Phenotype measure

ID, description, units MPD:29514   Awave_area   calculated area under the A-wave mitral valve flow   [cm/s]
Data set, strains Eumorphia6   inbred   4 strains     sex: both     age: 12wks
Procedure echocardiography
Ontology mappings


  STRAIN COMPARISON PLOT
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Eumorphia6 - calculated area under the A-wave mitral valve flow



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means56.6   cm/s 55.0   cm/s
Median of the strain means57.7   cm/s 54.6   cm/s
SD of the strain means± 9.77 ± 6.27
Coefficient of variation (CV)0.172 0.114
Min–max range of strain means44.1   –   67.1   cm/s 48.1   –   62.8   cm/s
Mean sample size per strain5.8   mice 6.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 15.182 15.182 0.1389 0.7114
strain 3 2031.7244 677.2415 6.1957 0.0015
sex:strain 3 281.122 93.7073 0.8573 0.4713
Residuals 39 4262.9997 109.3077


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 44.1 7.18   6 2.93 0.163 36.2, 53.5 -1.28
129S2/SvPas m 48.1 8.45   6 3.45 0.176 35.3, 55.9 -1.11
BALB/cByJ f 60.6 20.5   6 8.38 0.339 33.8, 81.7 0.41
BALB/cByJ m 52.5 4.51   6 1.84 0.086 46.1, 58.3 -0.41
C3HeB/FeJ f 67.1 13.9   5 6.23 0.208 44.1, 81.0 1.07
C3HeB/FeJ m 62.8 7.49   6 3.06 0.119 53.7, 74.9 1.24
C57BL/6J f 54.7 6.18   6 2.52 0.113 45.9, 64.1 -0.2
C57BL/6J m 56.8 6.15   6 2.51 0.108 51.0, 64.4 0.28


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 44.1167 4.2682 52.75 35.4833
129S2/SvPas m 48.1167 4.2682 56.75 39.4833
BALB/cByJ f 60.6167 4.2682 69.25 51.9833
BALB/cByJ m 52.4833 4.2682 61.1167 43.85
C3HeB/FeJ f 67.12 4.6756 76.5774 57.6626
C3HeB/FeJ m 62.85 4.2682 71.4833 54.2167
C57BL/6J f 54.7167 4.2682 63.35 46.0833
C57BL/6J m 56.75 4.2682 65.3833 48.1167


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 46.1167 3.0181 52.2214 40.012
BALB/cByJ both 56.55 3.0181 62.6547 50.4453
C3HeB/FeJ both 64.985 3.1654 71.3877 58.5823
C57BL/6J both 55.7333 3.0181 61.838 49.6286