Project measure / variable:   Eumorphia6   LVESD

ID, description, units MPD:29506   LVESD   left ventricle end-systolic diameter   [mm]  
Data set, strains Eumorphia6   inbred   4 strains     sex: both     age: 12wks
Procedure echocardiography
Ontology mappings

  STRAIN COMPARISON PLOT
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Eumorphia6 - left ventricle end-systolic diameter



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means2.51   mm 2.77   mm
Median of the strain means2.52   mm 2.71   mm
SD of the strain means± 0.278 ± 0.247
Coefficient of variation (CV)0.111 0.0891
Min–max range of strain means2.16   –   2.84   mm 2.56   –   3.11   mm
Mean sample size per strain5.8   mice 6.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.8784 0.8784 14.4312 0.0005
strain 3 2.1285 0.7095 11.6565 < 0.0001
sex:strain 3 0.219 0.073 1.1992 0.3228
Residuals 39 2.3738 0.0609


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 2.5 0.213   6 0.0871 0.0854 2.13, 2.77 -0.04
129S2/SvPas m 2.56 0.261   6 0.106 0.102 2.27, 2.91 -0.85
BALB/cByJ f 2.16 0.365   6 0.149 0.169 1.63, 2.7 -1.26
BALB/cByJ m 2.62 0.275   6 0.112 0.105 2.2, 2.98 -0.61
C3HeB/FeJ f 2.84 0.204   5 0.0913 0.0719 2.49, 2.98 1.19
C3HeB/FeJ m 3.11 0.21   6 0.0856 0.0674 2.7, 3.26 1.38
C57BL/6J f 2.54 0.199   6 0.0812 0.0783 2.2, 2.77 0.11
C57BL/6J m 2.79 0.189   6 0.077 0.0676 2.55, 2.98 0.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 2.4967 0.1007 2.7004 2.2929
129S2/SvPas m 2.565 0.1007 2.7687 2.3613
BALB/cByJ f 2.165 0.1007 2.3687 1.9613
BALB/cByJ m 2.615 0.1007 2.8187 2.4113
C3HeB/FeJ f 2.84 0.1103 3.0632 2.6168
C3HeB/FeJ m 3.1083 0.1007 3.3121 2.9046
C57BL/6J f 2.5417 0.1007 2.7454 2.3379
C57BL/6J m 2.7917 0.1007 2.9954 2.5879


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 2.5308 0.0712 2.6749 2.3868
BALB/cByJ both 2.39 0.0712 2.5341 2.2459
C3HeB/FeJ both 2.9742 0.0747 3.1253 2.8231
C57BL/6J both 2.6667 0.0712 2.8107 2.5226




GWAS analysis not available: SNP data is not available for enough strains (at least 4)