Project measure / variable:   Donahue9   TBIL

ID, description, units MPD:41801   TBIL   total bilirubin (plasma TBIL)   [mg/dL]  
Data set, strains Donahue9   B6.PWD consomic w/par   25 strains     sex: both     age: 11wks
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  STRAIN COMPARISON PLOT
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Donahue9 - total bilirubin (plasma TBIL)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains25 strains
Mean of the strain means0.625   mg/dL 0.695   mg/dL
Median of the strain means0.584   mg/dL 0.677   mg/dL
SD of the strain means± 0.110 ± 0.167
Coefficient of variation (CV)0.175 0.240
Min–max range of strain means0.489   –   0.853   mg/dL 0.400   –   1.04   mg/dL
Mean sample size per strain8.3   mice 8.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.4184 0.4184 7.3525 0.007
strain 22 4.912 0.2233 3.9233 < 0.0001
sex:strain 22 2.6516 0.1205 2.1179 0.0027
Residuals 333 18.9507 0.0569


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 0.506 0.137   8 0.0484 0.27 0.3, 0.66 -1.09
B6.PWD-Chr1 m 0.75 0.489   8 0.173 0.652 0.15, 1.73 0.33
B6.PWD-Chr10.1 f 0.853 0.316   8 0.112 0.371 0.45, 1.32 2.08
B6.PWD-Chr10.1 m 0.501 0.447   7 0.169 0.892 0.1, 1.42 -1.16
B6.PWD-Chr10.2 f 0.509 0.224   11 0.0676 0.44 0.17, 0.8 -1.06
B6.PWD-Chr10.2 m 0.541 0.12   10 0.0381 0.223 0.38, 0.78 -0.92
B6.PWD-Chr10.3 f 0.564 0.192   8 0.0677 0.34 0.39, 0.94 -0.56
B6.PWD-Chr10.3 m 0.4 0.216   8 0.0764 0.54 0.1, 0.66 -1.77
B6.PWD-Chr11.1 f 0.489 0.138   12 0.0399 0.283 0.25, 0.7 -1.24
B6.PWD-Chr11.1 m 0.502 0.142   12 0.041 0.283 0.29, 0.74 -1.16
B6.PWD-Chr11.2 f 0.551 0.276   10 0.0873 0.501 0.11, 0.96 -0.67
B6.PWD-Chr11.2 m 0.732 0.26   10 0.0822 0.355 0.36, 1.13 0.22
B6.PWD-Chr11.3 f 0.564 0.19   10 0.0602 0.337 0.1, 0.8 -0.56
B6.PWD-Chr11.3 m 0.677 0.404   8 0.143 0.597 0.31, 1.5 -0.11
B6.PWD-Chr12 f 0.846 0.195   8 0.0689 0.23 0.56, 1.18 2.02
B6.PWD-Chr12 m 0.916 0.278   8 0.0982 0.303 0.52, 1.37 1.33
B6.PWD-Chr14 f 0.53 0.187   9 0.0622 0.352 0.34, 0.93 -0.87
B6.PWD-Chr14 m 0.624 0.262   9 0.0874 0.42 0.24, 1.07 -0.43
B6.PWD-Chr15 f 0.584 0.202   8 0.0714 0.346 0.37, 1.0 -0.37
B6.PWD-Chr15 m 0.634 0.354   8 0.125 0.559 0.4, 1.39 -0.37
B6.PWD-Chr16 f 0.561 0.173   10 0.0547 0.309 0.29, 0.78 -0.58
B6.PWD-Chr16 m 0.87 0.213   6 0.0869 0.245 0.62, 1.12 1.05
B6.PWD-Chr17 f 0.671 0.13   8 0.0458 0.193 0.38, 0.79 0.42
B6.PWD-Chr17 m 0.472 0.136   8 0.048 0.287 0.35, 0.75 -1.34
B6.PWD-Chr18 f 0.554 0.182   8 0.0645 0.329 0.27, 0.72 -0.65
B6.PWD-Chr18 m 0.61 0.194   8 0.0685 0.318 0.39, 0.93 -0.51
B6.PWD-Chr19 f 0.699 0.18   8 0.0637 0.258 0.48, 1.01 0.68
B6.PWD-Chr19 m 0.767 0.303   8 0.107 0.395 0.5, 1.4 0.43
B6.PWD-Chr3 m 0.759 0.306   9 0.102 0.404 0.37, 1.41 0.38
B6.PWD-Chr5 f 0.595 0.175   8 0.0619 0.294 0.3, 0.82 -0.27
B6.PWD-Chr5 m 0.573 0.209   8 0.0738 0.365 0.23, 0.93 -0.73
B6.PWD-Chr6 f 0.562 0.163   8 0.0577 0.29 0.28, 0.75 -0.57
B6.PWD-Chr6 m 0.644 0.167   8 0.0592 0.26 0.46, 0.91 -0.31
B6.PWD-Chr9 f 0.59 0.2   4 0.0999 0.339 0.4, 0.87 -0.32
B6.PWD-Chr9 m 0.54 0.135   7 0.0512 0.251 0.41, 0.81 -0.93
B6.PWD-ChrX.1 f 0.658 0.197   5 0.0882 0.3 0.46, 0.98 0.3
B6.PWD-ChrX.1 m 0.64 0.211   6 0.0862 0.33 0.45, 1.04 -0.33
B6.PWD-ChrX.2 m 0.784 0.288   9 0.0959 0.367 0.4, 1.23 0.53
B6.PWD-ChrX.3 f 0.771 0.266   8 0.0942 0.345 0.44, 1.11 1.33
B6.PWD-ChrX.3 m 0.699 0.176   8 0.0622 0.252 0.49, 0.95 0.02
B6.PWD-ChrY f 0.729 0.185   8 0.0654 0.254 0.44, 0.99 0.95
B6.PWD-ChrY m 0.777 0.496   8 0.175 0.637 0.44, 1.95 0.49
B6.PWD-mt f 0.556 0.173   8 0.0611 0.311 0.34, 0.81 -0.63
B6.PWD-mt m 0.994 0.213   8 0.0752 0.214 0.68, 1.3 1.8
C57BL/6J f 0.806 0.12   8 0.0426 0.149 0.56, 0.97 1.65
C57BL/6J m 1.04 0.234   8 0.0828 0.226 0.7, 1.45 2.07
PWD/PhJ f 0.625 0.145   8 0.0511 0.231 0.5, 0.91 0.0
PWD/PhJ m 0.927 0.27   9 0.0899 0.291 0.58, 1.47 1.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 0.5062 0.0843 0.6722 0.3403
B6.PWD-Chr1 m 0.75 0.0843 0.9159 0.5841
B6.PWD-Chr10.1 f 0.8525 0.0843 1.0184 0.6866
B6.PWD-Chr10.1 m 0.5014 0.0902 0.6788 0.3241
B6.PWD-Chr10.2 f 0.5091 0.0719 0.6506 0.3676
B6.PWD-Chr10.2 m 0.541 0.0754 0.6894 0.3926
B6.PWD-Chr10.3 f 0.5637 0.0843 0.7297 0.3978
B6.PWD-Chr10.3 m 0.4 0.0843 0.5659 0.2341
B6.PWD-Chr11.1 f 0.4892 0.0689 0.6246 0.3537
B6.PWD-Chr11.1 m 0.5017 0.0689 0.6371 0.3662
B6.PWD-Chr11.2 f 0.551 0.0754 0.6994 0.4026
B6.PWD-Chr11.2 m 0.732 0.0754 0.8804 0.5836
B6.PWD-Chr11.3 f 0.564 0.0754 0.7124 0.4156
B6.PWD-Chr11.3 m 0.6775 0.0843 0.8434 0.5116
B6.PWD-Chr12 f 0.8462 0.0843 1.0122 0.6803
B6.PWD-Chr12 m 0.9163 0.0843 1.0822 0.7503
B6.PWD-Chr14 f 0.53 0.0795 0.6864 0.3736
B6.PWD-Chr14 m 0.6244 0.0795 0.7809 0.468
B6.PWD-Chr15 f 0.5837 0.0843 0.7497 0.4178
B6.PWD-Chr15 m 0.6338 0.0843 0.7997 0.4678
B6.PWD-Chr16 f 0.561 0.0754 0.7094 0.4126
B6.PWD-Chr16 m 0.87 0.0974 1.0616 0.6784
B6.PWD-Chr17 f 0.6712 0.0843 0.8372 0.5053
B6.PWD-Chr17 m 0.4725 0.0843 0.6384 0.3066
B6.PWD-Chr18 f 0.5538 0.0843 0.7197 0.3878
B6.PWD-Chr18 m 0.61 0.0843 0.7759 0.4441
B6.PWD-Chr19 f 0.6988 0.0843 0.8647 0.5328
B6.PWD-Chr19 m 0.7675 0.0843 0.9334 0.6016
B6.PWD-Chr5 f 0.595 0.0843 0.7609 0.4291
B6.PWD-Chr5 m 0.5725 0.0843 0.7384 0.4066
B6.PWD-Chr6 f 0.5625 0.0843 0.7284 0.3966
B6.PWD-Chr6 m 0.6438 0.0843 0.8097 0.4778
B6.PWD-Chr9 f 0.59 0.1193 0.8246 0.3554
B6.PWD-Chr9 m 0.54 0.0902 0.7174 0.3626
B6.PWD-ChrX.1 f 0.658 0.1067 0.8679 0.4481
B6.PWD-ChrX.1 m 0.64 0.0974 0.8316 0.4484
B6.PWD-ChrX.3 f 0.7712 0.0843 0.9372 0.6053
B6.PWD-ChrX.3 m 0.6988 0.0843 0.8647 0.5328
B6.PWD-ChrY f 0.7287 0.0843 0.8947 0.5628
B6.PWD-ChrY m 0.7775 0.0843 0.9434 0.6116
B6.PWD-mt f 0.5562 0.0843 0.7222 0.3903
B6.PWD-mt m 0.9938 0.0843 1.1597 0.8278
C57BL/6J f 0.8062 0.0843 0.9722 0.6403
C57BL/6J m 1.0363 0.0843 1.2022 0.8703
PWD/PhJ f 0.625 0.0843 0.7909 0.4591
PWD/PhJ m 0.9267 0.0795 1.0831 0.7702


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 0.6281 0.0596 0.7454 0.5108
B6.PWD-Chr10.1 both 0.677 0.0617 0.7984 0.5555
B6.PWD-Chr10.2 both 0.525 0.0521 0.6276 0.4225
B6.PWD-Chr10.3 both 0.4819 0.0596 0.5992 0.3646
B6.PWD-Chr11.1 both 0.4954 0.0487 0.5912 0.3996
B6.PWD-Chr11.2 both 0.6415 0.0533 0.7464 0.5366
B6.PWD-Chr11.3 both 0.6207 0.0566 0.732 0.5095
B6.PWD-Chr12 both 0.8813 0.0596 0.9986 0.7639
B6.PWD-Chr14 both 0.5772 0.0562 0.6878 0.4666
B6.PWD-Chr15 both 0.6088 0.0596 0.7261 0.4914
B6.PWD-Chr16 both 0.7155 0.0616 0.8367 0.5943
B6.PWD-Chr17 both 0.5719 0.0596 0.6892 0.4546
B6.PWD-Chr18 both 0.5819 0.0596 0.6992 0.4646
B6.PWD-Chr19 both 0.7331 0.0596 0.8504 0.6158
B6.PWD-Chr5 both 0.5838 0.0596 0.7011 0.4664
B6.PWD-Chr6 both 0.6031 0.0596 0.7204 0.4858
B6.PWD-Chr9 both 0.565 0.0748 0.7121 0.4179
B6.PWD-ChrX.1 both 0.649 0.0722 0.7911 0.5069
B6.PWD-ChrX.3 both 0.735 0.0596 0.8523 0.6177
B6.PWD-ChrY both 0.7531 0.0596 0.8704 0.6358
B6.PWD-mt both 0.775 0.0596 0.8923 0.6577
C57BL/6J both 0.9212 0.0596 1.0386 0.8039
PWD/PhJ both 0.7758 0.058 0.8898 0.6618




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA