Phenotype measure

ID, description, units MPD:41702   IgG   immunoglobulin G (plasma IgG)   [µg/mL]
Data set, strains Donahue8   B6.PWD consomic w/par   28 strains     sex: both     age: 9wks
Procedure immunoglobulin quantification
Ontology mappings


  STRAIN COMPARISON PLOT
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Donahue8 - immunoglobulin G (plasma IgG)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means156   µg/mL 113   µg/mL
Median of the strain means160   µg/mL 104   µg/mL
SD of the strain means± 81.3 ± 59.1
Coefficient of variation (CV)0.520 0.522
Min–max range of strain means9.75   –   371   µg/mL 12.4   –   253   µg/mL
Mean sample size per strain8.0   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 210712.8163 210712.8163 60.3907 < 0.0001
strain 27 1977885.2901 73255.0107 20.995 < 0.0001
sex:strain 27 201340.4502 7457.0537 2.1372 0.001
Residuals 387 1350304.2588 3489.1583


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 313.0 105.0   8 37.3 0.337 124.0, 467.0 1.93
B6.PWD-Chr1 m 253.0 82.7   8 29.3 0.327 150.0, 419.0 2.36
B6.PWD-Chr10.1 f 160.0 25.9   8 9.15 0.162 118.0, 188.0 0.05
B6.PWD-Chr10.1 m 80.9 35.0   8 12.4 0.433 40.7, 132.0 -0.55
B6.PWD-Chr10.2 f 161.0 66.9   8 23.6 0.416 76.7, 287.0 0.06
B6.PWD-Chr10.2 m 120.0 62.4   8 22.1 0.521 48.3, 253.0 0.11
B6.PWD-Chr10.3 f 211.0 54.3   8 19.2 0.257 153.0, 306.0 0.67
B6.PWD-Chr10.3 m 130.0 46.4   8 16.4 0.356 56.9, 190.0 0.28
B6.PWD-Chr11.1 f 80.9 20.0   8 7.08 0.248 54.8, 111.0 -0.93
B6.PWD-Chr11.1 m 47.9 10.5   8 3.7 0.219 35.0, 66.2 -1.1
B6.PWD-Chr11.2 f 95.6 34.6   8 12.2 0.362 64.6, 153.0 -0.75
B6.PWD-Chr11.2 m 60.9 34.3   8 12.1 0.563 0.0, 107.0 -0.88
B6.PWD-Chr11.3 f 279.0 37.7   8 13.3 0.135 219.0, 328.0 1.51
B6.PWD-Chr11.3 m 185.0 86.4   8 30.6 0.467 85.2, 345.0 1.21
B6.PWD-Chr12 f 54.5 18.6   8 6.58 0.341 23.7, 88.6 -1.25
B6.PWD-Chr12 m 44.7 13.9   8 4.92 0.311 26.1, 66.5 -1.16
B6.PWD-Chr13 f 191.0 124.0   8 43.8 0.648 65.4, 408.0 0.43
B6.PWD-Chr13 m 99.0 41.0   8 14.5 0.415 49.1, 186.0 -0.24
B6.PWD-Chr14 f 123.0 53.7   8 19.0 0.438 49.5, 186.0 -0.41
B6.PWD-Chr14 m 105.0 35.8   8 12.6 0.34 70.9, 165.0 -0.14
B6.PWD-Chr15 f 141.0 58.9   8 20.8 0.418 56.5, 228.0 -0.19
B6.PWD-Chr15 m 95.0 34.2   8 12.1 0.36 42.5, 148.0 -0.31
B6.PWD-Chr16 f 76.4 30.6   8 10.8 0.401 16.5, 116.0 -0.98
B6.PWD-Chr16 m 59.3 27.6   8 9.77 0.466 20.1, 91.0 -0.91
B6.PWD-Chr17 f 185.0 50.5   8 17.9 0.274 62.5, 216.0 0.35
B6.PWD-Chr17 m 102.0 66.3   8 23.4 0.648 0.0, 202.0 -0.19
B6.PWD-Chr18 f 204.0 87.3   8 30.9 0.428 104.0, 378.0 0.59
B6.PWD-Chr18 m 176.0 87.7   8 31.0 0.499 119.0, 389.0 1.06
B6.PWD-Chr19 f 162.0 49.7   8 17.6 0.307 89.2, 235.0 0.07
B6.PWD-Chr19 m 96.1 49.2   8 17.4 0.512 32.8, 182.0 -0.29
B6.PWD-Chr2 f 39.8 27.4   8 9.69 0.69 13.9, 85.2 -1.43
B6.PWD-Chr2 m 33.1 24.3   8 8.59 0.734 13.4, 85.9 -1.36
B6.PWD-Chr3 f 81.7 20.4   8 7.2 0.249 48.4, 107.0 -0.92
B6.PWD-Chr3 m 72.3 28.3   8 10.0 0.392 36.7, 120.0 -0.69
B6.PWD-Chr5 f 371.0 101.0   8 35.9 0.274 234.0, 510.0 2.64
B6.PWD-Chr5 m 187.0 107.0   8 37.8 0.57 0.0, 320.0 1.25
B6.PWD-Chr6 f 207.0 78.7   8 27.8 0.38 110.0, 326.0 0.62
B6.PWD-Chr6 m 221.0 71.8   8 25.4 0.324 139.0, 365.0 1.82
B6.PWD-Chr8 f 126.0 18.6   5 8.3 0.148 105.0, 147.0 -0.37
B6.PWD-Chr8 m 134.0 91.4   6 37.3 0.681 46.2, 310.0 0.35
B6.PWD-Chr9 f 62.9 28.7   8 10.2 0.457 32.3, 120.0 -1.15
B6.PWD-Chr9 m 61.3 29.9   8 10.6 0.487 29.1, 121.0 -0.88
B6.PWD-ChrX.1 f 160.0 69.1   8 24.4 0.432 93.0, 320.0 0.05
B6.PWD-ChrX.1 m 67.6 34.4   8 12.2 0.51 28.9, 127.0 -0.77
B6.PWD-ChrX.2 f 146.0 61.9   8 21.9 0.425 59.8, 233.0 -0.13
B6.PWD-ChrX.2 m 163.0 48.9   8 17.3 0.3 96.9, 233.0 0.84
B6.PWD-ChrX.3 f 162.0 51.8   8 18.3 0.319 72.7, 216.0 0.07
B6.PWD-ChrX.3 m 111.0 34.2   8 12.1 0.308 78.6, 171.0 -0.04
B6.PWD-ChrY f 190.0 80.4   8 28.4 0.424 97.3, 289.0 0.41
B6.PWD-ChrY m 141.0 58.0   8 20.5 0.412 63.7, 234.0 0.47
B6.PWD-mt f 215.0 129.0   8 45.5 0.598 0.0, 421.0 0.72
B6.PWD-mt m 182.0 48.5   8 17.1 0.266 121.0, 247.0 1.16
C57BL/6J f 169.0 50.3   8 17.8 0.298 110.0, 241.0 0.16
C57BL/6J m 130.0 40.8   8 14.4 0.313 74.6, 204.0 0.28
PWD/PhJ f 9.75 3.5   8 1.24 0.359 3.2, 13.4 -1.8
PWD/PhJ m 12.4 10.5   8 3.73 0.853 0.0, 29.2 -1.71


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 312.9875 20.8841 354.048 271.927
B6.PWD-Chr1 m 253.2625 20.8841 294.323 212.202
B6.PWD-Chr10.1 f 159.8 20.8841 200.8605 118.7395
B6.PWD-Chr10.1 m 80.8625 20.8841 121.923 39.802
B6.PWD-Chr10.2 f 160.6375 20.8841 201.698 119.577
B6.PWD-Chr10.2 m 119.6625 20.8841 160.723 78.602
B6.PWD-Chr10.3 f 211.475 20.8841 252.5355 170.4145
B6.PWD-Chr10.3 m 130.2125 20.8841 171.273 89.152
B6.PWD-Chr11.1 f 80.8875 20.8841 121.948 39.827
B6.PWD-Chr11.1 m 47.9375 20.8841 88.998 6.877
B6.PWD-Chr11.2 f 95.55 20.8841 136.6105 54.4895
B6.PWD-Chr11.2 m 60.8875 20.8841 101.948 19.827
B6.PWD-Chr11.3 f 279.2375 20.8841 320.298 238.177
B6.PWD-Chr11.3 m 185.0875 20.8841 226.148 144.027
B6.PWD-Chr12 f 54.5 20.8841 95.5605 13.4395
B6.PWD-Chr12 m 44.7 20.8841 85.7605 3.6395
B6.PWD-Chr13 f 191.05 20.8841 232.1105 149.9895
B6.PWD-Chr13 m 99.0125 20.8841 140.073 57.952
B6.PWD-Chr14 f 122.6875 20.8841 163.748 81.627
B6.PWD-Chr14 m 105.2375 20.8841 146.298 64.177
B6.PWD-Chr15 f 140.875 20.8841 181.9355 99.8145
B6.PWD-Chr15 m 94.9875 20.8841 136.048 53.927
B6.PWD-Chr16 f 76.375 20.8841 117.4355 35.3145
B6.PWD-Chr16 m 59.325 20.8841 100.3855 18.2645
B6.PWD-Chr17 f 184.6 20.8841 225.6605 143.5395
B6.PWD-Chr17 m 102.4 20.8841 143.4605 61.3395
B6.PWD-Chr18 f 203.925 20.8841 244.9855 162.8645
B6.PWD-Chr18 m 175.6875 20.8841 216.748 134.627
B6.PWD-Chr19 f 162.0625 20.8841 203.123 121.002
B6.PWD-Chr19 m 96.075 20.8841 137.1355 55.0145
B6.PWD-Chr2 f 39.75 20.8841 80.8105 0.0
B6.PWD-Chr2 m 33.075 20.8841 74.1355 0.0
B6.PWD-Chr3 f 81.7375 20.8841 122.798 40.677
B6.PWD-Chr3 m 72.3375 20.8841 113.398 31.277
B6.PWD-Chr5 f 370.7625 20.8841 411.823 329.702
B6.PWD-Chr5 m 187.3375 20.8841 228.398 146.277
B6.PWD-Chr6 f 206.8 20.8841 247.8605 165.7395
B6.PWD-Chr6 m 221.2875 20.8841 262.348 180.227
B6.PWD-Chr8 f 125.52 26.4165 177.4578 73.5822
B6.PWD-Chr8 m 134.1167 24.1149 181.5292 86.7041
B6.PWD-Chr9 f 62.8625 20.8841 103.923 21.802
B6.PWD-Chr9 m 61.275 20.8841 102.3355 20.2145
B6.PWD-ChrX.1 f 159.9375 20.8841 200.998 118.877
B6.PWD-ChrX.1 m 67.575 20.8841 108.6355 26.5145
B6.PWD-ChrX.2 f 145.6 20.8841 186.6605 104.5395
B6.PWD-ChrX.2 m 163.05 20.8841 204.1105 121.9895
B6.PWD-ChrX.3 f 162.3625 20.8841 203.423 121.302
B6.PWD-ChrX.3 m 110.9375 20.8841 151.998 69.877
B6.PWD-ChrY f 189.7875 20.8841 230.848 148.727
B6.PWD-ChrY m 140.5875 20.8841 181.648 99.527
B6.PWD-mt f 215.2 20.8841 256.2605 174.1395
B6.PWD-mt m 181.8875 20.8841 222.948 140.827
C57BL/6J f 169.075 20.8841 210.1355 128.0145
C57BL/6J m 130.25 20.8841 171.3105 89.1895
PWD/PhJ f 9.75 20.8841 50.8105 0.0
PWD/PhJ m 12.3625 20.8841 53.423 0.0


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 283.125 14.7673 312.1591 254.0909
B6.PWD-Chr10.1 both 120.3313 14.7673 149.3654 91.2971
B6.PWD-Chr10.2 both 140.15 14.7673 169.1841 111.1159
B6.PWD-Chr10.3 both 170.8438 14.7673 199.8779 141.8096
B6.PWD-Chr11.1 both 64.4125 14.7673 93.4466 35.3784
B6.PWD-Chr11.2 both 78.2187 14.7673 107.2529 49.1846
B6.PWD-Chr11.3 both 232.1625 14.7673 261.1966 203.1284
B6.PWD-Chr12 both 49.6 14.7673 78.6341 20.5659
B6.PWD-Chr13 both 145.0313 14.7673 174.0654 115.9971
B6.PWD-Chr14 both 113.9625 14.7673 142.9966 84.9284
B6.PWD-Chr15 both 117.9313 14.7673 146.9654 88.8971
B6.PWD-Chr16 both 67.85 14.7673 96.8841 38.8159
B6.PWD-Chr17 both 143.5 14.7673 172.5341 114.4659
B6.PWD-Chr18 both 189.8063 14.7673 218.8404 160.7721
B6.PWD-Chr19 both 129.0687 14.7673 158.1029 100.0346
B6.PWD-Chr2 both 36.4125 14.7673 65.4466 7.3784
B6.PWD-Chr3 both 77.0375 14.7673 106.0716 48.0034
B6.PWD-Chr5 both 279.05 14.7673 308.0841 250.0159
B6.PWD-Chr6 both 214.0437 14.7673 243.0779 185.0096
B6.PWD-Chr8 both 129.8183 17.8841 164.9804 94.6563
B6.PWD-Chr9 both 62.0688 14.7673 91.1029 33.0346
B6.PWD-ChrX.1 both 113.7562 14.7673 142.7904 84.7221
B6.PWD-ChrX.2 both 154.325 14.7673 183.3591 125.2909
B6.PWD-ChrX.3 both 136.65 14.7673 165.6841 107.6159
B6.PWD-ChrY both 165.1875 14.7673 194.2216 136.1534
B6.PWD-mt both 198.5438 14.7673 227.5779 169.5096
C57BL/6J both 149.6625 14.7673 178.6966 120.6284
PWD/PhJ both 11.0562 14.7673 40.0904 0.0