Project measure / variable:   Tomasini1   fibronectin

ID, description, units MPD:26101   fibronectin   fibronectin   [µg/mL]  
Data set, strains Tomasini1   inbred   25 strains     sex: both     age: 9wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Tomasini1 - fibronectin



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested24 strains24 strains
Mean of the strain means202   µg/mL 199   µg/mL
Median of the strain means192   µg/mL 182   µg/mL
SD of the strain means± 42.1 ± 65.7
Coefficient of variation (CV)0.208 0.331
Min–max range of strain means139   –   310   µg/mL 121   –   414   µg/mL
Mean sample size per strain7.8   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 111.5884 111.5884 0.0294 0.8639
strain 22 890934.1083 40497.0049 10.6811 < 0.0001
sex:strain 22 187702.2576 8531.9208 2.2503 0.0013
Residuals 317 1201896.1835 3791.4706


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 262.0 80.7   8 28.5 0.308 126.0, 363.0 1.42
129S1/SvImJ m 255.0 107.0   8 37.7 0.417 107.0, 409.0 0.86
A/J f 208.0 43.0   8 15.2 0.206 158.0, 274.0 0.14
A/J m 161.0 38.6   9 12.9 0.24 101.0, 220.0 -0.57
AKR/J f 166.0 35.3   8 12.5 0.213 119.0, 227.0 -0.86
AKR/J m 134.0 28.6   6 11.7 0.213 102.0, 185.0 -0.98
BALB/cByJ f 227.0 35.6   7 13.4 0.156 178.0, 273.0 0.59
BALB/cByJ m 352.0 197.0   8 69.7 0.56 149.0, 687.0 2.33
BALB/cJ f 176.0 65.1   8 23.0 0.371 85.0, 281.0 -0.62
BALB/cJ m 189.0 39.6   8 14.0 0.209 114.0, 232.0 -0.15
BTBR T+ Itpr3tf/J f 274.0 67.3   7 25.4 0.246 184.0, 373.0 1.71
BTBR T+ Itpr3tf/J m 230.0 124.0   8 43.8 0.538 101.0, 481.0 0.48
BUB/BnJ f 203.0 35.8   8 12.6 0.176 159.0, 255.0 0.02
BUB/BnJ m 166.0 34.4   8 12.2 0.207 112.0, 218.0 -0.5
C3H/HeJ f 157.0 40.4   8 14.3 0.258 93.0, 217.0 -1.07
C3H/HeJ m 176.0 72.2   9 24.1 0.411 111.0, 342.0 -0.34
C57BL/10J f 226.0 52.0   8 18.4 0.231 134.0, 294.0 0.57
C57BL/6J f 188.0 41.7   5 18.7 0.221 149.0, 259.0 -0.34
C57BL/6J m 140.0 16.9   7 6.39 0.121 110.0, 162.0 -0.89
C57L/J f 165.0 25.0   7 9.46 0.152 130.0, 198.0 -0.88
C57L/J m 162.0 33.4   8 11.8 0.206 122.0, 216.0 -0.56
C58/J f 209.0 47.6   8 16.8 0.228 148.0, 296.0 0.16
C58/J m 192.0 32.7   8 11.6 0.17 147.0, 250.0 -0.1
CAST/EiJ f 200.0 64.6   8 22.9 0.323 130.0, 284.0 -0.05
CAST/EiJ m 212.0 38.4   8 13.6 0.181 145.0, 257.0 0.2
DBA/2J f 191.0 32.4   8 11.4 0.17 128.0, 221.0 -0.27
DBA/2J m 196.0 35.4   9 11.8 0.181 126.0, 234.0 -0.04
FVB/NJ m 166.0 18.6   8 6.57 0.112 138.0, 189.0 -0.5
KK/HlJ f 205.0 23.1   8 8.18 0.113 181.0, 258.0 0.07
KK/HlJ m 159.0 31.1   8 11.0 0.195 120.0, 211.0 -0.6
LP/J f 190.0 57.9   13 16.1 0.305 116.0, 282.0 -0.29
LP/J m 209.0 84.5   8 29.9 0.404 107.0, 344.0 0.16
MOLF/EiJ f 194.0 22.2   6 9.07 0.115 160.0, 215.0 -0.19
MOLF/EiJ m 171.0 47.0   7 17.8 0.275 114.0, 238.0 -0.42
NZW/LacJ f 183.0 28.6   8 10.1 0.156 138.0, 216.0 -0.46
NZW/LacJ m 220.0 17.6   8 6.23 0.08 200.0, 252.0 0.32
PL/J f 186.0 54.0   10 17.1 0.291 136.0, 290.0 -0.38
PL/J m 220.0 43.9   7 16.6 0.2 172.0, 292.0 0.32
RIIIS/J f 270.0 88.0   7 33.3 0.326 182.0, 426.0 1.61
RIIIS/J m 197.0 59.9   9 20.0 0.304 111.0, 328.0 -0.03
SJL/J f 179.0 42.0   7 15.9 0.234 139.0, 258.0 -0.55
SJL/J m 161.0 57.6   8 20.4 0.358 112.0, 257.0 -0.57
SM/J f 139.0 43.6   8 15.4 0.314 92.0, 212.0 -1.5
SM/J m 165.0 22.7   8 8.01 0.138 139.0, 213.0 -0.51
SPRET/EiJ f 310.0 39.2   8 13.9 0.127 278.0, 390.0 2.56
SPRET/EiJ m 414.0 115.0   8 40.7 0.278 274.0, 627.0 3.28
SWR/J f 144.0 35.2   8 12.4 0.245 96.0, 208.0 -1.38
SWR/J m 121.0 45.8   7 17.3 0.377 88.0, 215.0 -1.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 261.75 21.77 304.582 218.918
129S1/SvImJ m 255.375 21.77 298.207 212.543
A/J f 208.5 21.77 251.332 165.668
A/J m 161.3333 20.525 201.7157 120.9509
AKR/J f 165.5 21.77 208.332 122.668
AKR/J m 134.3333 25.1379 183.7915 84.8752
BALB/cByJ f 227.2857 23.2731 273.075 181.4964
BALB/cByJ m 352.5 21.77 395.332 309.668
BALB/cJ f 175.625 21.77 218.457 132.793
BALB/cJ m 189.375 21.77 232.207 146.543
BTBR T+ Itpr3tf/J f 274.0 23.2731 319.7893 228.2107
BTBR T+ Itpr3tf/J m 230.125 21.77 272.957 187.293
BUB/BnJ f 202.875 21.77 245.707 160.043
BUB/BnJ m 166.375 21.77 209.207 123.543
C3H/HeJ f 156.875 21.77 199.707 114.043
C3H/HeJ m 175.6667 20.525 216.0491 135.2843
C57BL/6J f 188.4 27.5371 242.5787 134.2213
C57BL/6J m 139.7143 23.2731 185.5036 93.925
C57L/J f 164.7143 23.2731 210.5036 118.925
C57L/J m 162.5 21.77 205.332 119.668
C58/J f 208.625 21.77 251.457 165.793
C58/J m 191.875 21.77 234.707 149.043
CAST/EiJ f 199.875 21.77 242.707 157.043
CAST/EiJ m 211.625 21.77 254.457 168.793
DBA/2J f 190.625 21.77 233.457 147.793
DBA/2J m 195.6667 20.525 236.0491 155.2843
KK/HlJ f 204.875 21.77 247.707 162.043
KK/HlJ m 159.0 21.77 201.832 116.168
LP/J f 189.7692 17.0778 223.3694 156.1691
LP/J m 209.125 21.77 251.957 166.293
MOLF/EiJ f 193.6667 25.1379 243.1248 144.2085
MOLF/EiJ m 170.8571 23.2731 216.6465 125.0678
NZW/LacJ f 182.75 21.77 225.582 139.918
NZW/LacJ m 220.375 21.77 263.207 177.543
PL/J f 185.9 19.4717 224.2101 147.5899
PL/J m 219.7143 23.2731 265.5036 173.925
RIIIS/J f 269.7143 23.2731 315.5036 223.925
RIIIS/J m 196.7778 20.525 237.1602 156.3954
SJL/J f 179.4286 23.2731 225.2179 133.6393
SJL/J m 160.75 21.77 203.582 117.918
SM/J f 138.625 21.77 181.457 95.793
SM/J m 164.625 21.77 207.457 121.793
SPRET/EiJ f 309.625 21.77 352.457 266.793
SPRET/EiJ m 414.125 21.77 456.957 371.293
SWR/J f 143.5 21.77 186.332 100.668
SWR/J m 121.4286 23.2731 167.2179 75.6393


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 258.5625 15.3937 288.8493 228.2757
A/J both 184.9167 14.96 214.3501 155.4832
AKR/J both 149.9167 16.6271 182.6301 117.2032
BALB/cByJ both 289.8929 15.934 321.2427 258.5431
BALB/cJ both 182.5 15.3937 212.7868 152.2132
BTBR T+ Itpr3tf/J both 252.0625 15.934 283.4123 220.7127
BUB/BnJ both 184.625 15.3937 214.9118 154.3382
C3H/HeJ both 166.2708 14.96 195.7043 136.8374
C57BL/6J both 164.0571 18.0273 199.5254 128.5889
C57L/J both 163.6071 15.934 194.9569 132.2573
C58/J both 200.25 15.3937 230.5368 169.9632
CAST/EiJ both 205.75 15.3937 236.0368 175.4632
DBA/2J both 193.1458 14.96 222.5793 163.7124
KK/HlJ both 181.9375 15.3937 212.2243 151.6507
LP/J both 199.4471 13.8346 226.6664 172.2279
MOLF/EiJ both 182.2619 17.1286 215.9619 148.5619
NZW/LacJ both 201.5625 15.3937 231.8493 171.2757
PL/J both 202.8071 15.1722 232.6581 172.9562
RIIIS/J both 233.246 15.5154 263.7722 202.7198
SJL/J both 170.0893 15.934 201.4391 138.7395
SM/J both 151.625 15.3937 181.9118 121.3382
SPRET/EiJ both 361.875 15.3937 392.1618 331.5882
SWR/J both 132.4643 15.934 163.8141 101.1145




  GWAS USING LINEAR MIXED MODELS