Project measure / variable:   Koide2   capsaicin_05

ID, description, units MPD:35802   capsaicin_05   capsaicin solution consumption, percentage of baseline   [%]  concentration: 0.5 µM  
Data set, strains Koide2   wild-derived Mishima   14 strains     sex: both     age: 8-12wks
Procedure nociception assay
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  STRAIN COMPARISON PLOT
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Koide2 - capsaicin solution consumption, percentage of baseline concentration: 0.5 µM



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means85.1   % 86.7   %
Median of the strain means88.5   % 87.5   %
SD of the strain means± 13.0 ± 16.6
Coefficient of variation (CV)0.153 0.191
Min–max range of strain means56.2   –   103   % 61.5   –   117   %
Mean sample size per strain10.0   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 180.0009 180.0009 0.1939 0.6601
strain 13 49861.2742 3835.4826 4.1311 < 0.0001
sex:strain 13 7867.8856 605.222 0.6519 0.8085
Residuals 252 233966.719 928.4394


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BALB/cAnN f 67.8 23.7   10 7.51 0.35 14.8, 98.0 -1.33
BALB/cAnN m 61.5 25.3   10 8.0 0.411 16.2, 92.1 -1.52
BFM/2Ms f 77.1 15.1   10 4.78 0.196 53.6, 102.0 -0.61
BFM/2Ms m 84.2 19.9   10 6.28 0.236 46.8, 111.0 -0.15
BLG2/Ms f 86.2 11.3   10 3.58 0.131 69.0, 104.0 0.09
BLG2/Ms m 91.8 5.18   10 1.64 0.0564 80.5, 99.1 0.31
C57BL/6J f 75.3 33.0   10 10.4 0.439 30.1, 146.0 -0.75
C57BL/6J m 62.5 21.6   10 6.82 0.345 35.5, 93.7 -1.46
CAST/EiJ f 94.3 14.1   10 4.45 0.149 71.4, 117.0 0.71
CAST/EiJ m 99.8 23.4   10 7.39 0.234 52.6, 148.0 0.79
CHD/Ms f 79.5 23.0   10 7.26 0.289 16.8, 94.4 -0.43
CHD/Ms m 78.1 21.6   10 6.83 0.276 49.0, 112.0 -0.52
DBA/1J f 56.2 21.7   10 6.85 0.386 16.7, 80.7 -2.22
DBA/1J m 65.5 12.0   10 3.81 0.184 42.7, 80.8 -1.28
HMI/Ms f 102.0 12.0   10 3.79 0.118 91.5, 130.0 1.3
HMI/Ms m 117.0 116.0   10 36.8 0.994 14.6, 438.0 1.83
JF1/MsJ f 92.7 13.8   10 4.36 0.149 71.4, 116.0 0.58
JF1/MsJ m 87.4 36.4   10 11.5 0.416 43.4, 171.0 0.04
KJR/Ms f 91.5 27.6   10 8.72 0.301 19.9, 122.0 0.49
KJR/Ms m 95.8 4.78   10 1.51 0.0499 87.8, 103.0 0.55
MSM/MsJ f 90.7 13.1   10 4.14 0.144 69.5, 119.0 0.43
MSM/MsJ m 110.0 47.9   10 15.2 0.436 79.6, 242.0 1.41
NJL/Ms f 103.0 12.0   10 3.79 0.116 82.1, 124.0 1.38
NJL/Ms m 80.1 19.9   10 6.29 0.248 47.4, 104.0 -0.4
PGN2/Ms f 82.4 11.7   10 3.7 0.142 61.2, 97.6 -0.21
PGN2/Ms m 87.6 10.2   10 3.21 0.116 71.2, 104.0 0.06
SWN/Ms f 92.4 24.1   10 7.63 0.261 51.4, 145.0 0.56
SWN/Ms m 92.2 17.7   10 5.6 0.192 58.8, 124.0 0.33


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN f 67.78 9.6356 86.7565 48.8035
BALB/cAnN m 61.52 9.6356 80.4965 42.5435
BFM/2Ms f 77.08 9.6356 96.0565 58.1035
BFM/2Ms m 84.17 9.6356 103.1465 65.1935
BLG2/Ms f 86.17 9.6356 105.1465 67.1935
BLG2/Ms m 91.79 9.6356 110.7665 72.8135
C57BL/6J f 75.35 9.6356 94.3265 56.3735
C57BL/6J m 62.49 9.6356 81.4665 43.5135
CAST/EiJ f 94.32 9.6356 113.2965 75.3435
CAST/EiJ m 99.8 9.6356 118.7765 80.8235
CHD/Ms f 79.51 9.6356 98.4865 60.5335
CHD/Ms m 78.09 9.6356 97.0665 59.1135
DBA/1J f 56.21 9.6356 75.1865 37.2335
DBA/1J m 65.46 9.6356 84.4365 46.4835
HMI/Ms f 101.83 9.6356 120.8065 82.8535
HMI/Ms m 117.02 9.6356 135.9965 98.0435
JF1/MsJ f 92.65 9.6356 111.6265 73.6735
JF1/MsJ m 87.43 9.6356 106.4065 68.4535
KJR/Ms f 91.52 9.6356 110.4965 72.5435
KJR/Ms m 95.8 9.6356 114.7765 76.8235
MSM/MsJ f 90.66 9.6356 109.6365 71.6835
MSM/MsJ m 109.94 9.6356 128.9165 90.9635
NJL/Ms f 103.13 9.6356 122.1065 84.1535
NJL/Ms m 80.11 9.6356 99.0865 61.1335
PGN2/Ms f 82.39 9.6356 101.3665 63.4135
PGN2/Ms m 87.64 9.6356 106.6165 68.6635
SWN/Ms f 92.41 9.6356 111.3865 73.4335
SWN/Ms m 92.2 9.6356 111.1765 73.2235


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN both 64.65 6.8134 78.0684 51.2316
BFM/2Ms both 80.625 6.8134 94.0434 67.2066
BLG2/Ms both 88.98 6.8134 102.3984 75.5616
C57BL/6J both 68.92 6.8134 82.3384 55.5016
CAST/EiJ both 97.06 6.8134 110.4784 83.6416
CHD/Ms both 78.8 6.8134 92.2184 65.3816
DBA/1J both 60.835 6.8134 74.2534 47.4166
HMI/Ms both 109.425 6.8134 122.8434 96.0066
JF1/MsJ both 90.04 6.8134 103.4584 76.6216
KJR/Ms both 93.66 6.8134 107.0784 80.2416
MSM/MsJ both 100.3 6.8134 113.7184 86.8816
NJL/Ms both 91.62 6.8134 105.0384 78.2016
PGN2/Ms both 85.015 6.8134 98.4334 71.5966
SWN/Ms both 92.305 6.8134 105.7234 78.8866




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA