Phenotype measure:   Donahue4   duration_vert


  STRAIN COMPARISON PLOT
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Donahue4 - duration of total vertical activity, 10 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means50.6   s 57.9   s
Median of the strain means50.8   s 56.9   s
SD of the strain means± 14.6 ± 12.2
Coefficient of variation (CV)0.288 0.211
Min–max range of strain means11.8   –   88.4   s 40.6   –   88.2   s
Mean sample size per strain7.8   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4835.2217 4835.2217 19.7069 < 0.0001
strain 27 60095.1655 2225.7469 9.0715 < 0.0001
sex:strain 27 11798.6425 436.9868 1.781 0.0106
Residuals 371 91027.3746 245.3568


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 40.9 11.6   8 4.09 0.282 25.5, 56.6 -0.66
B6.PWD-Chr1 m 40.6 14.0   8 4.96 0.346 18.6, 54.2 -1.41
B6.PWD-Chr10.1 f 45.8 7.85   8 2.77 0.171 35.9, 59.0 -0.33
B6.PWD-Chr10.1 m 57.4 12.6   8 4.46 0.219 38.4, 77.7 -0.04
B6.PWD-Chr10.2 f 55.9 16.5   8 5.83 0.295 31.7, 87.0 0.37
B6.PWD-Chr10.2 m 66.6 5.78   8 2.04 0.0867 57.9, 76.3 0.71
B6.PWD-Chr10.3 f 42.4 13.1   8 4.63 0.309 26.5, 58.7 -0.56
B6.PWD-Chr10.3 m 45.6 8.19   8 2.9 0.18 28.7, 56.2 -1.0
B6.PWD-Chr11.1 f 51.9 15.9   8 5.63 0.307 36.3, 82.2 0.09
B6.PWD-Chr11.1 m 59.0 18.4   8 6.51 0.312 37.6, 90.3 0.09
B6.PWD-Chr11.2 f 42.5 12.5   7 4.74 0.295 28.8, 62.3 -0.55
B6.PWD-Chr11.2 m 45.0 12.1   7 4.58 0.269 28.1, 59.1 -1.05
B6.PWD-Chr11.3 f 39.4 12.7   8 4.51 0.324 20.8, 61.5 -0.77
B6.PWD-Chr11.3 m 47.7 14.2   8 5.02 0.298 29.1, 71.0 -0.83
B6.PWD-Chr12 f 39.3 13.0   8 4.59 0.33 21.2, 62.7 -0.77
B6.PWD-Chr12 m 40.8 9.01   8 3.19 0.221 28.3, 58.1 -1.4
B6.PWD-Chr13 f 77.1 17.9   8 6.32 0.232 55.7, 99.6 1.82
B6.PWD-Chr13 m 88.2 24.4   8 8.63 0.277 55.7, 133.0 2.48
B6.PWD-Chr14 f 53.7 20.1   8 7.1 0.374 32.7, 96.6 0.22
B6.PWD-Chr14 m 60.8 8.31   8 2.94 0.137 50.0, 74.8 0.24
B6.PWD-Chr15 f 52.4 15.4   8 5.43 0.293 29.7, 82.0 0.13
B6.PWD-Chr15 m 47.0 15.4   8 5.44 0.328 24.4, 68.8 -0.89
B6.PWD-Chr16 f 54.5 14.8   8 5.23 0.272 36.1, 80.4 0.27
B6.PWD-Chr16 m 52.7 18.4   8 6.49 0.348 29.3, 83.8 -0.42
B6.PWD-Chr17 f 48.9 6.86   8 2.43 0.14 41.7, 59.6 -0.11
B6.PWD-Chr17 m 45.9 7.41   6 3.02 0.162 34.8, 52.9 -0.98
B6.PWD-Chr18 f 60.4 11.6   8 4.1 0.192 43.8, 73.0 0.68
B6.PWD-Chr18 m 64.4 8.0   8 2.83 0.124 56.7, 77.0 0.53
B6.PWD-Chr19 f 49.8 19.5   8 6.89 0.391 24.3, 87.1 -0.05
B6.PWD-Chr19 m 71.8 22.5   7 8.5 0.313 50.3, 98.7 1.14
B6.PWD-Chr2 f 88.4 20.1   8 7.1 0.227 58.4, 125.0 2.6
B6.PWD-Chr2 m 77.0 27.2   8 9.61 0.353 15.9, 103.0 1.57
B6.PWD-Chr3 f 56.1 19.0   8 6.73 0.339 21.2, 79.0 0.38
B6.PWD-Chr3 m 79.8 23.8   3 13.7 0.298 55.6, 103.0 1.8
B6.PWD-Chr5 f 36.9 10.7   8 3.79 0.291 22.7, 53.2 -0.94
B6.PWD-Chr5 m 55.8 15.6   8 5.53 0.28 31.3, 84.8 -0.17
B6.PWD-Chr6 f 38.4 27.1   8 9.57 0.705 5.1, 94.8 -0.84
B6.PWD-Chr6 m 58.2 18.6   8 6.58 0.32 29.8, 91.0 0.03
B6.PWD-Chr8 f 35.1 18.0   5 8.04 0.512 8.0, 52.3 -1.06
B6.PWD-Chr8 m 43.8 18.1   6 7.39 0.413 22.4, 65.7 -1.15
B6.PWD-Chr9 f 49.5 13.8   8 4.88 0.279 29.1, 69.6 -0.07
B6.PWD-Chr9 m 64.8 14.7   8 5.2 0.227 43.5, 87.1 0.57
B6.PWD-ChrX.1 f 61.7 8.16   6 3.33 0.132 47.5, 73.0 0.76
B6.PWD-ChrX.1 m 52.0 14.0   8 4.94 0.269 33.7, 75.5 -0.48
B6.PWD-ChrX.2 f 60.3 15.4   8 5.45 0.256 38.4, 80.1 0.67
B6.PWD-ChrX.2 m 57.3 5.98   7 2.26 0.104 52.0, 66.5 -0.05
B6.PWD-ChrX.3 f 37.4 8.88   8 3.14 0.237 24.5, 51.9 -0.9
B6.PWD-ChrX.3 m 56.3 16.6   8 5.87 0.295 36.1, 84.7 -0.13
B6.PWD-ChrY f 63.1 13.5   7 5.11 0.214 34.3, 73.5 0.86
B6.PWD-ChrY m 63.5 13.5   7 5.09 0.212 47.8, 86.1 0.46
B6.PWD-mt f 56.1 6.78   8 2.4 0.121 49.2, 69.7 0.38
B6.PWD-mt m 56.5 15.3   8 5.39 0.27 32.8, 84.8 -0.11
C57BL/6J f 66.2 13.0   8 4.6 0.197 49.1, 89.7 1.07
C57BL/6J m 73.2 20.3   8 7.18 0.278 49.3, 108.0 1.26
PWD/PhJ f 11.8 15.0   7 5.66 1.27 0.3, 41.4 -2.66
PWD/PhJ m 48.5 27.7   8 9.78 0.57 3.8, 98.8 -0.77


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 40.9125 5.538 51.8023 30.0227
B6.PWD-Chr1 m 40.625 5.538 51.5148 29.7352
B6.PWD-Chr10.1 f 45.7875 5.538 56.6773 34.8977
B6.PWD-Chr10.1 m 57.4375 5.538 68.3273 46.5477
B6.PWD-Chr10.2 f 55.8625 5.538 66.7523 44.9727
B6.PWD-Chr10.2 m 66.575 5.538 77.4648 55.6852
B6.PWD-Chr10.3 f 42.35 5.538 53.2398 31.4602
B6.PWD-Chr10.3 m 45.625 5.538 56.5148 34.7352
B6.PWD-Chr11.1 f 51.85 5.538 62.7398 40.9602
B6.PWD-Chr11.1 m 59.0 5.538 69.8898 48.1102
B6.PWD-Chr11.2 f 42.4571 5.9204 54.0989 30.8154
B6.PWD-Chr11.2 m 45.0 5.9204 56.6417 33.3583
B6.PWD-Chr11.3 f 39.375 5.538 50.2648 28.4852
B6.PWD-Chr11.3 m 47.6625 5.538 58.5523 36.7727
B6.PWD-Chr12 f 39.325 5.538 50.2148 28.4352
B6.PWD-Chr12 m 40.775 5.538 51.6648 29.8852
B6.PWD-Chr13 f 77.0875 5.538 87.9773 66.1977
B6.PWD-Chr13 m 88.175 5.538 99.0648 77.2852
B6.PWD-Chr14 f 53.675 5.538 64.5648 42.7852
B6.PWD-Chr14 m 60.825 5.538 71.7148 49.9352
B6.PWD-Chr15 f 52.35 5.538 63.2398 41.4602
B6.PWD-Chr15 m 46.975 5.538 57.8648 36.0852
B6.PWD-Chr16 f 54.4875 5.538 65.3773 43.5977
B6.PWD-Chr16 m 52.725 5.538 63.6148 41.8352
B6.PWD-Chr17 f 48.9375 5.538 59.8273 38.0477
B6.PWD-Chr17 m 45.8667 6.3947 58.4412 33.2922
B6.PWD-Chr18 f 60.4375 5.538 71.3273 49.5477
B6.PWD-Chr18 m 64.3875 5.538 75.2773 53.4977
B6.PWD-Chr19 f 49.825 5.538 60.7148 38.9352
B6.PWD-Chr19 m 71.7571 5.9204 83.3989 60.1154
B6.PWD-Chr2 f 88.45 5.538 99.3398 77.5602
B6.PWD-Chr2 m 77.0375 5.538 87.9273 66.1477
B6.PWD-Chr3 f 56.15 5.538 67.0398 45.2602
B6.PWD-Chr3 m 79.8333 9.0435 97.6164 62.0503
B6.PWD-Chr5 f 36.9125 5.538 47.8023 26.0227
B6.PWD-Chr5 m 55.8 5.538 66.6898 44.9102
B6.PWD-Chr6 f 38.3875 5.538 49.2773 27.4977
B6.PWD-Chr6 m 58.1875 5.538 69.0773 47.2977
B6.PWD-Chr8 f 35.1 7.0051 48.8747 21.3253
B6.PWD-Chr8 m 43.8333 6.3947 56.4078 31.2588
B6.PWD-Chr9 f 49.4875 5.538 60.3773 38.5977
B6.PWD-Chr9 m 64.825 5.538 75.7148 53.9352
B6.PWD-ChrX.1 f 61.7 6.3947 74.2745 49.1255
B6.PWD-ChrX.1 m 52.025 5.538 62.9148 41.1352
B6.PWD-ChrX.2 f 60.3 5.538 71.1898 49.4102
B6.PWD-ChrX.2 m 57.3 5.9204 68.9417 45.6583
B6.PWD-ChrX.3 f 37.4 5.538 48.2898 26.5102
B6.PWD-ChrX.3 m 56.275 5.538 67.1648 45.3852
B6.PWD-ChrY f 63.0714 5.9204 74.7132 51.4297
B6.PWD-ChrY m 63.5429 5.9204 75.1846 51.9011
B6.PWD-mt f 56.0625 5.538 66.9523 45.1727
B6.PWD-mt m 56.45 5.538 67.3398 45.5602
C57BL/6J f 66.1875 5.538 77.0773 55.2977
C57BL/6J m 73.1875 5.538 84.0773 62.2977
PWD/PhJ f 11.7714 5.9204 23.4132 0.1297
PWD/PhJ m 48.5125 5.538 59.4023 37.6227


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 40.7687 3.916 48.469 33.0685
B6.PWD-Chr10.1 both 51.6125 3.916 59.3128 43.9122
B6.PWD-Chr10.2 both 61.2188 3.916 68.919 53.5185
B6.PWD-Chr10.3 both 43.9875 3.916 51.6878 36.2872
B6.PWD-Chr11.1 both 55.425 3.916 63.1253 47.7247
B6.PWD-Chr11.2 both 43.7286 4.1863 51.9605 35.4966
B6.PWD-Chr11.3 both 43.5187 3.916 51.219 35.8185
B6.PWD-Chr12 both 40.05 3.916 47.7503 32.3497
B6.PWD-Chr13 both 82.6312 3.916 90.3315 74.931
B6.PWD-Chr14 both 57.25 3.916 64.9503 49.5497
B6.PWD-Chr15 both 49.6625 3.916 57.3628 41.9622
B6.PWD-Chr16 both 53.6063 3.916 61.3065 45.906
B6.PWD-Chr17 both 47.4021 4.2297 55.7193 39.0848
B6.PWD-Chr18 both 62.4125 3.916 70.1128 54.7122
B6.PWD-Chr19 both 60.7911 4.0534 68.7616 52.8205
B6.PWD-Chr2 both 82.7438 3.916 90.444 75.0435
B6.PWD-Chr3 both 67.9917 5.3022 78.4179 57.5654
B6.PWD-Chr5 both 46.3562 3.916 54.0565 38.656
B6.PWD-Chr6 both 48.2875 3.916 55.9878 40.5872
B6.PWD-Chr8 both 39.4667 4.7425 48.7922 30.1412
B6.PWD-Chr9 both 57.1562 3.916 64.8565 49.456
B6.PWD-ChrX.1 both 56.8625 4.2297 65.1797 48.5453
B6.PWD-ChrX.2 both 58.8 4.0534 66.7705 50.8295
B6.PWD-ChrX.3 both 46.8375 3.916 54.5378 39.1372
B6.PWD-ChrY both 63.3071 4.1863 71.5391 55.0752
B6.PWD-mt both 56.2562 3.916 63.9565 48.556
C57BL/6J both 69.6875 3.916 77.3878 61.9872
PWD/PhJ both 30.142 4.0534 38.1125 22.1714




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA