Project measure / variable:   Lightfoot1   activity_speed

ID, description, units MPD:35703   activity_speed   wheel running activity, mean speed   [m/min]  
Data set, strains Lightfoot1   inbred   41 strains     sex: both     age: 8-16wks
Procedure running wheel monitoring
Ontology mappings

  STRAIN COMPARISON PLOT
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Lightfoot1 - wheel running activity, mean speed



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested41 strains41 strains
Mean of the strain means25.1   m/min 23.0   m/min
Median of the strain means25.5   m/min 23.7   m/min
SD of the strain means± 5.50 ± 6.92
Coefficient of variation (CV)0.219 0.301
Min–max range of strain means14.4   –   40.9   m/min 6.41   –   36.4   m/min
Mean sample size per strain4.7   mice 5.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 748.9388 748.9388 41.7459 < 0.0001
strain 40 15595.8924 389.8973 21.7329 < 0.0001
sex:strain 40 2116.7113 52.9178 2.9496 < 0.0001
Residuals 366 6566.1913 17.9404


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 15.5 2.14   5 0.957 0.138 13.1, 17.6 -1.75
129S1/SvImJ m 20.9 8.96   5 4.01 0.428 10.3, 30.0 -0.3
129T2/SvEmsJ f 21.0 11.0   3 6.35 0.525 12.9, 33.5 -0.75
129T2/SvEmsJ m 17.0 5.82   3 3.36 0.343 11.5, 23.1 -0.86
129X1/SvJ f 31.1 3.73   3 2.15 0.12 28.8, 35.4 1.09
129X1/SvJ m 29.5 2.21   3 1.28 0.0751 27.9, 32.0 0.95
A/J f 23.7 7.77   4 3.88 0.328 12.8, 30.6 -0.26
A/J m 15.0 1.3   5 0.579 0.0861 14.1, 17.2 -1.15
AKR/J f 25.5 1.73   5 0.775 0.0679 22.5, 26.6 0.07
AKR/J m 15.4 0.891   5 0.398 0.058 14.5, 16.4 -1.09
BALB/cByJ f 27.0 2.95   3 1.71 0.109 24.6, 30.3 0.34
BALB/cByJ m 24.3 5.4   3 3.12 0.222 19.0, 29.8 0.19
BALB/cJ f 21.9 2.25   15 0.581 0.103 17.1, 26.7 -0.59
BALB/cJ m 19.9 3.28   14 0.876 0.164 15.4, 24.6 -0.44
BTBR T+ Itpr3tf/J f 14.4 2.1   3 1.21 0.146 12.6, 16.7 -1.95
BTBR T+ Itpr3tf/J m 27.7 1.17   3 0.674 0.0421 26.7, 29.0 0.69
BUB/BnJ f 23.8 3.29   3 1.9 0.138 20.0, 25.8 -0.24
BUB/BnJ m 22.3 4.8   3 2.77 0.215 17.5, 27.1 -0.09
C3HeB/FeJ f 21.3 1.15   5 0.513 0.0538 19.8, 22.7 -0.7
C3HeB/FeJ m 12.8 1.55   5 0.693 0.121 11.4, 15.4 -1.47
C3H/HeJ f 17.9 1.3   5 0.583 0.073 16.2, 19.8 -1.32
C3H/HeJ m 12.3 2.02   23 0.421 0.164 8.44, 16.6 -1.54
C57BL/10J f 28.1 2.64   5 1.18 0.094 24.9, 32.1 0.54
C57BL/10J m 26.8 4.28   5 1.91 0.16 20.8, 32.1 0.56
C57BL/6J f 32.1 3.24   28 0.613 0.101 24.6, 39.0 1.27
C57BL/6J m 31.4 6.05   36 1.01 0.193 15.1, 37.8 1.22
C57BLKS/J f 22.2 5.34   5 2.39 0.24 12.8, 25.6 -0.53
C57BLKS/J m 15.7 10.8   5 4.84 0.691 -1.05
C57BR/cdJ f 34.9 0.52   3 0.3 0.0149 34.6, 35.5 1.78
C57BR/cdJ m 35.5 4.08   3 2.35 0.115 32.9, 40.2 1.81
C57L/J f 32.9 2.13   11 0.643 0.0648 30.8, 37.1 1.41
C57L/J m 28.5 5.23   16 1.31 0.183 18.3, 35.5 0.8
C58/J f 16.6 0.0577   3 0.0333 0.00347 16.6, 16.7 -1.55
C58/J m 16.6 0.0577   3 0.0333 0.00347 16.6, 16.7 -0.92
CAST/EiJ f 25.3 2.6   10 0.824 0.103 22.1, 29.3 0.03
CAST/EiJ m 23.7 3.79   10 1.2 0.16 18.7, 28.9 0.11
CBA/J f 23.2 1.98   5 0.887 0.0856 20.7, 25.8 -0.35
CBA/J m 19.6 1.79   5 0.8 0.0913 17.2, 21.3 -0.48
CE/J f 30.1 3.6   5 1.61 0.12 27.1, 34.3 0.9
CE/J m 27.2 4.23   5 1.89 0.156 22.8, 31.6 0.61
DBA/1J f 28.2 7.93   3 4.58 0.281 19.1, 33.3 0.56
DBA/1J m 28.3 5.26   3 3.04 0.186 22.3, 32.1 0.77
DBA/2J f 25.9 2.78   5 1.24 0.107 23.8, 30.6 0.14
DBA/2J m 16.9 0.865   5 0.387 0.0511 16.0, 18.0 -0.87
FVB/NJ f 29.6 4.61   3 2.66 0.156 24.4, 33.1 0.81
FVB/NJ m 29.4 2.31   3 1.33 0.0785 28.1, 32.1 0.93
I/LnJ f 22.5 2.34   3 1.35 0.104 19.8, 24.0 -0.48
I/LnJ m 24.9 0.636   2   0.45 0.0255 24.5, 25.4 0.28
KK/HlJ f 26.1 2.41   3 1.39 0.0922 23.8, 28.6 0.18
KK/HlJ m 22.6 1.91   3 1.1 0.0844 20.8, 24.6 -0.05
LG/J f 26.0 3.29   3 1.9 0.126 22.4, 28.8 0.16
LG/J m 23.7 6.61   3 3.82 0.279 16.1, 27.6 0.11
LP/J f 19.5 6.38   5 2.85 0.328 14.4, 30.3 -1.03
LP/J m 25.3 2.8   5 1.25 0.111 22.0, 28.1 0.34
MOLF/EiJ f 28.3 5.23   2   3.7 0.185 24.6, 32.0 0.58
MOLF/EiJ m 31.3 1.56   2   1.1 0.0497 30.2, 32.4 1.21
MRL/MpJ f 18.9 0.971   5 0.434 0.0513 17.7, 20.1 -1.13
MRL/MpJ m 20.5 2.85   4 1.42 0.139 16.8, 23.2 -0.35
NOD/ShiLtJ f 30.5 15.5   3 8.95 0.509 12.6, 40.3 0.98
NOD/ShiLtJ m 31.9 1.9   3 1.1 0.0597 29.9, 33.7 1.29
NON/ShiLtJ f 28.1 0.252   3 0.145 0.00897 27.8, 28.3 0.54
NON/ShiLtJ m 27.4 1.78   3 1.03 0.065 25.8, 29.3 0.64
NZB/BlNJ f 21.6 3.58   10 1.13 0.166 15.2, 29.1 -0.64
NZB/BlNJ m 20.5 2.08   5 0.931 0.102 17.9, 22.5 -0.35
NZW/LacJ f 25.7 2.35   3 1.36 0.0917 23.4, 28.1 0.1
NZW/LacJ m 20.3 3.01   3 1.74 0.148 17.0, 22.9 -0.38
PL/J f 18.3 3.59   5 1.61 0.196 15.0, 23.6 -1.24
PL/J m 23.3 2.98   5 1.33 0.128 18.9, 26.7 0.05
PWD/PhJ f 40.9 5.74   3 3.32 0.141 37.5, 47.5 2.87
PWD/PhJ m 36.4 6.99   3 4.04 0.192 28.5, 41.8 1.94
RIIIS/J f 30.1 0.681   3 0.393 0.0226 29.3, 30.6 0.9
RIIIS/J m 32.8 3.03   3 1.75 0.0925 29.3, 34.7 1.42
SJL/J f 21.1 6.72   3 3.88 0.318 13.4, 25.5 -0.73
SJL/J m 9.01 3.49   3 2.01 0.387 5.53, 12.5 -2.02
SM/J f 25.0 0.981   5 0.439 0.0393 23.6, 26.2 -0.02
SM/J m 24.1 5.85   5 2.61 0.243 13.7, 27.8 0.17
SPRET/EiJ f 26.9 5.84   5 2.61 0.217 17.1, 32.0 0.32
SPRET/EiJ m 24.1 1.8   5 0.807 0.0748 22.4, 26.6 0.17
SWR/J f 28.3 2.4   5 1.07 0.0846 25.0, 30.8 0.58
SWR/J m 19.8 0.965   5 0.432 0.0488 18.3, 20.9 -0.46
WSB/EiJ f 20.6 2.2   3 1.27 0.107 18.4, 22.8 -0.83
WSB/EiJ m 6.41 6.78   3 3.91 1.06 -2.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 15.52 1.8942 19.2449 11.7951
129S1/SvImJ m 20.94 1.8942 24.6649 17.2151
129T2/SvEmsJ f 20.9667 2.4454 25.7755 16.1578
129T2/SvEmsJ m 17.0 2.4454 21.8089 12.1911
129X1/SvJ f 31.1 2.4454 35.9089 26.2911
129X1/SvJ m 29.4667 2.4454 34.2755 24.6578
A/J f 23.7 2.1178 27.8646 19.5354
A/J m 15.04 1.8942 18.7649 11.3151
AKR/J f 25.52 1.8942 29.2449 21.7951
AKR/J m 15.36 1.8942 19.0849 11.6351
BALB/cByJ f 27.0 2.4454 31.8089 22.1911
BALB/cByJ m 24.3333 2.4454 29.1422 19.5245
BALB/cJ f 21.8867 1.0936 24.0373 19.7361
BALB/cJ m 19.9429 1.132 22.1689 17.7168
BTBR T+ Itpr3tf/J f 14.4 2.4454 19.2089 9.5911
BTBR T+ Itpr3tf/J m 27.7333 2.4454 32.5422 22.9245
BUB/BnJ f 23.8 2.4454 28.6089 18.9911
BUB/BnJ m 22.3333 2.4454 27.1422 17.5245
C3HeB/FeJ f 21.32 1.8942 25.0449 17.5951
C3HeB/FeJ m 12.82 1.8942 16.5449 9.0951
C3H/HeJ f 17.86 1.8942 21.5849 14.1351
C3H/HeJ m 12.323 0.8832 14.0598 10.5863
C57BL/10J f 28.06 1.8942 31.7849 24.3351
C57BL/10J m 26.82 1.8942 30.5449 23.0951
C57BL/6J f 32.1071 0.8005 33.6812 30.5331
C57BL/6J m 31.4167 0.7059 32.8049 30.0285
C57BLKS/J f 22.2 1.8942 25.9249 18.4751
C57BLKS/J m 15.66 1.8942 19.3849 11.9351
C57BR/cdJ f 34.9 2.4454 39.7089 30.0911
C57BR/cdJ m 35.5 2.4454 40.3089 30.6911
C57L/J f 32.9273 1.2771 35.4386 30.4159
C57L/J m 28.4875 1.0589 30.5698 26.4052
C58/J f 16.6333 2.4454 21.4422 11.8245
C58/J m 16.6333 2.4454 21.4422 11.8245
CAST/EiJ f 25.31 1.3394 27.9439 22.6761
CAST/EiJ m 23.69 1.3394 26.3239 21.0561
CBA/J f 23.18 1.8942 26.9049 19.4551
CBA/J m 19.58 1.8942 23.3049 15.8551
CE/J f 30.12 1.8942 33.8449 26.3951
CE/J m 27.16 1.8942 30.8849 23.4351
DBA/1J f 28.2333 2.4454 33.0422 23.4245
DBA/1J m 28.3 2.4454 33.1089 23.4911
DBA/2J f 25.9 1.8942 29.6249 22.1751
DBA/2J m 16.94 1.8942 20.6649 13.2151
FVB/NJ f 29.6333 2.4454 34.4422 24.8245
FVB/NJ m 29.4333 2.4454 34.2422 24.6245
I/LnJ f 22.5 2.4454 27.3089 17.6911
I/LnJ m 24.95 2.995 30.8396 19.0604
KK/HlJ f 26.1 2.4454 30.9089 21.2911
KK/HlJ m 22.6 2.4454 27.4089 17.7911
LG/J f 26.0333 2.4454 30.8422 21.2245
LG/J m 23.7333 2.4454 28.5422 18.9245
LP/J f 19.48 1.8942 23.2049 15.7551
LP/J m 25.32 1.8942 29.0449 21.5951
MOLF/EiJ f 28.3 2.995 34.1896 22.4104
MOLF/EiJ m 31.3 2.995 37.1896 25.4104
MRL/MpJ f 18.92 1.8942 22.6449 15.1951
MRL/MpJ m 20.5 2.1178 24.6646 16.3354
NOD/ShiLtJ f 30.4667 2.4454 35.2755 25.6578
NOD/ShiLtJ m 31.8667 2.4454 36.6755 27.0578
NON/ShiLtJ f 28.0667 2.4454 32.8755 23.2578
NON/ShiLtJ m 27.3667 2.4454 32.1755 22.5578
NZB/BlNJ f 21.58 1.3394 24.2139 18.9461
NZB/BlNJ m 20.48 1.8942 24.2049 16.7551
NZW/LacJ f 25.6667 2.4454 30.4755 20.8578
NZW/LacJ m 20.3 2.4454 25.1089 15.4911
PL/J f 18.3 1.8942 22.0249 14.5751
PL/J m 23.32 1.8942 27.0449 19.5951
PWD/PhJ f 40.8667 2.4454 45.6755 36.0578
PWD/PhJ m 36.4 2.4454 41.2089 31.5911
RIIIS/J f 30.0667 2.4454 34.8755 25.2578
RIIIS/J m 32.8 2.4454 37.6089 27.9911
SJL/J f 21.1333 2.4454 25.9422 16.3245
SJL/J m 9.0067 2.4454 13.8155 4.1978
SM/J f 24.98 1.8942 28.7049 21.2551
SM/J m 24.08 1.8942 27.8049 20.3551
SPRET/EiJ f 26.92 1.8942 30.6449 23.1951
SPRET/EiJ m 24.14 1.8942 27.8649 20.4151
SWR/J f 28.32 1.8942 32.0449 24.5951
SWR/J m 19.78 1.8942 23.5049 16.0551
WSB/EiJ f 20.6 2.4454 25.4089 15.7911
WSB/EiJ m 6.4133 2.4454 11.2222 1.6045


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 18.23 1.3394 20.8639 15.5961
129T2/SvEmsJ both 18.9833 1.7292 22.3837 15.583
129X1/SvJ both 30.2833 1.7292 33.6837 26.883
A/J both 19.37 1.4207 22.1637 16.5763
AKR/J both 20.44 1.3394 23.0739 17.8061
BALB/cByJ both 25.6667 1.7292 29.067 22.2663
BALB/cJ both 20.9148 0.787 22.4624 19.3671
BTBR T+ Itpr3tf/J both 21.0667 1.7292 24.467 17.6663
BUB/BnJ both 23.0667 1.7292 26.467 19.6663
C3HeB/FeJ both 17.07 1.3394 19.7039 14.4361
C3H/HeJ both 15.0915 1.045 17.1465 13.0366
C57BL/10J both 27.44 1.3394 30.0739 24.8061
C57BL/6J both 31.7619 0.5336 32.8113 30.7125
C57BLKS/J both 18.93 1.3394 21.5639 16.2961
C57BR/cdJ both 35.2 1.7292 38.6004 31.7996
C57L/J both 30.7074 0.8295 32.3386 29.0762
C58/J both 16.6333 1.7292 20.0337 13.233
CAST/EiJ both 24.5 0.9471 26.3625 22.6375
CBA/J both 21.38 1.3394 24.0139 18.7461
CE/J both 28.64 1.3394 31.2739 26.0061
DBA/1J both 28.2667 1.7292 31.667 24.8663
DBA/2J both 21.42 1.3394 24.0539 18.7861
FVB/NJ both 29.5333 1.7292 32.9337 26.133
I/LnJ both 23.725 1.9333 27.5267 19.9233
KK/HlJ both 24.35 1.7292 27.7504 20.9496
LG/J both 24.8833 1.7292 28.2837 21.483
LP/J both 22.4 1.3394 25.0339 19.7661
MOLF/EiJ both 29.8 2.1178 33.9646 25.6354
MRL/MpJ both 19.71 1.4207 22.5037 16.9163
NOD/ShiLtJ both 31.1667 1.7292 34.567 27.7663
NON/ShiLtJ both 27.7167 1.7292 31.117 24.3163
NZB/BlNJ both 21.03 1.16 23.311 18.749
NZW/LacJ both 22.9833 1.7292 26.3837 19.583
PL/J both 20.81 1.3394 23.4439 18.1761
PWD/PhJ both 38.6333 1.7292 42.0337 35.233
RIIIS/J both 31.4333 1.7292 34.8337 28.033
SJL/J both 15.07 1.7292 18.4704 11.6696
SM/J both 24.53 1.3394 27.1639 21.8961
SPRET/EiJ both 25.53 1.3394 28.1639 22.8961
SWR/J both 24.05 1.3394 26.6839 21.4161
WSB/EiJ both 13.5067 1.7292 16.907 10.1063




  GWAS USING LINEAR MIXED MODELS