Project measure / variable:   Donahue8   IgA

ID, description, units MPD:41701   IgA   immunoglobulin A (plasma IgA)   [µg/mL]  
Data set, strains Donahue8   B6.PWD consomic w/par   28 strains     sex: both     age: 9wks
Procedure immunoglobulin quantification
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  STRAIN COMPARISON PLOT
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Donahue8 - immunoglobulin A (plasma IgA)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means8.65   µg/mL 8.76   µg/mL
Median of the strain means7.94   µg/mL 7.68   µg/mL
SD of the strain means± 3.11 ± 3.77
Coefficient of variation (CV)0.359 0.430
Min–max range of strain means3.39   –   16.9   µg/mL 4.22   –   20.7   µg/mL
Mean sample size per strain8.0   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3928 0.3928 0.0576 0.8104
strain 27 4521.5072 167.4632 24.5727 < 0.0001
sex:strain 27 602.6135 22.319 3.275 < 0.0001
Residuals 387 2637.4067 6.815


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 14.7 4.36   8 1.54 0.296 8.6, 21.0 1.95
B6.PWD-Chr1 m 14.9 4.0   8 1.42 0.269 11.4, 23.8 1.63
B6.PWD-Chr10.1 f 9.12 2.67   8 0.943 0.292 5.5, 13.1 0.15
B6.PWD-Chr10.1 m 7.22 2.54   8 0.899 0.352 5.0, 13.0 -0.41
B6.PWD-Chr10.2 f 8.07 1.19   8 0.422 0.148 7.1, 10.7 -0.19
B6.PWD-Chr10.2 m 7.3 1.35   8 0.477 0.185 5.3, 9.4 -0.39
B6.PWD-Chr10.3 f 6.82 0.641   8 0.227 0.0939 6.0, 7.5 -0.59
B6.PWD-Chr10.3 m 5.25 0.907   8 0.321 0.173 4.0, 6.9 -0.93
B6.PWD-Chr11.1 f 8.8 2.71   8 0.96 0.308 5.3, 13.0 0.05
B6.PWD-Chr11.1 m 11.1 3.43   8 1.21 0.309 6.8, 17.6 0.62
B6.PWD-Chr11.2 f 12.5 2.04   8 0.722 0.163 9.1, 15.1 1.24
B6.PWD-Chr11.2 m 9.59 4.17   8 1.47 0.435 0.22
B6.PWD-Chr11.3 f 11.5 1.44   8 0.507 0.125 9.3, 13.2 0.92
B6.PWD-Chr11.3 m 14.3 2.95   8 1.04 0.206 9.5, 19.1 1.47
B6.PWD-Chr12 f 16.9 1.38   8 0.488 0.0816 15.2, 19.1 2.65
B6.PWD-Chr12 m 20.7 3.96   8 1.4 0.191 15.5, 25.5 3.17
B6.PWD-Chr13 f 9.2 2.35   8 0.832 0.256 6.2, 13.6 0.18
B6.PWD-Chr13 m 8.86 2.09   8 0.738 0.236 5.9, 11.6 0.03
B6.PWD-Chr14 f 13.7 2.8   8 0.991 0.205 9.6, 18.0 1.62
B6.PWD-Chr14 m 11.7 2.43   8 0.857 0.207 9.4, 16.9 0.78
B6.PWD-Chr15 f 6.83 2.27   8 0.802 0.333 4.0, 10.8 -0.59
B6.PWD-Chr15 m 6.31 2.25   8 0.794 0.356 4.9, 11.3 -0.65
B6.PWD-Chr16 f 6.0 1.81   8 0.639 0.301 4.5, 10.1 -0.85
B6.PWD-Chr16 m 4.61 2.13   8 0.754 0.463 -1.1
B6.PWD-Chr17 f 6.67 1.77   8 0.627 0.266 4.2, 9.3 -0.64
B6.PWD-Chr17 m 8.14 4.9   8 1.73 0.602 -0.16
B6.PWD-Chr18 f 7.21 3.48   8 1.23 0.483 3.8, 14.5 -0.46
B6.PWD-Chr18 m 6.39 2.71   8 0.959 0.425 4.0, 12.7 -0.63
B6.PWD-Chr19 f 8.71 3.13   8 1.11 0.359 5.7, 15.1 0.02
B6.PWD-Chr19 m 6.71 2.08   8 0.736 0.31 2.7, 9.3 -0.54
B6.PWD-Chr2 f 3.39 1.24   8 0.438 0.365 2.0, 5.3 -1.69
B6.PWD-Chr2 m 4.24 2.5   8 0.883 0.589 1.4, 7.5 -1.2
B6.PWD-Chr3 f 6.83 1.26   8 0.447 0.185 4.5, 8.4 -0.59
B6.PWD-Chr3 m 6.04 1.18   8 0.417 0.195 4.5, 8.4 -0.72
B6.PWD-Chr5 f 7.49 1.54   8 0.545 0.206 5.5, 9.6 -0.37
B6.PWD-Chr5 m 6.24 2.81   8 0.993 0.45 -0.67
B6.PWD-Chr6 f 10.3 2.78   8 0.982 0.27 6.1, 13.9 0.53
B6.PWD-Chr6 m 6.94 1.22   8 0.43 0.175 5.9, 9.4 -0.48
B6.PWD-Chr8 f 6.32 1.21   5 0.542 0.192 4.4, 7.6 -0.75
B6.PWD-Chr8 m 10.8 3.33   6 1.36 0.308 6.5, 15.3 0.54
B6.PWD-Chr9 f 8.78 1.67   8 0.592 0.191 7.2, 12.5 0.04
B6.PWD-Chr9 m 9.11 1.06   8 0.374 0.116 7.7, 10.8 0.09
B6.PWD-ChrX.1 f 5.31 1.91   8 0.676 0.36 3.7, 9.8 -1.07
B6.PWD-ChrX.1 m 4.22 1.04   8 0.366 0.245 2.8, 5.8 -1.21
B6.PWD-ChrX.2 f 5.94 1.53   8 0.542 0.258 3.3, 8.5 -0.87
B6.PWD-ChrX.2 m 11.8 3.64   8 1.29 0.309 7.8, 18.7 0.81
B6.PWD-ChrX.3 f 6.84 2.49   8 0.88 0.364 4.4, 11.7 -0.58
B6.PWD-ChrX.3 m 6.46 1.52   8 0.537 0.235 4.3, 9.1 -0.61
B6.PWD-ChrY f 12.3 3.58   8 1.26 0.292 9.3, 19.0 1.17
B6.PWD-ChrY m 9.95 2.01   8 0.71 0.202 6.8, 12.9 0.32
B6.PWD-mt f 8.85 5.46   8 1.93 0.617 0.06
B6.PWD-mt m 8.06 2.29   8 0.811 0.284 3.5, 10.2 -0.19
C57BL/6J f 7.81 1.34   8 0.475 0.172 6.0, 9.9 -0.27
C57BL/6J m 12.9 5.13   8 1.81 0.398 8.7, 21.4 1.1
PWD/PhJ f 5.32 0.266   8 0.094 0.0499 4.9, 5.7 -1.07
PWD/PhJ m 5.42 0.678   8 0.24 0.125 4.3, 6.3 -0.89


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 14.7375 0.923 16.5522 12.9228
B6.PWD-Chr1 m 14.875 0.923 16.6897 13.0603
B6.PWD-Chr10.1 f 9.125 0.923 10.9397 7.3103
B6.PWD-Chr10.1 m 7.225 0.923 9.0397 5.4103
B6.PWD-Chr10.2 f 8.075 0.923 9.8897 6.2603
B6.PWD-Chr10.2 m 7.3 0.923 9.1147 5.4853
B6.PWD-Chr10.3 f 6.825 0.923 8.6397 5.0103
B6.PWD-Chr10.3 m 5.25 0.923 7.0647 3.4353
B6.PWD-Chr11.1 f 8.8 0.923 10.6147 6.9853
B6.PWD-Chr11.1 m 11.1 0.923 12.9147 9.2853
B6.PWD-Chr11.2 f 12.5125 0.923 14.3272 10.6978
B6.PWD-Chr11.2 m 9.5875 0.923 11.4022 7.7728
B6.PWD-Chr11.3 f 11.45 0.923 13.2647 9.6353
B6.PWD-Chr11.3 m 14.2875 0.923 16.1022 12.4728
B6.PWD-Chr12 f 16.925 0.923 18.7397 15.1103
B6.PWD-Chr12 m 20.7125 0.923 22.5272 18.8978
B6.PWD-Chr13 f 9.2 0.923 11.0147 7.3853
B6.PWD-Chr13 m 8.8625 0.923 10.6772 7.0478
B6.PWD-Chr14 f 13.6625 0.923 15.4772 11.8478
B6.PWD-Chr14 m 11.7125 0.923 13.5272 9.8978
B6.PWD-Chr15 f 6.825 0.923 8.6397 5.0103
B6.PWD-Chr15 m 6.3125 0.923 8.1272 4.4978
B6.PWD-Chr16 f 6.0 0.923 7.8147 4.1853
B6.PWD-Chr16 m 4.6125 0.923 6.4272 2.7978
B6.PWD-Chr17 f 6.675 0.923 8.4897 4.8603
B6.PWD-Chr17 m 8.1375 0.923 9.9522 6.3228
B6.PWD-Chr18 f 7.2125 0.923 9.0272 5.3978
B6.PWD-Chr18 m 6.3875 0.923 8.2022 4.5728
B6.PWD-Chr19 f 8.7125 0.923 10.5272 6.8978
B6.PWD-Chr19 m 6.7125 0.923 8.5272 4.8978
B6.PWD-Chr2 f 3.3875 0.923 5.2022 1.5728
B6.PWD-Chr2 m 4.2375 0.923 6.0522 2.4228
B6.PWD-Chr3 f 6.825 0.923 8.6397 5.0103
B6.PWD-Chr3 m 6.0375 0.923 7.8522 4.2228
B6.PWD-Chr5 f 7.4875 0.923 9.3022 5.6728
B6.PWD-Chr5 m 6.2375 0.923 8.0522 4.4228
B6.PWD-Chr6 f 10.2875 0.923 12.1022 8.4728
B6.PWD-Chr6 m 6.9375 0.923 8.7522 5.1228
B6.PWD-Chr8 f 6.32 1.1675 8.6154 4.0246
B6.PWD-Chr8 m 10.8 1.0658 12.8954 8.7046
B6.PWD-Chr9 f 8.775 0.923 10.5897 6.9603
B6.PWD-Chr9 m 9.1125 0.923 10.9272 7.2978
B6.PWD-ChrX.1 f 5.3125 0.923 7.1272 3.4978
B6.PWD-ChrX.1 m 4.225 0.923 6.0397 2.4103
B6.PWD-ChrX.2 f 5.9375 0.923 7.7522 4.1228
B6.PWD-ChrX.2 m 11.775 0.923 13.5897 9.9603
B6.PWD-ChrX.3 f 6.8375 0.923 8.6522 5.0228
B6.PWD-ChrX.3 m 6.4625 0.923 8.2772 4.6478
B6.PWD-ChrY f 12.25 0.923 14.0647 10.4353
B6.PWD-ChrY m 9.95 0.923 11.7647 8.1353
B6.PWD-mt f 8.85 0.923 10.6647 7.0353
B6.PWD-mt m 8.0625 0.923 9.8772 6.2478
C57BL/6J f 7.8125 0.923 9.6272 5.9978
C57BL/6J m 12.875 0.923 14.6897 11.0603
PWD/PhJ f 5.325 0.923 7.1397 3.5103
PWD/PhJ m 5.425 0.923 7.2397 3.6103


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 14.8063 0.6526 16.0894 13.5231
B6.PWD-Chr10.1 both 8.175 0.6526 9.4582 6.8918
B6.PWD-Chr10.2 both 7.6875 0.6526 8.9707 6.4043
B6.PWD-Chr10.3 both 6.0375 0.6526 7.3207 4.7543
B6.PWD-Chr11.1 both 9.95 0.6526 11.2332 8.6668
B6.PWD-Chr11.2 both 11.05 0.6526 12.3332 9.7668
B6.PWD-Chr11.3 both 12.8688 0.6526 14.1519 11.5856
B6.PWD-Chr12 both 18.8187 0.6526 20.1019 17.5356
B6.PWD-Chr13 both 9.0313 0.6526 10.3144 7.7481
B6.PWD-Chr14 both 12.6875 0.6526 13.9707 11.4043
B6.PWD-Chr15 both 6.5688 0.6526 7.8519 5.2856
B6.PWD-Chr16 both 5.3063 0.6526 6.5894 4.0231
B6.PWD-Chr17 both 7.4063 0.6526 8.6894 6.1231
B6.PWD-Chr18 both 6.8 0.6526 8.0832 5.5168
B6.PWD-Chr19 both 7.7125 0.6526 8.9957 6.4293
B6.PWD-Chr2 both 3.8125 0.6526 5.0957 2.5293
B6.PWD-Chr3 both 6.4313 0.6526 7.7144 5.1481
B6.PWD-Chr5 both 6.8625 0.6526 8.1457 5.5793
B6.PWD-Chr6 both 8.6125 0.6526 9.8957 7.3293
B6.PWD-Chr8 both 8.56 0.7904 10.114 7.006
B6.PWD-Chr9 both 8.9438 0.6526 10.2269 7.6606
B6.PWD-ChrX.1 both 4.7688 0.6526 6.0519 3.4856
B6.PWD-ChrX.2 both 8.8563 0.6526 10.1394 7.5731
B6.PWD-ChrX.3 both 6.65 0.6526 7.9332 5.3668
B6.PWD-ChrY both 11.1 0.6526 12.3832 9.8168
B6.PWD-mt both 8.4563 0.6526 9.7394 7.1731
C57BL/6J both 10.3438 0.6526 11.6269 9.0606
PWD/PhJ both 5.375 0.6526 6.6582 4.0918




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA