Project measure / variable:   Donahue5   pct_T_cells

ID, description, units MPD:41409   pct_T_cells   T cells (percentage of viable WBC)   [%]  
Data set, strains Donahue5   B6.A consomic w/par   22 strains     sex: both     age: 7wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Donahue5 - T cells (percentage of viable WBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains22 strains
Mean of the strain means23.7   % 21.3   %
Median of the strain means22.7   % 20.1   %
SD of the strain means± 6.41 ± 7.44
Coefficient of variation (CV)0.270 0.349
Min–max range of strain means15.5   –   37.1   % 10.9   –   41.6   %
Mean sample size per strain8.4   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 646.5727 646.5727 18.6747 < 0.0001
strain 21 16492.0241 785.3345 22.6825 < 0.0001
sex:strain 21 1142.7802 54.4181 1.5717 0.0537
Residuals 341 11806.4151 34.6229


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 18.7 6.53   16 1.63 0.349 9.56, 30.4 -0.78
A/J m 10.9 4.51   16 1.13 0.414 5.38, 19.1 -1.4
B6.A-Chr1 f 24.6 2.38   8 0.843 0.0969 21.1, 27.9 0.14
B6.A-Chr1 m 20.8 2.59   8 0.917 0.125 16.4, 25.0 -0.07
B6.A-Chr10 f 37.0 6.24   8 2.21 0.168 25.6, 47.8 2.07
B6.A-Chr10 m 32.1 12.2   8 4.31 0.379 20.3, 57.6 1.45
B6.A-Chr11 f 21.3 11.2   8 3.95 0.523 9.82, 33.3 -0.38
B6.A-Chr11 m 21.7 6.8   8 2.4 0.313 11.5, 30.0 0.05
B6.A-Chr12 f 23.5 2.51   8 0.888 0.107 20.9, 27.4 -0.03
B6.A-Chr12 m 19.6 2.95   8 1.04 0.15 15.7, 22.9 -0.23
B6.A-Chr13 f 25.5 4.47   8 1.58 0.175 18.8, 30.6 0.28
B6.A-Chr13 m 24.1 6.34   8 2.24 0.263 18.1, 35.4 0.37
B6.A-Chr14 f 21.5 11.1   8 3.91 0.513 9.64, 34.1 -0.35
B6.A-Chr14 m 22.3 8.07   8 2.85 0.362 11.9, 30.9 0.13
B6.A-Chr15 f 17.8 6.37   8 2.25 0.357 2.78, 23.6 -0.92
B6.A-Chr15 m 15.0 1.31   8 0.465 0.0874 13.5, 17.4 -0.85
B6.A-Chr16 f 18.6 2.78   8 0.984 0.15 13.9, 22.9 -0.8
B6.A-Chr16 m 16.8 5.93   8 2.1 0.354 8.43, 24.1 -0.61
B6.A-Chr17 f 37.1 2.55   8 0.902 0.0688 32.5, 41.3 2.09
B6.A-Chr17 m 33.0 3.56   8 1.26 0.108 29.0, 38.1 1.57
B6.A-Chr18 f 28.1 11.2   8 3.95 0.398 13.8, 43.0 0.68
B6.A-Chr18 m 23.2 4.2   8 1.49 0.181 16.6, 30.7 0.25
B6.A-Chr19 f 21.9 6.5   8 2.3 0.298 14.7, 32.3 -0.28
B6.A-Chr19 m 19.8 3.9   8 1.38 0.197 13.4, 24.8 -0.2
B6.A-Chr2 f 24.9 2.79   9 0.929 0.112 20.9, 30.5 0.18
B6.A-Chr2 m 19.2 5.78   8 2.04 0.301 6.11, 24.4 -0.28
B6.A-Chr3 f 26.5 12.9   8 4.55 0.485 13.2, 40.4 0.43
B6.A-Chr3 m 20.3 8.8   8 3.11 0.433 10.8, 37.2 -0.14
B6.A-Chr4 f 19.2 1.72   8 0.608 0.0897 16.5, 21.7 -0.71
B6.A-Chr4 m 13.3 1.67   8 0.589 0.125 10.1, 15.8 -1.08
B6.A-Chr5 f 15.5 1.36   8 0.482 0.0878 14.0, 18.2 -1.28
B6.A-Chr5 m 16.0 1.27   8 0.448 0.0794 13.3, 17.2 -0.71
B6.A-Chr6 f 29.9 1.84   8 0.649 0.0615 26.9, 32.4 0.96
B6.A-Chr6 m 26.7 1.99   8 0.704 0.0745 23.6, 30.4 0.72
B6.A-Chr7 f 34.2 6.71   8 2.37 0.196 24.4, 44.3 1.63
B6.A-Chr7 m 41.6 6.33   8 2.24 0.152 34.5, 53.9 2.72
B6.A-Chr8 f 25.1 3.85   8 1.36 0.153 20.2, 31.6 0.21
B6.A-Chr8 m 28.2 9.89   8 3.5 0.351 21.0, 51.7 0.92
B6.A-Chr9 f 15.8 2.14   8 0.756 0.136 12.3, 18.0 -1.24
B6.A-Chr9 m 15.8 2.53   8 0.894 0.16 13.1, 20.3 -0.74
B6.A-ChrX f 17.4 3.19   8 1.13 0.183 13.6, 22.6 -0.99
B6.A-ChrX m 12.1 3.14   8 1.11 0.259 7.17, 16.8 -1.24
C57BL/6J f 17.8 4.54   16 1.13 0.255 10.9, 25.9 -0.92
C57BL/6J m 16.5 4.28   16 1.07 0.259 7.48, 22.6 -0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 18.7138 1.471 21.6072 15.8203
A/J m 10.885 1.471 13.7784 7.9916
B6.A-Chr1 f 24.6175 2.0804 28.7094 20.5256
B6.A-Chr1 m 20.7594 2.0804 24.8513 16.6674
B6.A-Chr10 f 37.0363 2.0804 41.1282 32.9443
B6.A-Chr10 m 32.1413 2.0804 36.2332 28.0493
B6.A-Chr11 f 21.3413 2.0804 25.4332 17.2493
B6.A-Chr11 m 21.7475 2.0804 25.8394 17.6556
B6.A-Chr12 f 23.4925 2.0804 27.5844 19.4006
B6.A-Chr12 m 19.61 2.0804 23.7019 15.5181
B6.A-Chr13 f 25.5175 2.0804 29.6094 21.4256
B6.A-Chr13 m 24.12 2.0804 28.2119 20.0281
B6.A-Chr14 f 21.5463 2.0804 25.6382 17.4543
B6.A-Chr14 m 22.3223 2.0804 26.4142 18.2303
B6.A-Chr15 f 17.8479 2.0804 21.9398 13.7559
B6.A-Chr15 m 15.0388 2.0804 19.1307 10.9468
B6.A-Chr16 f 18.5725 2.0804 22.6644 14.4806
B6.A-Chr16 m 16.7725 2.0804 20.8644 12.6806
B6.A-Chr17 f 37.105 2.0804 41.1969 33.0131
B6.A-Chr17 m 32.9762 2.0804 37.0682 28.8843
B6.A-Chr18 f 28.08 2.0804 32.1719 23.9881
B6.A-Chr18 m 23.2437 2.0804 27.3357 19.1518
B6.A-Chr19 f 21.85 2.0804 25.9419 17.7581
B6.A-Chr19 m 19.805 2.0804 23.8969 15.7131
B6.A-Chr2 f 24.92 1.9614 28.7779 21.0621
B6.A-Chr2 m 19.1875 2.0804 23.2794 15.0956
B6.A-Chr3 f 26.5325 2.0804 30.6244 22.4406
B6.A-Chr3 m 20.3425 2.0804 24.4344 16.2506
B6.A-Chr4 f 19.1825 2.0804 23.2744 15.0906
B6.A-Chr4 m 13.3438 2.0804 17.4357 9.2518
B6.A-Chr5 f 15.5413 2.0804 19.6332 11.4493
B6.A-Chr5 m 15.96 2.0804 20.0519 11.8681
B6.A-Chr6 f 29.8788 2.0804 33.9707 25.7868
B6.A-Chr6 m 26.7237 2.0804 30.8157 22.6318
B6.A-Chr7 f 34.235 2.0804 38.3269 30.1431
B6.A-Chr7 m 41.5712 2.0804 45.6632 37.4793
B6.A-Chr8 f 25.0887 2.0804 29.1807 20.9968
B6.A-Chr8 m 28.1738 2.0804 32.2657 24.0818
B6.A-Chr9 f 15.7675 2.0804 19.8594 11.6756
B6.A-Chr9 m 15.8363 2.0804 19.9282 11.7443
B6.A-ChrX f 17.4463 2.0804 21.5382 13.3543
B6.A-ChrX m 12.1225 2.0804 16.2144 8.0306
C57BL/6J f 17.8031 1.471 20.6966 14.9097
C57BL/6J m 16.5325 1.471 19.4259 13.6391


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 14.7994 1.0402 16.8453 12.7534
B6.A-Chr1 both 22.6884 1.471 25.5819 19.795
B6.A-Chr10 both 34.5888 1.471 37.4822 31.6953
B6.A-Chr11 both 21.5444 1.471 24.4378 18.6509
B6.A-Chr12 both 21.5512 1.471 24.4447 18.6578
B6.A-Chr13 both 24.8188 1.471 27.7122 21.9253
B6.A-Chr14 both 21.9343 1.471 24.8277 19.0408
B6.A-Chr15 both 16.4433 1.471 19.3367 13.5499
B6.A-Chr16 both 17.6725 1.471 20.5659 14.7791
B6.A-Chr17 both 35.0406 1.471 37.9341 32.1472
B6.A-Chr18 both 25.6619 1.471 28.5553 22.7684
B6.A-Chr19 both 20.8275 1.471 23.7209 17.9341
B6.A-Chr2 both 22.0538 1.4296 24.8657 19.2418
B6.A-Chr3 both 23.4375 1.471 26.3309 20.5441
B6.A-Chr4 both 16.2631 1.471 19.1566 13.3697
B6.A-Chr5 both 15.7506 1.471 18.6441 12.8572
B6.A-Chr6 both 28.3013 1.471 31.1947 25.4078
B6.A-Chr7 both 37.9031 1.471 40.7966 35.0097
B6.A-Chr8 both 26.6313 1.471 29.5247 23.7378
B6.A-Chr9 both 15.8019 1.471 18.6953 12.9084
B6.A-ChrX both 14.7844 1.471 17.6778 11.8909
C57BL/6J both 17.1678 1.0402 19.2138 15.1218




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA