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Project measure / variable:   Eumorphia6   ejection_fraction

ID, description, units MPD:29508   ejection_fraction   cardiac ejection fraction   [%]  
Data set, strains Eumorphia6   inbred   4 strains     sex: both     age: 12wks
Procedure echocardiography
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  STRAIN COMPARISON PLOT
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Eumorphia6 - cardiac ejection fraction



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means68.8   % 66.6   %
Median of the strain means69.7   % 67.5   %
SD of the strain means± 3.66 ± 5.81
Coefficient of variation (CV)0.0531 0.0872
Min–max range of strain means63.7   –   72.3   % 59.9   –   71.7   %
Mean sample size per strain5.8   mice 6.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 67.3229 67.3229 1.9995 0.1653
strain 3 746.5771 248.859 7.3913 0.0005
sex:strain 3 83.974 27.9913 0.8314 0.4847
Residuals 39 1313.097 33.6692


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 70.1 3.63   6 1.48 0.0518 62.8, 72.6 0.35
129S2/SvPas m 71.3 6.8   6 2.77 0.0952 61.8, 81.2 0.8
BALB/cByJ f 72.3 6.92   6 2.82 0.0956 65.7, 83.4 0.95
BALB/cByJ m 71.7 6.36   6 2.6 0.0887 63.9, 80.8 0.87
C3HeB/FeJ f 63.7 7.48   5 3.35 0.118 56.1, 75.7 -1.4
C3HeB/FeJ m 59.9 6.45   6 2.63 0.108 53.2, 70.5 -1.16
C57BL/6J f 69.2 2.11   6 0.861 0.0304 67.1, 72.0 0.1
C57BL/6J m 63.7 4.91   6 2.0 0.0771 56.1, 70.4 -0.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 70.1 2.3689 74.8915 65.3085
129S2/SvPas m 71.35 2.3689 76.1415 66.5585
BALB/cByJ f 72.3333 2.3689 77.1248 67.5418
BALB/cByJ m 71.7333 2.3689 76.5248 66.9418
C3HeB/FeJ f 63.66 2.595 68.9088 58.4112
C3HeB/FeJ m 59.9 2.3689 64.6915 55.1085
C57BL/6J f 69.25 2.3689 74.0415 64.4585
C57BL/6J m 63.6833 2.3689 68.4748 58.8918


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 70.725 1.675 74.1131 67.3369
BALB/cByJ both 72.0333 1.675 75.4214 68.6452
C3HeB/FeJ both 61.78 1.7568 65.3335 58.2265
C57BL/6J both 66.4667 1.675 69.8548 63.0786




GWAS analysis not available: SNP data is not available for enough strains (at least 4)