Phenotype measure:   Vulpe1   iron

ID, description, units MPD:36802   iron   iron (Fe) content in liver, dry weight   [µg/g]
Data set, strains Vulpe1   inbred   18 strains     sex: both     age: 8wks
Procedure mineral quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Vulpe1 - iron (Fe) content in liver, dry weight



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains17 strains
Mean of the strain means392   µg/g 364   µg/g
Median of the strain means396   µg/g 360   µg/g
SD of the strain means± 117 ± 138
Coefficient of variation (CV)0.298 0.378
Min–max range of strain means222   –   659   µg/g 153   –   661   µg/g
Mean sample size per strain6.5   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 79020.5142 79020.5142 10.9234 0.0011
strain 16 3139266.709 196204.1693 27.1222 < 0.0001
sex:strain 16 372382.3061 23273.8941 3.2173 0.0001
Residuals 191 1381709.3329 7234.0803


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 376.0 62.6   6 25.5 0.167 306.0, 469.0 -0.14
129S1/SvImJ m 547.0 85.9   6 35.1 0.157 441.0, 690.0 1.32
A/HeJ f 395.0 40.3   6 16.4 0.102 332.0, 456.0 0.02
A/HeJ m 360.0 44.5   6 18.2 0.124 303.0, 435.0 -0.03
A/J f 400.0 108.0   6 44.1 0.27 283.0, 568.0 0.07
A/J m 321.0 51.4   6 21.0 0.16 255.0, 383.0 -0.32
AKR/J f 659.0 195.0   6 79.5 0.296 442.0, 917.0 2.28
AKR/J m 661.0 142.0   6 57.8 0.214 486.0, 877.0 2.15
B10.D2-Hc0 f 250.0 33.6   6 13.7 0.135 217.0, 304.0 -1.22
B10.D2-Hc0 m 153.0 27.3   6 11.2 0.178 107.0, 189.0 -1.54
BALB/cByJ f 439.0 86.6   6 35.4 0.197 335.0, 574.0 0.4
BALB/cByJ m 317.0 26.0   6 10.6 0.082 282.0, 358.0 -0.34
BALB/cJ f 561.0 25.9   6 10.6 0.0461 529.0, 591.0 1.44
BALB/cJ m 396.0 105.0   6 42.9 0.265 269.0, 527.0 0.23
C3H/HeJ f 396.0 13.9   5 6.22 0.0351 385.0, 420.0 0.03
C3H/HeJ m 222.0 15.7   6 6.4 0.0708 199.0, 244.0 -1.03
C57BL/6J f 273.0 63.1   10 19.9 0.231 182.0, 389.0 -1.02
C57BL/6J m 298.0 60.2   6 24.6 0.202 202.0, 377.0 -0.48
CAST/EiJ f 420.0 113.0   11 34.1 0.269 296.0, 700.0 0.24
CAST/EiJ m 450.0 154.0   7 58.4 0.343 288.0, 715.0 0.62
DBA/2J f 270.0 54.0   12 15.6 0.2 203.0, 366.0 -1.05
DBA/2J m 203.0 27.3   12 7.89 0.135 159.0, 248.0 -1.17
LG/J f 510.0 144.0   6 58.7 0.282 383.0, 791.0 1.01
LG/J m 462.0 163.0   6 66.7 0.354 272.0, 701.0 0.71
LP/J f 467.0 71.5   6 29.2 0.153 380.0, 594.0 0.64
LP/J m 532.0 117.0   6 47.8 0.22 387.0, 710.0 1.22
MRL/MpJ f 367.0 44.3   6 18.1 0.121 298.0, 437.0 -0.22
MRL/MpJ m 408.0 102.0   6 41.5 0.249 287.0, 568.0 0.32
NZB/BlNJ f 243.0 17.6   6 7.2 0.0726 208.0, 258.0 -1.28
NZB/BlNJ m 227.0 59.9   10 18.9 0.264 150.0, 299.0 -1.0
NZW/LacJ f 342.0 30.9   6 12.6 0.0904 301.0, 385.0 -0.43
SM/J f 222.0 55.3   4 27.6 0.249 156.0, 288.0 -1.46
SM/J m 242.0 15.4   6 6.3 0.0637 219.0, 258.0 -0.89
SPRET/EiJ f 472.0 69.6   6 28.4 0.148 378.0, 549.0 0.68
SPRET/EiJ m 397.0 55.1   4 27.5 0.139 342.0, 473.0 0.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 375.5 34.7229 443.9896 307.0104
129S1/SvImJ m 547.1667 34.7229 615.6563 478.6771
A/HeJ f 394.6667 34.7229 463.1563 326.1771
A/HeJ m 360.3333 34.7229 428.8229 291.8437
A/J f 400.5 34.7229 468.9896 332.0104
A/J m 320.6667 34.7229 389.1563 252.1771
AKR/J f 658.6667 34.7229 727.1563 590.1771
AKR/J m 661.1667 34.7229 729.6563 592.6771
B10.D2-Hc0 f 249.6667 34.7229 318.1563 181.1771
B10.D2-Hc0 m 153.1667 34.7229 221.6563 84.6771
BALB/cByJ f 438.8333 34.7229 507.3229 370.3437
BALB/cByJ m 316.8333 34.7229 385.3229 248.3437
BALB/cJ f 561.3333 34.7229 629.8229 492.8437
BALB/cJ m 396.3333 34.7229 464.8229 327.8437
C3H/HeJ f 395.8 38.037 470.8266 320.7734
C3H/HeJ m 221.5 34.7229 289.9896 153.0104
C57BL/6J f 273.0 26.8962 326.0518 219.9482
C57BL/6J m 297.6667 34.7229 366.1563 229.1771
CAST/EiJ f 419.9091 25.6446 470.492 369.3262
CAST/EiJ m 450.1429 32.1472 513.5519 386.7338
DBA/2J f 269.8333 24.5528 318.2628 221.4039
DBA/2J m 202.75 24.5528 251.1795 154.3205
LG/J f 509.5 34.7229 577.9896 441.0104
LG/J m 461.6667 34.7229 530.1563 393.1771
LP/J f 467.0 34.7229 535.4896 398.5104
LP/J m 532.0 34.7229 600.4896 463.5104
MRL/MpJ f 367.3333 34.7229 435.8229 298.8437
MRL/MpJ m 407.8333 34.7229 476.3229 339.3437
NZB/BlNJ f 242.8333 34.7229 311.3229 174.3437
NZB/BlNJ m 227.3 26.8962 280.3518 174.2482
SM/J f 222.0 42.5267 305.8823 138.1177
SM/J m 242.0 34.7229 310.4896 173.5104
SPRET/EiJ f 471.8333 34.7229 540.3229 403.3437
SPRET/EiJ m 396.75 42.5267 480.6323 312.8677


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 461.3333 24.5528 509.7628 412.9039
A/HeJ both 377.5 24.5528 425.9295 329.0705
A/J both 360.5833 24.5528 409.0128 312.1539
AKR/J both 659.9167 24.5528 708.3461 611.4872
B10.D2-Hc0 both 201.4167 24.5528 249.8461 152.9872
BALB/cByJ both 377.8333 24.5528 426.2628 329.4039
BALB/cJ both 478.8333 24.5528 527.2628 430.4039
C3H/HeJ both 308.65 25.7512 359.4433 257.8567
C57BL/6J both 285.3333 21.9607 328.65 242.0167
CAST/EiJ both 435.026 20.5614 475.5825 394.4694
DBA/2J both 236.2917 17.3615 270.5365 202.0469
LG/J both 485.5833 24.5528 534.0128 437.1539
LP/J both 499.5 24.5528 547.9295 451.0705
MRL/MpJ both 387.5833 24.5528 436.0128 339.1539
NZB/BlNJ both 235.0667 21.9607 278.3833 191.75
SM/J both 232.0 27.4509 286.1458 177.8542
SPRET/EiJ both 434.2917 27.4509 488.4375 380.1459




  GWAS USING LINEAR MIXED MODELS