Project measure / variable:   Mills1   retic_micronucl_M12

ID, description, units MPD:25226   retic_micronucl_M12   reticulocytes with micronuclei   [%]  at age 12mo  
Data set, strains Mills1   inbred   30 strains     sex: both     age: 52wks
Procedure chromosome instability assessment
Ontology mappings

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  STRAIN COMPARISON PLOT
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Mills1 - reticulocytes with micronuclei at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains28 strains
Mean of the strain means0.0440   % 0.0394   %
Median of the strain means0.0248   % 0.0289   %
SD of the strain means± 0.0535 ± 0.0290
Coefficient of variation (CV)1.22 0.736
Min–max range of strain means0.00900   –   0.267   % 0.0103   –   0.120   %
Mean sample size per strain5.5   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.001 0.001 0.0908 0.7635
strain 23 0.3002 0.0131 1.2236 0.2273
sex:strain 23 0.2445 0.0106 0.9966 0.4712
Residuals 208 2.2187 0.0107


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0158 0.00449   6 0.00183 0.284 0.009, 0.021 -0.53
129S1/SvImJ m 0.0689 0.14   9 0.0465 2.03 0.012, 0.44 1.02
A/J m 0.063 0.0156   2   0.011 0.247 0.052, 0.074 0.81
AKR/J f 0.0183 0.00153   3 0.000882 0.0833 0.017, 0.02 -0.48
AKR/J m 0.0678 0.0797   5 0.0356 1.18 0.026, 0.21 0.98
BALB/cByJ f 0.046 0.0243   4 0.0122 0.529 0.029, 0.081 0.04
BALB/cByJ m 0.0367 0.00907   3 0.00524 0.247 0.027, 0.045 -0.09
BTBR T+ Itpr3tf/J f 0.0363 0.0592   7 0.0224 1.63 0.008, 0.17 -0.14
BTBR T+ Itpr3tf/J m 0.0308 0.0351   6 0.0143 1.14 0.008, 0.1 -0.3
BUB/BnJ f 0.0166 0.00798   7 0.00301 0.481 0.006, 0.028 -0.51
BUB/BnJ m 0.0265 0.00212   2   0.0015 0.08 0.025, 0.028 -0.45
C3H/HeJ m 0.0218 0.00823   5 0.00368 0.377 0.009, 0.032 -0.61
C57BL/10J m 0.0274 0.0108   5 0.00484 0.395 0.018, 0.045 -0.41
C57BL/6J f 0.025 0.0417   6 0.017 1.67 0.007, 0.11 -0.35
C57BL/6J m 0.018 0.00963   6 0.00393 0.535 0.01, 0.035 -0.74
C57BLKS/J f 0.015 0.0052   3 0.003 0.346 0.012, 0.021 -0.54
C57BLKS/J m 0.0148 0.00703   6 0.00287 0.474 0.007, 0.025 -0.85
C57BR/cdJ f 0.0209 0.00924   9 0.00308 0.442 0.008, 0.04 -0.43
C57BR/cdJ m 0.039 0.0204   4 0.0102 0.524 0.026, 0.069 -0.02
C57L/J f 0.0268 0.00342   5 0.00153 0.128 0.021, 0.03 -0.32
C57L/J m 0.0206 0.0147   5 0.00658 0.715 0.003, 0.037 -0.65
CBA/J f 0.0177 0.00622   6 0.00254 0.352 0.008, 0.026 -0.49
CBA/J m 0.022 0.00899   6 0.00367 0.409 0.013, 0.038 -0.6
DBA/2J f 0.009 0.00316   6 0.00129 0.351 0.005, 0.013 -0.65
DBA/2J m 0.0103 0.00321   3 0.00186 0.311 0.008, 0.014 -1.0
FVB/NJ f 0.123 0.0702   6 0.0287 0.569 0.065, 0.25 1.48
FVB/NJ m 0.0178 0.00661   5 0.00296 0.371 0.009, 0.027 -0.75
KK/HlJ f 0.0295 0.013   6 0.00531 0.441 0.018, 0.05 -0.27
KK/HlJ m 0.0407 0.0115   7 0.00434 0.282 0.027, 0.052 0.04
LP/J f 0.0198 0.00817   5 0.00365 0.412 0.01, 0.029 -0.45
LP/J m 0.0203 0.00651   3 0.00376 0.32 0.014, 0.027 -0.66
MRL/MpJ f 0.267 0.59   6 0.241 2.21 0.015, 1.47 4.17
MRL/MpJ m 0.032 0.0191   5 0.00856 0.598 0.013, 0.061 -0.26
NOD.B10Sn-H2b/J f 0.0565 0.05   4 0.025 0.885 0.025, 0.13 0.23
NOD.B10Sn-H2b/J m 0.023 0.00608   3 0.00351 0.264 0.016, 0.027 -0.57
NON/ShiLtJ f 0.0914 0.136   9 0.0453 1.49 0.018, 0.44 0.89
NON/ShiLtJ m 0.0935 0.0347   8 0.0123 0.371 0.042, 0.15 1.86
NZO/HlLtJ f 0.018 0.0099   2   0.007 0.55 0.011, 0.025 -0.49
NZO/HlLtJ m 0.101 0.0738   4 0.0369 0.731 0.053, 0.21 2.12
NZW/LacJ f 0.0245 0.0106   4 0.00532 0.434 0.009, 0.033 -0.36
NZW/LacJ m 0.12 0.0569   6 0.0232 0.474 0.069, 0.22 2.78
P/J m 0.0304 0.0222   5 0.00991 0.729 0.013, 0.061 -0.31
PL/J f 0.091 0.0774   5 0.0346 0.851 0.031, 0.22 0.88
PL/J m 0.0326 0.00829   5 0.00371 0.254 0.022, 0.045 -0.24
PWD/PhJ f 0.0303 0.0174   6 0.0071 0.574 0.008, 0.048 -0.26
PWD/PhJ m 0.0154 0.00532   5 0.00238 0.345 0.01, 0.023 -0.83
RIIIS/J f 0.0193 0.00784   6 0.0032 0.406 0.008, 0.027 -0.46
RIIIS/J m 0.015 0.00481   8 0.0017 0.321 0.009, 0.022 -0.84
SJL/J f 0.0347 0.00812   6 0.00331 0.234 0.025, 0.045 -0.17
SM/J f 0.0167 0.0107   6 0.00437 0.642 0.009, 0.038 -0.51
SM/J m 0.0743 0.0432   3 0.025 0.582 0.034, 0.12 1.2
SWR/J f 0.062 0.0226   5 0.0101 0.365 0.034, 0.086 0.34
WSB/EiJ f 0.012 0.00932   6 0.0038 0.776 0.002, 0.027 -0.6
WSB/EiJ m 0.0207 0.0128   6 0.00524 0.621 0.004, 0.038 -0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0158 0.0422 0.099 0.0
129S1/SvImJ m 0.0689 0.0344 0.1368 0.001
AKR/J f 0.0183 0.0596 0.1359 0.0
AKR/J m 0.0678 0.0462 0.1589 0.0
BALB/cByJ f 0.046 0.0516 0.1478 0.0
BALB/cByJ m 0.0367 0.0596 0.1542 0.0
BTBR T+ Itpr3tf/J f 0.0363 0.039 0.1132 0.0
BTBR T+ Itpr3tf/J m 0.0308 0.0422 0.114 0.0
BUB/BnJ f 0.0166 0.039 0.0935 0.0
BUB/BnJ m 0.0265 0.073 0.1705 0.0
C57BL/6J f 0.025 0.0422 0.1081 0.0
C57BL/6J m 0.018 0.0422 0.1011 0.0
C57BLKS/J f 0.015 0.0596 0.1326 0.0
C57BLKS/J m 0.0148 0.0422 0.098 0.0
C57BR/cdJ f 0.0209 0.0344 0.0888 0.0
C57BR/cdJ m 0.039 0.0516 0.1408 0.0
C57L/J f 0.0268 0.0462 0.1179 0.0
C57L/J m 0.0206 0.0462 0.1117 0.0
CBA/J f 0.0177 0.0422 0.1008 0.0
CBA/J m 0.022 0.0422 0.1051 0.0
DBA/2J f 0.009 0.0422 0.0921 0.0
DBA/2J m 0.0103 0.0596 0.1279 0.0
FVB/NJ f 0.1235 0.0422 0.2066 0.0404
FVB/NJ m 0.0178 0.0462 0.1089 0.0
KK/HlJ f 0.0295 0.0422 0.1126 0.0
KK/HlJ m 0.0407 0.039 0.1177 0.0
LP/J f 0.0198 0.0462 0.1109 0.0
LP/J m 0.0203 0.0596 0.1379 0.0
MRL/MpJ f 0.2668 0.0422 0.35 0.1837
MRL/MpJ m 0.032 0.0462 0.1231 0.0
NOD.B10Sn-H2b/J f 0.0565 0.0516 0.1583 0.0
NOD.B10Sn-H2b/J m 0.023 0.0596 0.1406 0.0
NON/ShiLtJ f 0.0914 0.0344 0.1593 0.0236
NON/ShiLtJ m 0.0935 0.0365 0.1655 0.0215
NZO/HlLtJ f 0.018 0.073 0.162 0.0
NZO/HlLtJ m 0.101 0.0516 0.2028 0.0
NZW/LacJ f 0.0245 0.0516 0.1263 0.0
NZW/LacJ m 0.12 0.0422 0.2031 0.0369
PL/J f 0.091 0.0462 0.1821 0.0
PL/J m 0.0326 0.0462 0.1237 0.0
PWD/PhJ f 0.0303 0.0422 0.1135 0.0
PWD/PhJ m 0.0154 0.0462 0.1065 0.0
RIIIS/J f 0.0193 0.0422 0.1025 0.0
RIIIS/J m 0.015 0.0365 0.087 0.0
SM/J f 0.0167 0.0422 0.0998 0.0
SM/J m 0.0743 0.0596 0.1919 0.0
WSB/EiJ f 0.012 0.0422 0.0951 0.0
WSB/EiJ m 0.0207 0.0422 0.1038 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0424 0.0272 0.096 0.0
AKR/J both 0.0431 0.0377 0.1174 0.0
BALB/cByJ both 0.0413 0.0394 0.1191 0.0
BTBR T+ Itpr3tf/J both 0.0336 0.0287 0.0902 0.0
BUB/BnJ both 0.0215 0.0414 0.1032 0.0
C57BL/6J both 0.0215 0.0298 0.0803 0.0
C57BLKS/J both 0.0149 0.0365 0.0869 0.0
C57BR/cdJ both 0.0299 0.031 0.0911 0.0
C57L/J both 0.0237 0.0327 0.0881 0.0
CBA/J both 0.0198 0.0298 0.0786 0.0
DBA/2J both 0.0097 0.0365 0.0817 0.0
FVB/NJ both 0.0707 0.0313 0.1323 0.009
KK/HlJ both 0.0351 0.0287 0.0917 0.0
LP/J both 0.0201 0.0377 0.0944 0.0
MRL/MpJ both 0.1494 0.0313 0.2111 0.0878
NOD.B10Sn-H2b/J both 0.0398 0.0394 0.1175 0.0
NON/ShiLtJ both 0.0925 0.0251 0.1419 0.043
NZO/HlLtJ both 0.0595 0.0447 0.1477 0.0
NZW/LacJ both 0.0723 0.0333 0.138 0.0065
PL/J both 0.0618 0.0327 0.1262 0.0
PWD/PhJ both 0.0229 0.0313 0.0845 0.0
RIIIS/J both 0.0172 0.0279 0.0721 0.0
SM/J both 0.0455 0.0365 0.1175 0.0
WSB/EiJ both 0.0163 0.0298 0.0751 0.0




  GWAS USING LINEAR MIXED MODELS