Phenotype measure:   Vulpe1   zinc

ID, description, units MPD:36803   zinc   zinc (Zn) content in liver, dry weight   [µg/g]
Data set, strains Vulpe1   inbred   18 strains     sex: both     age: 8wks
Procedure mineral quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Vulpe1 - zinc (Zn) content in liver, dry weight



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains17 strains
Mean of the strain means73.8   µg/g 78.7   µg/g
Median of the strain means73.1   µg/g 82.0   µg/g
SD of the strain means± 9.80 ± 11.2
Coefficient of variation (CV)0.133 0.143
Min–max range of strain means53.8   –   94.5   µg/g 52.1   –   92.6   µg/g
Mean sample size per strain6.5   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2198.5253 2198.5253 33.5862 < 0.0001
strain 16 16331.6525 1020.7283 15.5933 < 0.0001
sex:strain 16 4458.1637 278.6352 4.2566 < 0.0001
Residuals 191 12502.716 65.4592


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 65.5 7.28   6 2.97 0.111 54.2, 74.1 -0.84
129S1/SvImJ m 79.6 5.89   6 2.4 0.0739 71.8, 87.7 0.08
A/HeJ f 78.3 5.86   6 2.39 0.0749 67.3, 84.1 0.46
A/HeJ m 85.2 3.81   6 1.56 0.0447 81.5, 91.8 0.57
A/J f 75.7 10.3   6 4.2 0.136 64.5, 88.2 0.2
A/J m 92.6 16.7   6 6.82 0.18 75.4, 120.0 1.23
AKR/J f 71.8 5.72   6 2.33 0.0796 65.2, 78.3 -0.2
AKR/J m 64.5 5.19   6 2.12 0.0804 59.4, 73.5 -1.27
B10.D2-Hc0 f 56.8 3.35   6 1.37 0.0589 52.2, 61.0 -1.73
B10.D2-Hc0 m 52.1 3.71   6 1.51 0.0711 47.0, 58.2 -2.37
BALB/cByJ f 73.6 11.4   6 4.64 0.154 52.1, 84.7 -0.02
BALB/cByJ m 70.0 3.38   6 1.38 0.0482 64.0, 73.6 -0.78
BALB/cJ f 70.1 4.36   6 1.78 0.0621 66.4, 78.1 -0.37
BALB/cJ m 85.2 10.3   6 4.2 0.121 67.6, 97.4 0.57
C3H/HeJ f 84.3 7.21   5 3.23 0.0855 72.7, 91.7 1.08
C3H/HeJ m 78.7 9.58   6 3.91 0.122 64.6, 90.0 0.0
C57BL/6J f 73.4 8.16   10 2.58 0.111 60.5, 83.5 -0.04
C57BL/6J m 82.0 11.0   6 4.48 0.134 66.0, 95.5 0.29
CAST/EiJ f 72.2 10.0   11 3.02 0.139 58.0, 89.9 -0.16
CAST/EiJ m 85.6 9.15   7 3.46 0.107 71.0, 97.7 0.61
DBA/2J f 67.5 5.87   12 1.69 0.0869 53.1, 74.0 -0.64
DBA/2J m 71.0 5.48   12 1.58 0.0772 63.0, 79.0 -0.69
LG/J f 83.3 8.79   6 3.59 0.106 69.7, 94.3 0.97
LG/J m 87.1 16.9   6 6.9 0.194 70.5, 117.0 0.74
LP/J f 72.6 8.24   6 3.37 0.114 58.4, 81.8 -0.12
LP/J m 80.1 7.3   6 2.98 0.0911 69.9, 89.1 0.12
MRL/MpJ f 72.8 2.78   6 1.14 0.0382 69.9, 76.3 -0.1
MRL/MpJ m 88.2 5.17   6 2.11 0.0586 83.3, 95.5 0.84
NZB/BlNJ f 94.5 6.31   6 2.58 0.0668 83.6, 102.0 2.12
NZB/BlNJ m 82.2 5.79   10 1.83 0.0705 70.0, 88.9 0.31
NZW/LacJ f 86.3 3.32   6 1.36 0.0385 83.1, 91.2 1.28
SM/J f 75.2 13.9   4 6.94 0.185 61.6, 93.5 0.15
SM/J m 92.4 4.69   6 1.91 0.0508 85.3, 97.2 1.22
SPRET/EiJ f 53.8 7.06   6 2.88 0.131 44.6, 66.2 -2.04
SPRET/EiJ m 62.1 3.35   4 1.68 0.054 57.8, 65.2 -1.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 65.5 3.303 72.0151 58.9849
129S1/SvImJ m 79.6167 3.303 86.1317 73.1016
A/HeJ f 78.25 3.303 84.7651 71.7349
A/HeJ m 85.2167 3.303 91.7317 78.7016
A/J f 75.6667 3.303 82.1817 69.1516
A/J m 92.5667 3.303 99.0817 86.0516
AKR/J f 71.8 3.303 78.3151 65.2849
AKR/J m 64.5333 3.303 71.0484 58.0183
B10.D2-Hc0 f 56.7833 3.303 63.2984 50.2683
B10.D2-Hc0 m 52.15 3.303 58.6651 45.6349
BALB/cByJ f 73.6167 3.303 80.1317 67.1016
BALB/cByJ m 70.0333 3.303 76.5484 63.5183
BALB/cJ f 70.15 3.303 76.6651 63.6349
BALB/cJ m 85.25 3.303 91.7651 78.7349
C3H/HeJ f 84.34 3.6183 91.4769 77.2031
C3H/HeJ m 78.7 3.303 85.2151 72.1849
C57BL/6J f 73.4 2.5585 78.4465 68.3535
C57BL/6J m 82.0 3.303 88.5151 75.4849
CAST/EiJ f 72.1545 2.4394 76.9662 67.3429
CAST/EiJ m 85.6143 3.058 91.6461 79.5825
DBA/2J f 67.525 2.3356 72.1318 62.9182
DBA/2J m 71.0417 2.3356 75.6485 66.4348
LG/J f 83.3167 3.303 89.8317 76.8016
LG/J m 87.1333 3.303 93.6484 80.6183
LP/J f 72.5667 3.303 79.0817 66.0516
LP/J m 80.1167 3.303 86.6317 73.6016
MRL/MpJ f 72.8333 3.303 79.3484 66.3183
MRL/MpJ m 88.2 3.303 94.7151 81.6849
NZB/BlNJ f 94.4667 3.303 100.9817 87.9516
NZB/BlNJ m 82.16 2.5585 87.2065 77.1135
SM/J f 75.2 4.0453 83.1793 67.2207
SM/J m 92.3833 3.303 98.8984 85.8683
SPRET/EiJ f 53.8 3.303 60.3151 47.2849
SPRET/EiJ m 62.125 4.0453 70.1043 54.1457


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 72.5583 2.3356 77.1652 67.9515
A/HeJ both 81.7333 2.3356 86.3402 77.1265
A/J both 84.1167 2.3356 88.7235 79.5098
AKR/J both 68.1667 2.3356 72.7735 63.5598
B10.D2-Hc0 both 54.4667 2.3356 59.0735 49.8598
BALB/cByJ both 71.825 2.3356 76.4318 67.2182
BALB/cJ both 77.7 2.3356 82.3068 73.0932
C3H/HeJ both 81.52 2.4496 86.3517 76.6883
C57BL/6J both 77.7 2.089 81.8205 73.5795
CAST/EiJ both 78.8844 1.9559 82.7424 75.0265
DBA/2J both 69.2833 1.6515 72.5409 66.0258
LG/J both 85.225 2.3356 89.8318 80.6182
LP/J both 76.3417 2.3356 80.9485 71.7348
MRL/MpJ both 80.5167 2.3356 85.1235 75.9098
NZB/BlNJ both 88.3133 2.089 92.4338 84.1928
SM/J both 83.7917 2.6113 88.9423 78.6411
SPRET/EiJ both 57.9625 2.6113 63.1131 52.8119




  GWAS USING LINEAR MIXED MODELS