Phenotype measure:   Donahue6   pct_B_cells

ID, description, units MPD:41506   pct_B_cells   B cells (percentage of viable WBC)   [%]
Data set, strains Donahue6   B6.PWD consomic w/par   28 strains     sex: both     age: 7wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue6 - B cells (percentage of viable WBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means45.9   % 44.2   %
Median of the strain means47.6   % 45.3   %
SD of the strain means± 9.72 ± 10.5
Coefficient of variation (CV)0.212 0.238
Min–max range of strain means21.4   –   58.1   % 20.5   –   61.5   %
Mean sample size per strain8.3   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 341.7982 341.7982 5.7423 0.017
strain 27 43474.2314 1610.1567 27.0512 < 0.0001
sex:strain 27 4462.2037 165.2668 2.7765 < 0.0001
Residuals 419 24939.9649 59.5226


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 40.3 4.64   8 1.64 0.115 35.1, 47.8 -0.58
B6.PWD-Chr1 m 37.7 5.62   8 1.99 0.149 28.8, 46.3 -0.62
B6.PWD-Chr10.1 f 45.1 2.85   11 0.859 0.0632 40.0, 50.0 -0.08
B6.PWD-Chr10.1 m 41.2 7.21   8 2.55 0.175 31.6, 49.9 -0.28
B6.PWD-Chr10.2 f 49.4 5.28   8 1.87 0.107 42.1, 57.8 0.36
B6.PWD-Chr10.2 m 48.6 5.5   8 1.94 0.113 43.6, 57.7 0.42
B6.PWD-Chr10.3 f 48.3 7.47   8 2.64 0.155 32.2, 59.1 0.24
B6.PWD-Chr10.3 m 45.3 12.7   8 4.5 0.281 14.3, 54.3 0.1
B6.PWD-Chr11.1 f 54.9 5.58   12 1.61 0.102 47.4, 67.7 0.92
B6.PWD-Chr11.1 m 50.1 5.96   12 1.72 0.119 40.6, 60.3 0.56
B6.PWD-Chr11.2 f 46.5 10.5   9 3.51 0.227 20.2, 55.1 0.06
B6.PWD-Chr11.2 m 39.3 4.62   10 1.46 0.117 30.1, 45.2 -0.47
B6.PWD-Chr11.3 f 41.7 4.26   8 1.51 0.102 34.1, 47.2 -0.43
B6.PWD-Chr11.3 m 41.4 6.87   10 2.17 0.166 29.5, 48.3 -0.27
B6.PWD-Chr12 f 50.6 4.51   8 1.59 0.0891 43.4, 56.4 0.48
B6.PWD-Chr12 m 47.9 6.44   8 2.28 0.135 35.3, 55.0 0.35
B6.PWD-Chr13 f 57.8 6.5   8 2.3 0.112 48.4, 66.1 1.22
B6.PWD-Chr13 m 58.6 11.2   9 3.75 0.192 31.0, 68.4 1.37
B6.PWD-Chr14 f 57.8 16.5   8 5.84 0.286 17.4, 68.1 1.22
B6.PWD-Chr14 m 61.5 4.2   10 1.33 0.0682 55.7, 67.2 1.64
B6.PWD-Chr15 f 37.7 13.9   7 5.24 0.368 25.9, 66.8 -0.85
B6.PWD-Chr15 m 52.1 12.1   8 4.27 0.232 41.5, 68.1 0.75
B6.PWD-Chr16 f 53.4 8.02   8 2.83 0.15 36.6, 61.4 0.77
B6.PWD-Chr16 m 56.3 4.89   8 1.73 0.087 49.4, 63.5 1.15
B6.PWD-Chr17 f 51.4 4.11   8 1.45 0.0799 45.1, 58.5 0.56
B6.PWD-Chr17 m 34.2 15.0   8 5.31 0.44 14.3, 55.0 -0.95
B6.PWD-Chr18 f 58.1 3.24   8 1.14 0.0556 54.2, 62.4 1.25
B6.PWD-Chr18 m 57.5 4.22   8 1.49 0.0733 50.2, 63.0 1.26
B6.PWD-Chr19 f 49.3 4.42   8 1.56 0.0896 40.3, 53.8 0.35
B6.PWD-Chr19 m 46.5 2.78   7 1.05 0.0598 42.4, 50.4 0.22
B6.PWD-Chr2 f 48.2 5.78   10 1.83 0.12 38.9, 57.6 0.23
B6.PWD-Chr2 m 38.6 6.87   8 2.43 0.178 27.0, 48.1 -0.53
B6.PWD-Chr3 f 30.9 3.48   8 1.23 0.112 23.9, 34.9 -1.54
B6.PWD-Chr3 m 24.1 6.33   8 2.24 0.263 15.9, 31.8 -1.91
B6.PWD-Chr5 f 49.6 8.07   8 2.85 0.163 34.5, 59.9 0.38
B6.PWD-Chr5 m 49.0 16.8   8 5.96 0.344 12.2, 64.9 0.46
B6.PWD-Chr6 f 21.7 3.65   8 1.29 0.168 17.3, 28.1 -2.49
B6.PWD-Chr6 m 28.9 11.7   8 4.14 0.406 5.61, 43.4 -1.45
B6.PWD-Chr8 f 44.5 5.17   5 2.31 0.116 39.9, 51.9 -0.15
B6.PWD-Chr8 m 42.4 6.44   5 2.88 0.152 34.6, 50.2 -0.17
B6.PWD-Chr9 f 46.1 15.5   8 5.48 0.336 13.7, 61.1 0.02
B6.PWD-Chr9 m 47.3 5.69   8 2.01 0.12 39.7, 53.8 0.29
B6.PWD-ChrX.1 f 46.7 13.6   8 4.81 0.291 15.4, 56.7 0.08
B6.PWD-ChrX.1 m 52.7 6.72   7 2.54 0.128 39.5, 57.1 0.81
B6.PWD-ChrX.2 f 51.9 4.41   8 1.56 0.0851 42.9, 56.6 0.61
B6.PWD-ChrX.2 m 35.6 8.0   9 2.67 0.224 27.0, 50.5 -0.82
B6.PWD-ChrX.3 f 32.6 10.4   8 3.68 0.319 20.9, 47.1 -1.37
B6.PWD-ChrX.3 m 31.1 7.79   8 2.76 0.251 20.5, 40.5 -1.24
B6.PWD-ChrY f 45.3 4.83   8 1.71 0.107 36.4, 52.0 -0.06
B6.PWD-ChrY m 45.3 3.06   8 1.08 0.0675 40.9, 50.2 0.1
B6.PWD-mt f 47.0 6.86   7 2.59 0.146 40.0, 59.7 0.11
B6.PWD-mt m 43.6 4.66   8 1.65 0.107 36.8, 50.5 -0.06
C57BL/6J f 57.6 2.39   16 0.597 0.0415 54.4, 61.9 1.2
C57BL/6J m 60.2 4.17   16 1.04 0.0693 53.1, 68.3 1.52
PWD/PhJ f 21.4 2.36   7 0.893 0.111 17.6, 24.1 -2.52
PWD/PhJ m 20.5 2.31   8 0.816 0.113 16.4, 22.9 -2.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 40.3063 2.7277 45.6679 34.9446
B6.PWD-Chr1 m 37.7 2.7277 43.0617 32.3383
B6.PWD-Chr10.1 f 45.0609 2.3262 49.6334 40.4885
B6.PWD-Chr10.1 m 41.1675 2.7277 46.5292 35.8058
B6.PWD-Chr10.2 f 49.4188 2.7277 54.7804 44.0571
B6.PWD-Chr10.2 m 48.6388 2.7277 54.0004 43.2771
B6.PWD-Chr10.3 f 48.2813 2.7277 53.6429 42.9196
B6.PWD-Chr10.3 m 45.3435 2.7277 50.7052 39.9818
B6.PWD-Chr11.1 f 54.8558 2.2272 59.2336 50.478
B6.PWD-Chr11.1 m 50.1233 2.2272 54.5011 45.7455
B6.PWD-Chr11.2 f 46.4722 2.5717 51.5273 41.4172
B6.PWD-Chr11.2 m 39.334 2.4397 44.1296 34.5384
B6.PWD-Chr11.3 f 41.6588 2.7277 47.0204 36.2971
B6.PWD-Chr11.3 m 41.393 2.4397 46.1886 36.5974
B6.PWD-Chr12 f 50.5962 2.7277 55.9579 45.2346
B6.PWD-Chr12 m 47.9025 2.7277 53.2642 42.5408
B6.PWD-Chr13 f 57.785 2.7277 63.1467 52.4233
B6.PWD-Chr13 m 58.6378 2.5717 63.6928 53.5827
B6.PWD-Chr14 f 57.7512 2.7277 63.1129 52.3896
B6.PWD-Chr14 m 61.516 2.4397 66.3116 56.7204
B6.PWD-Chr15 f 37.6586 2.916 43.3904 31.9267
B6.PWD-Chr15 m 52.1225 2.7277 57.4842 46.7608
B6.PWD-Chr16 f 53.4225 2.7277 58.7842 48.0608
B6.PWD-Chr16 m 56.2737 2.7277 61.6354 50.9121
B6.PWD-Chr17 f 51.3675 2.7277 56.7292 46.0058
B6.PWD-Chr17 m 34.18 2.7277 39.5417 28.8183
B6.PWD-Chr18 f 58.1388 2.7277 63.5004 52.7771
B6.PWD-Chr18 m 57.5288 2.7277 62.8904 52.1671
B6.PWD-Chr19 f 49.31 2.7277 54.6717 43.9483
B6.PWD-Chr19 m 46.4943 2.916 52.2262 40.7624
B6.PWD-Chr2 f 48.169 2.4397 52.9646 43.3734
B6.PWD-Chr2 m 38.5562 2.7277 43.9179 33.1946
B6.PWD-Chr3 f 30.9475 2.7277 36.3092 25.5858
B6.PWD-Chr3 m 24.1163 2.7277 29.4779 18.7546
B6.PWD-Chr5 f 49.5675 2.7277 54.9292 44.2058
B6.PWD-Chr5 m 49.0277 2.7277 54.3894 43.6661
B6.PWD-Chr6 f 21.6863 2.7277 27.0479 16.3246
B6.PWD-Chr6 m 28.8741 2.7277 34.2358 23.5125
B6.PWD-Chr8 f 44.466 3.4503 51.248 37.684
B6.PWD-Chr8 m 42.372 3.4503 49.154 35.59
B6.PWD-Chr9 f 46.0587 2.7277 51.4204 40.6971
B6.PWD-Chr9 m 47.2975 2.7277 52.6592 41.9358
B6.PWD-ChrX.1 f 46.6538 2.7277 52.0154 41.2921
B6.PWD-ChrX.1 m 52.7014 2.916 58.4333 46.9696
B6.PWD-ChrX.2 f 51.855 2.7277 57.2167 46.4933
B6.PWD-ChrX.2 m 35.6456 2.5717 40.7006 30.5905
B6.PWD-ChrX.3 f 32.625 2.7277 37.9867 27.2633
B6.PWD-ChrX.3 m 31.0538 2.7277 36.4154 25.6921
B6.PWD-ChrY f 45.2675 2.7277 50.6292 39.9058
B6.PWD-ChrY m 45.3337 2.7277 50.6954 39.9721
B6.PWD-mt f 46.9571 2.916 52.689 41.2253
B6.PWD-mt m 43.5725 2.7277 48.9342 38.2108
C57BL/6J f 57.5575 1.9288 61.3488 53.7662
C57BL/6J m 60.1919 1.9288 63.9832 56.4006
PWD/PhJ f 21.3657 2.916 27.0976 15.6338
PWD/PhJ m 20.4575 2.7277 25.8192 15.0958


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 39.0031 1.9288 42.7944 35.2118
B6.PWD-Chr10.1 both 43.1142 1.7924 46.6375 39.5909
B6.PWD-Chr10.2 both 49.0288 1.9288 52.82 45.2375
B6.PWD-Chr10.3 both 46.8124 1.9288 50.6037 43.0211
B6.PWD-Chr11.1 both 52.4896 1.5748 55.5851 49.394
B6.PWD-Chr11.2 both 42.9031 1.7724 46.3871 39.4192
B6.PWD-Chr11.3 both 41.5259 1.8298 45.1226 37.9292
B6.PWD-Chr12 both 49.2494 1.9288 53.0407 45.4581
B6.PWD-Chr13 both 58.2114 1.8744 61.8958 54.5269
B6.PWD-Chr14 both 59.6336 1.8298 63.2303 56.0369
B6.PWD-Chr15 both 44.8905 1.9965 48.8149 40.9662
B6.PWD-Chr16 both 54.8481 1.9288 58.6394 51.0568
B6.PWD-Chr17 both 42.7738 1.9288 46.565 38.9825
B6.PWD-Chr18 both 57.8338 1.9288 61.625 54.0425
B6.PWD-Chr19 both 47.9021 1.9965 51.8265 43.9778
B6.PWD-Chr2 both 43.3626 1.8298 46.9593 39.7659
B6.PWD-Chr3 both 27.5319 1.9288 31.3232 23.7406
B6.PWD-Chr5 both 49.2976 1.9288 53.0889 45.5063
B6.PWD-Chr6 both 25.2802 1.9288 29.0715 21.4889
B6.PWD-Chr8 both 43.419 2.4397 48.2146 38.6234
B6.PWD-Chr9 both 46.6781 1.9288 50.4694 42.8868
B6.PWD-ChrX.1 both 49.6776 1.9965 53.6019 45.7532
B6.PWD-ChrX.2 both 43.7503 1.8744 47.4347 40.0658
B6.PWD-ChrX.3 both 31.8394 1.9288 35.6307 28.0481
B6.PWD-ChrY both 45.3006 1.9288 49.0919 41.5093
B6.PWD-mt both 45.2648 1.9965 49.1892 41.3405
C57BL/6J both 58.8747 1.3638 61.5555 56.1939
PWD/PhJ both 20.9116 1.9965 24.8359 16.9873




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA