Project measure / variable:   Donahue3   duration_perimeter

ID, description, units MPD:37715   duration_perimeter   duration of activity along perimeter of arena, thigmotaxis, 10 min test   [s]  
Data set, strains Donahue3   B6.A consomic w/par   22 strains     sex: both     age: 6-7wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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Donahue3 - duration of activity along perimeter of arena, thigmotaxis, 10 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains22 strains
Mean of the strain means509   s 496   s
Median of the strain means514   s 498   s
SD of the strain means± 24.8 ± 22.2
Coefficient of variation (CV)0.0487 0.0448
Min–max range of strain means416   –   530   s 435   –   534   s
Mean sample size per strain8.0   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 15399.191 15399.191 5.9208 0.0155
strain 21 165251.8244 7869.1345 3.0256 < 0.0001
sex:strain 21 19573.799 932.0857 0.3584 0.9964
Residuals 308 801069.04 2600.8735


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 416.0 261.0   8 92.2 0.627 -3.76
A/J m 435.0 125.0   8 44.1 0.287 246.0, 581.0 -2.75
B6.A-Chr1 f 523.0 20.1   8 7.12 0.0385 492.0, 557.0 0.55
B6.A-Chr1 m 524.0 20.4   8 7.22 0.039 484.0, 550.0 1.26
B6.A-Chr10 f 485.0 39.8   8 14.1 0.082 413.0, 534.0 -0.98
B6.A-Chr10 m 484.0 36.6   8 12.9 0.0756 410.0, 521.0 -0.54
B6.A-Chr11 f 530.0 18.6   8 6.57 0.0351 507.0, 562.0 0.83
B6.A-Chr11 m 509.0 24.9   8 8.81 0.0489 471.0, 537.0 0.58
B6.A-Chr12 f 530.0 26.3   8 9.28 0.0496 468.0, 551.0 0.83
B6.A-Chr12 m 498.0 27.7   8 9.79 0.0556 450.0, 526.0 0.09
B6.A-Chr13 f 530.0 16.8   8 5.92 0.0316 499.0, 553.0 0.83
B6.A-Chr13 m 502.0 31.8   8 11.2 0.0633 432.0, 534.0 0.27
B6.A-Chr14 f 514.0 24.1   8 8.52 0.0469 469.0, 545.0 0.19
B6.A-Chr14 m 498.0 19.2   8 6.8 0.0387 460.0, 515.0 0.09
B6.A-Chr15 f 498.0 38.6   8 13.6 0.0775 440.0, 540.0 -0.46
B6.A-Chr15 m 498.0 9.68   8 3.42 0.0194 483.0, 510.0 0.09
B6.A-Chr16 f 528.0 29.9   8 10.6 0.0567 491.0, 564.0 0.75
B6.A-Chr16 m 513.0 30.0   8 10.6 0.0586 460.0, 554.0 0.76
B6.A-Chr17 f 509.0 22.4   8 7.93 0.0441 471.0, 540.0 -0.01
B6.A-Chr17 m 485.0 27.6   8 9.77 0.057 456.0, 538.0 -0.5
B6.A-Chr18 f 527.0 21.1   8 7.47 0.0401 493.0, 558.0 0.71
B6.A-Chr18 m 518.0 24.2   8 8.55 0.0467 475.0, 553.0 0.99
B6.A-Chr19 f 515.0 27.0   8 9.55 0.0524 475.0, 555.0 0.23
B6.A-Chr19 m 521.0 29.0   8 10.3 0.0558 456.0, 554.0 1.12
B6.A-Chr2 f 523.0 13.0   8 4.6 0.0249 504.0, 542.0 0.55
B6.A-Chr2 m 509.0 18.0   8 6.38 0.0354 471.0, 529.0 0.58
B6.A-Chr3 f 511.0 28.8   8 10.2 0.0563 465.0, 561.0 0.07
B6.A-Chr3 m 490.0 23.2   8 8.21 0.0474 461.0, 525.0 -0.27
B6.A-Chr4 f 517.0 36.5   8 12.9 0.0707 463.0, 561.0 0.31
B6.A-Chr4 m 534.0 21.1   8 7.47 0.0396 500.0, 556.0 1.71
B6.A-Chr5 f 517.0 28.1   8 9.95 0.0544 461.0, 549.0 0.31
B6.A-Chr5 m 496.0 33.7   8 11.9 0.0679 452.0, 543.0 0.0
B6.A-Chr6 f 511.0 35.5   8 12.6 0.0695 461.0, 562.0 0.07
B6.A-Chr6 m 478.0 50.2   8 17.8 0.105 408.0, 541.0 -0.81
B6.A-Chr7 f 510.0 21.5   8 7.6 0.0421 479.0, 545.0 0.03
B6.A-Chr7 m 507.0 20.7   8 7.31 0.0408 479.0, 540.0 0.49
B6.A-Chr8 f 488.0 30.6   8 10.8 0.0628 443.0, 528.0 -0.86
B6.A-Chr8 m 471.0 29.8   8 10.5 0.0632 406.0, 501.0 -1.13
B6.A-Chr9 f 494.0 22.7   8 8.02 0.0459 445.0, 519.0 -0.62
B6.A-Chr9 m 476.0 25.8   8 9.13 0.0542 436.0, 518.0 -0.9
B6.A-ChrX f 526.0 18.2   8 6.44 0.0346 501.0, 556.0 0.67
B6.A-ChrX m 500.0 14.2   8 5.0 0.0283 482.0, 519.0 0.18
C57BL/6J f 503.0 29.7   8 10.5 0.0591 459.0, 546.0 -0.25
C57BL/6J m 467.0 22.3   8 7.88 0.0477 443.0, 512.0 -1.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 416.2875 18.0308 451.7666 380.8084
A/J m 435.475 18.0308 470.9541 399.9959
B6.A-Chr1 f 522.925 18.0308 558.4041 487.4459
B6.A-Chr1 m 523.75 18.0308 559.2291 488.2709
B6.A-Chr10 f 485.425 18.0308 520.9041 449.9459
B6.A-Chr10 m 484.0625 18.0308 519.5416 448.5834
B6.A-Chr11 f 530.4625 18.0308 565.9416 494.9834
B6.A-Chr11 m 509.3375 18.0308 544.8166 473.8584
B6.A-Chr12 f 529.5125 18.0308 564.9916 494.0334
B6.A-Chr12 m 498.0375 18.0308 533.5166 462.5584
B6.A-Chr13 f 530.4875 18.0308 565.9666 495.0084
B6.A-Chr13 m 502.0125 18.0308 537.4916 466.5334
B6.A-Chr14 f 514.075 18.0308 549.5541 478.5959
B6.A-Chr14 m 497.725 18.0308 533.2041 462.2459
B6.A-Chr15 f 497.5875 18.0308 533.0666 462.1084
B6.A-Chr15 m 498.4875 18.0308 533.9666 463.0084
B6.A-Chr16 f 527.525 18.0308 563.0041 492.0459
B6.A-Chr16 m 512.5625 18.0308 548.0416 477.0834
B6.A-Chr17 f 508.5875 18.0308 544.0666 473.1084
B6.A-Chr17 m 485.4 18.0308 520.8791 449.9209
B6.A-Chr18 f 527.3875 18.0308 562.8666 491.9084
B6.A-Chr18 m 517.5625 18.0308 553.0416 482.0834
B6.A-Chr19 f 515.2 18.0308 550.6791 479.7209
B6.A-Chr19 m 520.725 18.0308 556.2041 485.2459
B6.A-Chr2 f 522.6625 18.0308 558.1416 487.1834
B6.A-Chr2 m 508.9875 18.0308 544.4666 473.5084
B6.A-Chr3 f 511.1 18.0308 546.5791 475.6209
B6.A-Chr3 m 490.1625 18.0308 525.6416 454.6834
B6.A-Chr4 f 517.0125 18.0308 552.4916 481.5334
B6.A-Chr4 m 533.5125 18.0308 568.9916 498.0334
B6.A-Chr5 f 516.75 18.0308 552.2291 481.2709
B6.A-Chr5 m 495.9375 18.0308 531.4166 460.4584
B6.A-Chr6 f 511.3625 18.0308 546.8416 475.8834
B6.A-Chr6 m 478.0125 18.0308 513.4916 442.5334
B6.A-Chr7 f 510.1875 18.0308 545.6666 474.7084
B6.A-Chr7 m 507.425 18.0308 542.9041 471.9459
B6.A-Chr8 f 487.5125 18.0308 522.9916 452.0334
B6.A-Chr8 m 471.1625 18.0308 506.6416 435.6834
B6.A-Chr9 f 494.0625 18.0308 529.5416 458.5834
B6.A-Chr9 m 476.125 18.0308 511.6041 440.6459
B6.A-ChrX f 526.2 18.0308 561.6791 490.7209
B6.A-ChrX m 500.25 18.0308 535.7291 464.7709
C57BL/6J f 502.5125 18.0308 537.9916 467.0334
C57BL/6J m 467.0875 18.0308 502.5666 431.6084


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 425.8813 12.7497 450.9688 400.7937
B6.A-Chr1 both 523.3375 12.7497 548.425 498.25
B6.A-Chr10 both 484.7438 12.7497 509.8313 459.6562
B6.A-Chr11 both 519.9 12.7497 544.9875 494.8125
B6.A-Chr12 both 513.775 12.7497 538.8625 488.6875
B6.A-Chr13 both 516.25 12.7497 541.3375 491.1625
B6.A-Chr14 both 505.9 12.7497 530.9875 480.8125
B6.A-Chr15 both 498.0375 12.7497 523.125 472.95
B6.A-Chr16 both 520.0437 12.7497 545.1313 494.9562
B6.A-Chr17 both 496.9937 12.7497 522.0813 471.9062
B6.A-Chr18 both 522.475 12.7497 547.5625 497.3875
B6.A-Chr19 both 517.9625 12.7497 543.05 492.875
B6.A-Chr2 both 515.825 12.7497 540.9125 490.7375
B6.A-Chr3 both 500.6313 12.7497 525.7188 475.5437
B6.A-Chr4 both 525.2625 12.7497 550.35 500.175
B6.A-Chr5 both 506.3438 12.7497 531.4313 481.2562
B6.A-Chr6 both 494.6875 12.7497 519.775 469.6
B6.A-Chr7 both 508.8062 12.7497 533.8938 483.7187
B6.A-Chr8 both 479.3375 12.7497 504.425 454.25
B6.A-Chr9 both 485.0937 12.7497 510.1813 460.0062
B6.A-ChrX both 513.225 12.7497 538.3125 488.1375
C57BL/6J both 484.8 12.7497 509.8875 459.7125




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA