Project measure / variable:   Koide2   capsaicin_10

ID, description, units MPD:35806   capsaicin_10   capsaicin solution consumption, percentage of baseline   [%]  concentration: 10 µM  
Data set, strains Koide2   wild-derived Mishima   14 strains     sex: both     age: 8-12wks
Procedure nociception assay
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  STRAIN COMPARISON PLOT
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Koide2 - capsaicin solution consumption, percentage of baseline concentration: 10 µM



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means37.4   % 37.6   %
Median of the strain means35.2   % 33.2   %
SD of the strain means± 19.9 ± 19.8
Coefficient of variation (CV)0.532 0.526
Min–max range of strain means11.2   –   79.9   % 7.47   –   63.7   %
Mean sample size per strain10.0   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.6637 2.6637 0.006 0.9386
strain 13 97184.8578 7475.7583 16.7121 < 0.0001
sex:strain 13 5413.0621 416.3894 0.9308 0.5215
Residuals 252 112725.8701 447.3249


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BALB/cAnN f 28.7 17.7   10 5.61 0.618 7.18, 57.4 -0.44
BALB/cAnN m 25.1 18.3   10 5.78 0.729 8.43, 57.4 -0.63
BFM/2Ms f 30.1 18.7   10 5.92 0.621 7.34, 53.4 -0.37
BFM/2Ms m 30.0 23.2   10 7.33 0.773 9.97, 78.1 -0.39
BLG2/Ms f 40.3 16.9   10 5.35 0.42 13.7, 64.4 0.14
BLG2/Ms m 57.3 9.53   10 3.01 0.166 34.4, 69.1 0.99
C57BL/6J f 12.6 14.4   10 4.54 1.14 4.78, 51.4 -1.25
C57BL/6J m 13.2 9.1   10 2.88 0.689 5.11, 29.6 -1.23
CAST/EiJ f 64.0 12.8   10 4.04 0.2 39.5, 88.0 1.33
CAST/EiJ m 62.6 27.3   10 8.64 0.436 9.29, 96.2 1.26
CHD/Ms f 46.1 28.9   10 9.14 0.627 11.8, 101.0 0.43
CHD/Ms m 38.7 21.9   10 6.92 0.566 9.0, 74.1 0.05
DBA/1J f 11.2 6.3   10 1.99 0.562 5.06, 27.3 -1.32
DBA/1J m 7.47 1.59   10 0.504 0.213 5.95, 10.4 -1.52
HMI/Ms f 36.1 31.0   10 9.8 0.858 8.11, 93.8 -0.07
HMI/Ms m 36.4 28.1   10 8.88 0.771 10.2, 90.4 -0.06
JF1/MsJ f 34.3 22.6   10 7.16 0.66 8.44, 65.0 -0.16
JF1/MsJ m 26.4 20.1   10 6.35 0.762 8.03, 70.1 -0.57
KJR/Ms f 79.9 20.2   10 6.39 0.253 40.5, 105.0 2.13
KJR/Ms m 61.4 20.5   10 6.49 0.334 29.3, 89.6 1.2
MSM/MsJ f 57.4 12.9   10 4.09 0.225 36.4, 76.1 1.0
MSM/MsJ m 63.7 36.3   10 11.5 0.571 29.3, 159.0 1.32
NJL/Ms f 22.1 18.5   10 5.84 0.837 5.44, 54.6 -0.77
NJL/Ms m 23.3 26.8   10 8.48 1.15 4.93, 86.8 -0.72
PGN2/Ms f 16.6 20.1   10 6.36 1.21 5.22, 72.9 -1.05
PGN2/Ms m 21.1 18.7   10 5.93 0.89 6.02, 54.4 -0.84
SWN/Ms f 44.7 31.1   10 9.82 0.695 6.34, 107.0 0.36
SWN/Ms m 60.3 17.1   10 5.41 0.284 22.9, 85.8 1.14


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN f 28.705 6.6882 41.877 15.533
BALB/cAnN m 25.083 6.6882 38.255 11.911
BFM/2Ms f 30.137 6.6882 43.309 16.965
BFM/2Ms m 29.977 6.6882 43.149 16.805
BLG2/Ms f 40.27 6.6882 53.442 27.098
BLG2/Ms m 57.29 6.6882 70.462 44.118
C57BL/6J f 12.565 6.6882 25.737 0.0
C57BL/6J m 13.2 6.6882 26.372 0.028
CAST/EiJ f 64.03 6.6882 77.202 50.858
CAST/EiJ m 62.599 6.6882 75.771 49.427
CHD/Ms f 46.12 6.6882 59.292 32.948
CHD/Ms m 38.69 6.6882 51.862 25.518
DBA/1J f 11.212 6.6882 24.384 0.0
DBA/1J m 7.472 6.6882 20.644 0.0
HMI/Ms f 36.114 6.6882 49.286 22.942
HMI/Ms m 36.42 6.6882 49.592 23.248
JF1/MsJ f 34.314 6.6882 47.486 21.142
JF1/MsJ m 26.363 6.6882 39.535 13.191
KJR/Ms f 79.89 6.6882 93.062 66.718
KJR/Ms m 61.44 6.6882 74.612 48.268
MSM/MsJ f 57.39 6.6882 70.562 44.218
MSM/MsJ m 63.67 6.6882 76.842 50.498
NJL/Ms f 22.062 6.6882 35.234 8.89
NJL/Ms m 23.27 6.6882 36.442 10.098
PGN2/Ms f 16.644 6.6882 29.816 3.472
PGN2/Ms m 21.076 6.6882 34.248 7.904
SWN/Ms f 44.656 6.6882 57.828 31.484
SWN/Ms m 60.29 6.6882 73.462 47.118


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN both 26.894 4.7293 36.208 17.58
BFM/2Ms both 30.057 4.7293 39.371 20.743
BLG2/Ms both 48.78 4.7293 58.094 39.466
C57BL/6J both 12.8825 4.7293 22.1965 3.5685
CAST/EiJ both 63.3145 4.7293 72.6285 54.0005
CHD/Ms both 42.405 4.7293 51.719 33.091
DBA/1J both 9.342 4.7293 18.656 0.028
HMI/Ms both 36.267 4.7293 45.581 26.953
JF1/MsJ both 30.3385 4.7293 39.6525 21.0245
KJR/Ms both 70.665 4.7293 79.979 61.351
MSM/MsJ both 60.53 4.7293 69.844 51.216
NJL/Ms both 22.666 4.7293 31.98 13.352
PGN2/Ms both 18.86 4.7293 28.174 9.546
SWN/Ms both 52.473 4.7293 61.787 43.159




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA