Project measure / variable:   Donahue5   pct_MONO_inflam

ID, description, units MPD:41404   pct_MONO_inflam   inflammatory monocytes (percentage of viable WBC)   [%]  
Data set, strains Donahue5   B6.A consomic w/par   22 strains     sex: both     age: 7wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Donahue5 - inflammatory monocytes (percentage of viable WBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains22 strains
Mean of the strain means4.92   % 6.14   %
Median of the strain means4.49   % 5.83   %
SD of the strain means± 1.75 ± 2.21
Coefficient of variation (CV)0.356 0.360
Min–max range of strain means2.42   –   9.10   % 2.71   –   12.4   %
Mean sample size per strain8.4   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 130.9289 130.9289 44.3641 < 0.0001
strain 21 1441.9883 68.6661 23.2669 < 0.0001
sex:strain 21 85.8914 4.0901 1.3859 0.1215
Residuals 341 1006.3722 2.9512


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 3.32 2.02   16 0.505 0.609 0.91, 6.15 -0.91
A/J m 3.97 2.17   16 0.543 0.547 1.48, 7.33 -0.98
B6.A-Chr1 f 3.25 0.673   8 0.238 0.207 1.92, 4.05 -0.95
B6.A-Chr1 m 4.87 0.507   8 0.179 0.104 4.11, 5.57 -0.58
B6.A-Chr10 f 7.07 2.22   8 0.786 0.314 3.73, 9.8 1.23
B6.A-Chr10 m 7.73 2.78   8 0.983 0.36 3.39, 10.3 0.72
B6.A-Chr11 f 4.56 1.11   8 0.391 0.243 2.95, 6.03 -0.21
B6.A-Chr11 m 6.01 1.52   8 0.537 0.252 4.19, 7.93 -0.06
B6.A-Chr12 f 4.88 1.24   8 0.44 0.255 2.43, 6.21 -0.02
B6.A-Chr12 m 6.86 1.5   8 0.53 0.219 4.56, 9.02 0.32
B6.A-Chr13 f 7.46 1.92   8 0.677 0.257 5.18, 10.7 1.45
B6.A-Chr13 m 7.2 1.16   8 0.409 0.16 5.34, 8.57 0.48
B6.A-Chr14 f 3.78 0.984   8 0.348 0.261 2.63, 5.64 -0.65
B6.A-Chr14 m 4.65 0.514   8 0.182 0.11 3.76, 5.25 -0.67
B6.A-Chr15 f 3.84 1.5   8 0.529 0.39 0.62, 5.14 -0.62
B6.A-Chr15 m 7.23 1.03   8 0.364 0.142 5.98, 9.26 0.49
B6.A-Chr16 f 6.89 2.82   8 0.996 0.409 3.87, 10.4 1.12
B6.A-Chr16 m 7.4 2.65   8 0.938 0.359 4.92, 11.4 0.57
B6.A-Chr17 f 3.05 1.05   8 0.371 0.344 1.12, 4.44 -1.07
B6.A-Chr17 m 4.03 0.728   8 0.257 0.181 2.67, 5.04 -0.95
B6.A-Chr18 f 4.42 1.2   8 0.424 0.271 3.32, 7.12 -0.29
B6.A-Chr18 m 5.82 2.66   8 0.939 0.457 3.13, 10.6 -0.15
B6.A-Chr19 f 5.39 1.16   8 0.411 0.216 3.7, 7.74 0.27
B6.A-Chr19 m 6.32 0.848   8 0.3 0.134 5.05, 7.75 0.08
B6.A-Chr2 f 3.43 0.558   9 0.186 0.163 2.8, 4.59 -0.85
B6.A-Chr2 m 3.82 0.662   8 0.234 0.173 2.86, 4.71 -1.05
B6.A-Chr3 f 7.19 2.06   8 0.73 0.287 4.51, 10.8 1.29
B6.A-Chr3 m 9.8 2.32   8 0.82 0.237 6.72, 12.8 1.65
B6.A-Chr4 f 3.8 0.767   8 0.271 0.202 2.42, 4.55 -0.64
B6.A-Chr4 m 5.82 2.04   8 0.72 0.35 4.29, 10.7 -0.15
B6.A-Chr5 f 3.98 0.926   8 0.327 0.233 2.62, 5.5 -0.54
B6.A-Chr5 m 4.78 1.18   8 0.417 0.247 2.94, 6.59 -0.62
B6.A-Chr6 f 3.76 0.985   8 0.348 0.262 2.26, 5.07 -0.66
B6.A-Chr6 m 4.23 0.784   8 0.277 0.185 3.06, 5.3 -0.86
B6.A-Chr7 f 5.23 1.77   8 0.624 0.337 3.03, 7.87 0.18
B6.A-Chr7 m 5.84 1.62   8 0.571 0.277 3.83, 8.28 -0.14
B6.A-Chr8 f 6.64 1.6   8 0.567 0.242 4.13, 9.21 0.98
B6.A-Chr8 m 8.62 2.68   8 0.948 0.311 3.37, 12.7 1.12
B6.A-Chr9 f 4.83 1.17   8 0.414 0.242 2.31, 6.09 -0.05
B6.A-Chr9 m 5.04 0.863   8 0.305 0.171 3.96, 6.45 -0.5
B6.A-ChrX f 9.1 2.3   8 0.812 0.253 5.41, 12.0 2.38
B6.A-ChrX m 12.4 4.16   8 1.47 0.335 6.53, 17.9 2.83
C57BL/6J f 2.42 1.21   16 0.302 0.499 0.77, 4.64 -1.43
C57BL/6J m 2.71 1.55   16 0.388 0.573 0.45, 5.08 -1.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 3.3162 0.4295 4.161 2.4715
A/J m 3.9731 0.4295 4.8179 3.1284
B6.A-Chr1 f 3.2538 0.6074 4.4484 2.0591
B6.A-Chr1 m 4.8738 0.6074 6.0684 3.6791
B6.A-Chr10 f 7.0713 0.6074 8.2659 5.8766
B6.A-Chr10 m 7.7313 0.6074 8.9259 6.5366
B6.A-Chr11 f 4.5563 0.6074 5.7509 3.3616
B6.A-Chr11 m 6.0125 0.6074 7.2072 4.8178
B6.A-Chr12 f 4.8825 0.6074 6.0772 3.6878
B6.A-Chr12 m 6.8625 0.6074 8.0572 5.6678
B6.A-Chr13 f 7.46 0.6074 8.6547 6.2653
B6.A-Chr13 m 7.2038 0.6074 8.3984 6.0091
B6.A-Chr14 f 3.7763 0.6074 4.9709 2.5816
B6.A-Chr14 m 4.6513 0.6074 5.8459 3.4566
B6.A-Chr15 f 3.8363 0.6074 5.0309 2.6416
B6.A-Chr15 m 7.2313 0.6074 8.4259 6.0366
B6.A-Chr16 f 6.8937 0.6074 8.0884 5.6991
B6.A-Chr16 m 7.3975 0.6074 8.5922 6.2028
B6.A-Chr17 f 3.05 0.6074 4.2447 1.8553
B6.A-Chr17 m 4.0313 0.6074 5.2259 2.8366
B6.A-Chr18 f 4.425 0.6074 5.6197 3.2303
B6.A-Chr18 m 5.8175 0.6074 7.0122 4.6228
B6.A-Chr19 f 5.39 0.6074 6.5847 4.1953
B6.A-Chr19 m 6.3225 0.6074 7.5172 5.1278
B6.A-Chr2 f 3.4289 0.5726 4.5552 2.3025
B6.A-Chr2 m 3.8175 0.6074 5.0122 2.6228
B6.A-Chr3 f 7.1913 0.6074 8.3859 5.9966
B6.A-Chr3 m 9.8 0.6074 10.9947 8.6053
B6.A-Chr4 f 3.7975 0.6074 4.9922 2.6028
B6.A-Chr4 m 5.8225 0.6074 7.0172 4.6278
B6.A-Chr5 f 3.9787 0.6074 5.1734 2.7841
B6.A-Chr5 m 4.7763 0.6074 5.9709 3.5816
B6.A-Chr6 f 3.7575 0.6074 4.9522 2.5628
B6.A-Chr6 m 4.23 0.6074 5.4247 3.0353
B6.A-Chr7 f 5.2337 0.6074 6.4284 4.0391
B6.A-Chr7 m 5.8362 0.6074 7.0309 4.6416
B6.A-Chr8 f 6.635 0.6074 7.8297 5.4403
B6.A-Chr8 m 8.6163 0.6074 9.8109 7.4216
B6.A-Chr9 f 4.8325 0.6074 6.0272 3.6378
B6.A-Chr9 m 5.0438 0.6074 6.2384 3.8491
B6.A-ChrX f 9.0975 0.6074 10.2922 7.9028
B6.A-ChrX m 12.405 0.6074 13.5997 11.2103
C57BL/6J f 2.4206 0.4295 3.2654 1.5759
C57BL/6J m 2.71 0.4295 3.5548 1.8652


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 3.6447 0.3037 4.242 3.0474
B6.A-Chr1 both 4.0638 0.4295 4.9085 3.219
B6.A-Chr10 both 7.4013 0.4295 8.246 6.5565
B6.A-Chr11 both 5.2844 0.4295 6.1291 4.4396
B6.A-Chr12 both 5.8725 0.4295 6.7173 5.0277
B6.A-Chr13 both 7.3319 0.4295 8.1766 6.4871
B6.A-Chr14 both 4.2138 0.4295 5.0585 3.369
B6.A-Chr15 both 5.5338 0.4295 6.3785 4.689
B6.A-Chr16 both 7.1456 0.4295 7.9904 6.3009
B6.A-Chr17 both 3.5406 0.4295 4.3854 2.6959
B6.A-Chr18 both 5.1212 0.4295 5.966 4.2765
B6.A-Chr19 both 5.8563 0.4295 6.701 5.0115
B6.A-Chr2 both 3.6232 0.4174 4.4442 2.8022
B6.A-Chr3 both 8.4956 0.4295 9.3404 7.6509
B6.A-Chr4 both 4.81 0.4295 5.6548 3.9652
B6.A-Chr5 both 4.3775 0.4295 5.2223 3.5327
B6.A-Chr6 both 3.9938 0.4295 4.8385 3.149
B6.A-Chr7 both 5.535 0.4295 6.3798 4.6902
B6.A-Chr8 both 7.6256 0.4295 8.4704 6.7809
B6.A-Chr9 both 4.9381 0.4295 5.7829 4.0934
B6.A-ChrX both 10.7513 0.4295 11.596 9.9065
C57BL/6J both 2.5653 0.3037 3.1626 1.968




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA