Project measure / variable:   Mills1   all_apoptotic_M20

ID, description, units MPD:25219   all_apoptotic_M20   all apoptotic splenocytes   [%]  at age 20mo  
Data set, strains Mills1   inbred   28 strains     sex: both     age: 87wks
Procedure apoptosis assessment
Ontology mappings

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  STRAIN COMPARISON PLOT
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Mills1 - all apoptotic splenocytes at age 20mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains28 strains
Mean of the strain means9.76   % 8.84   %
Median of the strain means9.62   % 8.41   %
SD of the strain means± 2.65 ± 2.88
Coefficient of variation (CV)0.272 0.325
Min–max range of strain means5.53   –   15.1   % 5.70   –   18.4   %
Mean sample size per strain3.2   mice 2.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9.6712 9.6712 1.2206 0.272
strain 22 512.9149 23.3143 2.9424 0.0001
sex:strain 22 428.5505 19.4796 2.4585 0.0014
Residuals 96 760.653 7.9235


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.6 0.929   3 0.536 0.0874 10.0, 11.7 0.32
129S1/SvImJ m 8.53 2.67   3 1.54 0.313 6.7, 11.6 -0.11
A/J f 8.1 0.515   5 0.23 0.0636 7.3, 8.6 -0.63
A/J m 7.23 0.231   3 0.133 0.0319 7.1, 7.5 -0.56
BALB/cByJ f 6.26 3.35   5 1.5 0.536 3.8, 11.8 -1.32
BALB/cByJ m 9.22 0.829   5 0.371 0.0899 8.3, 10.1 0.13
BTBR T+ Itpr3tf/J f 9.43 0.404   3 0.233 0.0428 9.2, 9.9 -0.13
BTBR T+ Itpr3tf/J m 10.2 0.212   2   0.15 0.0207 10.1, 10.4 0.47
BUB/BnJ f 8.17 0.379   3 0.219 0.0464 7.9, 8.6 -0.6
BUB/BnJ m 6.6 0.99   2   0.7 0.15 5.9, 7.3 -0.78
C3H/HeJ f 8.43 0.513   3 0.296 0.0608 8.0, 9.0 -0.5
C3H/HeJ m 8.8 0.361   3 0.208 0.041 8.4, 9.1 -0.01
C57BL/10J f 12.2 2.1   3 1.21 0.173 10.0, 14.2 0.92
C57BL/10J m 7.43 0.231   3 0.133 0.0311 7.3, 7.7 -0.49
C57BL/6J f 10.5 1.01   3 0.581 0.0962 9.4, 11.4 0.28
C57BL/6J m 5.97 0.874   3 0.504 0.146 5.0, 6.7 -1.0
C57BLKS/J f 5.53 0.945   3 0.546 0.171 4.8, 6.6 -1.6
C57BLKS/J m 5.7 0.265   3 0.153 0.0464 5.4, 5.9 -1.09
C57BR/cdJ f 7.4 1.51   3 0.872 0.204 5.8, 8.8 -0.89
C57BR/cdJ m 8.3 3.52   3 2.03 0.424 5.7, 12.3 -0.19
C57L/J f 8.33 2.28   3 1.32 0.274 6.3, 10.8 -0.54
C57L/J m 12.7 3.3   3 1.91 0.26 10.5, 16.5 1.34
CBA/J f 12.7 1.67   3 0.967 0.132 11.7, 14.6 1.11
CBA/J m 5.85 0.212   2   0.15 0.0363 5.7, 6.0 -1.04
DBA/2J f 9.73 1.29   3 0.745 0.133 8.3, 10.8 -0.01
DBA/2J m 9.33 1.24   3 0.717 0.133 7.9, 10.1 0.17
FVB/NJ f 5.57 0.321   3 0.186 0.0577 5.2, 5.8 -1.58
FVB/NJ m 11.1 1.9   3 1.1 0.171 9.2, 13.0 0.78
KK/HlJ f 9.5 2.3   5 1.03 0.242 6.7, 12.8 -0.1
KK/HlJ m 10.9 2.36   3 1.36 0.216 9.1, 13.6 0.72
LP/J f 13.6 7.93   3 4.58 0.584 8.5, 22.7 1.45
LP/J m 7.27 0.416   3 0.24 0.0573 6.8, 7.6 -0.55
MRL/MpJ f 7.0 0.0   1   0.0 0.0 7.0, 7.0 -1.04
MRL/MpJ m 8.97 3.02   3 1.74 0.336 5.5, 11.0 0.04
NOD.B10Sn-H2b/J f 9.9 3.29   3 1.9 0.332 6.2, 12.5 0.05
NOD.B10Sn-H2b/J m 6.3 0.424   2   0.3 0.0673 6.0, 6.6 -0.88
NON/ShiLtJ f 11.9 2.51   3 1.45 0.21 9.8, 14.7 0.81
NON/ShiLtJ m 14.0 7.07   2   5.0 0.505 9.0, 19.0 1.79
NZO/HlLtJ f 15.1 7.99   2   5.65 0.531 9.4, 20.7 2.01
NZO/HlLtJ m 11.2 2.05   2   1.45 0.182 9.8, 12.7 0.82
NZW/LacJ f 14.5 8.44   3 4.87 0.581 8.6, 24.2 1.79
NZW/LacJ m 10.4 1.82   3 1.05 0.175 9.2, 12.5 0.54
P/J f 8.53 0.153   3 0.0882 0.0179 8.4, 8.7 -0.47
P/J m 9.5 0.0   1   0.0 0.0 9.5, 9.5 0.23
PL/J f 13.2 8.52   3 4.92 0.647 8.1, 23.0 1.3
PL/J m 6.5 0.0   1   0.0 0.0 6.5, 6.5 -0.81
PWD/PhJ f 9.8 2.86   3 1.65 0.292 8.0, 13.1 0.01
PWD/PhJ m 8.1 0.787   5 0.352 0.0972 7.3, 9.3 -0.26
RIIIS/J f 7.38 1.18   5 0.527 0.16 5.9, 8.6 -0.9
RIIIS/J m 6.57 0.153   3 0.0882 0.0233 6.4, 6.7 -0.79
SM/J f 10.5 1.07   3 0.617 0.102 9.8, 11.7 0.28
SM/J m 18.4 10.5   2   7.45 0.571 11.0, 25.9 3.32
SWR/J m 6.0 1.39   3 0.802 0.232 5.1, 7.6 -0.99
WSB/EiJ m 6.53 0.635   3 0.367 0.0972 5.8, 6.9 -0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.6333 1.6252 13.8593 7.4074
129S1/SvImJ m 8.5333 1.6252 11.7593 5.3074
A/J f 8.1 1.2588 10.5988 5.6012
A/J m 7.2333 1.6252 10.4593 4.0074
BALB/cByJ f 6.26 1.2588 8.7588 3.7612
BALB/cByJ m 9.22 1.2588 11.7188 6.7212
BTBR T+ Itpr3tf/J f 9.4333 1.6252 12.6593 6.2074
BTBR T+ Itpr3tf/J m 10.25 1.9904 14.2009 6.2991
BUB/BnJ f 8.1667 1.6252 11.3926 4.9407
BUB/BnJ m 6.6 1.9904 10.5509 2.6491
C3H/HeJ f 8.4333 1.6252 11.6593 5.2074
C3H/HeJ m 8.8 1.6252 12.0259 5.5741
C57BL/10J f 12.1667 1.6252 15.3926 8.9407
C57BL/10J m 7.4333 1.6252 10.6593 4.2074
C57BL/6J f 10.4667 1.6252 13.6926 7.2407
C57BL/6J m 5.9667 1.6252 9.1926 2.7407
C57BLKS/J f 5.5333 1.6252 8.7593 2.3074
C57BLKS/J m 5.7 1.6252 8.9259 2.4741
C57BR/cdJ f 7.4 1.6252 10.6259 4.1741
C57BR/cdJ m 8.3 1.6252 11.5259 5.0741
C57L/J f 8.3333 1.6252 11.5593 5.1074
C57L/J m 12.7 1.6252 15.9259 9.4741
CBA/J f 12.6667 1.6252 15.8926 9.4407
CBA/J m 5.85 1.9904 9.8009 1.8991
DBA/2J f 9.7333 1.6252 12.9593 6.5074
DBA/2J m 9.3333 1.6252 12.5593 6.1074
FVB/NJ f 5.5667 1.6252 8.7926 2.3407
FVB/NJ m 11.1333 1.6252 14.3593 7.9074
KK/HlJ f 9.5 1.2588 11.9988 7.0012
KK/HlJ m 10.9333 1.6252 14.1593 7.7074
LP/J f 13.5667 1.6252 16.7926 10.3407
LP/J m 7.2667 1.6252 10.4926 4.0407
NOD.B10Sn-H2b/J f 9.9 1.6252 13.1259 6.6741
NOD.B10Sn-H2b/J m 6.3 1.9904 10.2509 2.3491
NON/ShiLtJ f 11.9333 1.6252 15.1593 8.7074
NON/ShiLtJ m 14.0 1.9904 17.9509 10.0491
NZO/HlLtJ f 15.05 1.9904 19.0009 11.0991
NZO/HlLtJ m 11.25 1.9904 15.2009 7.2991
NZW/LacJ f 14.5333 1.6252 17.7593 11.3074
NZW/LacJ m 10.4 1.6252 13.6259 7.1741
PWD/PhJ f 9.8 1.6252 13.0259 6.5741
PWD/PhJ m 8.1 1.2588 10.5988 5.6012
RIIIS/J f 7.38 1.2588 9.8788 4.8812
RIIIS/J m 6.5667 1.6252 9.7926 3.3407
SM/J f 10.4667 1.6252 13.6926 7.2407
SM/J m 18.45 1.9904 22.4009 14.4991


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 9.5833 1.1492 11.8644 7.3023
A/J both 7.6667 1.0278 9.7069 5.6264
BALB/cByJ both 7.74 0.8901 9.5069 5.9731
BTBR T+ Itpr3tf/J both 9.8417 1.2848 12.392 7.2913
BUB/BnJ both 7.3833 1.2848 9.9337 4.833
C3H/HeJ both 8.6167 1.1492 10.8977 6.3356
C57BL/10J both 9.8 1.1492 12.0811 7.5189
C57BL/6J both 8.2167 1.1492 10.4977 5.9356
C57BLKS/J both 5.6167 1.1492 7.8977 3.3356
C57BR/cdJ both 7.85 1.1492 10.1311 5.5689
C57L/J both 10.5167 1.1492 12.7977 8.2356
CBA/J both 9.2583 1.2848 11.8087 6.708
DBA/2J both 9.5333 1.1492 11.8144 7.2523
FVB/NJ both 8.35 1.1492 10.6311 6.0689
KK/HlJ both 10.2167 1.0278 12.2569 8.1764
LP/J both 10.4167 1.1492 12.6977 8.1356
NOD.B10Sn-H2b/J both 8.1 1.2848 10.6503 5.5497
NON/ShiLtJ both 12.9667 1.2848 15.517 10.4163
NZO/HlLtJ both 13.15 1.4074 15.9437 10.3563
NZW/LacJ both 12.4667 1.1492 14.7477 10.1856
PWD/PhJ both 8.95 1.0278 10.9903 6.9097
RIIIS/J both 6.9733 1.0278 9.0136 4.9331
SM/J both 14.4583 1.2848 17.0087 11.908




  GWAS USING LINEAR MIXED MODELS