Project measure / variable:   Palmer1   freezing_to_tones

ID, description, units MPD:25506   freezing_to_tones   average time freezing during two 30 s tones in altered context, day 3   [s]  
Data set, strains Palmer1   B6.A consomic w/par   19 strains     sex: both     age: 7-12wks
Procedure fear conditioning test
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  STRAIN COMPARISON PLOT
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Palmer1 - average time freezing during two 30 s tones in altered context, day 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested19 strains18 strains
Mean of the strain means51.9   s 47.9   s
Median of the strain means50.4   s 48.0   s
SD of the strain means± 10.0 ± 10.8
Coefficient of variation (CV)0.193 0.225
Min–max range of strain means34.8   –   72.7   s 32.9   –   75.0   s
Mean sample size per strain10.8   mice 11.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 733.3537 733.3537 2.2664 0.133
strain 17 37640.1218 2214.1248 6.8427 < 0.0001
sex:strain 17 4450.8299 261.8135 0.8091 0.6829
Residuals 415 134282.9012 323.5733


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 44.1 15.0   7 5.68 0.341 21.0, 67.0 -0.78
A/J m 45.4 19.5   9 6.51 0.43 7.14, 62.5 -0.23
B6.A-Chr1 f 50.4 22.4   8 7.92 0.444 17.4, 85.3 -0.15
B6.A-Chr1 m 49.4 13.9   11 4.19 0.282 30.8, 71.4 0.14
B6.A-Chr10 f 72.7 19.5   11 5.87 0.268 26.8, 95.1 2.08
B6.A-Chr10 m 75.0 9.92   14 2.65 0.132 48.2, 87.9 2.51
B6.A-Chr11 f 48.0 19.0   11 5.74 0.396 17.0, 85.6 -0.39
B6.A-Chr11 m 51.7 18.5   13 5.13 0.358 28.3, 89.2 0.35
B6.A-Chr12 f 34.8 18.2   12 5.26 0.523 3.58, 67.9 -1.71
B6.A-Chr12 m 32.9 15.2   9 5.06 0.462 13.8, 57.1 -1.39
B6.A-Chr14 f 47.0 15.3   11 4.61 0.326 22.8, 75.0 -0.49
B6.A-Chr14 m 41.8 23.7   11 7.14 0.567 2.68, 77.2 -0.57
B6.A-Chr15 f 68.1 20.7   7 7.83 0.304 33.9, 90.2 1.62
B6.A-Chr15 m 47.7 13.8   6 5.65 0.29 29.0, 64.7 -0.02
B6.A-Chr16 f 57.9 15.7   10 4.97 0.272 36.6, 90.2 0.6
B6.A-Chr17 f 48.0 19.6   12 5.67 0.409 16.5, 82.1 -0.39
B6.A-Chr17 m 51.2 14.1   11 4.24 0.275 29.0, 77.7 0.31
B6.A-Chr18 f 65.9 25.9   12 7.47 0.393 8.93, 92.4 1.4
B6.A-Chr18 m 69.8 17.2   11 5.19 0.247 40.6, 91.5 2.03
B6.A-Chr19 f 54.1 19.2   13 5.33 0.355 20.5, 79.0 0.22
B6.A-Chr19 m 49.4 18.7   12 5.4 0.379 23.7, 80.8 0.14
B6.A-Chr3 f 39.9 13.6   9 4.53 0.341 20.1, 58.0 -1.2
B6.A-Chr3 m 34.2 16.7   9 5.57 0.488 15.6, 65.6 -1.27
B6.A-Chr4 f 54.3 25.7   7 9.69 0.473 16.5, 80.8 0.24
B6.A-Chr4 m 48.4 16.0   11 4.81 0.33 18.8, 69.6 0.05
B6.A-Chr5 f 58.2 22.1   10 6.98 0.379 22.8, 92.0 0.63
B6.A-Chr5 m 35.6 9.94   13 2.76 0.279 21.4, 56.2 -1.14
B6.A-Chr6 f 60.0 22.3   9 7.43 0.372 13.8, 85.3 0.81
B6.A-Chr6 m 53.7 16.3   13 4.53 0.304 26.8, 76.3 0.54
B6.A-Chr7 f 42.6 16.8   13 4.67 0.395 20.9, 71.0 -0.93
B6.A-Chr7 m 42.3 16.6   13 4.6 0.393 12.1, 67.0 -0.52
B6.A-Chr9 f 44.3 20.7   14 5.52 0.466 10.3, 74.6 -0.76
B6.A-Chr9 m 44.1 14.9   12 4.29 0.337 19.6, 67.0 -0.35
B6.A-ChrX f 43.8 13.9   14 3.71 0.317 18.3, 74.1 -0.81
B6.A-ChrX m 41.1 15.4   11 4.64 0.374 8.48, 57.1 -0.63
C57BL/6J f 51.7 18.5   44 2.8 0.359 15.6, 87.1 -0.02
C57BL/6J m 48.6 18.4   38 2.99 0.38 17.9, 88.8 0.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 44.0857 6.7989 57.4502 30.7212
A/J m 45.4156 5.996 57.202 33.6291
B6.A-Chr1 f 50.45 6.3598 62.9514 37.9486
B6.A-Chr1 m 49.3545 5.4236 60.0158 38.6933
B6.A-Chr10 f 72.6909 5.4236 83.3521 62.0297
B6.A-Chr10 m 74.9714 4.8075 84.4216 65.5213
B6.A-Chr11 f 48.0182 5.4236 58.6794 37.357
B6.A-Chr11 m 51.6846 4.989 61.4915 41.8777
B6.A-Chr12 f 34.8317 5.1927 45.039 24.6243
B6.A-Chr12 m 32.8778 5.996 44.6642 21.0914
B6.A-Chr14 f 46.9545 5.4236 57.6158 36.2933
B6.A-Chr14 m 41.78 5.4236 52.4412 31.1188
B6.A-Chr15 f 68.1 6.7989 81.4645 54.7355
B6.A-Chr15 m 47.6833 7.3436 62.1187 33.248
B6.A-Chr17 f 47.9917 5.1927 58.199 37.7843
B6.A-Chr17 m 51.1727 5.4236 61.8339 40.5115
B6.A-Chr18 f 65.8942 5.1927 76.1015 55.6868
B6.A-Chr18 m 69.8 5.4236 80.4612 59.1388
B6.A-Chr19 f 54.1077 4.989 63.9146 44.3008
B6.A-Chr19 m 49.375 5.1927 59.5823 39.1677
B6.A-Chr3 f 39.8778 5.996 51.6642 28.0914
B6.A-Chr3 m 34.2333 5.996 46.0197 22.4469
B6.A-Chr4 f 54.2571 6.7989 67.6217 40.8926
B6.A-Chr4 m 48.4273 5.4236 59.0885 37.7661
B6.A-Chr5 f 58.22 5.6883 69.4016 47.0384
B6.A-Chr5 m 35.5769 4.989 45.3838 25.77
B6.A-Chr6 f 59.9556 5.996 71.742 48.1691
B6.A-Chr6 m 53.6692 4.989 63.4761 43.8623
B6.A-Chr7 f 42.5923 4.989 52.3992 32.7854
B6.A-Chr7 m 42.2615 4.989 52.0684 32.4547
B6.A-Chr9 f 44.2929 4.8075 53.743 34.8427
B6.A-Chr9 m 44.1167 5.1927 54.324 33.9093
B6.A-ChrX f 43.7786 4.8075 53.2287 34.3284
B6.A-ChrX m 41.1436 5.4236 51.8048 30.4824
C57BL/6J f 51.6545 2.7118 56.9852 46.3239
C57BL/6J m 48.5579 2.9181 54.2939 42.8219


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 44.7506 4.5326 53.6603 35.8409
B6.A-Chr1 both 49.9023 4.1792 58.1173 41.6873
B6.A-Chr10 both 73.8312 3.6238 80.9545 66.7078
B6.A-Chr11 both 49.8514 3.6846 57.0943 42.6085
B6.A-Chr12 both 33.8547 3.966 41.6507 26.0587
B6.A-Chr14 both 44.3673 3.8351 51.9059 36.8287
B6.A-Chr15 both 57.8917 5.0038 67.7277 48.0556
B6.A-Chr17 both 49.5822 3.7543 56.9621 42.2023
B6.A-Chr18 both 67.8471 3.7543 75.227 60.4672
B6.A-Chr19 both 51.7413 3.6005 58.8189 44.6638
B6.A-Chr3 both 37.0556 4.2398 45.3898 28.7213
B6.A-Chr4 both 51.3422 4.3486 59.8902 42.7942
B6.A-Chr5 both 46.8985 3.7831 54.3349 39.462
B6.A-Chr6 both 56.8124 3.9001 64.4788 49.146
B6.A-Chr7 both 42.4269 3.5278 49.3614 35.4924
B6.A-Chr9 both 44.2048 3.5382 51.1599 37.2496
B6.A-ChrX both 42.4611 3.6238 49.5844 35.3378
C57BL/6J both 50.1062 1.9918 54.0215 46.191




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA