Phenotype measure:   Donahue4   episode_vert


  STRAIN COMPARISON PLOT
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Donahue4 - number of discrete vertical episodes, 10 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means54.6   n 58.3   n
Median of the strain means52.8   n 56.6   n
SD of the strain means± 14.2 ± 11.4
Coefficient of variation (CV)0.259 0.196
Min–max range of strain means16.3   –   88.8   n 36.8   –   83.2   n
Mean sample size per strain7.8   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1211.3287 1211.3287 6.2662 0.0127
strain 27 58010.0643 2148.5209 11.1142 < 0.0001
sex:strain 27 8896.2522 329.4908 1.7044 0.017
Residuals 371 71718.9262 193.3125


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 37.8 11.1   8 3.94 0.295 26.0, 55.0 -1.19
B6.PWD-Chr1 m 36.8 9.59   8 3.39 0.261 22.0, 47.0 -1.88
B6.PWD-Chr10.1 f 54.2 11.5   8 4.07 0.212 38.0, 69.0 -0.03
B6.PWD-Chr10.1 m 64.4 12.4   8 4.4 0.193 47.0, 82.0 0.53
B6.PWD-Chr10.2 f 65.0 16.1   8 5.68 0.247 37.0, 85.0 0.73
B6.PWD-Chr10.2 m 73.0 14.5   8 5.13 0.199 55.0, 90.0 1.29
B6.PWD-Chr10.3 f 48.9 11.9   8 4.2 0.243 33.0, 64.0 -0.41
B6.PWD-Chr10.3 m 53.0 9.3   8 3.29 0.176 34.0, 62.0 -0.46
B6.PWD-Chr11.1 f 50.0 11.4   8 4.02 0.228 34.0, 70.0 -0.33
B6.PWD-Chr11.1 m 57.2 11.6   8 4.1 0.203 38.0, 78.0 -0.09
B6.PWD-Chr11.2 f 40.9 12.8   7 4.84 0.313 28.0, 61.0 -0.97
B6.PWD-Chr11.2 m 41.6 8.83   7 3.34 0.212 27.0, 53.0 -1.46
B6.PWD-Chr11.3 f 47.1 8.82   8 3.12 0.187 39.0, 65.0 -0.53
B6.PWD-Chr11.3 m 51.8 15.2   8 5.37 0.294 34.0, 73.0 -0.57
B6.PWD-Chr12 f 52.5 17.4   8 6.14 0.331 29.0, 87.0 -0.15
B6.PWD-Chr12 m 53.6 9.32   8 3.29 0.174 41.0, 67.0 -0.41
B6.PWD-Chr13 f 78.2 12.8   8 4.53 0.164 62.0, 98.0 1.66
B6.PWD-Chr13 m 83.2 14.1   8 4.97 0.169 56.0, 102.0 2.18
B6.PWD-Chr14 f 53.0 20.7   8 7.33 0.391 27.0, 97.0 -0.12
B6.PWD-Chr14 m 60.9 17.0   8 6.02 0.28 43.0, 98.0 0.23
B6.PWD-Chr15 f 56.1 13.9   8 4.9 0.247 36.0, 72.0 0.1
B6.PWD-Chr15 m 53.1 13.6   8 4.79 0.255 30.0, 71.0 -0.45
B6.PWD-Chr16 f 51.6 12.5   8 4.41 0.242 37.0, 75.0 -0.22
B6.PWD-Chr16 m 53.4 13.8   8 4.9 0.259 33.0, 75.0 -0.43
B6.PWD-Chr17 f 49.6 4.69   8 1.66 0.0945 44.0, 58.0 -0.36
B6.PWD-Chr17 m 42.8 7.7   6 3.15 0.18 33.0, 53.0 -1.35
B6.PWD-Chr18 f 64.1 16.2   8 5.72 0.252 47.0, 96.0 0.67
B6.PWD-Chr18 m 61.8 10.4   8 3.67 0.168 47.0, 73.0 0.31
B6.PWD-Chr19 f 47.9 14.4   8 5.09 0.301 24.0, 62.0 -0.48
B6.PWD-Chr19 m 64.9 12.9   7 4.88 0.199 49.0, 80.0 0.58
B6.PWD-Chr2 f 88.8 8.14   8 2.88 0.0917 79.0, 102.0 2.41
B6.PWD-Chr2 m 72.6 21.2   8 7.49 0.292 27.0, 98.0 1.25
B6.PWD-Chr3 f 66.5 16.5   8 5.84 0.248 32.0, 84.0 0.84
B6.PWD-Chr3 m 75.7 13.0   3 7.51 0.172 63.0, 89.0 1.52
B6.PWD-Chr5 f 42.2 7.48   8 2.64 0.177 29.0, 52.0 -0.88
B6.PWD-Chr5 m 56.0 15.6   8 5.53 0.279 33.0, 78.0 -0.2
B6.PWD-Chr6 f 42.1 24.6   8 8.7 0.584 6.0, 88.0 -0.89
B6.PWD-Chr6 m 57.5 17.4   8 6.16 0.303 36.0, 84.0 -0.07
B6.PWD-Chr8 f 51.6 18.8   5 8.41 0.364 20.0, 70.0 -0.22
B6.PWD-Chr8 m 51.0 10.2   6 4.16 0.2 38.0, 63.0 -0.64
B6.PWD-Chr9 f 63.5 18.1   8 6.41 0.285 35.0, 86.0 0.63
B6.PWD-Chr9 m 75.1 17.4   8 6.15 0.231 51.0, 105.0 1.47
B6.PWD-ChrX.1 f 67.7 12.4   6 5.06 0.183 49.0, 87.0 0.92
B6.PWD-ChrX.1 m 54.1 13.8   8 4.89 0.256 38.0, 71.0 -0.37
B6.PWD-ChrX.2 f 63.1 10.1   8 3.57 0.16 51.0, 78.0 0.6
B6.PWD-ChrX.2 m 53.3 8.12   7 3.07 0.152 42.0, 67.0 -0.44
B6.PWD-ChrX.3 f 38.1 8.76   8 3.1 0.23 27.0, 49.0 -1.17
B6.PWD-ChrX.3 m 52.2 13.5   8 4.76 0.258 33.0, 74.0 -0.53
B6.PWD-ChrY f 65.3 16.4   7 6.19 0.251 42.0, 90.0 0.75
B6.PWD-ChrY m 63.7 11.2   7 4.25 0.176 50.0, 79.0 0.47
B6.PWD-mt f 64.6 12.7   8 4.48 0.196 52.0, 93.0 0.7
B6.PWD-mt m 58.6 12.7   8 4.48 0.216 44.0, 78.0 0.03
C57BL/6J f 63.4 13.1   8 4.65 0.207 41.0, 80.0 0.62
C57BL/6J m 71.0 14.9   8 5.26 0.21 50.0, 92.0 1.11
PWD/PhJ f 16.3 16.1   7 6.07 0.987 1.0, 41.0 -2.71
PWD/PhJ m 39.6 18.5   8 6.55 0.467 3.0, 60.0 -1.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 37.75 4.9157 47.4161 28.0839
B6.PWD-Chr1 m 36.75 4.9157 46.4161 27.0839
B6.PWD-Chr10.1 f 54.25 4.9157 63.9161 44.5839
B6.PWD-Chr10.1 m 64.375 4.9157 74.0411 54.7089
B6.PWD-Chr10.2 f 65.0 4.9157 74.6661 55.3339
B6.PWD-Chr10.2 m 73.0 4.9157 82.6661 63.3339
B6.PWD-Chr10.3 f 48.875 4.9157 58.5411 39.2089
B6.PWD-Chr10.3 m 53.0 4.9157 62.6661 43.3339
B6.PWD-Chr11.1 f 50.0 4.9157 59.6661 40.3339
B6.PWD-Chr11.1 m 57.25 4.9157 66.9161 47.5839
B6.PWD-Chr11.2 f 40.8571 5.2551 51.1907 30.5236
B6.PWD-Chr11.2 m 41.5714 5.2551 51.9049 31.2379
B6.PWD-Chr11.3 f 47.125 4.9157 56.7911 37.4589
B6.PWD-Chr11.3 m 51.75 4.9157 61.4161 42.0839
B6.PWD-Chr12 f 52.5 4.9157 62.1661 42.8339
B6.PWD-Chr12 m 53.625 4.9157 63.2911 43.9589
B6.PWD-Chr13 f 78.25 4.9157 87.9161 68.5839
B6.PWD-Chr13 m 83.25 4.9157 92.9161 73.5839
B6.PWD-Chr14 f 53.0 4.9157 62.6661 43.3339
B6.PWD-Chr14 m 60.875 4.9157 70.5411 51.2089
B6.PWD-Chr15 f 56.125 4.9157 65.7911 46.4589
B6.PWD-Chr15 m 53.125 4.9157 62.7911 43.4589
B6.PWD-Chr16 f 51.625 4.9157 61.2911 41.9589
B6.PWD-Chr16 m 53.375 4.9157 63.0411 43.7089
B6.PWD-Chr17 f 49.625 4.9157 59.2911 39.9589
B6.PWD-Chr17 m 42.8333 5.6762 53.9948 31.6719
B6.PWD-Chr18 f 64.125 4.9157 73.7911 54.4589
B6.PWD-Chr18 m 61.75 4.9157 71.4161 52.0839
B6.PWD-Chr19 f 47.875 4.9157 57.5411 38.2089
B6.PWD-Chr19 m 64.8571 5.2551 75.1907 54.5236
B6.PWD-Chr2 f 88.75 4.9157 98.4161 79.0839
B6.PWD-Chr2 m 72.625 4.9157 82.2911 62.9589
B6.PWD-Chr3 f 66.5 4.9157 76.1661 56.8339
B6.PWD-Chr3 m 75.6667 8.0273 91.4514 59.882
B6.PWD-Chr5 f 42.25 4.9157 51.9161 32.5839
B6.PWD-Chr5 m 56.0 4.9157 65.6661 46.3339
B6.PWD-Chr6 f 42.125 4.9157 51.7911 32.4589
B6.PWD-Chr6 m 57.5 4.9157 67.1661 47.8339
B6.PWD-Chr8 f 51.6 6.2179 63.8268 39.3732
B6.PWD-Chr8 m 51.0 5.6762 62.1615 39.8385
B6.PWD-Chr9 f 63.5 4.9157 73.1661 53.8339
B6.PWD-Chr9 m 75.125 4.9157 84.7911 65.4589
B6.PWD-ChrX.1 f 67.6667 5.6762 78.8281 56.5052
B6.PWD-ChrX.1 m 54.125 4.9157 63.7911 44.4589
B6.PWD-ChrX.2 f 63.125 4.9157 72.7911 53.4589
B6.PWD-ChrX.2 m 53.2857 5.2551 63.6192 42.9522
B6.PWD-ChrX.3 f 38.125 4.9157 47.7911 28.4589
B6.PWD-ChrX.3 m 52.25 4.9157 61.9161 42.5839
B6.PWD-ChrY f 65.2857 5.2551 75.6192 54.9522
B6.PWD-ChrY m 63.7143 5.2551 74.0478 53.3808
B6.PWD-mt f 64.625 4.9157 74.2911 54.9589
B6.PWD-mt m 58.625 4.9157 68.2911 48.9589
C57BL/6J f 63.375 4.9157 73.0411 53.7089
C57BL/6J m 71.0 4.9157 80.6661 61.3339
PWD/PhJ f 16.2857 5.2551 26.6192 5.9522
PWD/PhJ m 39.625 4.9157 49.2911 29.9589


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 37.25 3.4759 44.085 30.415
B6.PWD-Chr10.1 both 59.3125 3.4759 66.1475 52.4775
B6.PWD-Chr10.2 both 69.0 3.4759 75.835 62.165
B6.PWD-Chr10.3 both 50.9375 3.4759 57.7725 44.1025
B6.PWD-Chr11.1 both 53.625 3.4759 60.46 46.79
B6.PWD-Chr11.2 both 41.2143 3.7159 48.5212 33.9074
B6.PWD-Chr11.3 both 49.4375 3.4759 56.2725 42.6025
B6.PWD-Chr12 both 53.0625 3.4759 59.8975 46.2275
B6.PWD-Chr13 both 80.75 3.4759 87.585 73.915
B6.PWD-Chr14 both 56.9375 3.4759 63.7725 50.1025
B6.PWD-Chr15 both 54.625 3.4759 61.46 47.79
B6.PWD-Chr16 both 52.5 3.4759 59.335 45.665
B6.PWD-Chr17 both 46.2292 3.7544 53.6118 38.8465
B6.PWD-Chr18 both 62.9375 3.4759 69.7725 56.1025
B6.PWD-Chr19 both 56.3661 3.5979 63.4409 49.2912
B6.PWD-Chr2 both 80.6875 3.4759 87.5225 73.8525
B6.PWD-Chr3 both 71.0833 4.7064 80.3379 61.8287
B6.PWD-Chr5 both 49.125 3.4759 55.96 42.29
B6.PWD-Chr6 both 49.8125 3.4759 56.6475 42.9775
B6.PWD-Chr8 both 51.3 4.2095 59.5776 43.0224
B6.PWD-Chr9 both 69.3125 3.4759 76.1475 62.4775
B6.PWD-ChrX.1 both 60.8958 3.7544 68.2785 53.5132
B6.PWD-ChrX.2 both 58.2054 3.5979 65.2802 51.1305
B6.PWD-ChrX.3 both 45.1875 3.4759 52.0225 38.3525
B6.PWD-ChrY both 64.5 3.7159 71.8069 57.1931
B6.PWD-mt both 61.625 3.4759 68.46 54.79
C57BL/6J both 67.1875 3.4759 74.0225 60.3525
PWD/PhJ both 27.9554 3.5979 35.0302 20.8805




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA