Project measure / variable:   Donahue6   pct_T_cells

ID, description, units MPD:41509   pct_T_cells   T cells (percentage of viable WBC)   [%]  
Data set, strains Donahue6   B6.PWD consomic w/par   28 strains     sex: both     age: 7wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Donahue6 - T cells (percentage of viable WBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means22.7   % 20.8   %
Median of the strain means21.5   % 20.8   %
SD of the strain means± 6.00 ± 5.54
Coefficient of variation (CV)0.265 0.266
Min–max range of strain means14.0   –   40.7   % 6.21   –   34.8   %
Mean sample size per strain8.3   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 328.1515 328.1515 13.8691 0.0002
strain 27 12824.2703 474.973 20.0744 < 0.0001
sex:strain 27 1611.0797 59.6696 2.5219 0.0001
Residuals 419 9913.7894 23.6606


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 21.9 2.23   8 0.79 0.102 18.1, 25.9 -0.13
B6.PWD-Chr1 m 23.4 3.07   8 1.09 0.131 18.2, 27.0 0.47
B6.PWD-Chr10.1 f 22.8 6.03   11 1.82 0.265 15.5, 33.4 0.02
B6.PWD-Chr10.1 m 22.4 8.04   8 2.84 0.359 11.3, 33.6 0.29
B6.PWD-Chr10.2 f 25.8 4.46   8 1.58 0.173 20.9, 31.9 0.52
B6.PWD-Chr10.2 m 22.9 3.04   8 1.07 0.133 17.4, 25.6 0.38
B6.PWD-Chr10.3 f 25.9 6.58   8 2.33 0.254 16.3, 36.7 0.54
B6.PWD-Chr10.3 m 22.2 6.89   8 2.43 0.31 5.53, 26.8 0.25
B6.PWD-Chr11.1 f 20.0 2.98   12 0.859 0.149 15.9, 25.3 -0.44
B6.PWD-Chr11.1 m 20.4 3.3   12 0.952 0.162 15.7, 27.5 -0.08
B6.PWD-Chr11.2 f 28.2 9.13   9 3.04 0.324 14.8, 44.6 0.93
B6.PWD-Chr11.2 m 27.2 6.32   10 2.0 0.232 19.1, 42.9 1.15
B6.PWD-Chr11.3 f 32.1 4.1   8 1.45 0.128 26.2, 38.7 1.58
B6.PWD-Chr11.3 m 31.3 2.35   10 0.742 0.075 27.6, 36.1 1.89
B6.PWD-Chr12 f 22.7 3.8   8 1.34 0.167 17.3, 26.5 0.01
B6.PWD-Chr12 m 22.2 4.97   8 1.76 0.224 15.0, 29.0 0.25
B6.PWD-Chr13 f 19.1 2.32   8 0.82 0.122 16.6, 23.4 -0.59
B6.PWD-Chr13 m 16.4 2.11   9 0.703 0.129 13.9, 21.5 -0.8
B6.PWD-Chr14 f 15.1 4.83   8 1.71 0.32 5.54, 19.8 -1.26
B6.PWD-Chr14 m 16.4 1.97   10 0.622 0.12 13.6, 19.9 -0.8
B6.PWD-Chr15 f 18.3 3.02   7 1.14 0.164 15.0, 23.7 -0.73
B6.PWD-Chr15 m 19.0 3.56   8 1.26 0.187 13.0, 25.0 -0.33
B6.PWD-Chr16 f 14.0 5.42   8 1.92 0.387 5.25, 20.1 -1.44
B6.PWD-Chr16 m 18.4 5.29   8 1.87 0.288 9.51, 26.2 -0.44
B6.PWD-Chr17 f 22.0 2.08   8 0.737 0.0946 17.7, 24.8 -0.11
B6.PWD-Chr17 m 16.0 6.81   8 2.41 0.426 8.21, 27.1 -0.87
B6.PWD-Chr18 f 20.5 2.94   8 1.04 0.143 17.2, 24.8 -0.36
B6.PWD-Chr18 m 20.5 2.41   8 0.851 0.117 16.6, 22.9 -0.06
B6.PWD-Chr19 f 22.8 4.07   8 1.44 0.178 15.0, 27.9 0.02
B6.PWD-Chr19 m 25.5 3.3   7 1.25 0.129 22.0, 31.0 0.84
B6.PWD-Chr2 f 18.8 2.84   10 0.899 0.151 15.5, 23.1 -0.64
B6.PWD-Chr2 m 17.4 4.19   8 1.48 0.241 9.86, 22.2 -0.62
B6.PWD-Chr3 f 34.3 7.27   8 2.57 0.212 22.9, 43.4 1.94
B6.PWD-Chr3 m 22.3 3.25   8 1.15 0.145 16.8, 26.9 0.27
B6.PWD-Chr5 f 19.9 4.58   8 1.62 0.23 14.2, 27.0 -0.46
B6.PWD-Chr5 m 15.3 5.24   8 1.85 0.342 3.68, 21.2 -1.0
B6.PWD-Chr6 f 15.9 9.78   8 3.46 0.615 5.33, 31.1 -1.13
B6.PWD-Chr6 m 6.21 2.8   8 0.989 0.451 1.77, 10.0 -2.64
B6.PWD-Chr8 f 30.8 3.92   5 1.75 0.127 24.1, 33.8 1.36
B6.PWD-Chr8 m 28.1 6.25   5 2.79 0.222 21.2, 34.6 1.31
B6.PWD-Chr9 f 20.1 7.26   8 2.57 0.36 7.42, 31.2 -0.43
B6.PWD-Chr9 m 19.1 4.87   8 1.72 0.254 9.85, 26.2 -0.31
B6.PWD-ChrX.1 f 19.2 8.45   8 2.99 0.44 7.22, 29.0 -0.58
B6.PWD-ChrX.1 m 21.1 5.82   7 2.2 0.276 12.3, 26.3 0.05
B6.PWD-ChrX.2 f 23.4 1.7   8 0.602 0.0729 21.1, 26.6 0.12
B6.PWD-ChrX.2 m 15.8 3.18   9 1.06 0.201 12.3, 20.9 -0.91
B6.PWD-ChrX.3 f 19.1 5.47   8 1.94 0.287 12.7, 28.9 -0.59
B6.PWD-ChrX.3 m 22.6 2.95   8 1.04 0.13 18.7, 26.9 0.32
B6.PWD-ChrY f 22.0 4.84   8 1.71 0.22 16.5, 27.6 -0.11
B6.PWD-ChrY m 17.6 6.0   8 2.12 0.341 10.4, 26.4 -0.58
B6.PWD-mt f 21.1 3.25   7 1.23 0.154 16.7, 25.2 -0.26
B6.PWD-mt m 21.9 1.58   8 0.558 0.0722 19.3, 24.8 0.2
C57BL/6J f 17.8 4.54   16 1.13 0.255 10.9, 25.9 -0.81
C57BL/6J m 16.5 4.28   16 1.07 0.259 7.48, 22.6 -0.78
PWD/PhJ f 40.7 2.97   7 1.12 0.0729 37.2, 46.6 3.01
PWD/PhJ m 34.8 7.14   8 2.53 0.205 20.8, 42.3 2.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 21.925 1.7198 25.3054 18.5446
B6.PWD-Chr1 m 23.3725 1.7198 26.7529 19.9921
B6.PWD-Chr10.1 f 22.7909 1.4666 25.6738 19.9081
B6.PWD-Chr10.1 m 22.3987 1.7198 25.7792 19.0183
B6.PWD-Chr10.2 f 25.7966 1.7198 29.1771 22.4162
B6.PWD-Chr10.2 m 22.8862 1.7198 26.2667 19.5058
B6.PWD-Chr10.3 f 25.8762 1.7198 29.2567 22.4958
B6.PWD-Chr10.3 m 22.2015 1.7198 25.5819 18.8211
B6.PWD-Chr11.1 f 19.9906 1.4042 22.7507 17.2305
B6.PWD-Chr11.1 m 20.408 1.4042 23.1681 17.6479
B6.PWD-Chr11.2 f 28.222 1.6214 31.4091 25.0349
B6.PWD-Chr11.2 m 27.239 1.5382 30.2626 24.2154
B6.PWD-Chr11.3 f 32.0625 1.7198 35.4429 28.6821
B6.PWD-Chr11.3 m 31.291 1.5382 34.3146 28.2674
B6.PWD-Chr12 f 22.7171 1.7198 26.0976 19.3367
B6.PWD-Chr12 m 22.2075 1.7198 25.5879 18.8271
B6.PWD-Chr13 f 19.0525 1.7198 22.4329 15.6721
B6.PWD-Chr13 m 16.3989 1.6214 19.586 13.2118
B6.PWD-Chr14 f 15.1301 1.7198 18.5106 11.7497
B6.PWD-Chr14 m 16.3714 1.5382 19.395 13.3478
B6.PWD-Chr15 f 18.349 1.8385 21.9628 14.7352
B6.PWD-Chr15 m 18.9963 1.7198 22.3767 15.6158
B6.PWD-Chr16 f 14.0003 1.7198 17.3807 10.6198
B6.PWD-Chr16 m 18.3574 1.7198 21.7378 14.9769
B6.PWD-Chr17 f 22.0425 1.7198 25.4229 18.6621
B6.PWD-Chr17 m 15.99 1.7198 19.3704 12.6096
B6.PWD-Chr18 f 20.5144 1.7198 23.8948 17.1339
B6.PWD-Chr18 m 20.488 1.7198 23.8684 17.1076
B6.PWD-Chr19 f 22.8425 1.7198 26.2229 19.4621
B6.PWD-Chr19 m 25.5229 1.8385 29.1367 21.909
B6.PWD-Chr2 f 18.764 1.5382 21.7876 15.7404
B6.PWD-Chr2 m 17.3753 1.7198 20.7557 13.9948
B6.PWD-Chr3 f 34.2812 1.7198 37.6617 30.9008
B6.PWD-Chr3 m 22.32 1.7198 25.7004 18.9396
B6.PWD-Chr5 f 19.9075 1.7198 23.2879 16.5271
B6.PWD-Chr5 m 15.3185 1.7198 18.6989 11.9381
B6.PWD-Chr6 f 15.9161 1.7198 19.2966 12.5357
B6.PWD-Chr6 m 6.2051 1.7198 9.5856 2.8247
B6.PWD-Chr8 f 30.788 2.1753 35.0639 26.5121
B6.PWD-Chr8 m 28.082 2.1753 32.3579 23.8061
B6.PWD-Chr9 f 20.1474 1.7198 23.5278 16.7669
B6.PWD-Chr9 m 19.1325 1.7198 22.5129 15.7521
B6.PWD-ChrX.1 f 19.1797 1.7198 22.5602 15.7993
B6.PWD-ChrX.1 m 21.1071 1.8385 24.721 17.4933
B6.PWD-ChrX.2 f 23.35 1.7198 26.7304 19.9696
B6.PWD-ChrX.2 m 15.8011 1.6214 18.9882 12.614
B6.PWD-ChrX.3 f 19.0613 1.7198 22.4417 15.6808
B6.PWD-ChrX.3 m 22.5887 1.7198 25.9692 19.2083
B6.PWD-ChrY f 22.0218 1.7198 25.4022 18.6413
B6.PWD-ChrY m 17.628 1.7198 21.0084 14.2476
B6.PWD-mt f 21.1394 1.8385 24.7533 17.5256
B6.PWD-mt m 21.8525 1.7198 25.2329 18.4721
C57BL/6J f 17.8031 1.2161 20.1935 15.4128
C57BL/6J m 16.5325 1.2161 18.9228 14.1422
PWD/PhJ f 40.6873 1.8385 44.3011 37.0735
PWD/PhJ m 34.8481 1.7198 38.2286 31.4677


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 22.6487 1.2161 25.0391 20.2584
B6.PWD-Chr10.1 both 22.5948 1.1301 24.8162 20.3735
B6.PWD-Chr10.2 both 24.3414 1.2161 26.7318 21.9511
B6.PWD-Chr10.3 both 24.0389 1.2161 26.4292 21.6485
B6.PWD-Chr11.1 both 20.1993 0.9929 22.151 18.2476
B6.PWD-Chr11.2 both 27.7305 1.1175 29.9271 25.5339
B6.PWD-Chr11.3 both 31.6767 1.1537 33.9444 29.4091
B6.PWD-Chr12 both 22.4623 1.2161 24.8526 20.072
B6.PWD-Chr13 both 17.7257 1.1818 20.0487 15.4027
B6.PWD-Chr14 both 15.7508 1.1537 18.0184 13.4831
B6.PWD-Chr15 both 18.6726 1.2587 21.1468 16.1984
B6.PWD-Chr16 both 16.1788 1.2161 18.5691 13.7885
B6.PWD-Chr17 both 19.0162 1.2161 21.4066 16.6259
B6.PWD-Chr18 both 20.5012 1.2161 22.8915 18.1109
B6.PWD-Chr19 both 24.1827 1.2587 26.6569 21.7085
B6.PWD-Chr2 both 18.0696 1.1537 20.3373 15.802
B6.PWD-Chr3 both 28.3006 1.2161 30.691 25.9103
B6.PWD-Chr5 both 17.613 1.2161 20.0033 15.2227
B6.PWD-Chr6 both 11.0606 1.2161 13.451 8.6703
B6.PWD-Chr8 both 29.435 1.5382 32.4586 26.4114
B6.PWD-Chr9 both 19.6399 1.2161 22.0303 17.2496
B6.PWD-ChrX.1 both 20.1434 1.2587 22.6177 17.6692
B6.PWD-ChrX.2 both 19.5756 1.1818 21.8985 17.2526
B6.PWD-ChrX.3 both 20.825 1.2161 23.2153 18.4347
B6.PWD-ChrY both 19.8249 1.2161 22.2152 17.4345
B6.PWD-mt both 21.496 1.2587 23.9702 19.0217
C57BL/6J both 17.1678 0.8599 18.858 15.4776
PWD/PhJ both 37.7677 1.2587 40.2419 35.2935




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA