Project measure / variable:   Lightfoot1   activity_distance

ID, description, units MPD:35701   activity_distance   wheel running activity, mean distance   [km/d]  
Data set, strains Lightfoot1   inbred   41 strains     sex: both     age: 8-16wks
Procedure running wheel monitoring
Ontology mappings

  STRAIN COMPARISON PLOT
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Lightfoot1 - wheel running activity, mean distance



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested41 strains41 strains
Mean of the strain means6.00   km/d 4.86   km/d
Median of the strain means5.42   km/d 5.27   km/d
SD of the strain means± 3.34 ± 2.78
Coefficient of variation (CV)0.557 0.572
Min–max range of strain means0.437   –   12.9   km/d 0.0333   –   9.87   km/d
Mean sample size per strain4.7   mice 5.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 163.851 163.851 31.3452 < 0.0001
strain 40 3508.6751 87.7169 16.7805 < 0.0001
sex:strain 40 440.6128 11.0153 2.1073 0.0002
Residuals 366 1913.197 5.2273


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.678 0.576   5 0.258 0.85 0.09, 1.37 -1.59
129S1/SvImJ m 0.122 0.246   5 0.11 2.01 -1.71
129T2/SvEmsJ f 2.26 3.46   3 2.0 1.53 0.01, 6.25 -1.12
129T2/SvEmsJ m 0.89 1.1   3 0.635 1.24 0.03, 2.13 -1.43
129X1/SvJ f 10.5 3.33   3 1.93 0.316 7.94, 14.3 1.35
129X1/SvJ m 5.28 1.08   3 0.623 0.204 4.12, 6.25 0.15
A/J f 6.43 4.46   4 2.23 0.693 0.32, 11.0 0.13
A/J m 5.27 1.29   5 0.576 0.244 4.34, 7.34 0.15
AKR/J f 4.4 0.594   5 0.266 0.135 3.66, 5.03 -0.48
AKR/J m 2.86 0.539   5 0.241 0.188 2.13, 3.57 -0.72
BALB/cByJ f 9.27 0.809   3 0.467 0.0873 8.76, 10.2 0.98
BALB/cByJ m 5.39 4.6   3 2.65 0.852 0.8, 9.99 0.19
BALB/cJ f 5.1 1.33   15 0.345 0.262 1.85, 6.91 -0.27
BALB/cJ m 5.22 1.57   14 0.421 0.301 2.5, 7.23 0.13
BTBR T+ Itpr3tf/J f 0.437 0.637   3 0.368 1.46 0.02, 1.17 -1.66
BTBR T+ Itpr3tf/J m 6.18 1.39   3 0.803 0.225 4.97, 7.7 0.48
BUB/BnJ f 4.98 4.59   3 2.65 0.922 0.96, 9.99 -0.3
BUB/BnJ m 3.13 3.73   3 2.15 1.19 0.84, 7.44 -0.62
C3HeB/FeJ f 6.92 1.91   5 0.853 0.276 4.85, 9.43 0.28
C3HeB/FeJ m 3.63 0.789   5 0.353 0.217 2.67, 4.45 -0.44
C3H/HeJ f 3.98 1.5   5 0.671 0.377 1.55, 5.61 -0.6
C3H/HeJ m 0.576 1.06   23 0.222 1.85 0.03, 4.63 -1.54
C57BL/10J f 5.7 2.11   5 0.946 0.371 2.48, 7.74 -0.09
C57BL/10J m 4.0 2.4   5 1.07 0.601 1.06, 7.47 -0.31
C57BL/6J f 8.38 2.61   28 0.492 0.311 2.88, 13.1 0.71
C57BL/6J m 6.77 2.63   36 0.439 0.389 2.06, 12.7 0.69
C57BLKS/J f 3.21 1.87   5 0.837 0.584 0.17, 4.94 -0.83
C57BLKS/J m 1.34 2.05   5 0.919 1.53 -1.27
C57BR/cdJ f 12.9 2.95   3 1.7 0.229 9.63, 15.4 2.07
C57BR/cdJ m 9.0 5.12   3 2.95 0.568 3.21, 12.9 1.49
C57L/J f 12.4 2.75   11 0.828 0.221 8.3, 16.0 1.92
C57L/J m 9.46 1.99   16 0.497 0.21 6.06, 12.3 1.66
C58/J f 10.2 1.3   3 0.748 0.127 8.79, 11.3 1.26
C58/J m 9.12 0.969   3 0.56 0.106 8.0, 9.74 1.54
CAST/EiJ f 5.54 3.32   10 1.05 0.6 0.37, 10.5 -0.14
CAST/EiJ m 3.97 2.66   10 0.84 0.669 0.81, 9.78 -0.32
CBA/J f 6.9 1.3   5 0.58 0.188 5.27, 7.9 0.27
CBA/J m 7.57 0.662   5 0.296 0.0875 7.08, 8.69 0.98
CE/J f 5.42 1.76   5 0.785 0.324 3.84, 8.16 -0.17
CE/J m 2.65 1.01   5 0.45 0.379 1.52, 3.77 -0.79
DBA/1J f 4.65 2.48   3 1.43 0.534 1.81, 6.41 -0.4
DBA/1J m 5.54 2.73   3 1.58 0.493 3.57, 8.66 0.25
DBA/2J f 3.78 1.07   5 0.48 0.284 2.49, 5.41 -0.66
DBA/2J m 3.97 1.0   5 0.449 0.253 2.43, 4.99 -0.32
FVB/NJ f 4.45 2.15   3 1.24 0.483 2.64, 6.83 -0.46
FVB/NJ m 6.28 2.83   3 1.63 0.45 3.82, 9.37 0.51
I/LnJ f 5.42 0.969   3 0.56 0.179 4.69, 6.52 -0.17
I/LnJ m 4.17 0.106   2   0.075 0.0254 4.1, 4.25 -0.25
KK/HlJ f 6.32 3.26   3 1.88 0.516 3.3, 9.78 0.1
KK/HlJ m 5.32 0.918   3 0.53 0.173 4.63, 6.36 0.17
LG/J f 10.2 2.47   3 1.42 0.241 7.42, 12.0 1.26
LG/J m 3.11 2.03   3 1.17 0.652 0.83, 4.71 -0.63
LP/J f 0.922 1.76   5 0.789 1.91 -1.52
LP/J m 5.7 2.28   5 1.02 0.4 3.45, 8.7 0.3
MOLF/EiJ f 6.76 1.98   2   1.4 0.293 5.36, 8.16 0.23
MOLF/EiJ m 6.83 0.354   2   0.25 0.0518 6.58, 7.08 0.71
MRL/MpJ f 4.81 1.86   5 0.831 0.386 1.54, 6.17 -0.36
MRL/MpJ m 5.24 0.705   4 0.353 0.135 4.64, 6.24 0.14
NOD/ShiLtJ f 10.8 9.12   3 5.26 0.845 0.87, 18.8 1.44
NOD/ShiLtJ m 9.87 1.09   3 0.629 0.11 8.62, 10.6 1.81
NON/ShiLtJ f 11.4 0.608   3 0.351 0.0534 10.7, 11.8 1.62
NON/ShiLtJ m 8.72 1.0   3 0.579 0.115 7.88, 9.83 1.39
NZB/BlNJ f 1.9 0.78   10 0.247 0.41 0.86, 3.27 -1.23
NZB/BlNJ m 2.35 1.18   5 0.526 0.501 0.67, 3.9 -0.9
NZW/LacJ f 2.15 1.16   3 0.669 0.538 1.22, 3.45 -1.15
NZW/LacJ m 0.827 0.709   3 0.409 0.857 0.01, 1.28 -1.45
PL/J f 2.57 2.02   5 0.902 0.785 0.42, 5.37 -1.03
PL/J m 3.51 1.73   5 0.771 0.491 1.06, 5.54 -0.48
PWD/PhJ f 11.6 3.07   3 1.77 0.266 8.05, 13.8 1.68
PWD/PhJ m 8.32 2.41   3 1.39 0.29 6.72, 11.1 1.25
RIIIS/J f 7.86 1.71   3 0.989 0.218 5.96, 9.29 0.56
RIIIS/J m 8.53 0.859   3 0.496 0.101 7.54, 9.07 1.32
SJL/J f 2.94 4.11   3 2.37 1.4 0.02, 7.64 -0.91
SJL/J m 0.0333 0.0115   3 0.00667 0.346 0.02, 0.04 -1.74
SM/J f 7.23 0.721   5 0.322 0.0996 6.27, 8.18 0.37
SM/J m 7.01 3.65   5 1.63 0.52 0.76, 9.97 0.78
SPRET/EiJ f 4.68 5.71   5 2.55 1.22 0.29, 13.7 -0.39
SPRET/EiJ m 5.99 1.88   5 0.84 0.314 3.49, 8.33 0.41
SWR/J f 7.32 2.28   5 1.02 0.312 3.67, 9.22 0.4
SWR/J m 5.28 0.925   5 0.413 0.175 3.88, 6.36 0.15
WSB/EiJ f 2.52 0.99   3 0.572 0.392 1.52, 3.5 -1.04
WSB/EiJ m 0.0367 0.0551   3 0.0318 1.5 -1.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.678 1.0225 2.6887 0.0
129S1/SvImJ m 0.122 1.0225 2.1327 0.0
129T2/SvEmsJ f 2.2633 1.32 4.8591 0.0
129T2/SvEmsJ m 0.89 1.32 3.4858 0.0
129X1/SvJ f 10.54 1.32 13.1358 7.9442
129X1/SvJ m 5.2833 1.32 7.8791 2.6876
A/J f 6.43 1.1432 8.678 4.182
A/J m 5.274 1.0225 7.2847 3.2633
AKR/J f 4.396 1.0225 6.4067 2.3853
AKR/J m 2.864 1.0225 4.8747 0.8533
BALB/cByJ f 9.2667 1.32 11.8624 6.6709
BALB/cByJ m 5.3933 1.32 7.9891 2.7976
BALB/cJ f 5.0993 0.5903 6.2602 3.9385
BALB/cJ m 5.2229 0.611 6.4245 4.0213
BTBR T+ Itpr3tf/J f 0.4367 1.32 3.0324 0.0
BTBR T+ Itpr3tf/J m 6.1833 1.32 8.7791 3.5876
BUB/BnJ f 4.9833 1.32 7.5791 2.3876
BUB/BnJ m 3.1333 1.32 5.7291 0.5376
C3HeB/FeJ f 6.916 1.0225 8.9267 4.9053
C3HeB/FeJ m 3.63 1.0225 5.6407 1.6193
C3H/HeJ f 3.978 1.0225 5.9887 1.9673
C3H/HeJ m 0.5761 0.4767 1.5136 0.0
C57BL/10J f 5.698 1.0225 7.7087 3.6873
C57BL/10J m 3.998 1.0225 6.0087 1.9873
C57BL/6J f 8.3793 0.4321 9.2289 7.5296
C57BL/6J m 6.7694 0.3811 7.5188 6.0201
C57BLKS/J f 3.206 1.0225 5.2167 1.1953
C57BLKS/J m 1.342 1.0225 3.3527 0.0
C57BR/cdJ f 12.8767 1.32 15.4724 10.2809
C57BR/cdJ m 9.0033 1.32 11.5991 6.4076
C57L/J f 12.4 0.6894 13.7556 11.0444
C57L/J m 9.4594 0.5716 10.5834 8.3354
C58/J f 10.23 1.32 12.8258 7.6342
C58/J m 9.1167 1.32 11.7124 6.5209
CAST/EiJ f 5.537 0.723 6.9588 4.1152
CAST/EiJ m 3.973 0.723 5.3948 2.5512
CBA/J f 6.904 1.0225 8.9147 4.8933
CBA/J m 7.566 1.0225 9.5767 5.5553
CE/J f 5.42 1.0225 7.4307 3.4093
CE/J m 2.654 1.0225 4.6647 0.6433
DBA/1J f 4.6467 1.32 7.2424 2.0509
DBA/1J m 5.54 1.32 8.1358 2.9442
DBA/2J f 3.776 1.0225 5.7867 1.7653
DBA/2J m 3.974 1.0225 5.9847 1.9633
FVB/NJ f 4.4533 1.32 7.0491 1.8576
FVB/NJ m 6.2833 1.32 8.8791 3.6876
I/LnJ f 5.42 1.32 8.0158 2.8242
I/LnJ m 4.175 1.6167 7.3541 0.9959
KK/HlJ f 6.3233 1.32 8.9191 3.7276
KK/HlJ m 5.3167 1.32 7.9124 2.7209
LG/J f 10.24 1.32 12.8358 7.6442
LG/J m 3.1133 1.32 5.7091 0.5176
LP/J f 0.922 1.0225 2.9327 0.0
LP/J m 5.704 1.0225 7.7147 3.6933
MOLF/EiJ f 6.76 1.6167 9.9391 3.5809
MOLF/EiJ m 6.83 1.6167 10.0091 3.6509
MRL/MpJ f 4.812 1.0225 6.8227 2.8013
MRL/MpJ m 5.2375 1.1432 7.4855 2.9895
NOD/ShiLtJ f 10.79 1.32 13.3858 8.1942
NOD/ShiLtJ m 9.8733 1.32 12.4691 7.2776
NON/ShiLtJ f 11.4 1.32 13.9958 8.8042
NON/ShiLtJ m 8.72 1.32 11.3158 6.1242
NZB/BlNJ f 1.902 0.723 3.3238 0.4802
NZB/BlNJ m 2.35 1.0225 4.3607 0.3393
NZW/LacJ f 2.1533 1.32 4.7491 0.0
NZW/LacJ m 0.8267 1.32 3.4224 0.0
PL/J f 2.57 1.0225 4.5807 0.5593
PL/J m 3.514 1.0225 5.5247 1.5033
PWD/PhJ f 11.55 1.32 14.1458 8.9542
PWD/PhJ m 8.3233 1.32 10.9191 5.7276
RIIIS/J f 7.8567 1.32 10.4524 5.2609
RIIIS/J m 8.53 1.32 11.1258 5.9342
SJL/J f 2.94 1.32 5.5358 0.3442
SJL/J m 0.0333 1.32 2.6291 0.0
SM/J f 7.234 1.0225 9.2447 5.2233
SM/J m 7.014 1.0225 9.0247 5.0033
SPRET/EiJ f 4.678 1.0225 6.6887 2.6673
SPRET/EiJ m 5.988 1.0225 7.9987 3.9773
SWR/J f 7.322 1.0225 9.3327 5.3113
SWR/J m 5.278 1.0225 7.2887 3.2673
WSB/EiJ f 2.5233 1.32 5.1191 0.0
WSB/EiJ m 0.0367 1.32 2.6324 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.4 0.723 1.8218 0.0
129T2/SvEmsJ both 1.5767 0.9334 3.4121 0.0
129X1/SvJ both 7.9117 0.9334 9.7471 6.0762
A/J both 5.852 0.7669 7.36 4.344
AKR/J both 3.63 0.723 5.0518 2.2082
BALB/cByJ both 7.33 0.9334 9.1655 5.4945
BALB/cJ both 5.1611 0.4248 5.9965 4.3257
BTBR T+ Itpr3tf/J both 3.31 0.9334 5.1455 1.4745
BUB/BnJ both 4.0583 0.9334 5.8938 2.2229
C3HeB/FeJ both 5.273 0.723 6.6948 3.8512
C3H/HeJ both 2.277 0.5641 3.3863 1.1678
C57BL/10J both 4.848 0.723 6.2698 3.4262
C57BL/6J both 7.5744 0.2881 8.1408 7.0079
C57BLKS/J both 2.274 0.723 3.6958 0.8522
C57BR/cdJ both 10.94 0.9334 12.7755 9.1045
C57L/J both 10.9297 0.4477 11.8102 10.0492
C58/J both 9.6733 0.9334 11.5088 7.8379
CAST/EiJ both 4.755 0.5112 5.7603 3.7497
CBA/J both 7.235 0.723 8.6568 5.8132
CE/J both 4.037 0.723 5.4588 2.6152
DBA/1J both 5.0933 0.9334 6.9288 3.2579
DBA/2J both 3.875 0.723 5.2968 2.4532
FVB/NJ both 5.3683 0.9334 7.2038 3.5329
I/LnJ both 4.7975 1.0436 6.8496 2.7454
KK/HlJ both 5.82 0.9334 7.6555 3.9845
LG/J both 6.6767 0.9334 8.5121 4.8412
LP/J both 3.313 0.723 4.7348 1.8912
MOLF/EiJ both 6.795 1.1432 9.043 4.547
MRL/MpJ both 5.0247 0.7669 6.5328 3.5167
NOD/ShiLtJ both 10.3317 0.9334 12.1671 8.4962
NON/ShiLtJ both 10.06 0.9334 11.8955 8.2245
NZB/BlNJ both 2.126 0.6261 3.3573 0.8947
NZW/LacJ both 1.49 0.9334 3.3255 0.0
PL/J both 3.042 0.723 4.4638 1.6202
PWD/PhJ both 9.9367 0.9334 11.7721 8.1012
RIIIS/J both 8.1933 0.9334 10.0288 6.3579
SJL/J both 1.4867 0.9334 3.3221 0.0
SM/J both 7.124 0.723 8.5458 5.7022
SPRET/EiJ both 5.333 0.723 6.7548 3.9112
SWR/J both 6.3 0.723 7.7218 4.8782
WSB/EiJ both 1.28 0.9334 3.1155 0.0




  GWAS USING LINEAR MIXED MODELS