0.132 40.0, 60.0 0.33
B6.A-Chr11 f 46.7 10.3   15 2.66 0.221 40.0, 70.0 0.77
B6.A-Chr11 m 48.8 10.1   16 2.52 0.207 40.0, 70.0 0.88
B6.A-Chr12 f 37.5 3.78   8 1.34 0.101 30.0, 40.0 -0.77
B6.A-Chr12 m 39.4 1.77   8 0.625 0.0449 35.0, 40.0 -0.38
B6.A-Chr13 f 40.0 0.0   2   0.0 0.0 40.0, 40.0 -0.35
B6.A-Chr13 m 40.0 0.0   3 0.0 0.0 40.0, 40.0 -0.3
B6.A-Chr14 f 41.7 2.89   3 1.67 0.0693 40.0, 45.0 -0.07
B6.A-Chr14 m 38.6 2.44   7 0.922 0.0633 35.0, 40.0 -0.49
B6.A-Chr15 f 40.8 2.04   6 0.833 0.05 40.0, 45.0 -0.22
B6.A-Chr15 m 40.6 1.77   8 0.625 0.0435 40.0, 45.0 -0.22
B6.A-Chr16 f 40.6 1.67   9 0.556 0.0411 40.0, 45.0 -0.25
B6.A-Chr16 m 40.0 0.0   4 0.0 0.0 40.0, 40.0 -0.3
B6.A-Chr17 f 43.3 5.16   6 2.11 0.119 40.0, 50.0 0.2
B6.A-Chr17 m 42.5 3.8   14 1.01 0.0894 40.0, 50.0 0.04
B6.A-Chr18 f 41.2 3.54   8 1.25 0.0857 40.0, 50.0 -0.15
B6.A-Chr18 m 45.0 5.77   4 2.89 0.128 40.0, 50.0 0.37
B6.A-Chr19 f 40.0 0.0   4 0.0 0.0 40.0, 40.0 -0.35
B6.A-Chr19 m 42.5 4.18   6 1.71 0.0984 40.0, 50.0 0.04
B6.A-Chr2 f 40.0 0.0   7 0.0 0.0 40.0, 40.0 -0.35
B6.A-Chr2 m 40.0 0.0   7 0.0 0.0 40.0, 40.0 -0.3
B6.A-Chr3 f 44.2 12.2   13 3.39 0.276 30.0, 80.0 0.35
B6.A-Chr3 m 39.4 1.77   8 0.625 0.0449 35.0, 40.0 -0.38
B6.A-Chr4 f 37.0 4.47   5 2.0 0.121 30.0, 40.0 -0.85
B6.A-Chr4 m 39.2 2.04   6 0.833 0.0521 35.0, 40.0 -0.41
B6.A-Chr5 f 40.0 0.0   2   0.0 0.0 40.0, 40.0 -0.35
B6.A-Chr5 m 40.0 0.0   5 0.0 0.0 40.0, 40.0 -0.3
B6.A-Chr6 f 41.7 4.08   6 1.67 0.098 40.0, 50.0 -0.07
B6.A-Chr6 m 40.0 0.0   4 0.0 0.0 40.0, 40.0 -0.3
B6.A-Chr7 f 41.0 3.16   10 1.0 0.0771 40.0, 50.0 -0.18
B6.A-Chr7 m 38.8 3.54   8 1.25 0.0912 30.0, 40.0 -0.46
B6.A-Chr8 f 40.0 0.0   3 0.0 0.0 40.0, 40.0 -0.35
B6.A-Chr8 m 40.5 1.51   11 0.455 0.0373 40.0, 45.0 -0.23
B6.A-Chr9 f 39.4 1.67   9 0.556 0.0423 35.0, 40.0 -0.45
B6.A-Chr9 m 40.0 0.0   10 0.0 0.0 40.0, 40.0 -0.3
B6.A-ChrX f 40.0 0.0   10 0.0 0.0 40.0, 40.0 -0.35
B6.A-ChrX m 40.0 0.0   8 0.0 0.0 40.0, 40.0 -0.3
B6.A-ChrY f 40.0 0.0   5 0.0 0.0 40.0, 40.0 -0.35
B6.A-ChrY m 37.5 5.0   4 2.5 0.133 30.0, 40.0 -0.64
B6.A-mt m 43.0 3.5   10 1.11 0.0813 40.0, 50.0 0.1
C57BL/6J f 38.6 5.52   11 1.66 0.143 30.0, 45.0 -0.58
C57BL/6J m 36.7 5.0   9 1.67 0.136 30.0, 45.0 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 67.5 2.595 72.6066 62.3934
A/J m 75.0 2.321 79.5675 70.4325
B6.A-Chr1 f 41.6667 2.1188 45.8362 37.4972
B6.A-Chr1 m 41.4286 1.9616 45.2888 37.5684
B6.A-Chr10 f 45.3333 1.3401 47.9704 42.6963
B6.A-Chr10 m 44.7368 1.1907 47.0799 42.3938
B6.A-Chr11 f 46.6667 1.3401 49.3037 44.0296
B6.A-Chr11 m 48.75 1.2975 51.3033 46.1967
B6.A-Chr12 f 37.5 1.8349 41.1109 33.8891
B6.A-Chr12 m 39.375 1.8349 42.9859 35.7641
B6.A-Chr13 f 40.0 3.6699 47.2218 32.7782
B6.A-Chr13 m 40.0 2.9965 45.8966 34.1034
B6.A-Chr14 f 41.6667 2.9965 47.5632 35.7701
B6.A-Chr14 m 38.5714 1.9616 42.4316 34.7112
B6.A-Chr15 f 40.8333 2.1188 45.0028 36.6638
B6.A-Chr15 m 40.625 1.8349 44.2359 37.0141
B6.A-Chr16 f 40.5556 1.73 43.9599 37.1512
B6.A-Chr16 m 40.0 2.595 45.1066 34.8934
B6.A-Chr17 f 43.3333 2.1188 47.5028 39.1638
B6.A-Chr17 m 42.5 1.3871 45.2296 39.7704
B6.A-Chr18 f 41.25 1.8349 44.8609 37.6391
B6.A-Chr18 m 45.0 2.595 50.1066 39.8934
B6.A-Chr19 f 40.0 2.595 45.1066 34.8934
B6.A-Chr19 m 42.5 2.1188 46.6695 38.3305
B6.A-Chr2 f 40.0 1.9616 43.8602 36.1398
B6.A-Chr2 m 40.0 1.9616 43.8602 36.1398
B6.A-Chr3 f 44.2308 1.4395 47.0634 41.3981
B6.A-Chr3 m 39.375 1.8349 42.9859 35.7641
B6.A-Chr4 f 37.0 2.321 41.5675 32.4325
B6.A-Chr4 m 39.1667 2.1188 43.3362 34.9972
B6.A-Chr5 f 40.0 3.6699 47.2218 32.7782
B6.A-Chr5 m 40.0 2.321 44.5675 35.4325
B6.A-Chr6 f 41.6667 2.1188 45.8362 37.4972
B6.A-Chr6 m 40.0 2.595 45.1066 34.8934
B6.A-Chr7 f 41.0 1.6412 44.2297 37.7703
B6.A-Chr7 m 38.75 1.8349 42.3609 35.1391
B6.A-Chr8 f 40.0 2.9965 45.8966 34.1034
B6.A-Chr8 m 40.4545 1.5648 43.5339 37.3752
B6.A-Chr9 f 39.4444 1.73 42.8488 36.0401
B6.A-Chr9 m 40.0 1.6412 43.2297 36.7703
B6.A-ChrX f 40.0 1.6412 43.2297 36.7703
B6.A-ChrX m 40.0 1.8349 43.6109 36.3891
B6.A-ChrY f 40.0 2.321 44.5675 35.4325
B6.A-ChrY m 37.5 2.595 42.6066 32.3934
C57BL/6J f 38.6364 1.5648 41.7158 35.557
C57BL/6J m 36.6667 1.73 40.0711 33.2623


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 71.25 1.7408 74.6756 67.8244
B6.A-Chr1 both 41.5476 1.4437 44.3887 38.7066
B6.A-Chr10 both 45.0351 0.8963 46.7989 43.2713
B6.A-Chr11 both 47.7083 0.9326 49.5436 45.873
B6.A-Chr12 both 38.4375 1.2975 40.9908 35.8842
B6.A-Chr13 both 40.0 2.3689 44.6617 35.3383
B6.A-Chr14 both 40.119 1.7907 43.6429 36.5952
B6.A-Chr15 both 40.7292 1.4015 43.487 37.9713
B6.A-Chr16 both 40.2778 1.5594 43.3465 37.2091
B6.A-Chr17 both 42.9167 1.2662 45.4084 40.4249
B6.A-Chr18 both 43.125 1.5891 46.2521 39.9979
B6.A-Chr19 both 41.25 1.6751 44.5463 37.9537
B6.A-Chr2 both 40.0 1.3871 42.7296 37.2704
B6.A-Chr3 both 41.8029 1.1661 44.0976 39.5082
B6.A-Chr4 both 38.0833 1.5714 41.1755 34.9911
B6.A-Chr5 both 40.0 2.1711 44.2725 35.7275
B6.A-Chr6 both 40.8333 1.6751 44.1296 37.537
B6.A-Chr7 both 39.875 1.2309 42.2973 37.4527
B6.A-Chr8 both 40.2273 1.6902 43.5534 36.9012
B6.A-Chr9 both 39.7222 1.1923 42.0685 37.3759
B6.A-ChrX both 40.0 1.2309 42.4223 37.5777
B6.A-ChrY both 38.75 1.7408 42.1756 35.3244
C57BL/6J both 37.6515 1.1664 39.9468 35.3563




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA