Project measure / variable:   Eumorphia6   Ewave_area

ID, description, units MPD:29513   Ewave_area   calculated area under the E-wave mitral valve flow   [cm/s]  
Data set, strains Eumorphia6   inbred   4 strains     sex: both     age: 12wks
Procedure echocardiography
Ontology mappings

  STRAIN COMPARISON PLOT
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Eumorphia6 - calculated area under the E-wave mitral valve flow



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means102   cm/s 103   cm/s
Median of the strain means100   cm/s 106   cm/s
SD of the strain means± 4.44 ± 9.67
Coefficient of variation (CV)0.0436 0.0942
Min–max range of strain means98.3   –   108   cm/s 88.3   –   109   cm/s
Mean sample size per strain5.8   mice 6.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 8.9511 8.9511 0.0629 0.8033
strain 3 1190.8312 396.9437 2.7882 0.0533
sex:strain 3 873.3278 291.1093 2.0448 0.1234
Residuals 39 5552.198 142.3641


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 98.3 17.5   6 7.15 0.178 68.3, 117.0 -0.79
129S2/SvPas m 105.0 9.29   6 3.79 0.0886 96.9, 120.0 0.25
BALB/cByJ f 108.0 8.99   6 3.67 0.0831 95.4, 116.0 1.4
BALB/cByJ m 109.0 6.05   6 2.47 0.0556 102.0, 118.0 0.66
C3HeB/FeJ f 102.0 15.1   5 6.77 0.149 78.0, 115.0 0.05
C3HeB/FeJ m 88.3 14.5   6 5.91 0.164 75.9, 116.0 -1.48
C57BL/6J f 98.9 9.09   6 3.71 0.0919 89.0, 115.0 -0.65
C57BL/6J m 108.0 11.1   6 4.55 0.103 98.6, 127.0 0.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 98.3167 4.8711 108.1693 88.464
129S2/SvPas m 104.9167 4.8711 114.7693 95.064
BALB/cByJ f 108.1667 4.8711 118.0193 98.314
BALB/cByJ m 108.8333 4.8711 118.686 98.9807
C3HeB/FeJ f 101.62 5.336 112.4131 90.8269
C3HeB/FeJ m 88.3 4.8711 98.1527 78.4473
C57BL/6J f 98.8667 4.8711 108.7193 89.014
C57BL/6J m 108.4333 4.8711 118.286 98.5807


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 101.6167 3.4444 108.5836 94.6498
BALB/cByJ both 108.5 3.4444 115.4669 101.5331
C3HeB/FeJ both 94.96 3.6125 102.2669 87.6531
C57BL/6J both 103.65 3.4444 110.6169 96.6831




GWAS analysis not available: SNP data is not available for enough strains (at least 4)