Project measure / variable:   Mills1   retic_micronucl_M06

ID, description, units MPD:25225   retic_micronucl_M06   reticulocytes with micronuclei   [%]  at age 6mo  
Data set, strains Mills1   inbred   7 strains     sex: both     age: 26wks
Procedure chromosome instability assessment
Ontology mappings

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  STRAIN COMPARISON PLOT
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Mills1 - reticulocytes with micronuclei at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains7 strains
Mean of the strain means0.0323   % 0.0465   %
Median of the strain means0.0332   % 0.0298   %
SD of the strain means± 0.00995 ± 0.0474
Coefficient of variation (CV)0.308 1.02
Min–max range of strain means0.0168   –   0.0432   % 0.0187   –   0.152   %
Mean sample size per strain5.6   mice 5.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0005 0.0005 0.4268 0.5171
strain 4 0.0128 0.0032 2.9143 0.0325
sex:strain 4 0.0331 0.0083 7.5294 0.0001
Residuals 42 0.0461 0.0011


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J m 0.0425 0.0141   6 0.00577 0.333 0.025, 0.065 -0.08
AKR/J f 0.038 0.0138   6 0.00562 0.362 0.02, 0.06 0.57
AKR/J m 0.0227 0.00619   6 0.00253 0.273 0.014, 0.031 -0.5
BALB/cByJ f 0.0432 0.016   6 0.00654 0.371 0.018, 0.067 1.09
BALB/cByJ m 0.0213 0.0133   6 0.00542 0.622 0.009, 0.045 -0.53
C57BL/6J m 0.0298 0.0087   6 0.00355 0.292 0.021, 0.046 -0.35
KK/HlJ f 0.0332 0.0157   6 0.00642 0.474 0.019, 0.06 0.09
KK/HlJ m 0.0383 0.0175   3 0.0101 0.456 0.019, 0.053 -0.17
NZO/HlLtJ f 0.0168 0.00858   4 0.00429 0.512 0.009, 0.029 -1.56
NZO/HlLtJ m 0.152 0.138   3 0.0794 0.907 0.015, 0.29 2.23
SM/J f 0.0303 0.0114   6 0.00467 0.377 0.02, 0.051 -0.2
SM/J m 0.0187 0.0215   6 0.00876 1.15 0.006, 0.061 -0.59


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
AKR/J f 0.038 0.0135 0.0653 0.0107
AKR/J m 0.0227 0.0135 0.05 0.0
BALB/cByJ f 0.0432 0.0135 0.0705 0.0159
BALB/cByJ m 0.0213 0.0135 0.0486 0.0
KK/HlJ f 0.0332 0.0135 0.0605 0.0059
KK/HlJ m 0.0383 0.0191 0.077 0.0
NZO/HlLtJ f 0.0167 0.0166 0.0502 0.0
NZO/HlLtJ m 0.1517 0.0191 0.1903 0.113
SM/J f 0.0303 0.0135 0.0576 0.003
SM/J m 0.0187 0.0135 0.046 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
AKR/J both 0.0303 0.0096 0.0496 0.011
BALB/cByJ both 0.0323 0.0096 0.0516 0.0129
KK/HlJ both 0.0357 0.0117 0.0594 0.0121
NZO/HlLtJ both 0.0842 0.0127 0.1098 0.0587
SM/J both 0.0245 0.0096 0.0438 0.0052




  GWAS USING LINEAR MIXED MODELS