Phenotype measure:   Donahue4   distance_center


  STRAIN COMPARISON PLOT
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Donahue4 - distance traveled in center of arena, 10 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means470   cm 514   cm
Median of the strain means477   cm 508   cm
SD of the strain means± 109 ± 114
Coefficient of variation (CV)0.232 0.222
Min–max range of strain means308   –   662   cm 285   –   797   cm
Mean sample size per strain7.8   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 213341.5704 213341.5704 8.4184 0.0039
strain 27 4040571.168 149650.784 5.9052 < 0.0001
sex:strain 27 1160626.8799 42986.1807 1.6962 0.0178
Residuals 371 9401947.7821 25342.1773


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 310.0 79.8   8 28.2 0.258 185.0, 415.0 -1.46
B6.PWD-Chr1 m 285.0 96.2   8 34.0 0.337 177.0, 489.0 -2.01
B6.PWD-Chr10.1 f 525.0 132.0   8 46.7 0.252 392.0, 764.0 0.51
B6.PWD-Chr10.1 m 609.0 192.0   8 67.8 0.315 316.0, 817.0 0.83
B6.PWD-Chr10.2 f 624.0 165.0   8 58.3 0.264 407.0, 811.0 1.42
B6.PWD-Chr10.2 m 551.0 155.0   8 55.0 0.282 327.0, 838.0 0.33
B6.PWD-Chr10.3 f 373.0 149.0   8 52.6 0.399 115.0, 564.0 -0.89
B6.PWD-Chr10.3 m 483.0 112.0   8 39.6 0.232 369.0, 688.0 -0.27
B6.PWD-Chr11.1 f 466.0 67.9   8 24.0 0.146 376.0, 578.0 -0.03
B6.PWD-Chr11.1 m 500.0 131.0   8 46.3 0.261 350.0, 684.0 -0.12
B6.PWD-Chr11.2 f 368.0 140.0   7 53.0 0.38 218.0, 605.0 -0.93
B6.PWD-Chr11.2 m 401.0 94.8   7 35.8 0.237 272.0, 561.0 -0.99
B6.PWD-Chr11.3 f 513.0 225.0   8 79.5 0.438 188.0, 850.0 0.4
B6.PWD-Chr11.3 m 420.0 121.0   8 42.6 0.287 249.0, 605.0 -0.82
B6.PWD-Chr12 f 584.0 264.0   8 93.3 0.452 192.0, 949.0 1.05
B6.PWD-Chr12 m 695.0 133.0   8 47.0 0.191 556.0, 994.0 1.59
B6.PWD-Chr13 f 558.0 184.0   8 65.2 0.33 324.0, 827.0 0.81
B6.PWD-Chr13 m 575.0 200.0   8 70.8 0.348 375.0, 1008.0 0.54
B6.PWD-Chr14 f 593.0 76.5   8 27.0 0.129 487.0, 710.0 1.13
B6.PWD-Chr14 m 647.0 206.0   8 72.9 0.318 309.0, 985.0 1.17
B6.PWD-Chr15 f 550.0 163.0   8 57.6 0.296 231.0, 772.0 0.74
B6.PWD-Chr15 m 504.0 162.0   8 57.2 0.321 302.0, 798.0 -0.09
B6.PWD-Chr16 f 488.0 180.0   8 63.7 0.37 226.0, 823.0 0.17
B6.PWD-Chr16 m 513.0 224.0   8 79.3 0.437 173.0, 729.0 -0.01
B6.PWD-Chr17 f 378.0 115.0   8 40.7 0.304 277.0, 619.0 -0.84
B6.PWD-Chr17 m 397.0 227.0   6 92.9 0.573 201.0, 835.0 -1.02
B6.PWD-Chr18 f 383.0 124.0   8 43.9 0.324 142.0, 526.0 -0.79
B6.PWD-Chr18 m 499.0 188.0   8 66.4 0.376 215.0, 780.0 -0.13
B6.PWD-Chr19 f 348.0 96.9   8 34.3 0.278 233.0, 547.0 -1.11
B6.PWD-Chr19 m 612.0 134.0   7 50.7 0.219 470.0, 804.0 0.86
B6.PWD-Chr2 f 465.0 177.0   8 62.6 0.381 186.0, 713.0 -0.04
B6.PWD-Chr2 m 390.0 164.0   8 58.1 0.421 125.0, 645.0 -1.09
B6.PWD-Chr3 f 570.0 188.0   8 66.6 0.33 267.0, 801.0 0.92
B6.PWD-Chr3 m 538.0 116.0   3 66.8 0.215 454.0, 670.0 0.21
B6.PWD-Chr5 f 335.0 123.0   8 43.4 0.366 163.0, 524.0 -1.23
B6.PWD-Chr5 m 423.0 108.0   8 38.1 0.255 252.0, 572.0 -0.8
B6.PWD-Chr6 f 312.0 99.7   8 35.3 0.32 187.0, 499.0 -1.44
B6.PWD-Chr6 m 452.0 170.0   8 60.0 0.376 173.0, 681.0 -0.54
B6.PWD-Chr8 f 423.0 212.0   5 94.6 0.5 140.0, 683.0 -0.43
B6.PWD-Chr8 m 551.0 206.0   6 84.3 0.375 190.0, 770.0 0.33
B6.PWD-Chr9 f 525.0 149.0   8 52.5 0.283 234.0, 702.0 0.51
B6.PWD-Chr9 m 797.0 267.0   8 94.3 0.335 403.0, 1073.0 2.48
B6.PWD-ChrX.1 f 662.0 169.0   6 69.1 0.256 477.0, 953.0 1.76
B6.PWD-ChrX.1 m 600.0 173.0   8 61.3 0.289 308.0, 802.0 0.76
B6.PWD-ChrX.2 f 624.0 155.0   8 55.0 0.249 391.0, 936.0 1.42
B6.PWD-ChrX.2 m 399.0 156.0   7 58.9 0.391 235.0, 706.0 -1.01
B6.PWD-ChrX.3 f 341.0 125.0   8 44.3 0.367 226.0, 591.0 -1.18
B6.PWD-ChrX.3 m 461.0 118.0   8 41.8 0.256 332.0, 679.0 -0.46
B6.PWD-ChrY f 443.0 112.0   7 42.2 0.252 307.0, 623.0 -0.24
B6.PWD-ChrY m 523.0 110.0   7 41.5 0.21 376.0, 680.0 0.08
B6.PWD-mt f 567.0 131.0   8 46.4 0.232 366.0, 759.0 0.89
B6.PWD-mt m 566.0 195.0   8 68.9 0.344 221.0, 824.0 0.46
C57BL/6J f 513.0 167.0   8 59.2 0.326 355.0, 889.0 0.4
C57BL/6J m 659.0 140.0   8 49.6 0.213 531.0, 934.0 1.27
PWD/PhJ f 308.0 169.0   7 64.0 0.551 36.0, 451.0 -1.48
PWD/PhJ m 338.0 139.0   8 49.0 0.41 142.0, 561.0 -1.54


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 309.5 56.283 420.1736 198.8264
B6.PWD-Chr1 m 285.125 56.283 395.7986 174.4514
B6.PWD-Chr10.1 f 525.375 56.283 636.0486 414.7014
B6.PWD-Chr10.1 m 609.125 56.283 719.7986 498.4514
B6.PWD-Chr10.2 f 624.5 56.283 735.1736 513.8264
B6.PWD-Chr10.2 m 550.625 56.283 661.2986 439.9514
B6.PWD-Chr10.3 f 372.75 56.283 483.4236 262.0764
B6.PWD-Chr10.3 m 483.125 56.283 593.7986 372.4514
B6.PWD-Chr11.1 f 466.5 56.283 577.1736 355.8264
B6.PWD-Chr11.1 m 500.5 56.283 611.1736 389.8264
B6.PWD-Chr11.2 f 368.4286 60.169 486.7437 250.1135
B6.PWD-Chr11.2 m 400.5714 60.169 518.8865 282.2563
B6.PWD-Chr11.3 f 512.625 56.283 623.2986 401.9514
B6.PWD-Chr11.3 m 420.5 56.283 531.1736 309.8264
B6.PWD-Chr12 f 584.25 56.283 694.9236 473.5764
B6.PWD-Chr12 m 695.0 56.283 805.6736 584.3264
B6.PWD-Chr13 f 558.5 56.283 669.1736 447.8264
B6.PWD-Chr13 m 575.125 56.283 685.7986 464.4514
B6.PWD-Chr14 f 593.375 56.283 704.0486 482.7014
B6.PWD-Chr14 m 647.375 56.283 758.0486 536.7014
B6.PWD-Chr15 f 550.125 56.283 660.7986 439.4514
B6.PWD-Chr15 m 504.0 56.283 614.6736 393.3264
B6.PWD-Chr16 f 487.875 56.283 598.5486 377.2014
B6.PWD-Chr16 m 513.0 56.283 623.6736 402.3264
B6.PWD-Chr17 f 378.125 56.283 488.7986 267.4514
B6.PWD-Chr17 m 397.1667 64.99 524.9616 269.3718
B6.PWD-Chr18 f 382.75 56.283 493.4236 272.0764
B6.PWD-Chr18 m 499.25 56.283 609.9236 388.5764
B6.PWD-Chr19 f 348.375 56.283 459.0486 237.7014
B6.PWD-Chr19 m 611.7143 60.169 730.0294 493.3992
B6.PWD-Chr2 f 465.25 56.283 575.9236 354.5764
B6.PWD-Chr2 m 390.0 56.283 500.6736 279.3264
B6.PWD-Chr3 f 570.375 56.283 681.0486 459.7014
B6.PWD-Chr3 m 538.0 91.9097 718.7293 357.2707
B6.PWD-Chr5 f 335.0 56.283 445.6736 224.3264
B6.PWD-Chr5 m 422.75 56.283 533.4236 312.0764
B6.PWD-Chr6 f 311.5 56.283 422.1736 200.8264
B6.PWD-Chr6 m 451.5 56.283 562.1736 340.8264
B6.PWD-Chr8 f 423.2 71.1929 563.1923 283.2077
B6.PWD-Chr8 m 550.8333 64.99 678.6282 423.0384
B6.PWD-Chr9 f 525.0 56.283 635.6736 414.3264
B6.PWD-Chr9 m 796.875 56.283 907.5486 686.2014
B6.PWD-ChrX.1 f 661.6667 64.99 789.4616 533.8718
B6.PWD-ChrX.1 m 599.5 56.283 710.1736 488.8264
B6.PWD-ChrX.2 f 624.5 56.283 735.1736 513.8264
B6.PWD-ChrX.2 m 398.7143 60.169 517.0294 280.3992
B6.PWD-ChrX.3 f 341.125 56.283 451.7986 230.4514
B6.PWD-ChrX.3 m 461.0 56.283 571.6736 350.3264
B6.PWD-ChrY f 442.7143 60.169 561.0294 324.3992
B6.PWD-ChrY m 522.5714 60.169 640.8865 404.2563
B6.PWD-mt f 566.625 56.283 677.2986 455.9514
B6.PWD-mt m 566.0 56.283 676.6736 455.3264
C57BL/6J f 512.75 56.283 623.4236 402.0764
C57BL/6J m 659.375 56.283 770.0486 548.7014
PWD/PhJ f 307.7143 60.169 426.0294 189.3992
PWD/PhJ m 337.625 56.283 448.2986 226.9514


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 297.3125 39.7981 375.5706 219.0544
B6.PWD-Chr10.1 both 567.25 39.7981 645.5081 488.9919
B6.PWD-Chr10.2 both 587.5625 39.7981 665.8206 509.3044
B6.PWD-Chr10.3 both 427.9375 39.7981 506.1956 349.6794
B6.PWD-Chr11.1 both 483.5 39.7981 561.7581 405.2419
B6.PWD-Chr11.2 both 384.5 42.5459 468.1614 300.8386
B6.PWD-Chr11.3 both 466.5625 39.7981 544.8206 388.3044
B6.PWD-Chr12 both 639.625 39.7981 717.8831 561.3669
B6.PWD-Chr13 both 566.8125 39.7981 645.0706 488.5544
B6.PWD-Chr14 both 620.375 39.7981 698.6331 542.1169
B6.PWD-Chr15 both 527.0625 39.7981 605.3206 448.8044
B6.PWD-Chr16 both 500.4375 39.7981 578.6956 422.1794
B6.PWD-Chr17 both 387.6458 42.9868 472.1742 303.1175
B6.PWD-Chr18 both 441.0 39.7981 519.2581 362.7419
B6.PWD-Chr19 both 480.0446 41.1949 561.0494 399.0398
B6.PWD-Chr2 both 427.625 39.7981 505.8831 349.3669
B6.PWD-Chr3 both 554.1875 53.8868 660.1494 448.2256
B6.PWD-Chr5 both 378.875 39.7981 457.1331 300.6169
B6.PWD-Chr6 both 381.5 39.7981 459.7581 303.2419
B6.PWD-Chr8 both 487.0167 48.1979 581.7919 392.2414
B6.PWD-Chr9 both 660.9375 39.7981 739.1956 582.6794
B6.PWD-ChrX.1 both 630.5833 42.9868 715.1117 546.055
B6.PWD-ChrX.2 both 511.6071 41.1949 592.6119 430.6023
B6.PWD-ChrX.3 both 401.0625 39.7981 479.3206 322.8044
B6.PWD-ChrY both 482.6429 42.5459 566.3043 398.9815
B6.PWD-mt both 566.3125 39.7981 644.5706 488.0544
C57BL/6J both 586.0625 39.7981 664.3206 507.8044
PWD/PhJ both 322.6696 41.1949 403.6744 241.6648




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA