Project measure / variable:   Palmer1   freezing_altered

ID, description, units MPD:25504   freezing_altered   time freezing in altered context (no tone) with 48h history and exposure to shock, from 30-180s, day 3   [s]  
Data set, strains Palmer1   B6.A consomic w/par   19 strains     sex: both     age: 7-12wks
Procedure fear conditioning test
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  STRAIN COMPARISON PLOT
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Palmer1 - time freezing in altered context (no tone) with 48h history and exposure to shock, from 30-180s, day 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested19 strains18 strains
Mean of the strain means16.0   s 15.2   s
Median of the strain means15.1   s 12.8   s
SD of the strain means± 7.41 ± 8.14
Coefficient of variation (CV)0.463 0.537
Min–max range of strain means8.70   –   42.0   s 6.17   –   40.6   s
Mean sample size per strain10.8   mice 11.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7.1807 7.1807 0.0577 0.8102
strain 17 17438.5722 1025.7984 8.2472 < 0.0001
sex:strain 17 2167.2685 127.4864 1.025 0.4293
Residuals 415 51618.377 124.3816


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 42.0 14.5   7 5.48 0.346 13.0, 56.4 3.51
A/J m 40.6 17.8   9 5.92 0.438 12.8, 66.2 3.13
B6.A-Chr1 f 18.6 10.0   8 3.54 0.537 6.94, 34.5 0.35
B6.A-Chr1 m 25.3 20.6   11 6.21 0.814 8.2, 82.0 1.25
B6.A-Chr10 f 18.3 11.9   11 3.59 0.652 1.07, 39.7 0.31
B6.A-Chr10 m 10.8 11.0   14 2.93 1.02 0.71, 43.6 -0.54
B6.A-Chr11 f 15.1 10.3   11 3.1 0.682 2.31, 36.9 -0.12
B6.A-Chr11 m 14.8 5.3   13 1.47 0.359 8.19, 22.4 -0.04
B6.A-Chr12 f 12.8 10.5   12 3.04 0.819 0.71, 37.1 -0.43
B6.A-Chr12 m 12.0 13.7   9 4.56 1.14 0.36, 40.8 -0.39
B6.A-Chr14 f 10.9 12.5   11 3.76 1.14 0.71, 37.0 -0.69
B6.A-Chr14 m 6.17 4.78   11 1.44 0.775 -1.1
B6.A-Chr15 f 12.2 5.85   7 2.21 0.48 3.74, 18.0 -0.51
B6.A-Chr15 m 9.58 10.1   6 4.12 1.05 1.07, 26.3 -0.69
B6.A-Chr16 f 17.0 16.2   10 5.13 0.955 1.42, 55.9 0.13
B6.A-Chr17 f 22.7 20.1   12 5.8 0.884 0.71, 65.3 0.9
B6.A-Chr17 m 13.7 11.7   11 3.54 0.856 1.6, 34.8 -0.18
B6.A-Chr18 f 9.44 8.39   12 2.42 0.889 -0.89
B6.A-Chr18 m 21.4 10.1   11 3.05 0.472 3.56, 36.2 0.77
B6.A-Chr19 f 8.92 7.3   13 2.02 0.818 1.78, 24.7 -0.96
B6.A-Chr19 m 10.3 8.11   12 2.34 0.785 1.96, 29.6 -0.6
B6.A-Chr3 f 8.7 8.53   9 2.84 0.98 -0.99
B6.A-Chr3 m 8.11 6.6   9 2.2 0.814 1.42, 24.6 -0.87
B6.A-Chr4 f 17.8 8.72   7 3.3 0.489 6.23, 27.9 0.24
B6.A-Chr4 m 18.8 22.0   11 6.62 1.17 1.6, 72.1 0.45
B6.A-Chr5 f 17.7 11.9   10 3.75 0.669 5.52, 39.3 0.23
B6.A-Chr5 m 17.6 12.2   13 3.39 0.695 1.07, 44.0 0.3
B6.A-Chr6 f 17.9 6.73   9 2.24 0.376 5.16, 23.7 0.26
B6.A-Chr6 m 19.1 12.1   13 3.35 0.632 6.41, 47.1 0.48
B6.A-Chr7 f 13.1 7.04   13 1.95 0.539 1.78, 20.6 -0.39
B6.A-Chr7 m 8.03 4.3   13 1.19 0.536 2.85, 17.6 -0.88
B6.A-Chr9 f 11.0 9.09   14 2.43 0.828 0.71, 25.4 -0.68
B6.A-Chr9 m 10.3 5.91   12 1.71 0.575 0.71, 19.4 -0.6
B6.A-ChrX f 17.3 12.3   14 3.3 0.714 2.31, 42.7 0.17
B6.A-ChrX m 14.5 11.7   11 3.54 0.809 0.71, 41.4 -0.08
C57BL/6J f 12.7 8.42   44 1.27 0.664 0.71, 39.9 -0.45
C57BL/6J m 11.8 10.7   38 1.74 0.905 -0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 41.9714 4.2153 50.2574 33.6854
A/J m 40.5556 3.7176 47.8631 33.248
B6.A-Chr1 f 18.63 3.9431 26.3809 10.8791
B6.A-Chr1 m 25.3 3.3627 31.91 18.69
B6.A-Chr10 f 18.2791 3.3627 24.889 11.6691
B6.A-Chr10 m 10.7657 2.9807 16.6248 4.9066
B6.A-Chr11 f 15.0864 3.3627 21.6963 8.4764
B6.A-Chr11 m 14.7638 3.0932 20.8441 8.6836
B6.A-Chr12 f 12.8483 3.2195 19.1769 6.5198
B6.A-Chr12 m 11.9844 3.7176 19.292 4.6769
B6.A-Chr14 f 10.9318 3.3627 17.5418 4.3219
B6.A-Chr14 m 6.1682 3.3627 12.7781 0.0
B6.A-Chr15 f 12.18 4.2153 20.466 3.894
B6.A-Chr15 m 9.585 4.5531 18.5349 0.6351
B6.A-Chr17 f 22.7375 3.2195 29.066 16.409
B6.A-Chr17 m 13.7218 3.3627 20.3318 7.1119
B6.A-Chr18 f 9.4375 3.2195 15.766 3.109
B6.A-Chr18 m 21.4145 3.3627 28.0245 14.8046
B6.A-Chr19 f 8.9246 3.0932 15.0049 2.8443
B6.A-Chr19 m 10.3392 3.2195 16.6677 4.0106
B6.A-Chr3 f 8.6978 3.7176 16.0054 1.3902
B6.A-Chr3 m 8.1144 3.7176 15.422 0.8069
B6.A-Chr4 f 17.8114 4.2153 26.0974 9.5254
B6.A-Chr4 m 18.7555 3.3627 25.3654 12.1455
B6.A-Chr5 f 17.736 3.5268 24.6686 10.8034
B6.A-Chr5 m 17.5838 3.0932 23.6641 11.5036
B6.A-Chr6 f 17.88 3.7176 25.1876 10.5724
B6.A-Chr6 m 19.0985 3.0932 25.1787 13.0182
B6.A-Chr7 f 13.0569 3.0932 19.1372 6.9767
B6.A-Chr7 m 8.0315 3.0932 14.1118 1.9513
B6.A-Chr9 f 10.99 2.9807 16.8491 5.1309
B6.A-Chr9 m 10.2867 3.2195 16.6152 3.9581
B6.A-ChrX f 17.2871 2.9807 23.1462 11.428
B6.A-ChrX m 14.5009 3.3627 21.1109 7.891
C57BL/6J f 12.6682 1.6813 15.9732 9.3632
C57BL/6J m 11.8424 1.8092 15.3987 8.286


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 41.2635 2.8102 46.7875 35.7395
B6.A-Chr1 both 21.965 2.5911 27.0583 16.8717
B6.A-Chr10 both 14.5224 2.2468 18.9389 10.1059
B6.A-Chr11 both 14.9251 2.2845 19.4157 10.4345
B6.A-Chr12 both 12.4164 2.4589 17.2499 7.5829
B6.A-Chr14 both 8.55 2.3778 13.2239 3.8761
B6.A-Chr15 both 10.8825 3.1024 16.9808 4.7842
B6.A-Chr17 both 18.2297 2.3277 22.8052 13.6541
B6.A-Chr18 both 15.426 2.3277 20.0016 10.8505
B6.A-Chr19 both 9.6319 2.2323 14.0199 5.2438
B6.A-Chr3 both 8.4061 2.6287 13.5733 3.2389
B6.A-Chr4 both 18.2834 2.6961 23.5832 12.9837
B6.A-Chr5 both 17.6599 2.3455 22.2705 13.0493
B6.A-Chr6 both 18.4892 2.4181 23.2424 13.7361
B6.A-Chr7 both 10.5442 2.1872 14.8436 6.2448
B6.A-Chr9 both 10.6383 2.1937 14.9505 6.3262
B6.A-ChrX both 15.894 2.2468 20.3105 11.4776
C57BL/6J both 12.2553 1.2349 14.6827 9.8278




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA