Project measure / variable:   Mills1   early_apoptotic_M20

ID, description, units MPD:25207   early_apoptotic_M20   early apoptotic splenocytes   [%]  at age 20mo  
Data set, strains Mills1   inbred   28 strains     sex: both     age: 87wks
Procedure apoptosis assessment
Ontology mappings

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  STRAIN COMPARISON PLOT
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Mills1 - early apoptotic splenocytes at age 20mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains28 strains
Mean of the strain means4.87   % 3.70   %
Median of the strain means4.35   % 3.50   %
SD of the strain means± 1.95 ± 1.78
Coefficient of variation (CV)0.400 0.482
Min–max range of strain means2.10   –   8.67   % 1.45   –   9.90   %
Mean sample size per strain3.2   mice 2.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 33.0927 33.0927 8.1009 0.0054
strain 22 208.72 9.4873 2.3224 0.0027
sex:strain 22 219.6689 9.985 2.4442 0.0015
Residuals 96 392.168 4.0851


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.53 0.862   3 0.498 0.156 4.6, 6.3 0.34
129S1/SvImJ m 3.43 1.47   3 0.851 0.429 2.3, 5.1 -0.15
A/J f 4.24 0.55   5 0.246 0.13 3.5, 5.0 -0.32
A/J m 2.33 0.666   3 0.384 0.285 1.9, 3.1 -0.77
BALB/cByJ f 2.4 1.62   5 0.723 0.674 1.1, 5.2 -1.27
BALB/cByJ m 2.3 0.815   5 0.365 0.355 1.7, 3.6 -0.79
BTBR T+ Itpr3tf/J f 4.87 0.569   3 0.328 0.117 4.4, 5.5 0.0
BTBR T+ Itpr3tf/J m 4.4 0.0   2   0.0 0.0 4.4, 4.4 0.39
BUB/BnJ f 4.27 0.643   3 0.371 0.151 3.8, 5.0 -0.31
BUB/BnJ m 2.4 0.99   2   0.7 0.412 1.7, 3.1 -0.73
C3H/HeJ f 2.93 0.737   3 0.426 0.251 2.1, 3.5 -0.99
C3H/HeJ m 4.1 0.265   3 0.153 0.0645 3.8, 4.3 0.22
C57BL/10J f 5.83 2.35   3 1.36 0.404 3.4, 8.1 0.5
C57BL/10J m 3.57 0.929   3 0.536 0.261 2.5, 4.2 -0.07
C57BL/6J f 5.37 0.351   3 0.203 0.0654 5.0, 5.7 0.26
C57BL/6J m 2.23 0.404   3 0.233 0.181 1.8, 2.6 -0.83
C57BLKS/J f 2.67 0.987   3 0.57 0.37 2.0, 3.8 -1.13
C57BLKS/J m 1.8 0.361   3 0.208 0.2 1.5, 2.2 -1.07
C57BR/cdJ f 3.93 0.874   3 0.504 0.222 3.2, 4.9 -0.48
C57BR/cdJ m 4.37 2.67   3 1.54 0.61 2.4, 7.4 0.37
C57L/J f 3.23 1.63   3 0.94 0.504 2.1, 5.1 -0.84
C57L/J m 5.73 2.77   3 1.6 0.484 3.4, 8.8 1.14
CBA/J f 8.67 1.42   3 0.817 0.163 7.8, 10.3 1.95
CBA/J m 1.45 0.212   2   0.15 0.146 1.3, 1.6 -1.26
DBA/2J f 3.3 0.265   3 0.153 0.0802 3.0, 3.5 -0.8
DBA/2J m 3.73 1.08   3 0.623 0.289 2.5, 4.5 0.02
FVB/NJ f 2.1 0.436   3 0.252 0.208 1.6, 2.4 -1.42
FVB/NJ m 5.17 1.7   3 0.984 0.33 3.2, 6.2 0.82
KK/HlJ f 5.1 1.4   5 0.626 0.275 3.7, 7.2 0.12
KK/HlJ m 6.6 2.04   3 1.18 0.309 5.0, 8.9 1.63
LP/J f 7.63 5.71   3 3.3 0.748 3.8, 14.2 1.42
LP/J m 2.5 0.529   3 0.306 0.212 2.1, 3.1 -0.67
MRL/MpJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.96
MRL/MpJ m 4.8 1.97   3 1.14 0.41 2.6, 6.4 0.62
NOD.B10Sn-H2b/J f 4.43 2.57   3 1.48 0.58 1.5, 6.3 -0.22
NOD.B10Sn-H2b/J m 2.75 1.06   2   0.75 0.386 2.0, 3.5 -0.53
NON/ShiLtJ f 6.07 1.43   3 0.825 0.236 4.5, 7.3 0.62
NON/ShiLtJ m 4.95 3.46   2   2.45 0.7 2.5, 7.4 0.7
NZO/HlLtJ f 8.45 4.88   2   3.45 0.577 5.0, 11.9 1.84
NZO/HlLtJ m 4.0 1.7   2   1.2 0.424 2.8, 5.2 0.17
NZW/LacJ f 7.77 7.16   3 4.14 0.922 2.4, 15.9 1.49
NZW/LacJ m 4.43 2.23   3 1.29 0.503 3.0, 7.0 0.41
P/J f 4.27 0.208   3 0.12 0.0488 4.1, 4.5 -0.31
P/J m 4.5 0.0   1   0.0 0.0 4.5, 4.5 0.45
PL/J f 8.27 7.58   3 4.38 0.917 2.7, 16.9 1.75
PL/J m 1.9 0.0   1   0.0 0.0 1.9, 1.9 -1.01
PWD/PhJ f 4.0 1.65   3 0.95 0.412 3.0, 5.9 -0.44
PWD/PhJ m 2.68 0.719   5 0.322 0.268 1.7, 3.6 -0.57
RIIIS/J f 3.18 0.687   5 0.307 0.216 2.5, 4.2 -0.87
RIIIS/J m 3.07 0.0577   3 0.0333 0.0188 3.0, 3.1 -0.35
SM/J f 5.0 0.755   3 0.436 0.151 4.2, 5.7 0.07
SM/J m 9.9 6.36   2   4.5 0.643 5.4, 14.4 3.48
SWR/J m 2.13 0.493   3 0.285 0.231 1.8, 2.7 -0.88
WSB/EiJ m 2.43 0.351   3 0.203 0.144 2.1, 2.8 -0.71


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.5333 1.1669 7.8496 3.217
129S1/SvImJ m 3.4333 1.1669 5.7496 1.117
A/J f 4.24 0.9039 6.0342 2.4458
A/J m 2.3333 1.1669 4.6496 0.017
BALB/cByJ f 2.4 0.9039 4.1942 0.6058
BALB/cByJ m 2.3 0.9039 4.0942 0.5058
BTBR T+ Itpr3tf/J f 4.8667 1.1669 7.183 2.5504
BTBR T+ Itpr3tf/J m 4.4 1.4292 7.2369 1.5631
BUB/BnJ f 4.2667 1.1669 6.583 1.9504
BUB/BnJ m 2.4 1.4292 5.2369 0.0
C3H/HeJ f 2.9333 1.1669 5.2496 0.617
C3H/HeJ m 4.1 1.1669 6.4163 1.7837
C57BL/10J f 5.8333 1.1669 8.1496 3.517
C57BL/10J m 3.5667 1.1669 5.883 1.2504
C57BL/6J f 5.3667 1.1669 7.683 3.0504
C57BL/6J m 2.2333 1.1669 4.5496 0.0
C57BLKS/J f 2.6667 1.1669 4.983 0.3504
C57BLKS/J m 1.8 1.1669 4.1163 0.0
C57BR/cdJ f 3.9333 1.1669 6.2496 1.617
C57BR/cdJ m 4.3667 1.1669 6.683 2.0504
C57L/J f 3.2333 1.1669 5.5496 0.917
C57L/J m 5.7333 1.1669 8.0496 3.417
CBA/J f 8.6667 1.1669 10.983 6.3504
CBA/J m 1.45 1.4292 4.2869 0.0
DBA/2J f 3.3 1.1669 5.6163 0.9837
DBA/2J m 3.7333 1.1669 6.0496 1.417
FVB/NJ f 2.1 1.1669 4.4163 0.0
FVB/NJ m 5.1667 1.1669 7.483 2.8504
KK/HlJ f 5.1 0.9039 6.8942 3.3058
KK/HlJ m 6.6 1.1669 8.9163 4.2837
LP/J f 7.6333 1.1669 9.9496 5.317
LP/J m 2.5 1.1669 4.8163 0.1837
NOD.B10Sn-H2b/J f 4.4333 1.1669 6.7496 2.117
NOD.B10Sn-H2b/J m 2.75 1.4292 5.5869 0.0
NON/ShiLtJ f 6.0667 1.1669 8.383 3.7504
NON/ShiLtJ m 4.95 1.4292 7.7869 2.1131
NZO/HlLtJ f 8.45 1.4292 11.2869 5.6131
NZO/HlLtJ m 4.0 1.4292 6.8369 1.1631
NZW/LacJ f 7.7667 1.1669 10.083 5.4504
NZW/LacJ m 4.4333 1.1669 6.7496 2.117
PWD/PhJ f 4.0 1.1669 6.3163 1.6837
PWD/PhJ m 2.68 0.9039 4.4742 0.8858
RIIIS/J f 3.18 0.9039 4.9742 1.3858
RIIIS/J m 3.0667 1.1669 5.383 0.7504
SM/J f 5.0 1.1669 7.3163 2.6837
SM/J m 9.9 1.4292 12.7369 7.0631


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.4833 0.8251 6.1212 2.8455
A/J both 3.2867 0.738 4.7516 1.8217
BALB/cByJ both 2.35 0.6391 3.6187 1.0813
BTBR T+ Itpr3tf/J both 4.6333 0.9225 6.4645 2.8021
BUB/BnJ both 3.3333 0.9225 5.1645 1.5021
C3H/HeJ both 3.5167 0.8251 5.1545 1.8788
C57BL/10J both 4.7 0.8251 6.3379 3.0621
C57BL/6J both 3.8 0.8251 5.4379 2.1621
C57BLKS/J both 2.2333 0.8251 3.8712 0.5955
C57BR/cdJ both 4.15 0.8251 5.7879 2.5121
C57L/J both 4.4833 0.8251 6.1212 2.8455
CBA/J both 5.0583 0.9225 6.8895 3.2271
DBA/2J both 3.5167 0.8251 5.1545 1.8788
FVB/NJ both 3.6333 0.8251 5.2712 1.9955
KK/HlJ both 5.85 0.738 7.315 4.385
LP/J both 5.0667 0.8251 6.7045 3.4288
NOD.B10Sn-H2b/J both 3.5917 0.9225 5.4229 1.7605
NON/ShiLtJ both 5.5083 0.9225 7.3395 3.6771
NZO/HlLtJ both 6.225 1.0106 8.231 4.219
NZW/LacJ both 6.1 0.8251 7.7379 4.4621
PWD/PhJ both 3.34 0.738 4.805 1.875
RIIIS/J both 3.1233 0.738 4.5883 1.6584
SM/J both 7.45 0.9225 9.2812 5.6188




  GWAS USING LINEAR MIXED MODELS