Project measure / variable:   Mills1   late_apoptotic_M20

ID, description, units MPD:25213   late_apoptotic_M20   late apoptotic splenocytes   [%]  at age 20mo  
Data set, strains Mills1   inbred   28 strains     sex: both     age: 87wks
Procedure apoptosis assessment
Ontology mappings

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  STRAIN COMPARISON PLOT
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Mills1 - late apoptotic splenocytes at age 20mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains28 strains
Mean of the strain means4.89   % 5.14   %
Median of the strain means5.00   % 4.73   %
SD of the strain means± 1.08 ± 1.48
Coefficient of variation (CV)0.220 0.287
Min–max range of strain means2.87   –   6.77   % 3.40   –   9.05   %
Mean sample size per strain3.2   mice 2.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6.8422 6.8422 4.4908 0.0367
strain 22 132.7753 6.0352 3.9611 < 0.0001
sex:strain 22 86.4908 3.9314 2.5803 0.0008
Residuals 96 146.2667 1.5236


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.1 0.52   3 0.3 0.102 4.5, 5.4 0.19
129S1/SvImJ m 5.1 1.21   3 0.7 0.238 4.4, 6.5 -0.03
A/J f 3.86 0.841   5 0.376 0.218 2.9, 5.1 -0.96
A/J m 4.9 0.794   3 0.458 0.162 4.0, 5.5 -0.17
BALB/cByJ f 3.86 1.86   5 0.83 0.481 1.9, 6.6 -0.96
BALB/cByJ m 6.92 0.864   5 0.387 0.125 6.2, 8.4 1.2
BTBR T+ Itpr3tf/J f 4.57 0.777   3 0.448 0.17 3.7, 5.2 -0.3
BTBR T+ Itpr3tf/J m 5.85 0.212   2   0.15 0.0363 5.7, 6.0 0.48
BUB/BnJ f 3.9 0.3   3 0.173 0.0769 3.6, 4.2 -0.92
BUB/BnJ m 4.2 0.0   2   0.0 0.0 4.2, 4.2 -0.64
C3H/HeJ f 5.5 1.21   3 0.7 0.22 4.8, 6.9 0.56
C3H/HeJ m 4.7 0.529   3 0.306 0.113 4.1, 5.1 -0.3
C57BL/10J f 6.33 0.252   3 0.145 0.0397 6.1, 6.6 1.33
C57BL/10J m 3.87 1.16   3 0.669 0.3 3.1, 5.2 -0.86
C57BL/6J f 5.1 1.35   3 0.781 0.265 3.7, 6.4 0.19
C57BL/6J m 3.73 0.473   3 0.273 0.127 3.2, 4.1 -0.96
C57BLKS/J f 2.87 0.115   3 0.0667 0.0403 2.8, 3.0 -1.88
C57BLKS/J m 3.9 0.608   3 0.351 0.156 3.2, 4.3 -0.84
C57BR/cdJ f 3.47 1.87   3 1.08 0.54 2.1, 5.6 -1.32
C57BR/cdJ m 3.93 0.85   3 0.491 0.216 3.3, 4.9 -0.82
C57L/J f 5.1 1.13   3 0.651 0.221 3.8, 5.8 0.19
C57L/J m 6.97 0.808   3 0.467 0.116 6.1, 7.7 1.24
CBA/J f 4.0 0.265   3 0.153 0.0661 3.8, 4.3 -0.83
CBA/J m 4.4 0.0   2   0.0 0.0 4.4, 4.4 -0.5
DBA/2J f 6.43 1.03   3 0.593 0.16 5.3, 7.3 1.43
DBA/2J m 5.6 1.95   3 1.13 0.349 3.7, 7.6 0.31
FVB/NJ f 3.47 0.115   3 0.0667 0.0333 3.4, 3.6 -1.32
FVB/NJ m 5.97 0.95   3 0.549 0.159 5.0, 6.9 0.56
KK/HlJ f 4.4 1.69   5 0.754 0.383 3.0, 7.2 -0.46
KK/HlJ m 4.33 0.321   3 0.186 0.0742 4.1, 4.7 -0.55
LP/J f 5.93 2.22   3 1.28 0.375 4.6, 8.5 0.96
LP/J m 4.77 0.643   3 0.371 0.135 4.3, 5.5 -0.25
MRL/MpJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.83
MRL/MpJ m 4.17 1.36   3 0.784 0.326 2.9, 5.6 -0.66
NOD.B10Sn-H2b/J f 5.47 0.751   3 0.433 0.137 4.7, 6.2 0.54
NOD.B10Sn-H2b/J m 3.4 1.27   2   0.9 0.374 2.5, 4.3 -1.18
NON/ShiLtJ f 5.87 1.34   3 0.775 0.229 4.9, 7.4 0.91
NON/ShiLtJ m 9.05 3.61   2   2.55 0.398 6.5, 11.6 2.65
NZO/HlLtJ f 6.6 3.11   2   2.2 0.471 4.4, 8.8 1.59
NZO/HlLtJ m 7.25 0.354   2   0.25 0.0488 7.0, 7.5 1.43
NZW/LacJ f 6.77 1.34   3 0.775 0.198 5.8, 8.3 1.74
NZW/LacJ m 5.97 0.503   3 0.291 0.0844 5.5, 6.5 0.56
P/J f 4.27 0.306   3 0.176 0.0716 4.0, 4.6 -0.58
P/J m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.1
PL/J f 4.9 1.51   3 0.874 0.309 3.2, 6.1 0.01
PL/J m 4.6 0.0   1   0.0 0.0 4.6, 4.6 -0.37
PWD/PhJ f 5.8 1.23   3 0.709 0.212 4.9, 7.2 0.84
PWD/PhJ m 5.42 1.26   5 0.562 0.232 4.5, 7.6 0.19
RIIIS/J f 4.2 0.735   5 0.329 0.175 3.3, 5.3 -0.64
RIIIS/J m 3.5 0.2   3 0.115 0.0571 3.3, 3.7 -1.11
SM/J f 5.47 0.611   3 0.353 0.112 4.8, 6.0 0.54
SM/J m 8.55 4.17   2   2.95 0.488 5.6, 11.5 2.31
SWR/J m 3.87 0.907   3 0.524 0.235 3.2, 4.9 -0.86
WSB/EiJ m 4.1 0.4   3 0.231 0.0976 3.7, 4.5 -0.71


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.1 0.7127 6.5146 3.6854
129S1/SvImJ m 5.1 0.7127 6.5146 3.6854
A/J f 3.86 0.552 4.9557 2.7643
A/J m 4.9 0.7127 6.3146 3.4854
BALB/cByJ f 3.86 0.552 4.9557 2.7643
BALB/cByJ m 6.92 0.552 8.0157 5.8243
BTBR T+ Itpr3tf/J f 4.5667 0.7127 5.9813 3.1521
BTBR T+ Itpr3tf/J m 5.85 0.8728 7.5825 4.1175
BUB/BnJ f 3.9 0.7127 5.3146 2.4854
BUB/BnJ m 4.2 0.8728 5.9325 2.4675
C3H/HeJ f 5.5 0.7127 6.9146 4.0854
C3H/HeJ m 4.7 0.7127 6.1146 3.2854
C57BL/10J f 6.3333 0.7127 7.7479 4.9187
C57BL/10J m 3.8667 0.7127 5.2813 2.4521
C57BL/6J f 5.1 0.7127 6.5146 3.6854
C57BL/6J m 3.7333 0.7127 5.1479 2.3187
C57BLKS/J f 2.8667 0.7127 4.2813 1.4521
C57BLKS/J m 3.9 0.7127 5.3146 2.4854
C57BR/cdJ f 3.4667 0.7127 4.8813 2.0521
C57BR/cdJ m 3.9333 0.7127 5.3479 2.5187
C57L/J f 5.1 0.7127 6.5146 3.6854
C57L/J m 6.9667 0.7127 8.3813 5.5521
CBA/J f 4.0 0.7127 5.4146 2.5854
CBA/J m 4.4 0.8728 6.1325 2.6675
DBA/2J f 6.4333 0.7127 7.8479 5.0187
DBA/2J m 5.6 0.7127 7.0146 4.1854
FVB/NJ f 3.4667 0.7127 4.8813 2.0521
FVB/NJ m 5.9667 0.7127 7.3813 4.5521
KK/HlJ f 4.4 0.552 5.4957 3.3043
KK/HlJ m 4.3333 0.7127 5.7479 2.9187
LP/J f 5.9333 0.7127 7.3479 4.5187
LP/J m 4.7667 0.7127 6.1813 3.3521
NOD.B10Sn-H2b/J f 5.4667 0.7127 6.8813 4.0521
NOD.B10Sn-H2b/J m 3.4 0.8728 5.1325 1.6675
NON/ShiLtJ f 5.8667 0.7127 7.2813 4.4521
NON/ShiLtJ m 9.05 0.8728 10.7825 7.3175
NZO/HlLtJ f 6.6 0.8728 8.3325 4.8675
NZO/HlLtJ m 7.25 0.8728 8.9825 5.5175
NZW/LacJ f 6.7667 0.7127 8.1813 5.3521
NZW/LacJ m 5.9667 0.7127 7.3813 4.5521
PWD/PhJ f 5.8 0.7127 7.2146 4.3854
PWD/PhJ m 5.42 0.552 6.5157 4.3243
RIIIS/J f 4.2 0.552 5.2957 3.1043
RIIIS/J m 3.5 0.7127 4.9146 2.0854
SM/J f 5.4667 0.7127 6.8813 4.0521
SM/J m 8.55 0.8728 10.2825 6.8175


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.1 0.5039 6.1003 4.0997
A/J both 4.38 0.4507 5.2747 3.4853
BALB/cByJ both 5.39 0.3903 6.1648 4.6152
BTBR T+ Itpr3tf/J both 5.2083 0.5634 6.3267 4.09
BUB/BnJ both 4.05 0.5634 5.1683 2.9317
C3H/HeJ both 5.1 0.5039 6.1003 4.0997
C57BL/10J both 5.1 0.5039 6.1003 4.0997
C57BL/6J both 4.4167 0.5039 5.4169 3.4164
C57BLKS/J both 3.3833 0.5039 4.3836 2.3831
C57BR/cdJ both 3.7 0.5039 4.7003 2.6997
C57L/J both 6.0333 0.5039 7.0336 5.0331
CBA/J both 4.2 0.5634 5.3183 3.0817
DBA/2J both 6.0167 0.5039 7.0169 5.0164
FVB/NJ both 4.7167 0.5039 5.7169 3.7164
KK/HlJ both 4.3667 0.4507 5.2613 3.472
LP/J both 5.35 0.5039 6.3503 4.3497
NOD.B10Sn-H2b/J both 4.4333 0.5634 5.5517 3.315
NON/ShiLtJ both 7.4583 0.5634 8.5767 6.34
NZO/HlLtJ both 6.925 0.6172 8.1501 5.6999
NZW/LacJ both 6.3667 0.5039 7.3669 5.3664
PWD/PhJ both 5.61 0.4507 6.5047 4.7153
RIIIS/J both 3.85 0.4507 4.7447 2.9553
SM/J both 7.0083 0.5634 8.1267 5.89




  GWAS USING LINEAR MIXED MODELS