Project measure / variable:   Donahue5   pct_CD4

ID, description, units MPD:41410   pct_CD4   CD4 T cells (percentage of viable WBC)   [%]  
Data set, strains Donahue5   B6.A consomic w/par   22 strains     sex: both     age: 7wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue5 - CD4 T cells (percentage of viable WBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains22 strains
Mean of the strain means10.7   % 9.46   %
Median of the strain means10.4   % 8.51   %
SD of the strain means± 2.79 ± 2.72
Coefficient of variation (CV)0.261 0.287
Min–max range of strain means7.03   –   16.2   % 4.66   –   15.4   %
Mean sample size per strain8.4   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 177.7705 177.7705 14.4621 0.0002
strain 21 2452.0405 116.7638 9.499 < 0.0001
sex:strain 21 257.3079 12.2528 0.9968 0.4666
Residuals 341 4191.6366 12.2922


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 11.4 5.46   16 1.37 0.48 4.38, 22.1 0.25
A/J m 6.06 3.03   16 0.757 0.499 2.69, 11.6 -1.25
B6.A-Chr1 f 13.7 1.36   8 0.481 0.0992 11.7, 15.9 1.08
B6.A-Chr1 m 12.2 1.77   8 0.627 0.146 8.98, 14.7 1.01
B6.A-Chr10 f 9.16 6.67   8 2.36 0.728 2.8, 16.9 -0.55
B6.A-Chr10 m 7.5 4.79   8 1.69 0.638 2.44, 14.9 -0.72
B6.A-Chr11 f 12.1 6.67   8 2.36 0.551 4.95, 19.4 0.5
B6.A-Chr11 m 12.5 4.68   8 1.66 0.373 6.0, 18.7 1.12
B6.A-Chr12 f 11.4 1.85   8 0.655 0.163 9.57, 14.6 0.25
B6.A-Chr12 m 10.5 1.38   8 0.489 0.132 8.41, 12.6 0.38
B6.A-Chr13 f 8.96 2.27   8 0.803 0.253 5.21, 11.5 -0.62
B6.A-Chr13 m 8.9 3.55   8 1.26 0.399 5.41, 14.8 -0.21
B6.A-Chr14 f 11.0 5.46   8 1.93 0.495 4.72, 17.3 0.11
B6.A-Chr14 m 12.0 4.08   8 1.44 0.341 6.72, 16.2 0.93
B6.A-Chr15 f 9.79 3.56   8 1.26 0.363 1.42, 12.4 -0.32
B6.A-Chr15 m 7.82 0.844   8 0.298 0.108 6.58, 8.85 -0.6
B6.A-Chr16 f 8.72 3.07   8 1.09 0.352 4.86, 13.1 -0.71
B6.A-Chr16 m 8.01 4.79   8 1.69 0.598 1.52, 13.2 -0.53
B6.A-Chr17 f 15.9 1.16   8 0.41 0.0727 14.7, 18.0 1.87
B6.A-Chr17 m 14.4 1.11   8 0.392 0.077 12.6, 15.6 1.82
B6.A-Chr18 f 13.6 5.35   8 1.89 0.395 7.11, 21.7 1.04
B6.A-Chr18 m 11.0 1.94   8 0.686 0.176 8.32, 14.5 0.56
B6.A-Chr19 f 8.16 3.11   8 1.1 0.382 4.12, 13.4 -0.91
B6.A-Chr19 m 8.12 1.91   8 0.675 0.235 5.09, 10.6 -0.49
B6.A-Chr2 f 12.3 1.78   9 0.594 0.145 9.64, 16.2 0.58
B6.A-Chr2 m 9.47 3.63   8 1.28 0.383 1.72, 13.7 0.0
B6.A-Chr3 f 14.6 7.36   8 2.6 0.506 6.92, 22.9 1.4
B6.A-Chr3 m 11.4 5.41   8 1.91 0.473 6.25, 21.4 0.71
B6.A-Chr4 f 8.98 1.13   8 0.4 0.126 7.21, 10.6 -0.62
B6.A-Chr4 m 6.92 1.09   8 0.385 0.157 5.2, 9.0 -0.94
B6.A-Chr5 f 7.03 1.24   8 0.437 0.176 5.31, 9.29 -1.31
B6.A-Chr5 m 7.57 0.968   8 0.342 0.128 6.09, 9.14 -0.7
B6.A-Chr6 f 16.2 1.48   8 0.524 0.0917 14.2, 18.5 1.97
B6.A-Chr6 m 15.4 1.36   8 0.479 0.0882 13.5, 17.9 2.18
B6.A-Chr7 f 8.49 4.61   8 1.63 0.543 4.04, 16.7 -0.79
B6.A-Chr7 m 7.62 3.02   8 1.07 0.395 3.13, 13.2 -0.68
B6.A-Chr8 f 11.1 4.67   8 1.65 0.419 6.6, 18.6 0.15
B6.A-Chr8 m 10.5 2.62   8 0.927 0.25 6.79, 14.6 0.38
B6.A-Chr9 f 7.47 0.984   8 0.348 0.132 5.91, 8.63 -1.16
B6.A-Chr9 m 7.76 1.47   8 0.519 0.189 5.92, 10.5 -0.63
B6.A-ChrX f 7.3 1.93   8 0.684 0.265 4.55, 10.5 -1.22
B6.A-ChrX m 4.66 1.67   8 0.59 0.358 1.97, 6.81 -1.77
C57BL/6J f 7.94 2.72   16 0.681 0.343 3.68, 12.7 -0.99
C57BL/6J m 7.91 3.0   16 0.749 0.379 2.1, 12.3 -0.57


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 11.3763 0.8765 13.1003 9.6522
A/J m 6.0644 0.8765 7.7884 4.3403
B6.A-Chr1 f 13.7 1.2396 16.1382 11.2618
B6.A-Chr1 m 12.1725 1.2396 14.6107 9.7343
B6.A-Chr10 f 9.1613 1.2396 11.5994 6.7231
B6.A-Chr10 m 7.5025 1.2396 9.9407 5.0643
B6.A-Chr11 f 12.0962 1.2396 14.5344 9.6581
B6.A-Chr11 m 12.55 1.2396 14.9882 10.1118
B6.A-Chr12 f 11.3962 1.2396 13.8344 8.9581
B6.A-Chr12 m 10.4725 1.2396 12.9107 8.0343
B6.A-Chr13 f 8.9587 1.2396 11.3969 6.5206
B6.A-Chr13 m 8.9013 1.2396 11.3394 6.4631
B6.A-Chr14 f 11.0263 1.2396 13.4644 8.5881
B6.A-Chr14 m 11.9662 1.2396 14.4044 9.5281
B6.A-Chr15 f 9.785 1.2396 12.2232 7.3468
B6.A-Chr15 m 7.8237 1.2396 10.2619 5.3856
B6.A-Chr16 f 8.7175 1.2396 11.1557 6.2793
B6.A-Chr16 m 8.0062 1.2396 10.4444 5.5681
B6.A-Chr17 f 15.9375 1.2396 18.3757 13.4993
B6.A-Chr17 m 14.3875 1.2396 16.8257 11.9493
B6.A-Chr18 f 13.5525 1.2396 15.9907 11.1143
B6.A-Chr18 m 10.9937 1.2396 13.4319 8.5556
B6.A-Chr19 f 8.1638 1.2396 10.6019 5.7256
B6.A-Chr19 m 8.1162 1.2396 10.5544 5.6781
B6.A-Chr2 f 12.3156 1.1687 14.6143 10.0168
B6.A-Chr2 m 9.4663 1.2396 11.9044 7.0281
B6.A-Chr3 f 14.55 1.2396 16.9882 12.1118
B6.A-Chr3 m 11.4387 1.2396 13.8769 9.0006
B6.A-Chr4 f 8.9763 1.2396 11.4144 6.5381
B6.A-Chr4 m 6.9175 1.2396 9.3557 4.4793
B6.A-Chr5 f 7.025 1.2396 9.4632 4.5868
B6.A-Chr5 m 7.5712 1.2396 10.0094 5.1331
B6.A-Chr6 f 16.1625 1.2396 18.6007 13.7243
B6.A-Chr6 m 15.375 1.2396 17.8132 12.9368
B6.A-Chr7 f 8.49 1.2396 10.9282 6.0518
B6.A-Chr7 m 7.625 1.2396 10.0632 5.1868
B6.A-Chr8 f 11.1387 1.2396 13.5769 8.7006
B6.A-Chr8 m 10.4975 1.2396 12.9357 8.0593
B6.A-Chr9 f 7.475 1.2396 9.9132 5.0368
B6.A-Chr9 m 7.7587 1.2396 10.1969 5.3206
B6.A-ChrX f 7.2988 1.2396 9.7369 4.8606
B6.A-ChrX m 4.6562 1.2396 7.0944 2.2181
C57BL/6J f 7.935 0.8765 9.659 6.211
C57BL/6J m 7.9088 0.8765 9.6328 6.1847


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 8.7203 0.6198 9.9394 7.5012
B6.A-Chr1 both 12.9363 0.8765 14.6603 11.2122
B6.A-Chr10 both 8.3319 0.8765 10.0559 6.6078
B6.A-Chr11 both 12.3231 0.8765 14.0472 10.5991
B6.A-Chr12 both 10.9344 0.8765 12.6584 9.2103
B6.A-Chr13 both 8.93 0.8765 10.654 7.206
B6.A-Chr14 both 11.4962 0.8765 13.2203 9.7722
B6.A-Chr15 both 8.8044 0.8765 10.5284 7.0803
B6.A-Chr16 both 8.3619 0.8765 10.0859 6.6378
B6.A-Chr17 both 15.1625 0.8765 16.8865 13.4385
B6.A-Chr18 both 12.2731 0.8765 13.9972 10.5491
B6.A-Chr19 both 8.14 0.8765 9.864 6.416
B6.A-Chr2 both 10.8909 0.8518 12.5664 9.2154
B6.A-Chr3 both 12.9944 0.8765 14.7184 11.2703
B6.A-Chr4 both 7.9469 0.8765 9.6709 6.2228
B6.A-Chr5 both 7.2981 0.8765 9.0222 5.5741
B6.A-Chr6 both 15.7687 0.8765 17.4928 14.0447
B6.A-Chr7 both 8.0575 0.8765 9.7815 6.3335
B6.A-Chr8 both 10.8181 0.8765 12.5422 9.0941
B6.A-Chr9 both 7.6169 0.8765 9.3409 5.8928
B6.A-ChrX both 5.9775 0.8765 7.7015 4.2535
C57BL/6J both 7.9219 0.6198 9.141 6.7028




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA