Project measure / variable:   Koide2   capsaicin_7

ID, description, units MPD:35805   capsaicin_7   capsaicin solution consumption, percentage of baseline   [%]  concentration: 7 µM  
Data set, strains Koide2   wild-derived Mishima   14 strains     sex: both     age: 8-12wks
Procedure nociception assay
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  STRAIN COMPARISON PLOT
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Koide2 - capsaicin solution consumption, percentage of baseline concentration: 7 µM



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means47.7   % 50.8   %
Median of the strain means46.4   % 50.7   %
SD of the strain means± 20.6 ± 20.4
Coefficient of variation (CV)0.431 0.401
Min–max range of strain means13.3   –   81.4   % 18.0   –   83.9   %
Mean sample size per strain10.0   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 665.4656 665.4656 1.1713 0.2802
strain 13 103929.8602 7994.6046 14.0714 < 0.0001
sex:strain 13 5126.4683 394.3437 0.6941 0.7686
Residuals 252 143172.504 568.1449


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BALB/cAnN f 38.7 13.3   10 4.22 0.345 16.5, 63.6 -0.44
BALB/cAnN m 39.0 21.0   10 6.63 0.538 10.4, 81.9 -0.58
BFM/2Ms f 43.7 15.1   10 4.78 0.346 14.0, 62.6 -0.19
BFM/2Ms m 49.3 19.3   10 6.09 0.39 16.4, 75.0 -0.07
BLG2/Ms f 57.0 11.4   10 3.6 0.2 44.0, 74.0 0.45
BLG2/Ms m 66.1 9.44   10 2.99 0.143 43.9, 76.1 0.75
C57BL/6J f 19.1 13.6   10 4.3 0.713 7.14, 49.0 -1.39
C57BL/6J m 22.5 14.8   10 4.67 0.656 5.42, 43.6 -1.39
CAST/EiJ f 81.4 18.2   10 5.75 0.223 51.5, 112.0 1.64
CAST/EiJ m 72.2 25.7   10 8.12 0.356 16.6, 108.0 1.05
CHD/Ms f 47.7 18.6   10 5.88 0.39 19.1, 70.4 0.0
CHD/Ms m 53.1 22.7   10 7.17 0.427 13.4, 75.1 0.11
DBA/1J f 13.3 10.6   10 3.35 0.8 6.91, 42.8 -1.67
DBA/1J m 18.0 13.8   10 4.35 0.766 7.9, 54.3 -1.61
HMI/Ms f 43.0 28.3   10 8.95 0.658 8.95, 96.2 -0.23
HMI/Ms m 52.1 27.7   10 8.75 0.531 7.33, 99.1 0.07
JF1/MsJ f 60.4 26.1   10 8.25 0.432 17.6, 109.0 0.62
JF1/MsJ m 63.6 63.3   10 20.0 0.994 14.9, 227.0 0.63
KJR/Ms f 74.6 11.8   10 3.72 0.158 47.0, 91.8 1.31
KJR/Ms m 78.5 16.0   10 5.07 0.204 51.0, 102.0 1.36
MSM/MsJ f 72.9 11.3   10 3.57 0.155 63.7, 101.0 1.22
MSM/MsJ m 83.9 46.3   10 14.7 0.552 51.5, 214.0 1.63
NJL/Ms f 48.5 28.0   10 8.84 0.577 12.1, 82.0 0.04
NJL/Ms m 29.1 21.0   10 6.63 0.722 8.71, 63.2 -1.06
PGN2/Ms f 22.5 11.5   10 3.63 0.511 10.1, 37.6 -1.22
PGN2/Ms m 39.4 13.7   10 4.34 0.348 7.14, 57.5 -0.56
SWN/Ms f 45.0 29.5   10 9.32 0.655 9.18, 76.2 -0.13
SWN/Ms m 44.0 24.2   10 7.65 0.55 10.9, 78.3 -0.33


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN f 38.68 7.5375 53.5246 23.8354
BALB/cAnN m 39.0 7.5375 53.8446 24.1554
BFM/2Ms f 43.7 7.5375 58.5446 28.8554
BFM/2Ms m 49.35 7.5375 64.1946 34.5054
BLG2/Ms f 56.97 7.5375 71.8146 42.1254
BLG2/Ms m 66.12 7.5375 80.9646 51.2754
C57BL/6J f 19.053 7.5375 33.8976 4.2084
C57BL/6J m 22.511 7.5375 37.3556 7.6664
CAST/EiJ f 81.4 7.5375 96.2446 66.5554
CAST/EiJ m 72.18 7.5375 87.0246 57.3354
CHD/Ms f 47.68 7.5375 62.5246 32.8354
CHD/Ms m 53.09 7.5375 67.9346 38.2454
DBA/1J f 13.258 7.5375 28.1026 0.0
DBA/1J m 17.97 7.5375 32.8146 3.1254
HMI/Ms f 43.004 7.5375 57.8486 28.1594
HMI/Ms m 52.073 7.5375 66.9176 37.2284
JF1/MsJ f 60.4 7.5375 75.2446 45.5554
JF1/MsJ m 63.63 7.5375 78.4746 48.7854
KJR/Ms f 74.63 7.5375 89.4746 59.7854
KJR/Ms m 78.46 7.5375 93.3046 63.6154
MSM/MsJ f 72.88 7.5375 87.7246 58.0354
MSM/MsJ m 83.91 7.5375 98.7546 69.0654
NJL/Ms f 48.48 7.5375 63.3246 33.6354
NJL/Ms m 29.061 7.5375 43.9056 14.2164
PGN2/Ms f 22.47 7.5375 37.3146 7.6254
PGN2/Ms m 39.414 7.5375 54.2586 24.5694
SWN/Ms f 44.988 7.5375 59.8326 30.1434
SWN/Ms m 43.99 7.5375 58.8346 29.1454


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN both 38.84 5.3298 49.3367 28.3433
BFM/2Ms both 46.525 5.3298 57.0217 36.0283
BLG2/Ms both 61.545 5.3298 72.0417 51.0483
C57BL/6J both 20.782 5.3298 31.2787 10.2853
CAST/EiJ both 76.79 5.3298 87.2867 66.2933
CHD/Ms both 50.385 5.3298 60.8817 39.8883
DBA/1J both 15.614 5.3298 26.1107 5.1173
HMI/Ms both 47.5385 5.3298 58.0352 37.0418
JF1/MsJ both 62.015 5.3298 72.5117 51.5183
KJR/Ms both 76.545 5.3298 87.0417 66.0483
MSM/MsJ both 78.395 5.3298 88.8917 67.8983
NJL/Ms both 38.7705 5.3298 49.2672 28.2738
PGN2/Ms both 30.942 5.3298 41.4387 20.4453
SWN/Ms both 44.489 5.3298 54.9857 33.9923




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA