Project measure / variable:   Palmer2   activity_d1_OFT

ID, description, units MPD:30001   activity_d1_OFT   distance traveled   [cm]  control (day 1)  
methamphetamine study
Data set, strains Palmer2   B6.A consomic w/par   21 strains     sex: both     age: 7-16wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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Palmer2 - distance traveled control (day 1)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means5150   cm 5074   cm
Median of the strain means5381   cm 5451   cm
SD of the strain means± 1412 ± 1451
Coefficient of variation (CV)0.274 0.286
Min–max range of strain means775   –   7982   cm 997   –   7501   cm
Mean sample size per strain10.4   mice 11.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 11122841.0567 11122841.0567 6.2064 0.0131
strain 20 835396218.5546 41769810.9277 23.3071 < 0.0001
sex:strain 20 33875681.2437 1693784.0622 0.9451 0.5293
Residuals 497 890698173.312 1792149.2421


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 775.0 706.0   9 235.0 0.91 139.0, 1941.0 -3.1
A/J m 997.0 811.0   10 256.0 0.813 168.0, 2711.0 -2.81
B6.A-Chr1 f 3534.0 743.0   4 372.0 0.21 2625.0, 4441.0 -1.14
B6.A-Chr1 m 3745.0 288.0   6 117.0 0.0768 3500.0, 4183.0 -0.92
B6.A-Chr10 f 3771.0 1357.0   13 376.0 0.36 2272.0, 7227.0 -0.98
B6.A-Chr10 m 3441.0 865.0   16 216.0 0.251 2012.0, 4918.0 -1.13
B6.A-Chr11 f 6051.0 1238.0   14 331.0 0.205 4385.0, 8823.0 0.64
B6.A-Chr11 m 5451.0 1214.0   23 253.0 0.223 3561.0, 7527.0 0.26
B6.A-Chr12 f 3876.0 1200.0   15 310.0 0.31 1372.0, 5770.0 -0.9
B6.A-Chr12 m 3674.0 863.0   34 148.0 0.235 2067.0, 5358.0 -0.97
B6.A-Chr14 f 6162.0 602.0   9 201.0 0.0977 5179.0, 6901.0 0.72
B6.A-Chr14 m 6299.0 1629.0   5 729.0 0.259 4564.0, 8090.0 0.84
B6.A-Chr15 f 4860.0 934.0   10 295.0 0.192 3384.0, 5879.0 -0.21
B6.A-Chr15 m 3614.0 902.0   13 250.0 0.25 2384.0, 5225.0 -1.01
B6.A-Chr16 f 4247.0 1630.0   13 452.0 0.384 1856.0, 8464.0 -0.64
B6.A-Chr16 m 4176.0 946.0   9 315.0 0.227 3120.0, 6151.0 -0.62
B6.A-Chr17 f 5416.0 831.0   3 480.0 0.153 4555.0, 6214.0 0.19
B6.A-Chr17 m 6362.0 2027.0   9 676.0 0.319 3382.0, 9897.0 0.89
B6.A-Chr18 f 5381.0 829.0   5 371.0 0.154 4484.0, 6302.0 0.16
B6.A-Chr18 m 5730.0 1636.0   9 545.0 0.285 3548.0, 8657.0 0.45
B6.A-Chr19 f 5300.0 996.0   10 315.0 0.188 3129.0, 6861.0 0.11
B6.A-Chr19 m 5098.0 845.0   10 267.0 0.166 4005.0, 6806.0 0.02
B6.A-Chr2 f 5955.0 932.0   10 295.0 0.157 3701.0, 6832.0 0.57
B6.A-Chr2 m 5462.0 1314.0   10 415.0 0.241 2866.0, 6942.0 0.27
B6.A-Chr3 f 5690.0 2021.0   8 714.0 0.355 3629.0, 9874.0 0.38
B6.A-Chr3 m 4415.0 1534.0   14 410.0 0.347 1526.0, 6621.0 -0.45
B6.A-Chr4 f 5937.0 1626.0   10 514.0 0.274 3534.0, 8616.0 0.56
B6.A-Chr4 m 5862.0 971.0   9 324.0 0.166 4330.0, 7577.0 0.54
B6.A-Chr5 f 5950.0 1061.0   14 284.0 0.178 4560.0, 8293.0 0.57
B6.A-Chr5 m 5331.0 1232.0   10 390.0 0.231 3949.0, 7217.0 0.18
B6.A-Chr6 f 5086.0 1673.0   10 529.0 0.329 2933.0, 7421.0 -0.04
B6.A-Chr6 m 5143.0 1321.0   9 440.0 0.257 3171.0, 6952.0 0.05
B6.A-Chr7 f 6265.0 1321.0   10 418.0 0.211 3677.0, 8178.0 0.79
B6.A-Chr7 m 7009.0 2466.0   11 744.0 0.352 3362.0, 11298.0 1.33
B6.A-Chr8 f 5195.0 1094.0   12 316.0 0.211 3958.0, 7572.0 0.03
B6.A-Chr8 m 5626.0 1130.0   8 399.0 0.201 4059.0, 7593.0 0.38
B6.A-Chr9 f 7982.0 1729.0   10 547.0 0.217 5320.0, 10929.0 2.01
B6.A-Chr9 m 7501.0 1315.0   9 438.0 0.175 5550.0, 9605.0 1.67
B6.A-ChrX f 5052.0 1168.0   12 337.0 0.231 3557.0, 7320.0 -0.07
B6.A-ChrX m 6052.0 529.0   6 216.0 0.0875 5473.0, 6850.0 0.67
C57BL/6J f 5655.0 1474.0   55 199.0 0.261 2997.0, 9144.0 0.36
C57BL/6J m 5574.0 1699.0   53 233.0 0.305 1437.0, 10330.0 0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 775.2222 446.2373 1651.9663 0.0
A/J m 997.2 423.3378 1828.9524 165.4476
B6.A-Chr1 f 3534.25 669.3559 4849.3661 2219.1339
B6.A-Chr1 m 3745.3333 546.5268 4819.1211 2671.5456
B6.A-Chr10 f 3771.3077 371.2918 4500.8028 3041.8126
B6.A-Chr10 m 3440.6875 334.6779 4098.2455 2783.1295
B6.A-Chr11 f 6051.2143 357.7858 6754.1734 5348.2552
B6.A-Chr11 m 5451.2174 279.1407 5999.6587 4902.7761
B6.A-Chr12 f 3876.0 345.6539 4555.123 3196.877
B6.A-Chr12 m 3673.9412 229.5872 4125.0223 3222.8601
B6.A-Chr14 f 6161.5556 446.2373 7038.2996 5284.8115
B6.A-Chr14 m 6298.6 598.6901 7474.8756 5122.3244
B6.A-Chr15 f 4860.4 423.3378 5692.1524 4028.6476
B6.A-Chr15 m 3613.5385 371.2918 4343.0336 2884.0433
B6.A-Chr16 f 4246.8462 371.2918 4976.3413 3517.351
B6.A-Chr16 m 4175.7778 446.2373 5052.5218 3299.0337
B6.A-Chr17 f 5416.3333 772.9056 6934.8986 3897.7681
B6.A-Chr17 m 6361.8889 446.2373 7238.6329 5485.1448
B6.A-Chr18 f 5381.4 598.6901 6557.6756 4205.1244
B6.A-Chr18 m 5729.5556 446.2373 6606.2996 4852.8115
B6.A-Chr19 f 5300.3 423.3378 6132.0524 4468.5476
B6.A-Chr19 m 5098.3 423.3378 5930.0524 4266.5476
B6.A-Chr2 f 5955.4 423.3378 6787.1524 5123.6476
B6.A-Chr2 m 5462.1 423.3378 6293.8524 4630.3476
B6.A-Chr3 f 5690.0 473.3061 6619.9275 4760.0725
B6.A-Chr3 m 4414.5714 357.7858 5117.5305 3711.6123
B6.A-Chr4 f 5936.8 423.3378 6768.5524 5105.0476
B6.A-Chr4 m 5862.3333 446.2373 6739.0774 4985.5893
B6.A-Chr5 f 5949.5 357.7858 6652.4591 5246.5409
B6.A-Chr5 m 5331.0 423.3378 6162.7524 4499.2476
B6.A-Chr6 f 5085.6 423.3378 5917.3524 4253.8476
B6.A-Chr6 m 5143.2222 446.2373 6019.9663 4266.4782
B6.A-Chr7 f 6265.1 423.3378 7096.8524 5433.3476
B6.A-Chr7 m 7008.5455 403.6368 7801.5903 6215.5006
B6.A-Chr8 f 5195.25 386.4528 5954.5326 4435.9674
B6.A-Chr8 m 5625.5 473.3061 6555.4275 4695.5725
B6.A-Chr9 f 7981.5 423.3378 8813.2524 7149.7476
B6.A-Chr9 m 7500.7778 446.2373 8377.5218 6624.0337
B6.A-ChrX f 5052.1667 386.4528 5811.4493 4292.8841
B6.A-ChrX m 6051.5 546.5268 7125.2878 4977.7122
C57BL/6J f 5654.8182 180.5119 6009.4786 5300.1578
C57BL/6J m 5573.6981 183.8862 5934.9883 5212.4079


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 886.2111 307.5478 1490.4652 281.957
B6.A-Chr1 both 3639.7917 432.0674 4488.6954 2790.8879
B6.A-Chr10 both 3605.9976 249.9335 4097.054 3114.9412
B6.A-Chr11 both 5751.2158 226.8977 6197.0127 5305.419
B6.A-Chr12 both 3774.9706 207.477 4182.6108 3367.3304
B6.A-Chr14 both 6230.0778 373.3489 6963.6145 5496.5411
B6.A-Chr15 both 4236.9692 281.546 4790.1363 3683.8022
B6.A-Chr16 both 4211.312 290.2522 4781.5845 3641.0394
B6.A-Chr17 both 5889.1111 446.2373 6765.8552 5012.3671
B6.A-Chr18 both 5555.4778 373.3489 6289.0145 4821.9411
B6.A-Chr19 both 5199.3 299.3451 5787.4378 4611.1622
B6.A-Chr2 both 5708.75 299.3451 6296.8878 5120.6122
B6.A-Chr3 both 5052.2857 296.6603 5635.1486 4469.4228
B6.A-Chr4 both 5899.5667 307.5478 6503.8208 5295.3125
B6.A-Chr5 both 5640.25 277.1397 6184.7598 5095.7402
B6.A-Chr6 both 5114.4111 307.5478 5718.6652 4510.157
B6.A-Chr7 both 6636.8227 292.4626 7211.4383 6062.2072
B6.A-Chr8 both 5410.375 305.5178 6010.6406 4810.1094
B6.A-Chr9 both 7741.1389 307.5478 8345.393 7136.8848
B6.A-ChrX both 5551.8333 334.6779 6209.3914 4894.2753
C57BL/6J both 5614.2581 128.8397 5867.3958 5361.1205




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA