Project measure / variable:   Donahue6   pct_MONO_inflam

ID, description, units MPD:41504   pct_MONO_inflam   inflammatory monocytes (percentage of viable WBC)   [%]  
Data set, strains Donahue6   B6.PWD consomic w/par   28 strains     sex: both     age: 7wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Donahue6 - inflammatory monocytes (percentage of viable WBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means4.71   % 6.33   %
Median of the strain means4.29   % 5.51   %
SD of the strain means± 2.48 ± 3.15
Coefficient of variation (CV)0.526 0.497
Min–max range of strain means0.970   –   12.2   % 1.16   –   15.0   %
Mean sample size per strain8.3   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 271.2118 271.2118 52.7897 < 0.0001
strain 27 3144.7569 116.4725 22.6706 < 0.0001
sex:strain 27 529.8304 19.6233 3.8196 < 0.0001
Residuals 419 2152.6503 5.1376


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 4.95 1.61   8 0.571 0.326 2.7, 7.3 0.1
B6.PWD-Chr1 m 6.74 2.01   8 0.71 0.298 4.8, 9.98 0.13
B6.PWD-Chr10.1 f 5.19 3.64   11 1.1 0.701 1.0, 12.3 0.2
B6.PWD-Chr10.1 m 4.44 2.17   8 0.766 0.488 1.38, 7.57 -0.6
B6.PWD-Chr10.2 f 4.54 1.38   8 0.487 0.303 2.53, 7.35 -0.07
B6.PWD-Chr10.2 m 5.78 0.816   8 0.289 0.141 4.8, 7.01 -0.18
B6.PWD-Chr10.3 f 2.93 1.68   8 0.595 0.574 0.86, 5.36 -0.72
B6.PWD-Chr10.3 m 3.92 1.21   8 0.428 0.309 1.15, 5.1 -0.77
B6.PWD-Chr11.1 f 4.53 1.21   12 0.35 0.267 2.22, 6.16 -0.07
B6.PWD-Chr11.1 m 5.65 1.83   12 0.529 0.324 2.54, 8.7 -0.22
B6.PWD-Chr11.2 f 2.51 1.35   9 0.45 0.538 0.45, 4.16 -0.89
B6.PWD-Chr11.2 m 5.87 4.02   10 1.27 0.685 1.55, 14.2 -0.15
B6.PWD-Chr11.3 f 1.53 1.29   8 0.456 0.842 0.56, 4.16 -1.28
B6.PWD-Chr11.3 m 1.16 0.25   10 0.0789 0.216 0.76, 1.6 -1.64
B6.PWD-Chr12 f 3.62 2.01   8 0.709 0.553 1.55, 6.49 -0.44
B6.PWD-Chr12 m 4.88 2.17   8 0.767 0.445 2.66, 8.05 -0.46
B6.PWD-Chr13 f 3.6 1.4   8 0.496 0.39 1.93, 5.7 -0.45
B6.PWD-Chr13 m 5.03 1.91   9 0.638 0.381 3.11, 9.33 -0.41
B6.PWD-Chr14 f 3.02 1.1   8 0.389 0.364 0.48, 4.09 -0.68
B6.PWD-Chr14 m 3.79 0.7   10 0.221 0.185 2.75, 5.28 -0.81
B6.PWD-Chr15 f 6.14 3.25   7 1.23 0.53 1.0, 9.86 0.58
B6.PWD-Chr15 m 4.9 2.42   8 0.856 0.494 1.67, 8.14 -0.45
B6.PWD-Chr16 f 5.3 2.34   8 0.829 0.442 2.44, 8.78 0.24
B6.PWD-Chr16 m 5.37 2.69   8 0.95 0.5 2.18, 10.4 -0.31
B6.PWD-Chr17 f 3.5 0.593   8 0.21 0.169 2.51, 4.59 -0.49
B6.PWD-Chr17 m 10.6 4.42   8 1.56 0.416 6.82, 17.6 1.36
B6.PWD-Chr18 f 4.18 1.08   8 0.382 0.258 2.37, 5.53 -0.21
B6.PWD-Chr18 m 4.54 1.35   8 0.479 0.298 2.5, 5.74 -0.57
B6.PWD-Chr19 f 3.96 1.09   8 0.386 0.275 1.93, 5.82 -0.3
B6.PWD-Chr19 m 4.81 0.444   7 0.168 0.0924 4.17, 5.35 -0.48
B6.PWD-Chr2 f 5.01 1.2   10 0.378 0.238 3.31, 6.66 0.12
B6.PWD-Chr2 m 7.65 2.43   8 0.859 0.317 3.69, 11.6 0.42
B6.PWD-Chr3 f 7.76 3.68   8 1.3 0.474 4.58, 15.5 1.23
B6.PWD-Chr3 m 15.0 3.56   8 1.26 0.237 10.6, 22.3 2.76
B6.PWD-Chr5 f 4.07 1.32   8 0.468 0.325 2.4, 6.11 -0.26
B6.PWD-Chr5 m 4.83 1.9   8 0.671 0.393 0.97, 7.15 -0.48
B6.PWD-Chr6 f 12.2 3.21   8 1.13 0.263 5.71, 15.1 3.02
B6.PWD-Chr6 m 12.4 5.32   8 1.88 0.428 1.79, 19.9 1.93
B6.PWD-Chr8 f 3.88 0.795   5 0.356 0.205 3.01, 4.92 -0.33
B6.PWD-Chr8 m 6.35 2.88   5 1.29 0.454 4.05, 11.1 0.01
B6.PWD-Chr9 f 4.14 1.87   8 0.662 0.452 0.58, 5.85 -0.23
B6.PWD-Chr9 m 8.18 3.58   8 1.27 0.438 3.77, 15.4 0.59
B6.PWD-ChrX.1 f 4.39 3.41   8 1.21 0.778 0.7, 9.65 -0.13
B6.PWD-ChrX.1 m 4.78 3.35   7 1.27 0.7 2.22, 11.2 -0.49
B6.PWD-ChrX.2 f 4.56 0.81   8 0.286 0.178 3.64, 6.33 -0.06
B6.PWD-ChrX.2 m 10.2 2.54   9 0.846 0.249 7.83, 16.5 1.23
B6.PWD-ChrX.3 f 11.7 3.78   8 1.34 0.324 6.43, 15.7 2.82
B6.PWD-ChrX.3 m 10.4 2.13   8 0.755 0.205 6.88, 13.8 1.29
B6.PWD-ChrY f 6.14 2.32   8 0.822 0.379 3.78, 11.5 0.58
B6.PWD-ChrY m 8.45 2.03   8 0.718 0.24 5.8, 10.7 0.67
B6.PWD-mt f 5.03 1.06   7 0.4 0.21 4.03, 6.44 0.13
B6.PWD-mt m 7.14 1.73   8 0.611 0.242 5.47, 9.9 0.26
C57BL/6J f 2.42 1.21   16 0.302 0.499 0.77, 4.64 -0.92
C57BL/6J m 2.71 1.55   16 0.388 0.573 0.45, 5.08 -1.15
PWD/PhJ f 0.97 0.137   7 0.0518 0.141 0.84, 1.16 -1.51
PWD/PhJ m 1.7 0.616   8 0.218 0.361 1.11, 3.0 -1.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 4.955 0.8014 6.5302 3.3798
B6.PWD-Chr1 m 6.7388 0.8014 8.314 5.1635
B6.PWD-Chr10.1 f 5.1891 0.6834 6.5324 3.8457
B6.PWD-Chr10.1 m 4.4438 0.8014 6.019 2.8685
B6.PWD-Chr10.2 f 4.5413 0.8014 6.1165 2.966
B6.PWD-Chr10.2 m 5.775 0.8014 7.3502 4.1998
B6.PWD-Chr10.3 f 2.9312 0.8014 4.5065 1.356
B6.PWD-Chr10.3 m 3.9175 0.8014 5.4927 2.3423
B6.PWD-Chr11.1 f 4.5342 0.6543 5.8203 3.248
B6.PWD-Chr11.1 m 5.6542 0.6543 6.9403 4.368
B6.PWD-Chr11.2 f 2.5056 0.7555 3.9907 1.0204
B6.PWD-Chr11.2 m 5.87 0.7168 7.2789 4.4611
B6.PWD-Chr11.3 f 1.5313 0.8014 3.1065 0.0
B6.PWD-Chr11.3 m 1.157 0.7168 2.5659 0.0
B6.PWD-Chr12 f 3.6237 0.8014 5.199 2.0485
B6.PWD-Chr12 m 4.8787 0.8014 6.454 3.3035
B6.PWD-Chr13 f 3.5975 0.8014 5.1727 2.0223
B6.PWD-Chr13 m 5.0278 0.7555 6.5129 3.5427
B6.PWD-Chr14 f 3.0225 0.8014 4.5977 1.4473
B6.PWD-Chr14 m 3.79 0.7168 5.1989 2.3811
B6.PWD-Chr15 f 6.1357 0.8567 7.8197 4.4517
B6.PWD-Chr15 m 4.8975 0.8014 6.4727 3.3223
B6.PWD-Chr16 f 5.2987 0.8014 6.874 3.7235
B6.PWD-Chr16 m 5.37 0.8014 6.9452 3.7948
B6.PWD-Chr17 f 3.5038 0.8014 5.079 1.9285
B6.PWD-Chr17 m 10.6313 0.8014 12.2065 9.056
B6.PWD-Chr18 f 4.185 0.8014 5.7602 2.6098
B6.PWD-Chr18 m 4.54 0.8014 6.1152 2.9648
B6.PWD-Chr19 f 3.9638 0.8014 5.539 2.3885
B6.PWD-Chr19 m 4.8114 0.8567 6.4954 3.1275
B6.PWD-Chr2 f 5.014 0.7168 6.4229 3.6051
B6.PWD-Chr2 m 7.6537 0.8014 9.229 6.0785
B6.PWD-Chr3 f 7.7625 0.8014 9.3377 6.1873
B6.PWD-Chr3 m 15.0 0.8014 16.5752 13.4248
B6.PWD-Chr5 f 4.0712 0.8014 5.6465 2.496
B6.PWD-Chr5 m 4.8287 0.8014 6.404 3.2535
B6.PWD-Chr6 f 12.2137 0.8014 13.789 10.6385
B6.PWD-Chr6 m 12.4112 0.8014 13.9865 10.836
B6.PWD-Chr8 f 3.884 1.0137 5.8765 1.8915
B6.PWD-Chr8 m 6.348 1.0137 8.3405 4.3555
B6.PWD-Chr9 f 4.1387 0.8014 5.714 2.5635
B6.PWD-Chr9 m 8.1812 0.8014 9.7565 6.606
B6.PWD-ChrX.1 f 4.385 0.8014 5.9602 2.8098
B6.PWD-ChrX.1 m 4.7843 0.8567 6.4683 3.1003
B6.PWD-ChrX.2 f 4.5625 0.8014 6.1377 2.9873
B6.PWD-ChrX.2 m 10.2044 0.7555 11.6896 8.7193
B6.PWD-ChrX.3 f 11.6787 0.8014 13.254 10.1035
B6.PWD-ChrX.3 m 10.42 0.8014 11.9952 8.8448
B6.PWD-ChrY f 6.135 0.8014 7.7102 4.5598
B6.PWD-ChrY m 8.4462 0.8014 10.0215 6.871
B6.PWD-mt f 5.0271 0.8567 6.7111 3.3432
B6.PWD-mt m 7.14 0.8014 8.7152 5.5648
C57BL/6J f 2.4206 0.5667 3.5345 1.3068
C57BL/6J m 2.71 0.5667 3.8238 1.5962
PWD/PhJ f 0.97 0.8567 2.654 0.0
PWD/PhJ m 1.7038 0.8014 3.279 0.1285


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 5.8469 0.5667 6.9607 4.733
B6.PWD-Chr10.1 both 4.8164 0.5266 5.8515 3.7813
B6.PWD-Chr10.2 both 5.1581 0.5667 6.272 4.0443
B6.PWD-Chr10.3 both 3.4244 0.5667 4.5382 2.3105
B6.PWD-Chr11.1 both 5.0942 0.4627 6.0036 4.1847
B6.PWD-Chr11.2 both 4.1878 0.5207 5.2113 3.1642
B6.PWD-Chr11.3 both 1.3441 0.5376 2.4008 0.2874
B6.PWD-Chr12 both 4.2512 0.5667 5.3651 3.1374
B6.PWD-Chr13 both 4.3126 0.5507 5.3951 3.2302
B6.PWD-Chr14 both 3.4062 0.5376 4.4629 2.3496
B6.PWD-Chr15 both 5.5166 0.5865 6.6695 4.3637
B6.PWD-Chr16 both 5.3344 0.5667 6.4482 4.2205
B6.PWD-Chr17 both 7.0675 0.5667 8.1813 5.9537
B6.PWD-Chr18 both 4.3625 0.5667 5.4763 3.2487
B6.PWD-Chr19 both 4.3876 0.5865 5.5405 3.2347
B6.PWD-Chr2 both 6.3339 0.5376 7.3906 5.2772
B6.PWD-Chr3 both 11.3813 0.5667 12.4951 10.2674
B6.PWD-Chr5 both 4.45 0.5667 5.5638 3.3362
B6.PWD-Chr6 both 12.3125 0.5667 13.4263 11.1987
B6.PWD-Chr8 both 5.116 0.7168 6.5249 3.7071
B6.PWD-Chr9 both 6.16 0.5667 7.2738 5.0462
B6.PWD-ChrX.1 both 4.5846 0.5865 5.7376 3.4317
B6.PWD-ChrX.2 both 7.3835 0.5507 8.4659 6.301
B6.PWD-ChrX.3 both 11.0494 0.5667 12.1632 9.9355
B6.PWD-ChrY both 7.2906 0.5667 8.4045 6.1768
B6.PWD-mt both 6.0836 0.5865 7.2365 4.9306
C57BL/6J both 2.5653 0.4007 3.3529 1.7777
PWD/PhJ both 1.3369 0.5865 2.4898 0.1839




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA