Project measure / variable:   Palmer2   habituation_OFT

ID, description, units MPD:30004   habituation_OFT   change in activity from day 1 to day 2, habituation   [cm]  
methamphetamine study
Data set, strains Palmer2   B6.A consomic w/par   21 strains     sex: both     age: 7-16wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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Palmer2 - change in activity from day 1 to day 2, habituation



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means1170   cm 1045   cm
Median of the strain means1183   cm 1132   cm
SD of the strain means± 622 ± 514
Coefficient of variation (CV)0.532 0.492
Min–max range of strain means-420   –   2227   cm -370   –   1760   cm
Mean sample size per strain10.4   mice 11.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3971950.9972 3971950.9972 3.0643 0.0806
strain 20 117030427.7445 5851521.3872 4.5144 < 0.0001
sex:strain 20 22003728.6375 1100186.4319 0.8488 0.6535
Residuals 497 644209780.7358 1296196.7419


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f -420.0 621.0   9 207.0 -1.48 -1233.0, 368.0 -2.55
A/J m -370.0 1110.0   10 351.0 -3.0 -3090.0, 881.0 -2.75
B6.A-Chr1 f 462.0 1205.0   4 603.0 2.61 -1174.0, 1698.0 -1.14
B6.A-Chr1 m 730.0 544.0   6 222.0 0.746 -119.0, 1444.0 -0.61
B6.A-Chr10 f 1325.0 879.0   13 244.0 0.663 500.0, 3195.0 0.25
B6.A-Chr10 m 994.0 1001.0   16 250.0 1.01 -1535.0, 3137.0 -0.1
B6.A-Chr11 f 2227.0 1281.0   14 342.0 0.575 -273.0, 5121.0 1.7
B6.A-Chr11 m 1275.0 1104.0   23 230.0 0.866 -956.0, 3403.0 0.45
B6.A-Chr12 f 947.0 543.0   15 140.0 0.573 -241.0, 1727.0 -0.36
B6.A-Chr12 m 852.0 859.0   34 147.0 1.01 -1604.0, 2450.0 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f -420.0 379.5021 325.6263 -1165.6263
A/J m -369.7 360.0273 337.6632 -1077.0632
B6.A-Chr1 f 462.0 569.2532 1580.4394 -656.4394
B6.A-Chr1 m 729.6667 464.7933 1642.8686 -183.5353
B6.A-Chr10 f 1325.3077 315.7649 1945.7062 704.9091
B6.A-Chr10 m 994.4375 284.6266 1553.6572 435.2178
B6.A-Chr11 f 2226.8571 304.2786 2824.6881 1629.0261
B6.A-Chr11 m 1274.8261 237.395 1741.2476 808.4046
B6.A-Chr12 f 947.4 293.9611 1524.9596 369.8404
B6.A-Chr12 m 852.1471 195.2522 1235.7686 468.5255
B6.A-Chr14 f 389.8889 379.5021 1135.5152 -355.7374
B6.A-Chr14 m 1131.6 509.1555 2131.9626 131.2374
B6.A-Chr15 f 1165.3 360.0273 1872.6632 457.9368
B6.A-Chr15 m 250.3077 315.7649 870.7062 -370.0909
B6.A-Chr16 f 1567.3077 315.7649 2187.7062 946.9091
B6.A-Chr16 m 1102.5556 379.5021 1848.1818 356.9293
B6.A-Chr17 f 1198.0 657.317 2489.4626 -93.4626
B6.A-Chr17 m 1399.4444 379.5021 2145.0707 653.8182
B6.A-Chr18 f 1602.8 509.1555 2603.1626 602.4374
B6.A-Chr18 m 1725.3333 379.5021 2470.9596 979.7071
B6.A-Chr19 f 1539.4 360.0273 2246.7632 832.0368
B6.A-Chr19 m 1760.1 360.0273 2467.4632 1052.7368
B6.A-Chr2 f 777.0 360.0273 1484.3632 69.6368
B6.A-Chr2 m 591.3 360.0273 1298.6632 -116.0632
B6.A-Chr3 f 2181.25 402.5228 2972.1061 1390.3939
B6.A-Chr3 m 1459.2143 304.2786 2057.0453 861.3833
B6.A-Chr4 f 1128.3 360.0273 1835.6632 420.9368
B6.A-Chr4 m 1438.3333 379.5021 2183.9596 692.7071
B6.A-Chr5 f 1182.7143 304.2786 1780.5453 584.8833
B6.A-Chr5 m 1147.3 360.0273 1854.6632 439.9368
B6.A-Chr6 f 649.6 360.0273 1356.9632 -57.7632
B6.A-Chr6 m 674.2222 379.5021 1419.8485 -71.404
B6.A-Chr7 f 681.5 360.0273 1388.8632 -25.8632
B6.A-Chr7 m 616.4545 343.2726 1290.8989 -57.9898
B6.A-Chr8 f 1843.0833 328.6585 2488.8146 1197.352
B6.A-Chr8 m 944.625 402.5228 1735.4811 153.7689
B6.A-Chr9 f 1576.2 360.0273 2283.5632 868.8368
B6.A-Chr9 m 1200.8889 379.5021 1946.5152 455.2626
B6.A-ChrX f 1036.6667 328.6585 1682.398 390.9354
B6.A-ChrX m 1573.6667 464.7933 2486.8686 660.4647
C57BL/6J f 1506.0182 153.5162 1807.6389 1204.3975
C57BL/6J m 1458.0189 156.3859 1765.2778 1150.7599


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both -394.85 261.5538 119.0374 -908.7374
B6.A-Chr1 both 595.8333 367.4513 1317.7829 -126.1162
B6.A-Chr10 both 1159.8726 212.5557 1577.4912 742.254
B6.A-Chr11 both 1750.8416 192.9649 2129.9692 1371.714
B6.A-Chr12 both 899.7735 176.4487 1246.4508 553.0962
B6.A-Chr14 both 760.7444 317.5143 1384.5801 136.9088
B6.A-Chr15 both 707.8038 239.4406 1178.2443 237.3633
B6.A-Chr16 both 1334.9316 246.8447 1819.9195 849.9438
B6.A-Chr17 both 1298.7222 379.5021 2044.3485 553.096
B6.A-Chr18 both 1664.0667 317.5143 2287.9024 1040.231
B6.A-Chr19 both 1649.75 254.5778 2149.9313 1149.5687
B6.A-Chr2 both 684.15 254.5778 1184.3313 183.9687
B6.A-Chr3 both 1820.2321 252.2945 2315.9274 1324.5369
B6.A-Chr4 both 1283.3167 261.5538 1797.2041 769.4292
B6.A-Chr5 both 1165.0071 235.6932 1628.085 701.9292
B6.A-Chr6 both 661.9111 261.5538 1175.7986 148.0237
B6.A-Chr7 both 648.9773 248.7246 1137.6586 160.2959
B6.A-Chr8 both 1393.8542 259.8273 1904.3496 883.3588
B6.A-Chr9 both 1388.5444 261.5538 1902.4319 874.657
B6.A-ChrX both 1305.1667 284.6266 1864.3864 745.947
C57BL/6J both 1482.0185 109.5716 1697.2992 1266.7378




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA