Project measure / variable:   Donahue8   IgM

ID, description, units MPD:41703   IgM   immunoglobulin M (plasma IgM)   [µg/mL]  
Data set, strains Donahue8   B6.PWD consomic w/par   28 strains     sex: both     age: 9wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Donahue8 - immunoglobulin M (plasma IgM)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means180   µg/mL 167   µg/mL
Median of the strain means157   µg/mL 143   µg/mL
SD of the strain means± 95.8 ± 76.5
Coefficient of variation (CV)0.533 0.457
Min–max range of strain means70.5   –   498   µg/mL 80.8   –   445   µg/mL
Mean sample size per strain8.0   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 18765.4525 18765.4525 1.718 0.1907
strain 27 2765745.6365 102435.0236 9.3782 < 0.0001
sex:strain 27 473042.2507 17520.0834 1.604 0.0303
Residuals 387 4227054.8878 10922.6224


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 295.0 273.0   8 96.6 0.927 99.1, 777.0 1.21
B6.PWD-Chr1 m 89.1 11.9   8 4.22 0.134 70.4, 102.0 -1.02
B6.PWD-Chr10.1 f 233.0 89.3   8 31.6 0.383 110.0, 352.0 0.56
B6.PWD-Chr10.1 m 263.0 173.0   8 61.2 0.657 93.7, 647.0 1.25
B6.PWD-Chr10.2 f 195.0 145.0   8 51.3 0.746 116.0, 548.0 0.16
B6.PWD-Chr10.2 m 215.0 117.0   8 41.5 0.546 115.0, 411.0 0.62
B6.PWD-Chr10.3 f 91.8 13.6   8 4.8 0.148 79.8, 121.0 -0.92
B6.PWD-Chr10.3 m 120.0 44.3   8 15.6 0.369 86.7, 224.0 -0.62
B6.PWD-Chr11.1 f 147.0 38.9   8 13.8 0.264 107.0, 207.0 -0.34
B6.PWD-Chr11.1 m 188.0 25.7   8 9.08 0.137 148.0, 217.0 0.27
B6.PWD-Chr11.2 f 380.0 99.9   8 35.3 0.263 218.0, 511.0 2.09
B6.PWD-Chr11.2 m 264.0 133.0   8 46.9 0.502 1.27
B6.PWD-Chr11.3 f 498.0 174.0   8 61.6 0.349 278.0, 765.0 3.33
B6.PWD-Chr11.3 m 445.0 272.0   8 96.2 0.611 178.0, 848.0 3.63
B6.PWD-Chr12 f 94.5 15.2   8 5.39 0.161 70.4, 109.0 -0.89
B6.PWD-Chr12 m 96.5 7.22   8 2.55 0.0749 86.2, 109.0 -0.93
B6.PWD-Chr13 f 204.0 73.4   8 26.0 0.36 114.0, 287.0 0.26
B6.PWD-Chr13 m 202.0 122.0   8 43.2 0.604 89.6, 442.0 0.45
B6.PWD-Chr14 f 190.0 190.0   8 67.2 0.998 44.8, 553.0 0.11
B6.PWD-Chr14 m 108.0 62.9   8 22.3 0.582 63.4, 208.0 -0.78
B6.PWD-Chr15 f 134.0 26.9   8 9.53 0.2 88.3, 166.0 -0.48
B6.PWD-Chr15 m 127.0 66.5   8 23.5 0.523 40.6, 259.0 -0.53
B6.PWD-Chr16 f 147.0 90.5   8 32.0 0.616 80.8, 315.0 -0.34
B6.PWD-Chr16 m 130.0 44.8   8 15.8 0.345 79.6, 207.0 -0.49
B6.PWD-Chr17 f 84.1 16.4   8 5.8 0.195 63.0, 109.0 -1.0
B6.PWD-Chr17 m 121.0 76.1   8 26.9 0.628 -0.61
B6.PWD-Chr18 f 122.0 36.2   8 12.8 0.297 81.9, 183.0 -0.6
B6.PWD-Chr18 m 125.0 83.2   8 29.4 0.666 72.3, 327.0 -0.55
B6.PWD-Chr19 f 165.0 57.6   8 20.4 0.35 105.0, 284.0 -0.15
B6.PWD-Chr19 m 182.0 23.6   8 8.36 0.13 158.0, 232.0 0.19
B6.PWD-Chr2 f 117.0 25.1   8 8.86 0.214 83.8, 147.0 -0.65
B6.PWD-Chr2 m 143.0 31.8   8 11.3 0.222 115.0, 198.0 -0.32
B6.PWD-Chr3 f 161.0 82.3   8 29.1 0.511 91.5, 334.0 -0.19
B6.PWD-Chr3 m 187.0 45.8   8 16.2 0.244 155.0, 263.0 0.26
B6.PWD-Chr5 f 162.0 159.0   8 56.1 0.983 89.5, 553.0 -0.18
B6.PWD-Chr5 m 116.0 127.0   8 45.0 1.1 44.8, 428.0 -0.67
B6.PWD-Chr6 f 139.0 55.9   8 19.8 0.401 72.0, 208.0 -0.42
B6.PWD-Chr6 m 116.0 20.6   8 7.27 0.178 90.4, 145.0 -0.67
B6.PWD-Chr8 f 125.0 48.9   5 21.9 0.39 72.5, 206.0 -0.57
B6.PWD-Chr8 m 171.0 81.3   6 33.2 0.475 76.9, 283.0 0.05
B6.PWD-Chr9 f 70.5 16.5   8 5.84 0.234 49.1, 105.0 -1.14
B6.PWD-Chr9 m 80.8 14.1   8 5.0 0.175 61.4, 99.1 -1.13
B6.PWD-ChrX.1 f 204.0 128.0   8 45.4 0.628 125.0, 501.0 0.26
B6.PWD-ChrX.1 m 120.0 41.9   8 14.8 0.349 64.6, 193.0 -0.62
B6.PWD-ChrX.2 f 135.0 25.4   8 8.99 0.189 102.0, 176.0 -0.47
B6.PWD-ChrX.2 m 274.0 74.7   8 26.4 0.272 173.0, 374.0 1.4
B6.PWD-ChrX.3 f 160.0 59.4   8 21.0 0.372 84.8, 290.0 -0.2
B6.PWD-ChrX.3 m 174.0 108.0   8 38.3 0.623 108.0, 439.0 0.09
B6.PWD-ChrY f 333.0 292.0   8 103.0 0.876 102.0, 1004.0 1.6
B6.PWD-ChrY m 208.0 79.3   8 28.0 0.381 128.0, 379.0 0.53
B6.PWD-mt f 199.0 152.0   8 53.9 0.766 0.2
B6.PWD-mt m 143.0 39.8   8 14.1 0.278 68.5, 189.0 -0.32
C57BL/6J f 154.0 77.9   8 27.5 0.507 74.0, 305.0 -0.27
C57BL/6J m 175.0 32.1   8 11.4 0.183 134.0, 234.0 0.1
PWD/PhJ f 87.4 24.7   8 8.75 0.283 60.3, 143.0 -0.96
PWD/PhJ m 100.0 15.1   8 5.35 0.15 83.2, 126.0 -0.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 295.0 36.9503 367.6485 222.3515
B6.PWD-Chr1 m 89.1 36.9503 161.7485 16.4515
B6.PWD-Chr10.1 f 233.4375 36.9503 306.086 160.789
B6.PWD-Chr10.1 m 263.4125 36.9503 336.061 190.764
B6.PWD-Chr10.2 f 194.5875 36.9503 267.236 121.939
B6.PWD-Chr10.2 m 214.75 36.9503 287.3985 142.1015
B6.PWD-Chr10.3 f 91.75 36.9503 164.3985 19.1015
B6.PWD-Chr10.3 m 119.85 36.9503 192.4985 47.2015
B6.PWD-Chr11.1 f 147.4625 36.9503 220.111 74.814
B6.PWD-Chr11.1 m 187.9625 36.9503 260.611 115.314
B6.PWD-Chr11.2 f 380.2625 36.9503 452.911 307.614
B6.PWD-Chr11.2 m 264.175 36.9503 336.8235 191.5265
B6.PWD-Chr11.3 f 498.325 36.9503 570.9735 425.6765
B6.PWD-Chr11.3 m 445.275 36.9503 517.9235 372.6265
B6.PWD-Chr12 f 94.45 36.9503 167.0985 21.8015
B6.PWD-Chr12 m 96.4625 36.9503 169.111 23.814
B6.PWD-Chr13 f 204.225 36.9503 276.8735 131.5765
B6.PWD-Chr13 m 202.2625 36.9503 274.911 129.614
B6.PWD-Chr14 f 190.3875 36.9503 263.036 117.739
B6.PWD-Chr14 m 108.1875 36.9503 180.836 35.539
B6.PWD-Chr15 f 134.4 36.9503 207.0485 61.7515
B6.PWD-Chr15 m 127.0 36.9503 199.6485 54.3515
B6.PWD-Chr16 f 146.8625 36.9503 219.511 74.214
B6.PWD-Chr16 m 129.8375 36.9503 202.486 57.189
B6.PWD-Chr17 f 84.1125 36.9503 156.761 11.464
B6.PWD-Chr17 m 121.275 36.9503 193.9235 48.6265
B6.PWD-Chr18 f 122.1375 36.9503 194.786 49.489
B6.PWD-Chr18 m 124.8625 36.9503 197.511 52.214
B6.PWD-Chr19 f 164.7375 36.9503 237.386 92.089
B6.PWD-Chr19 m 182.025 36.9503 254.6735 109.3765
B6.PWD-Chr2 f 117.3 36.9503 189.9485 44.6515
B6.PWD-Chr2 m 143.2875 36.9503 215.936 70.639
B6.PWD-Chr3 f 161.2375 36.9503 233.886 88.589
B6.PWD-Chr3 m 187.3625 36.9503 260.011 114.714
B6.PWD-Chr5 f 161.5375 36.9503 234.186 88.889
B6.PWD-Chr5 m 116.0875 36.9503 188.736 43.439
B6.PWD-Chr6 f 139.2875 36.9503 211.936 66.639
B6.PWD-Chr6 m 115.6375 36.9503 188.286 42.989
B6.PWD-Chr8 f 125.46 46.7389 217.3539 33.5661
B6.PWD-Chr8 m 171.3167 42.6666 255.204 87.4294
B6.PWD-Chr9 f 70.4625 36.9503 143.111 0.0
B6.PWD-Chr9 m 80.85 36.9503 153.4985 8.2015
B6.PWD-ChrX.1 f 204.3875 36.9503 277.036 131.739
B6.PWD-ChrX.1 m 120.2625 36.9503 192.911 47.614
B6.PWD-ChrX.2 f 134.5625 36.9503 207.211 61.914
B6.PWD-ChrX.2 m 274.275 36.9503 346.9235 201.6265
B6.PWD-ChrX.3 f 159.875 36.9503 232.5235 87.2265
B6.PWD-ChrX.3 m 173.7 36.9503 246.3485 101.0515
B6.PWD-ChrY f 333.025 36.9503 405.6735 260.3765
B6.PWD-ChrY m 208.175 36.9503 280.8235 135.5265
B6.PWD-mt f 199.0875 36.9503 271.736 126.439
B6.PWD-mt m 143.2625 36.9503 215.911 70.614
C57BL/6J f 153.675 36.9503 226.3235 81.0265
C57BL/6J m 175.4375 36.9503 248.086 102.789
PWD/PhJ f 87.45 36.9503 160.0985 14.8015
PWD/PhJ m 100.5 36.9503 173.1485 27.8515


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 192.05 26.1278 243.4203 140.6797
B6.PWD-Chr10.1 both 248.425 26.1278 299.7953 197.0547
B6.PWD-Chr10.2 both 204.6688 26.1278 256.039 153.2985
B6.PWD-Chr10.3 both 105.8 26.1278 157.1703 54.4297
B6.PWD-Chr11.1 both 167.7125 26.1278 219.0828 116.3422
B6.PWD-Chr11.2 both 322.2188 26.1278 373.589 270.8485
B6.PWD-Chr11.3 both 471.8 26.1278 523.1703 420.4297
B6.PWD-Chr12 both 95.4562 26.1278 146.8265 44.086
B6.PWD-Chr13 both 203.2438 26.1278 254.614 151.8735
B6.PWD-Chr14 both 149.2875 26.1278 200.6578 97.9172
B6.PWD-Chr15 both 130.7 26.1278 182.0703 79.3297
B6.PWD-Chr16 both 138.35 26.1278 189.7203 86.9797
B6.PWD-Chr17 both 102.6937 26.1278 154.064 51.3235
B6.PWD-Chr18 both 123.5 26.1278 174.8703 72.1297
B6.PWD-Chr19 both 173.3812 26.1278 224.7515 122.011
B6.PWD-Chr2 both 130.2938 26.1278 181.664 78.9235
B6.PWD-Chr3 both 174.3 26.1278 225.6703 122.9297
B6.PWD-Chr5 both 138.8125 26.1278 190.1828 87.4422
B6.PWD-Chr6 both 127.4625 26.1278 178.8328 76.0922
B6.PWD-Chr8 both 148.3883 31.6424 210.6008 86.1758
B6.PWD-Chr9 both 75.6563 26.1278 127.0265 24.286
B6.PWD-ChrX.1 both 162.325 26.1278 213.6953 110.9547
B6.PWD-ChrX.2 both 204.4188 26.1278 255.789 153.0485
B6.PWD-ChrX.3 both 166.7875 26.1278 218.1578 115.4172
B6.PWD-ChrY both 270.6 26.1278 321.9703 219.2297
B6.PWD-mt both 171.175 26.1278 222.5453 119.8047
C57BL/6J both 164.5563 26.1278 215.9265 113.186
PWD/PhJ both 93.975 26.1278 145.3453 42.6047




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA