Phenotype measure:   Donahue6   pct_CD4

ID, description, units MPD:41510   pct_CD4   CD4 T cells (percentage of viable WBC)   [%]
Data set, strains Donahue6   B6.PWD consomic w/par   28 strains     sex: both     age: 7wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue6 - CD4 T cells (percentage of viable WBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means11.6   % 11.1   %
Median of the strain means10.8   % 10.9   %
SD of the strain means± 4.57 ± 3.87
Coefficient of variation (CV)0.394 0.350
Min–max range of strain means5.12   –   26.8   % 3.10   –   22.9   %
Mean sample size per strain8.3   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 21.5091 21.5091 2.0719 0.1508
strain 27 6446.0234 238.7416 22.9966 < 0.0001
sex:strain 27 974.2919 36.0849 3.4759 < 0.0001
Residuals 419 4349.8851 10.3816


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 11.3 2.19   8 0.776 0.194 8.53, 14.1 -0.06
B6.PWD-Chr1 m 13.1 2.72   8 0.961 0.208 9.95, 17.0 0.53
B6.PWD-Chr10.1 f 12.0 4.94   11 1.49 0.412 4.57, 19.0 0.09
B6.PWD-Chr10.1 m 13.1 5.43   8 1.92 0.414 2.93, 19.1 0.53
B6.PWD-Chr10.2 f 11.3 1.96   8 0.695 0.173 8.74, 14.3 -0.06
B6.PWD-Chr10.2 m 12.4 1.32   8 0.467 0.106 9.65, 13.9 0.35
B6.PWD-Chr10.3 f 10.3 2.02   8 0.715 0.196 6.13, 13.0 -0.28
B6.PWD-Chr10.3 m 11.2 3.6   8 1.27 0.321 2.71, 14.0 0.04
B6.PWD-Chr11.1 f 9.43 1.98   12 0.572 0.21 5.69, 14.1 -0.47
B6.PWD-Chr11.1 m 10.6 2.04   12 0.589 0.193 7.36, 16.0 -0.12
B6.PWD-Chr11.2 f 15.4 6.67   9 2.22 0.434 5.81, 27.3 0.83
B6.PWD-Chr11.2 m 13.8 4.21   10 1.33 0.306 11.1, 25.3 0.71
B6.PWD-Chr11.3 f 15.8 1.9   8 0.671 0.12 12.3, 18.6 0.92
B6.PWD-Chr11.3 m 16.5 1.17   10 0.369 0.0706 14.5, 18.0 1.41
B6.PWD-Chr12 f 10.7 3.89   8 1.38 0.363 5.08, 14.0 -0.2
B6.PWD-Chr12 m 11.1 4.31   8 1.52 0.388 4.9, 16.1 0.01
B6.PWD-Chr13 f 11.0 1.6   8 0.566 0.145 9.34, 14.1 -0.13
B6.PWD-Chr13 m 10.0 1.9   9 0.632 0.189 8.38, 14.8 -0.27
B6.PWD-Chr14 f 6.91 2.37   8 0.839 0.343 2.98, 10.1 -1.02
B6.PWD-Chr14 m 8.05 1.76   10 0.556 0.218 5.83, 10.7 -0.78
B6.PWD-Chr15 f 8.54 1.54   7 0.582 0.18 6.89, 11.1 -0.67
B6.PWD-Chr15 m 10.9 2.01   8 0.712 0.184 8.18, 14.1 -0.04
B6.PWD-Chr16 f 5.12 2.12   8 0.749 0.413 1.94, 7.72 -1.42
B6.PWD-Chr16 m 8.42 3.7   8 1.31 0.44 3.79, 14.7 -0.68
B6.PWD-Chr17 f 10.9 1.39   8 0.491 0.127 8.43, 12.8 -0.15
B6.PWD-Chr17 m 7.82 3.0   8 1.06 0.383 4.12, 11.4 -0.84
B6.PWD-Chr18 f 12.6 1.9   8 0.671 0.15 10.5, 15.5 0.22
B6.PWD-Chr18 m 12.8 1.82   8 0.644 0.142 9.92, 14.6 0.45
B6.PWD-Chr19 f 11.0 2.29   8 0.81 0.209 6.83, 14.6 -0.13
B6.PWD-Chr19 m 14.0 2.27   7 0.859 0.162 11.8, 18.0 0.76
B6.PWD-Chr2 f 11.1 1.5   10 0.473 0.135 9.2, 13.8 -0.11
B6.PWD-Chr2 m 10.7 2.21   8 0.781 0.206 6.66, 13.0 -0.09
B6.PWD-Chr3 f 20.0 6.16   8 2.18 0.309 9.03, 27.9 1.84
B6.PWD-Chr3 m 9.88 1.75   8 0.618 0.177 7.61, 12.1 -0.3
B6.PWD-Chr5 f 8.82 2.28   8 0.805 0.258 5.86, 11.9 -0.61
B6.PWD-Chr5 m 7.2 2.88   8 1.02 0.4 1.83, 12.0 -1.0
B6.PWD-Chr6 f 7.73 6.14   8 2.17 0.794 2.29, 17.9 -0.85
B6.PWD-Chr6 m 3.1 1.51   8 0.534 0.486 0.79, 4.91 -2.06
B6.PWD-Chr8 f 20.4 1.92   5 0.858 0.0939 17.0, 21.5 1.93
B6.PWD-Chr8 m 18.1 3.31   5 1.48 0.183 14.0, 21.2 1.82
B6.PWD-Chr9 f 8.5 4.79   8 1.69 0.564 3.96, 18.6 -0.68
B6.PWD-Chr9 m 7.46 2.98   8 1.05 0.399 3.33, 11.3 -0.93
B6.PWD-ChrX.1 f 9.47 5.72   8 2.02 0.604 3.45, 15.7 -0.46
B6.PWD-ChrX.1 m 10.9 5.13   7 1.94 0.47 3.18, 15.2 -0.04
B6.PWD-ChrX.2 f 13.2 0.812   8 0.287 0.0615 12.2, 14.7 0.35
B6.PWD-ChrX.2 m 7.03 2.17   9 0.722 0.308 4.41, 11.1 -1.04
B6.PWD-ChrX.3 f 8.04 3.79   8 1.34 0.471 3.53, 14.7 -0.78
B6.PWD-ChrX.3 m 11.0 1.75   8 0.619 0.159 8.27, 13.1 -0.01
B6.PWD-ChrY f 10.1 4.32   8 1.53 0.429 4.17, 14.8 -0.33
B6.PWD-ChrY m 8.16 4.86   8 1.72 0.595 2.78, 14.3 -0.75
B6.PWD-mt f 10.2 1.09   7 0.413 0.107 8.87, 11.3 -0.3
B6.PWD-mt m 11.3 1.5   8 0.529 0.132 9.28, 13.6 0.06
C57BL/6J f 7.94 2.72   16 0.681 0.343 3.68, 12.7 -0.8
C57BL/6J m 7.91 3.0   16 0.749 0.379 2.1, 12.3 -0.81
PWD/PhJ f 26.8 1.83   7 0.69 0.068 24.8, 30.6 3.33
PWD/PhJ m 22.9 4.92   8 1.74 0.214 13.5, 28.1 3.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 11.3075 1.1392 13.5467 9.0683
B6.PWD-Chr1 m 13.0812 1.1392 15.3204 10.8421
B6.PWD-Chr10.1 f 11.9855 0.9715 13.895 10.0759
B6.PWD-Chr10.1 m 13.1187 1.1392 15.3579 10.8796
B6.PWD-Chr10.2 f 11.3462 1.1392 13.5854 9.1071
B6.PWD-Chr10.2 m 12.4187 1.1392 14.6579 10.1796
B6.PWD-Chr10.3 f 10.32 1.1392 12.5592 8.0808
B6.PWD-Chr10.3 m 11.2138 1.1392 13.4529 8.9746
B6.PWD-Chr11.1 f 9.4258 0.9301 11.2541 7.5975
B6.PWD-Chr11.1 m 10.5958 0.9301 12.4241 8.7675
B6.PWD-Chr11.2 f 15.36 1.074 17.4711 13.2489
B6.PWD-Chr11.2 m 13.76 1.0189 15.7628 11.7572
B6.PWD-Chr11.3 f 15.8 1.1392 18.0392 13.5608
B6.PWD-Chr11.3 m 16.52 1.0189 18.5228 14.5172
B6.PWD-Chr12 f 10.7275 1.1392 12.9667 8.4883
B6.PWD-Chr12 m 11.1113 1.1392 13.3504 8.8721
B6.PWD-Chr13 f 11.0413 1.1392 13.2804 8.8021
B6.PWD-Chr13 m 10.0278 1.074 12.1389 7.9166
B6.PWD-Chr14 f 6.9113 1.1392 9.1504 4.6721
B6.PWD-Chr14 m 8.055 1.0189 10.0578 6.0522
B6.PWD-Chr15 f 8.5386 1.2178 10.9324 6.1448
B6.PWD-Chr15 m 10.9313 1.1392 13.1704 8.6921
B6.PWD-Chr16 f 5.125 1.1392 7.3642 2.8858
B6.PWD-Chr16 m 8.4188 1.1392 10.6579 6.1796
B6.PWD-Chr17 f 10.9287 1.1392 13.1679 8.6896
B6.PWD-Chr17 m 7.8175 1.1392 10.0567 5.5783
B6.PWD-Chr18 f 12.6125 1.1392 14.8517 10.3733
B6.PWD-Chr18 m 12.79 1.1392 15.0292 10.5508
B6.PWD-Chr19 f 10.9762 1.1392 13.2154 8.7371
B6.PWD-Chr19 m 14.0429 1.2178 16.4367 11.6491
B6.PWD-Chr2 f 11.069 1.0189 13.0718 9.0662
B6.PWD-Chr2 m 10.7388 1.1392 12.9779 8.4996
B6.PWD-Chr3 f 19.9662 1.1392 22.2054 17.7271
B6.PWD-Chr3 m 9.8775 1.1392 12.1167 7.6383
B6.PWD-Chr5 f 8.8188 1.1392 11.0579 6.5796
B6.PWD-Chr5 m 7.2013 1.1392 9.4404 4.9621
B6.PWD-Chr6 f 7.7313 1.1392 9.9704 5.4921
B6.PWD-Chr6 m 3.1038 1.1392 5.3429 0.8646
B6.PWD-Chr8 f 20.42 1.4409 23.2524 17.5876
B6.PWD-Chr8 m 18.08 1.4409 20.9124 15.2476
B6.PWD-Chr9 f 8.5013 1.1392 10.7404 6.2621
B6.PWD-Chr9 m 7.465 1.1392 9.7042 5.2258
B6.PWD-ChrX.1 f 9.4712 1.1392 11.7104 7.2321
B6.PWD-ChrX.1 m 10.9043 1.2178 13.2981 8.5105
B6.PWD-ChrX.2 f 13.2 1.1392 15.4392 10.9608
B6.PWD-ChrX.2 m 7.0256 1.074 9.1367 4.9144
B6.PWD-ChrX.3 f 8.045 1.1392 10.2842 5.8058
B6.PWD-ChrX.3 m 11.0437 1.1392 13.2829 8.8046
B6.PWD-ChrY f 10.0688 1.1392 12.3079 7.8296
B6.PWD-ChrY m 8.1638 1.1392 10.4029 5.9246
B6.PWD-mt f 10.19 1.2178 12.5838 7.7962
B6.PWD-mt m 11.2975 1.1392 13.5367 9.0583
C57BL/6J f 7.935 0.8055 9.5183 6.3517
C57BL/6J m 7.9087 0.8055 9.4921 6.3254
PWD/PhJ f 26.8429 1.2178 29.2367 24.4491
PWD/PhJ m 22.925 1.1392 25.1642 20.6858


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 12.1944 0.8055 13.7777 10.611
B6.PWD-Chr10.1 both 12.5521 0.7486 14.0235 11.0807
B6.PWD-Chr10.2 both 11.8825 0.8055 13.4658 10.2992
B6.PWD-Chr10.3 both 10.7669 0.8055 12.3502 9.1835
B6.PWD-Chr11.1 both 10.0108 0.6577 11.3036 8.718
B6.PWD-Chr11.2 both 14.56 0.7402 16.015 13.105
B6.PWD-Chr11.3 both 16.16 0.7642 17.6621 14.6579
B6.PWD-Chr12 both 10.9194 0.8055 12.5027 9.336
B6.PWD-Chr13 both 10.5345 0.7828 12.0733 8.9958
B6.PWD-Chr14 both 7.4831 0.7642 8.9852 5.981
B6.PWD-Chr15 both 9.7349 0.8338 11.3738 8.096
B6.PWD-Chr16 both 6.7719 0.8055 8.3552 5.1885
B6.PWD-Chr17 both 9.3731 0.8055 10.9565 7.7898
B6.PWD-Chr18 both 12.7012 0.8055 14.2846 11.1179
B6.PWD-Chr19 both 12.5096 0.8338 14.1485 10.8706
B6.PWD-Chr2 both 10.9039 0.7642 12.406 9.4018
B6.PWD-Chr3 both 14.9219 0.8055 16.5052 13.3385
B6.PWD-Chr5 both 8.01 0.8055 9.5933 6.4267
B6.PWD-Chr6 both 5.4175 0.8055 7.0008 3.8342
B6.PWD-Chr8 both 19.25 1.0189 21.2528 17.2472
B6.PWD-Chr9 both 7.9831 0.8055 9.5665 6.3998
B6.PWD-ChrX.1 both 10.1878 0.8338 11.8267 8.5488
B6.PWD-ChrX.2 both 10.1128 0.7828 11.6515 8.574
B6.PWD-ChrX.3 both 9.5444 0.8055 11.1277 7.961
B6.PWD-ChrY both 9.1163 0.8055 10.6996 7.5329
B6.PWD-mt both 10.7438 0.8338 12.3827 9.1048
C57BL/6J both 7.9219 0.5696 9.0415 6.8023
PWD/PhJ both 24.8839 0.8338 26.5228 23.245




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA