Project measure / variable:   Xing2   gait_score_M18

ID, description, units MPD:36306   gait_score_M18   gait score (1-3)   [score]  at age 18mo  
Data set, strains Xing2   inbred   29 strains     sex: both     age: 78wks
Procedure gait analysis
Ontology mappings

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  STRAIN COMPARISON PLOT
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Xing2 - gait score (1-3) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains27 strains
Mean of the strain means2.49   score 2.39   score
Median of the strain means2.71   score 2.62   score
SD of the strain means± 0.552 ± 0.649
Coefficient of variation (CV)0.221 0.272
Min–max range of strain means1.00   –   3.00   score 1.00   –   3.00   score
Mean sample size per strain6.7   mice 6.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1161 0.1161 0.3075 0.5796
strain 24 99.5164 4.1465 10.9834 < 0.0001
sex:strain 24 16.1913 0.6746 1.787 0.0147
Residuals 290 109.4821 0.3775


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.62 0.744   8 0.263 0.458 1.0, 3.0 -1.58
129S1/SvImJ m 1.29 0.488   7 0.184 0.38 1.0, 2.0 -1.69
A/J f 1.38 0.518   8 0.183 0.376 1.0, 2.0 -2.02
A/J m 1.33 0.516   6 0.211 0.387 1.0, 2.0 -1.63
BALB/cByJ f 2.75 0.463   8 0.164 0.168 2.0, 3.0 0.47
BALB/cByJ m 3.0 0.0   6 0.0 0.0 3.0, 3.0 0.95
BTBR T+ Itpr3tf/J f 2.88 0.354   8 0.125 0.123 2.0, 3.0 0.7
BTBR T+ Itpr3tf/J m 3.0 0.0   3 0.0 0.0 3.0, 3.0 0.95
BUB/BnJ f 1.0 0.0   3 0.0 0.0 1.0, 1.0 -2.7
BUB/BnJ m 1.0 0.0   7 0.0 0.0 1.0, 1.0 -2.14
C3H/HeJ f 2.62 0.744   8 0.263 0.283 1.0, 3.0 0.23
C3H/HeJ m 2.12 0.835   8 0.295 0.393 1.0, 3.0 -0.41
C57BL/10J f 2.83 0.408   6 0.167 0.144 2.0, 3.0 0.61
C57BL/10J m 2.86 0.378   7 0.143 0.132 2.0, 3.0 0.73
C57BL/6J f 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.92
C57BL/6J m 2.62 0.744   8 0.263 0.283 1.0, 3.0 0.36
C57BLKS/J f 1.75 0.886   8 0.313 0.507 1.0, 3.0 -1.35
C57BLKS/J m 1.88 0.835   8 0.295 0.445 1.0, 3.0 -0.78
C57BR/cdJ f 2.12 0.991   8 0.35 0.466 1.0, 3.0 -0.68
C57BR/cdJ m 1.5 0.756   8 0.267 0.504 1.0, 3.0 -1.37
C57L/J f 2.71 0.756   7 0.286 0.279 1.0, 3.0 0.39
C57L/J m 2.57 0.756   14 0.202 0.294 1.0, 3.0 0.28
CAST/EiJ f 2.71 0.756   7 0.286 0.279 1.0, 3.0 0.39
CBA/J f 2.57 0.787   7 0.297 0.306 1.0, 3.0 0.14
CBA/J m 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.95
DBA/2J f 2.67 0.816   6 0.333 0.306 1.0, 3.0 0.32
DBA/2J m 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.95
FVB/NJ f 2.29 0.951   7 0.36 0.416 1.0, 3.0 -0.37
FVB/NJ m 1.5 1.0   4 0.5 0.667 1.0, 3.0 -1.37
KK/HlJ f 1.62 0.916   8 0.324 0.564 1.0, 3.0 -1.58
KK/HlJ m 2.71 0.756   7 0.286 0.279 1.0, 3.0 0.5
LP/J f 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.92
LP/J m 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.95
MRL/MpJ f 2.71 0.756   7 0.286 0.279 1.0, 3.0 0.39
MRL/MpJ m 2.62 0.744   8 0.263 0.283 1.0, 3.0 0.36
NOD.B10Sn-H2b/J f 3.0 0.0   5 0.0 0.0 3.0, 3.0 0.92
NOD.B10Sn-H2b/J m 3.0 0.0   6 0.0 0.0 3.0, 3.0 0.95
NZO/HlLtJ f 2.83 0.408   6 0.167 0.144 2.0, 3.0 0.61
NZO/HlLtJ m 1.5 0.707   2   0.5 0.471 1.0, 2.0 -1.37
NZW/LacJ f 2.62 0.518   8 0.183 0.197 2.0, 3.0 0.23
NZW/LacJ m 2.5 0.548   6 0.224 0.219 2.0, 3.0 0.17
P/J f 2.5 0.837   6 0.342 0.335 1.0, 3.0 0.01
P/J m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.6
PL/J f 3.0 0.0   1   0.0 0.0 3.0, 3.0 0.92
PL/J m 2.5 0.756   8 0.267 0.302 1.0, 3.0 0.17
PWD/PhJ f 2.83 0.408   6 0.167 0.144 2.0, 3.0 0.61
PWD/PhJ m 2.86 0.378   7 0.143 0.132 2.0, 3.0 0.73
RIIIS/J f 1.86 1.07   7 0.404 0.576 1.0, 3.0 -1.15
RIIIS/J m 2.75 0.5   4 0.25 0.182 2.0, 3.0 0.56
SJL/J f 3.0 0.0   4 0.0 0.0 3.0, 3.0 0.92
SM/J f 2.67 0.516   6 0.211 0.194 2.0, 3.0 0.32
SM/J m 2.33 0.707   9 0.236 0.303 1.0, 3.0 -0.09
SWR/J f 2.75 0.5   4 0.25 0.182 2.0, 3.0 0.47
SWR/J m 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.95
WSB/EiJ f 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.92
WSB/EiJ m 3.0 0.0   4 0.0 0.0 3.0, 3.0 0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.625 0.2172 2.0526 1.1974
129S1/SvImJ m 1.2857 0.2322 1.7428 0.8286
A/J f 1.375 0.2172 1.8026 0.9474
A/J m 1.3333 0.2508 1.827 0.8396
BALB/cByJ f 2.75 0.2172 3.1776 2.3224
BALB/cByJ m 3.0 0.2508 3.4937 2.5063
BTBR T+ Itpr3tf/J f 2.875 0.2172 3.3026 2.4474
BTBR T+ Itpr3tf/J m 3.0 0.3547 3.6982 2.3018
BUB/BnJ f 1.0 0.3547 1.6982 0.3018
BUB/BnJ m 1.0 0.2322 1.4571 0.5429
C3H/HeJ f 2.625 0.2172 3.0526 2.1974
C3H/HeJ m 2.125 0.2172 2.5526 1.6974
C57BL/10J f 2.8333 0.2508 3.327 2.3396
C57BL/10J m 2.8571 0.2322 3.3142 2.4001
C57BL/6J f 3.0 0.2322 3.4571 2.5429
C57BL/6J m 2.625 0.2172 3.0526 2.1974
C57BLKS/J f 1.75 0.2172 2.1776 1.3224
C57BLKS/J m 1.875 0.2172 2.3026 1.4474
C57BR/cdJ f 2.125 0.2172 2.5526 1.6974
C57BR/cdJ m 1.5 0.2172 1.9276 1.0724
C57L/J f 2.7143 0.2322 3.1714 2.2572
C57L/J m 2.5714 0.1642 2.8946 2.2482
CBA/J f 2.5714 0.2322 3.0285 2.1144
CBA/J m 3.0 0.2322 3.4571 2.5429
DBA/2J f 2.6667 0.2508 3.1604 2.173
DBA/2J m 3.0 0.2322 3.4571 2.5429
FVB/NJ f 2.2857 0.2322 2.7428 1.8286
FVB/NJ m 1.5 0.3072 2.1047 0.8953
KK/HlJ f 1.625 0.2172 2.0526 1.1974
KK/HlJ m 2.7143 0.2322 3.1714 2.2572
LP/J f 3.0 0.2172 3.4276 2.5724
LP/J m 3.0 0.2172 3.4276 2.5724
MRL/MpJ f 2.7143 0.2322 3.1714 2.2572
MRL/MpJ m 2.625 0.2172 3.0526 2.1974
NOD.B10Sn-H2b/J f 3.0 0.2748 3.5408 2.4592
NOD.B10Sn-H2b/J m 3.0 0.2508 3.4937 2.5063
NZO/HlLtJ f 2.8333 0.2508 3.327 2.3396
NZO/HlLtJ m 1.5 0.4345 2.3551 0.6449
NZW/LacJ f 2.625 0.2172 3.0526 2.1974
NZW/LacJ m 2.5 0.2508 2.9937 2.0063
PWD/PhJ f 2.8333 0.2508 3.327 2.3396
PWD/PhJ m 2.8571 0.2322 3.3142 2.4001
RIIIS/J f 1.8571 0.2322 2.3142 1.4001
RIIIS/J m 2.75 0.3072 3.3547 2.1453
SM/J f 2.6667 0.2508 3.1604 2.173
SM/J m 2.3333 0.2048 2.7364 1.9302
SWR/J f 2.75 0.3072 3.3547 2.1453
SWR/J m 3.0 0.2322 3.4571 2.5429
WSB/EiJ f 3.0 0.2172 3.4276 2.5724
WSB/EiJ m 3.0 0.3072 3.6047 2.3953


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.4554 0.159 1.7683 1.1424
A/J both 1.3542 0.1659 1.6807 1.0276
BALB/cByJ both 2.875 0.1659 3.2016 2.5484
BTBR T+ Itpr3tf/J both 2.9375 0.208 3.3469 2.5281
BUB/BnJ both 1.0 0.212 1.4173 0.5827
C3H/HeJ both 2.375 0.1536 2.6773 2.0727
C57BL/10J both 2.8452 0.1709 3.1816 2.5088
C57BL/6J both 2.8125 0.159 3.1254 2.4996
C57BLKS/J both 1.8125 0.1536 2.1148 1.5102
C57BR/cdJ both 1.8125 0.1536 2.1148 1.5102
C57L/J both 2.6429 0.1422 2.9228 2.363
CBA/J both 2.7857 0.1642 3.1089 2.4625
DBA/2J both 2.8333 0.1709 3.1697 2.4969
FVB/NJ both 1.8929 0.1926 2.2718 1.5139
KK/HlJ both 2.1696 0.159 2.4826 1.8567
LP/J both 3.0 0.1536 3.3023 2.6977
MRL/MpJ both 2.6696 0.159 2.9826 2.3567
NOD.B10Sn-H2b/J both 3.0 0.186 3.3661 2.6339
NZO/HlLtJ both 2.1667 0.2508 2.6604 1.673
NZW/LacJ both 2.5625 0.1659 2.8891 2.2359
PWD/PhJ both 2.8452 0.1709 3.1816 2.5088
RIIIS/J both 2.3036 0.1926 2.6826 1.9246
SM/J both 2.5 0.1619 2.8187 2.1813
SWR/J both 2.875 0.1926 3.254 2.496
WSB/EiJ both 3.0 0.1881 3.3703 2.6297




  GWAS USING LINEAR MIXED MODELS