Phenotype measure:   Donahue6   pct_MONO_resident

ID, description, units MPD:41505   pct_MONO_resident   resident monocytes (percentage of viable WBC)   [%]
Data set, strains Donahue6   B6.PWD consomic w/par   28 strains     sex: both     age: 7wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue6 - resident monocytes (percentage of viable WBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means0.645   % 0.758   %
Median of the strain means0.444   % 0.545   %
SD of the strain means± 0.544 ± 0.656
Coefficient of variation (CV)0.843 0.865
Min–max range of strain means0.165   –   2.39   % 0.154   –   3.37   %
Mean sample size per strain8.3   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.2821 1.2821 8.4514 0.0038
strain 27 149.3886 5.5329 36.4707 < 0.0001
sex:strain 27 11.6272 0.4306 2.8386 < 0.0001
Residuals 419 63.5658 0.1517


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 2.39 0.974   8 0.344 0.408 0.72, 4.19 3.21
B6.PWD-Chr1 m 3.37 0.739   8 0.261 0.22 2.58, 4.84 3.98
B6.PWD-Chr10.1 f 0.601 0.546   11 0.165 0.909 0.087, 1.64 -0.08
B6.PWD-Chr10.1 m 0.378 0.336   8 0.119 0.891 0.1, 1.14 -0.58
B6.PWD-Chr10.2 f 0.366 0.192   8 0.068 0.525 0.24, 0.82 -0.51
B6.PWD-Chr10.2 m 0.39 0.105   8 0.0372 0.27 0.26, 0.58 -0.56
B6.PWD-Chr10.3 f 0.199 0.141   8 0.0499 0.71 0.068, 0.52 -0.82
B6.PWD-Chr10.3 m 0.239 0.0918   8 0.0325 0.384 0.093, 0.38 -0.79
B6.PWD-Chr11.1 f 0.303 0.114   12 0.0329 0.376 0.11, 0.42 -0.63
B6.PWD-Chr11.1 m 0.334 0.202   12 0.0582 0.604 0.084, 0.79 -0.65
B6.PWD-Chr11.2 f 0.251 0.192   9 0.0638 0.764 0.019, 0.53 -0.72
B6.PWD-Chr11.2 m 0.403 0.304   10 0.0962 0.755 0.14, 1.02 -0.54
B6.PWD-Chr11.3 f 0.209 0.172   8 0.0609 0.825 0.079, 0.6 -0.8
B6.PWD-Chr11.3 m 0.154 0.0826   10 0.0261 0.535 0.048, 0.34 -0.92
B6.PWD-Chr12 f 0.428 0.378   8 0.134 0.883 0.066, 0.89 -0.4
B6.PWD-Chr12 m 0.561 0.348   8 0.123 0.62 0.22, 1.18 -0.3
B6.PWD-Chr13 f 0.444 0.193   8 0.0683 0.435 0.17, 0.76 -0.37
B6.PWD-Chr13 m 0.699 0.363   9 0.121 0.52 0.35, 1.6 -0.09
B6.PWD-Chr14 f 0.283 0.0953   8 0.0337 0.337 0.1, 0.39 -0.67
B6.PWD-Chr14 m 0.488 0.195   10 0.0618 0.4 0.3, 0.89 -0.41
B6.PWD-Chr15 f 0.543 0.35   7 0.132 0.646 0.05, 1.01 -0.19
B6.PWD-Chr15 m 0.615 0.432   8 0.153 0.704 0.076, 1.1 -0.22
B6.PWD-Chr16 f 0.773 0.67   8 0.237 0.868 0.16, 2.1 0.24
B6.PWD-Chr16 m 0.626 0.56   8 0.198 0.894 0.16, 1.77 -0.2
B6.PWD-Chr17 f 0.444 0.252   8 0.089 0.568 -0.37
B6.PWD-Chr17 m 0.744 0.357   8 0.126 0.481 0.41, 1.45 -0.02
B6.PWD-Chr18 f 0.35 0.111   8 0.0393 0.318 0.17, 0.48 -0.54
B6.PWD-Chr18 m 0.316 0.0684   8 0.0242 0.216 0.23, 0.45 -0.67
B6.PWD-Chr19 f 0.59 0.808   8 0.286 1.37 0.046, 2.36 -0.1
B6.PWD-Chr19 m 1.02 0.61   7 0.231 0.597 0.27, 1.66 0.4
B6.PWD-Chr2 f 0.402 0.155   10 0.049 0.385 0.14, 0.66 -0.45
B6.PWD-Chr2 m 0.439 0.246   8 0.087 0.561 0.13, 0.77 -0.49
B6.PWD-Chr3 f 0.953 0.592   8 0.209 0.621 0.48, 2.18 0.57
B6.PWD-Chr3 m 1.83 0.404   8 0.143 0.221 1.44, 2.37 1.63
B6.PWD-Chr5 f 0.165 0.0702   8 0.0248 0.424 0.084, 0.3 -0.88
B6.PWD-Chr5 m 0.32 0.166   8 0.0588 0.521 0.066, 0.61 -0.67
B6.PWD-Chr6 f 1.83 0.652   8 0.231 0.357 0.44, 2.42 2.18
B6.PWD-Chr6 m 1.53 0.757   8 0.268 0.494 0.54, 2.76 1.18
B6.PWD-Chr8 f 0.968 0.535   5 0.239 0.553 0.49, 1.6 0.59
B6.PWD-Chr8 m 1.01 0.537   5 0.24 0.532 0.59, 1.87 0.38
B6.PWD-Chr9 f 0.351 0.214   8 0.0756 0.608 0.021, 0.66 -0.54
B6.PWD-Chr9 m 0.703 0.347   8 0.123 0.494 0.29, 1.19 -0.08
B6.PWD-ChrX.1 f 0.442 0.508   8 0.179 1.15 0.018, 1.12 -0.37
B6.PWD-ChrX.1 m 0.371 0.339   7 0.128 0.912 0.1, 0.93 -0.59
B6.PWD-ChrX.2 f 0.473 0.448   8 0.158 0.947 0.2, 1.54 -0.32
B6.PWD-ChrX.2 m 0.483 0.212   9 0.0706 0.438 0.12, 0.86 -0.42
B6.PWD-ChrX.3 f 1.86 0.768   8 0.272 0.412 0.81, 3.15 2.24
B6.PWD-ChrX.3 m 1.11 0.481   8 0.17 0.432 0.63, 2.1 0.54
B6.PWD-ChrY f 0.736 0.21   8 0.0742 0.285 0.47, 1.13 0.17
B6.PWD-ChrY m 0.91 0.172   8 0.0607 0.189 0.63, 1.25 0.23
B6.PWD-mt f 0.96 0.408   7 0.154 0.426 0.39, 1.42 0.58
B6.PWD-mt m 1.39 0.277   8 0.0978 0.199 0.95, 1.78 0.96
C57BL/6J f 0.246 0.108   16 0.027 0.439 0.054, 0.42 -0.73
C57BL/6J m 0.27 0.103   16 0.0257 0.381 0.095, 0.43 -0.74
PWD/PhJ f 0.489 0.125   7 0.0472 0.256 0.25, 0.64 -0.29
PWD/PhJ m 0.529 0.159   8 0.0562 0.301 0.26, 0.77 -0.35


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 2.385 0.1377 2.6557 2.1143
B6.PWD-Chr1 m 3.365 0.1377 3.6357 3.0943
B6.PWD-Chr10.1 f 0.6008 0.1174 0.8317 0.37
B6.PWD-Chr10.1 m 0.3775 0.1377 0.6482 0.1068
B6.PWD-Chr10.2 f 0.3662 0.1377 0.6369 0.0956
B6.PWD-Chr10.2 m 0.39 0.1377 0.6607 0.1193
B6.PWD-Chr10.3 f 0.1985 0.1377 0.4692 0.0
B6.PWD-Chr10.3 m 0.2391 0.1377 0.5098 0.0
B6.PWD-Chr11.1 f 0.3033 0.1124 0.5243 0.0823
B6.PWD-Chr11.1 m 0.3337 0.1124 0.5547 0.1127
B6.PWD-Chr11.2 f 0.2507 0.1298 0.5059 0.0
B6.PWD-Chr11.2 m 0.403 0.1232 0.6451 0.1609
B6.PWD-Chr11.3 f 0.2086 0.1377 0.4793 0.0
B6.PWD-Chr11.3 m 0.1543 0.1232 0.3964 0.0
B6.PWD-Chr12 f 0.4282 0.1377 0.6989 0.1576
B6.PWD-Chr12 m 0.5612 0.1377 0.8319 0.2906
B6.PWD-Chr13 f 0.4437 0.1377 0.7144 0.1731
B6.PWD-Chr13 m 0.6989 0.1298 0.9541 0.4437
B6.PWD-Chr14 f 0.2825 0.1377 0.5532 0.0118
B6.PWD-Chr14 m 0.488 0.1232 0.7301 0.2459
B6.PWD-Chr15 f 0.5429 0.1472 0.8322 0.2535
B6.PWD-Chr15 m 0.6145 0.1377 0.8852 0.3438
B6.PWD-Chr16 f 0.7725 0.1377 1.0432 0.5018
B6.PWD-Chr16 m 0.6262 0.1377 0.8969 0.3556
B6.PWD-Chr17 f 0.4437 0.1377 0.7144 0.1731
B6.PWD-Chr17 m 0.7437 0.1377 1.0144 0.4731
B6.PWD-Chr18 f 0.35 0.1377 0.6207 0.0793
B6.PWD-Chr18 m 0.3162 0.1377 0.5869 0.0456
B6.PWD-Chr19 f 0.5895 0.1377 0.8602 0.3188
B6.PWD-Chr19 m 1.0214 0.1472 1.3108 0.7321
B6.PWD-Chr2 f 0.402 0.1232 0.6441 0.1599
B6.PWD-Chr2 m 0.4388 0.1377 0.7094 0.1681
B6.PWD-Chr3 f 0.9525 0.1377 1.2232 0.6818
B6.PWD-Chr3 m 1.8262 0.1377 2.0969 1.5556
B6.PWD-Chr5 f 0.1655 0.1377 0.4362 0.0
B6.PWD-Chr5 m 0.3195 0.1377 0.5902 0.0488
B6.PWD-Chr6 f 1.8287 0.1377 2.0994 1.5581
B6.PWD-Chr6 m 1.5337 0.1377 1.8044 1.2631
B6.PWD-Chr8 f 0.968 0.1742 1.3104 0.6256
B6.PWD-Chr8 m 1.01 0.1742 1.3524 0.6676
B6.PWD-Chr9 f 0.3514 0.1377 0.6221 0.0807
B6.PWD-Chr9 m 0.7025 0.1377 0.9732 0.4318
B6.PWD-ChrX.1 f 0.4415 0.1377 0.7122 0.1708
B6.PWD-ChrX.1 m 0.3714 0.1472 0.6608 0.0821
B6.PWD-ChrX.2 f 0.4725 0.1377 0.7432 0.2018
B6.PWD-ChrX.2 m 0.4833 0.1298 0.7385 0.2281
B6.PWD-ChrX.3 f 1.8637 0.1377 2.1344 1.5931
B6.PWD-ChrX.3 m 1.1137 0.1377 1.3844 0.8431
B6.PWD-ChrY f 0.7362 0.1377 1.0069 0.4656
B6.PWD-ChrY m 0.91 0.1377 1.1807 0.6393
B6.PWD-mt f 0.96 0.1472 1.2494 0.6706
B6.PWD-mt m 1.3875 0.1377 1.6582 1.1168
C57BL/6J f 0.2458 0.0974 0.4372 0.0543
C57BL/6J m 0.2697 0.0974 0.4611 0.0783
PWD/PhJ f 0.4886 0.1472 0.7779 0.1992
PWD/PhJ m 0.5288 0.1377 0.7994 0.2581


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 2.875 0.0974 3.0664 2.6836
B6.PWD-Chr10.1 both 0.4892 0.0905 0.667 0.3113
B6.PWD-Chr10.2 both 0.3781 0.0974 0.5695 0.1867
B6.PWD-Chr10.3 both 0.2188 0.0974 0.4102 0.0274
B6.PWD-Chr11.1 both 0.3185 0.0795 0.4748 0.1622
B6.PWD-Chr11.2 both 0.3268 0.0895 0.5027 0.1509
B6.PWD-Chr11.3 both 0.1815 0.0924 0.363 0.0
B6.PWD-Chr12 both 0.4947 0.0974 0.6862 0.3033
B6.PWD-Chr13 both 0.5713 0.0946 0.7573 0.3853
B6.PWD-Chr14 both 0.3852 0.0924 0.5668 0.2037
B6.PWD-Chr15 both 0.5787 0.1008 0.7768 0.3806
B6.PWD-Chr16 both 0.6994 0.0974 0.8908 0.508
B6.PWD-Chr17 both 0.5937 0.0974 0.7852 0.4023
B6.PWD-Chr18 both 0.3331 0.0974 0.5245 0.1417
B6.PWD-Chr19 both 0.8055 0.1008 1.0036 0.6073
B6.PWD-Chr2 both 0.4204 0.0924 0.602 0.2388
B6.PWD-Chr3 both 1.3894 0.0974 1.5808 1.198
B6.PWD-Chr5 both 0.2425 0.0974 0.4339 0.0511
B6.PWD-Chr6 both 1.6812 0.0974 1.8727 1.4898
B6.PWD-Chr8 both 0.989 0.1232 1.2311 0.7469
B6.PWD-Chr9 both 0.5269 0.0974 0.7183 0.3355
B6.PWD-ChrX.1 both 0.4065 0.1008 0.6046 0.2083
B6.PWD-ChrX.2 both 0.4779 0.0946 0.6639 0.2919
B6.PWD-ChrX.3 both 1.4887 0.0974 1.6802 1.2973
B6.PWD-ChrY both 0.8231 0.0974 1.0145 0.6317
B6.PWD-mt both 1.1737 0.1008 1.3719 0.9756
C57BL/6J both 0.2577 0.0689 0.3931 0.1224
PWD/PhJ both 0.5087 0.1008 0.7068 0.3105




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA