Phenotype measure:   Donahue4   breaks_vert


  STRAIN COMPARISON PLOT
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Donahue4 - total number of vertical beam breaks, 10 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means107   n 122   n
Median of the strain means106   n 121   n
SD of the strain means± 31.5 ± 29.6
Coefficient of variation (CV)0.294 0.243
Min–max range of strain means27.7   –   184   n 70.0   –   194   n
Mean sample size per strain7.8   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 20266.0466 20266.0466 17.8894 < 0.0001
strain 27 324313.9017 12011.626 10.603 < 0.0001
sex:strain 27 51648.4162 1912.9043 1.6886 0.0187
Residuals 371 420289.2655 1132.8552


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 70.9 21.9   8 7.73 0.308 48.0, 109.0 -1.15
B6.PWD-Chr1 m 70.0 23.8   8 8.41 0.34 34.0, 98.0 -1.74
B6.PWD-Chr10.1 f 109.0 23.9   8 8.43 0.219 69.0, 152.0 0.06
B6.PWD-Chr10.1 m 136.0 35.4   8 12.5 0.261 88.0, 184.0 0.49
B6.PWD-Chr10.2 f 144.0 35.9   8 12.7 0.249 82.0, 200.0 1.17
B6.PWD-Chr10.2 m 161.0 27.0   8 9.55 0.168 129.0, 207.0 1.34
B6.PWD-Chr10.3 f 88.1 24.5   8 8.67 0.278 54.0, 123.0 -0.6
B6.PWD-Chr10.3 m 101.0 19.5   8 6.89 0.192 68.0, 125.0 -0.69
B6.PWD-Chr11.1 f 104.0 35.7   8 12.6 0.341 65.0, 169.0 -0.1
B6.PWD-Chr11.1 m 120.0 45.7   8 16.2 0.382 65.0, 196.0 -0.05
B6.PWD-Chr11.2 f 81.3 26.9   7 10.2 0.331 59.0, 130.0 -0.82
B6.PWD-Chr11.2 m 87.0 22.8   7 8.6 0.262 64.0, 132.0 -1.17
B6.PWD-Chr11.3 f 86.0 23.7   8 8.37 0.275 59.0, 133.0 -0.67
B6.PWD-Chr11.3 m 102.0 31.1   8 11.0 0.306 63.0, 149.0 -0.66
B6.PWD-Chr12 f 89.9 30.1   8 10.6 0.335 45.0, 150.0 -0.55
B6.PWD-Chr12 m 101.0 17.4   8 6.14 0.172 72.0, 123.0 -0.69
B6.PWD-Chr13 f 166.0 37.0   8 13.1 0.223 111.0, 218.0 1.87
B6.PWD-Chr13 m 194.0 42.0   8 14.9 0.217 119.0, 260.0 2.45
B6.PWD-Chr14 f 111.0 48.0   8 17.0 0.431 55.0, 206.0 0.13
B6.PWD-Chr14 m 135.0 34.0   8 12.0 0.253 104.0, 201.0 0.46
B6.PWD-Chr15 f 120.0 40.4   8 14.3 0.338 68.0, 194.0 0.41
B6.PWD-Chr15 m 104.0 30.1   8 10.7 0.29 50.0, 135.0 -0.59
B6.PWD-Chr16 f 99.2 26.1   8 9.24 0.263 62.0, 150.0 -0.25
B6.PWD-Chr16 m 105.0 30.4   8 10.8 0.289 63.0, 150.0 -0.56
B6.PWD-Chr17 f 99.4 13.3   8 4.71 0.134 82.0, 121.0 -0.24
B6.PWD-Chr17 m 82.5 20.7   6 8.45 0.251 58.0, 108.0 -1.32
B6.PWD-Chr18 f 127.0 34.2   8 12.1 0.268 88.0, 183.0 0.63
B6.PWD-Chr18 m 123.0 24.5   8 8.66 0.199 93.0, 168.0 0.05
B6.PWD-Chr19 f 89.9 33.3   8 11.8 0.371 40.0, 129.0 -0.55
B6.PWD-Chr19 m 140.0 41.7   7 15.8 0.297 87.0, 194.0 0.62
B6.PWD-Chr2 f 184.0 22.8   8 8.07 0.124 154.0, 216.0 2.45
B6.PWD-Chr2 m 155.0 53.6   8 18.9 0.345 39.0, 214.0 1.13
B6.PWD-Chr3 f 135.0 49.7   8 17.6 0.368 51.0, 201.0 0.89
B6.PWD-Chr3 m 164.0 32.7   3 18.9 0.2 127.0, 190.0 1.44
B6.PWD-Chr5 f 74.2 16.0   8 5.67 0.216 50.0, 96.0 -1.04
B6.PWD-Chr5 m 113.0 34.9   8 12.3 0.309 58.0, 171.0 -0.29
B6.PWD-Chr6 f 86.4 60.5   8 21.4 0.7 11.0, 208.0 -0.66
B6.PWD-Chr6 m 122.0 42.1   8 14.9 0.345 62.0, 188.0 0.02
B6.PWD-Chr8 f 88.6 41.5   5 18.6 0.469 23.0, 130.0 -0.59
B6.PWD-Chr8 m 94.7 25.2   6 10.3 0.266 66.0, 127.0 -0.91
B6.PWD-Chr9 f 121.0 35.4   8 12.5 0.293 72.0, 159.0 0.44
B6.PWD-Chr9 m 162.0 38.4   8 13.6 0.237 109.0, 212.0 1.37
B6.PWD-ChrX.1 f 127.0 19.7   6 8.06 0.156 110.0, 166.0 0.63
B6.PWD-ChrX.1 m 106.0 34.1   8 12.1 0.32 64.0, 158.0 -0.53
B6.PWD-ChrX.2 f 112.0 24.0   8 8.5 0.215 85.0, 156.0 0.16
B6.PWD-ChrX.2 m 97.3 15.7   7 5.93 0.161 80.0, 128.0 -0.82
B6.PWD-ChrX.3 f 75.0 21.0   8 7.43 0.28 43.0, 106.0 -1.02
B6.PWD-ChrX.3 m 123.0 48.2   8 17.0 0.393 61.0, 201.0 0.05
B6.PWD-ChrY f 126.0 31.3   7 11.8 0.249 85.0, 183.0 0.6
B6.PWD-ChrY m 131.0 30.4   7 11.5 0.232 96.0, 162.0 0.32
B6.PWD-mt f 120.0 20.1   8 7.12 0.168 97.0, 161.0 0.41
B6.PWD-mt m 127.0 35.6   8 12.6 0.281 89.0, 189.0 0.18
C57BL/6J f 135.0 35.9   8 12.7 0.266 89.0, 207.0 0.89
C57BL/6J m 159.0 36.2   8 12.8 0.228 108.0, 219.0 1.27
PWD/PhJ f 27.7 34.0   7 12.9 1.23 1.0, 91.0 -2.52
PWD/PhJ m 87.5 47.8   8 16.9 0.546 6.0, 169.0 -1.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 70.875 11.8999 94.2747 47.4753
B6.PWD-Chr1 m 70.0 11.8999 93.3997 46.6003
B6.PWD-Chr10.1 f 109.0 11.8999 132.3997 85.6003
B6.PWD-Chr10.1 m 135.75 11.8999 159.1497 112.3503
B6.PWD-Chr10.2 f 144.125 11.8999 167.5247 120.7253
B6.PWD-Chr10.2 m 161.25 11.8999 184.6497 137.8503
B6.PWD-Chr10.3 f 88.125 11.8999 111.5247 64.7253
B6.PWD-Chr10.3 m 101.375 11.8999 124.7747 77.9753
B6.PWD-Chr11.1 f 104.5 11.8999 127.8997 81.1003
B6.PWD-Chr11.1 m 119.875 11.8999 143.2747 96.4753
B6.PWD-Chr11.2 f 81.2857 12.7215 106.301 56.2704
B6.PWD-Chr11.2 m 87.0 12.7215 112.0153 61.9847
B6.PWD-Chr11.3 f 86.0 11.8999 109.3997 62.6003
B6.PWD-Chr11.3 m 101.625 11.8999 125.0247 78.2253
B6.PWD-Chr12 f 89.875 11.8999 113.2747 66.4753
B6.PWD-Chr12 m 100.875 11.8999 124.2747 77.4753
B6.PWD-Chr13 f 165.625 11.8999 189.0247 142.2253
B6.PWD-Chr13 m 193.5 11.8999 216.8997 170.1003
B6.PWD-Chr14 f 111.375 11.8999 134.7747 87.9753
B6.PWD-Chr14 m 134.75 11.8999 158.1497 111.3503
B6.PWD-Chr15 f 119.625 11.8999 143.0247 96.2253
B6.PWD-Chr15 m 103.75 11.8999 127.1497 80.3503
B6.PWD-Chr16 f 99.25 11.8999 122.6497 75.8503
B6.PWD-Chr16 m 105.25 11.8999 128.6497 81.8503
B6.PWD-Chr17 f 99.375 11.8999 122.7747 75.9753
B6.PWD-Chr17 m 82.5 13.7408 109.5196 55.4804
B6.PWD-Chr18 f 127.375 11.8999 150.7747 103.9753
B6.PWD-Chr18 m 123.375 11.8999 146.7747 99.9753
B6.PWD-Chr19 f 89.875 11.8999 113.2747 66.4753
B6.PWD-Chr19 m 140.2857 12.7215 165.301 115.2704
B6.PWD-Chr2 f 183.875 11.8999 207.2747 160.4753
B6.PWD-Chr2 m 155.375 11.8999 178.7747 131.9753
B6.PWD-Chr3 f 135.25 11.8999 158.6497 111.8503
B6.PWD-Chr3 m 163.6667 19.4324 201.8781 125.4552
B6.PWD-Chr5 f 74.25 11.8999 97.6497 50.8503
B6.PWD-Chr5 m 113.125 11.8999 136.5247 89.7253
B6.PWD-Chr6 f 86.375 11.8999 109.7747 62.9753
B6.PWD-Chr6 m 121.875 11.8999 145.2747 98.4753
B6.PWD-Chr8 f 88.6 15.0523 118.1985 59.0015
B6.PWD-Chr8 m 94.6667 13.7408 121.6863 67.6471
B6.PWD-Chr9 f 120.625 11.8999 144.0247 97.2253
B6.PWD-Chr9 m 161.625 11.8999 185.0247 138.2253
B6.PWD-ChrX.1 f 126.8333 13.7408 153.8529 99.8137
B6.PWD-ChrX.1 m 106.5 11.8999 129.8997 83.1003
B6.PWD-ChrX.2 f 111.875 11.8999 135.2747 88.4753
B6.PWD-ChrX.2 m 97.2857 12.7215 122.301 72.2704
B6.PWD-ChrX.3 f 75.0 11.8999 98.3997 51.6003
B6.PWD-ChrX.3 m 122.625 11.8999 146.0247 99.2253
B6.PWD-ChrY f 125.5714 12.7215 150.5867 100.5561
B6.PWD-ChrY m 131.2857 12.7215 156.301 106.2704
B6.PWD-mt f 119.5 11.8999 142.8997 96.1003
B6.PWD-mt m 126.625 11.8999 150.0247 103.2253
C57BL/6J f 134.75 11.8999 158.1497 111.3503
C57BL/6J m 158.75 11.8999 182.1497 135.3503
PWD/PhJ f 27.7143 12.7215 52.7296 2.699
PWD/PhJ m 87.5 11.8999 110.8997 64.1003


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 70.4375 8.4145 86.9836 53.8914
B6.PWD-Chr10.1 both 122.375 8.4145 138.9211 105.8289
B6.PWD-Chr10.2 both 152.6875 8.4145 169.2336 136.1414
B6.PWD-Chr10.3 both 94.75 8.4145 111.2961 78.2039
B6.PWD-Chr11.1 both 112.1875 8.4145 128.7336 95.6414
B6.PWD-Chr11.2 both 84.1429 8.9955 101.8313 66.4544
B6.PWD-Chr11.3 both 93.8125 8.4145 110.3586 77.2664
B6.PWD-Chr12 both 95.375 8.4145 111.9211 78.8289
B6.PWD-Chr13 both 179.5625 8.4145 196.1086 163.0164
B6.PWD-Chr14 both 123.0625 8.4145 139.6086 106.5164
B6.PWD-Chr15 both 111.6875 8.4145 128.2336 95.1414
B6.PWD-Chr16 both 102.25 8.4145 118.7961 85.7039
B6.PWD-Chr17 both 90.9375 9.0887 108.8093 73.0657
B6.PWD-Chr18 both 125.375 8.4145 141.9211 108.8289
B6.PWD-Chr19 both 115.0804 8.7098 132.2071 97.9536
B6.PWD-Chr2 both 169.625 8.4145 186.1711 153.0789
B6.PWD-Chr3 both 149.4583 11.3933 171.8618 127.0549
B6.PWD-Chr5 both 93.6875 8.4145 110.2336 77.1414
B6.PWD-Chr6 both 104.125 8.4145 120.6711 87.5789
B6.PWD-Chr8 both 91.6333 10.1904 111.6716 71.5951
B6.PWD-Chr9 both 141.125 8.4145 157.6711 124.5789
B6.PWD-ChrX.1 both 116.6667 9.0887 134.5384 98.7949
B6.PWD-ChrX.2 both 104.5804 8.7098 121.7071 87.4536
B6.PWD-ChrX.3 both 98.8125 8.4145 115.3586 82.2664
B6.PWD-ChrY both 128.4286 8.9955 146.117 110.7401
B6.PWD-mt both 123.0625 8.4145 139.6086 106.5164
C57BL/6J both 146.75 8.4145 163.2961 130.2039
PWD/PhJ both 57.6071 8.7098 74.7339 40.4804




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA