Project measure / variable:   Mills1   early_apoptotic_M12

ID, description, units MPD:25206   early_apoptotic_M12   early apoptotic splenocytes   [%]  at age 12mo  
Data set, strains Mills1   inbred   29 strains     sex: both     age: 52wks
Procedure apoptosis assessment
Ontology mappings

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  STRAIN COMPARISON PLOT
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Mills1 - early apoptotic splenocytes at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains27 strains
Mean of the strain means3.29   % 2.38   %
Median of the strain means3.07   % 2.22   %
SD of the strain means± 1.42 ± 1.01
Coefficient of variation (CV)0.430 0.424
Min–max range of strain means1.47   –   7.73   % 1.07   –   5.63   %
Mean sample size per strain3.3   mice 3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 34.0009 34.0009 29.9066 < 0.0001
strain 23 193.9528 8.4327 7.4173 < 0.0001
sex:strain 23 43.5298 1.8926 1.6647 0.0403
Residuals 125 142.1128 1.1369


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.77 0.252   3 0.145 0.142 1.5, 2.0 -1.07
129S1/SvImJ m 3.78 0.458   6 0.187 0.121 3.2, 4.6 1.39
A/J m 2.2 0.436   3 0.252 0.198 1.7, 2.5 -0.18
AKR/J f 7.73 2.6   3 1.5 0.336 5.1, 10.3 3.14
AKR/J m 5.63 3.58   3 2.07 0.635 1.7, 8.7 3.23
BALB/cByJ f 1.47 0.153   3 0.0882 0.104 1.3, 1.6 -1.29
BALB/cByJ m 1.13 0.153   3 0.0882 0.135 1.0, 1.3 -1.24
BTBR T+ Itpr3tf/J f 3.7 1.65   3 0.954 0.447 2.6, 5.6 0.29
BTBR T+ Itpr3tf/J m 2.64 1.72   5 0.769 0.651 1.2, 5.5 0.26
BUB/BnJ f 2.98 1.02   6 0.417 0.342 1.7, 4.5 -0.22
BUB/BnJ m 2.25 0.0707   2   0.05 0.0314 2.2, 2.3 -0.13
C3H/HeJ f 2.63 0.321   3 0.186 0.122 2.4, 3.0 -0.47
C3H/HeJ m 1.5 0.141   2   0.1 0.0943 1.4, 1.6 -0.87
C57BL/10J f 3.07 1.01   6 0.413 0.33 2.3, 4.9 -0.16
C57BL/10J m 2.84 1.65   5 0.74 0.583 1.3, 4.9 0.46
C57BL/6J f 2.03 0.513   3 0.296 0.252 1.6, 2.6 -0.89
C57BL/6J m 1.67 0.153   3 0.0882 0.0917 1.5, 1.8 -0.7
C57BLKS/J f 1.82 0.386   4 0.193 0.212 1.3, 2.2 -1.04
C57BLKS/J m 1.07 0.153   3 0.0882 0.143 0.9, 1.2 -1.3
C57BR/cdJ f 2.6 0.436   3 0.252 0.168 2.1, 2.9 -0.49
C57BR/cdJ m 1.43 0.208   3 0.12 0.145 1.2, 1.6 -0.94
C57L/J f 3.53 1.31   3 0.754 0.369 2.5, 5.0 0.17
C57L/J m 2.03 0.115   3 0.0667 0.0568 1.9, 2.1 -0.34
CBA/J f 3.8 0.9   3 0.52 0.237 2.9, 4.7 0.36
CBA/J m 1.7 0.361   3 0.208 0.212 1.3, 2.0 -0.67
DBA/2J f 3.3 1.01   3 0.586 0.308 2.4, 4.4 0.01
DBA/2J m 2.47 0.509   6 0.208 0.206 1.9, 3.3 0.09
FVB/NJ f 5.5 0.458   3 0.265 0.0833 5.0, 5.9 1.56
FVB/NJ m 2.17 0.874   3 0.504 0.403 1.2, 2.9 -0.21
KK/HlJ f 4.43 0.153   3 0.0882 0.0345 4.3, 4.6 0.81
KK/HlJ m 3.97 0.404   3 0.233 0.102 3.6, 4.4 1.58
LP/J f 2.23 0.208   3 0.12 0.0932 2.0, 2.4 -0.75
LP/J m 2.32 0.708   6 0.289 0.306 1.6, 3.5 -0.06
MRL/MpJ f 2.52 0.64   4 0.32 0.253 1.7, 3.2 -0.54
MRL/MpJ m 1.64 0.288   5 0.129 0.176 1.4, 2.1 -0.73
NOD.B10Sn-H2b/J f 5.83 1.76   3 1.02 0.302 3.8, 6.9 1.79
NOD.B10Sn-H2b/J m 2.87 0.513   3 0.296 0.179 2.3, 3.3 0.49
NON/ShiLtJ f 3.87 0.814   3 0.47 0.211 3.3, 4.8 0.41
NON/ShiLtJ m 2.77 0.404   3 0.233 0.146 2.4, 3.2 0.39
NZO/HlLtJ f 3.0 0.52   3 0.3 0.173 2.7, 3.6 -0.2
NZO/HlLtJ m 3.5 0.0   1   0.0 0.0 3.5, 3.5 1.11
NZW/LacJ f 2.27 0.153   3 0.0882 0.0674 2.1, 2.4 -0.72
NZW/LacJ m 1.4 0.361   3 0.208 0.258 1.0, 1.7 -0.97
P/J m 2.53 1.29   3 0.742 0.508 1.6, 4.0 0.15
PL/J f 1.93 1.46   4 0.732 0.76 -0.96
PL/J m 1.57 0.493   3 0.285 0.315 1.0, 1.9 -0.8
PWD/PhJ f 1.87 0.987   3 0.57 0.529 1.2, 3.0 -1.0
RIIIS/J f 3.5 0.656   3 0.379 0.187 2.9, 4.2 0.15
RIIIS/J m 2.22 0.995   6 0.406 0.449 1.3, 3.7 -0.16
SJL/J f 3.83 0.723   3 0.418 0.189 3.0, 4.3 0.38
SM/J f 4.5 1.71   3 0.987 0.38 2.9, 6.3 0.85
SM/J m 3.17 1.11   3 0.639 0.349 2.0, 4.2 0.79
WSB/EiJ f 3.12 0.719   5 0.322 0.23 2.4, 4.3 -0.12
WSB/EiJ m 1.72 1.9   5 0.851 1.11 0.6, 5.1 -0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.7667 0.6156 2.985 0.5483
129S1/SvImJ m 3.7833 0.4353 4.6448 2.9218
AKR/J f 7.7333 0.6156 8.9517 6.515
AKR/J m 5.6333 0.6156 6.8517 4.415
BALB/cByJ f 1.4667 0.6156 2.685 0.2483
BALB/cByJ m 1.1333 0.6156 2.3517 0.0
BTBR T+ Itpr3tf/J f 3.7 0.6156 4.9184 2.4816
BTBR T+ Itpr3tf/J m 2.64 0.4768 3.5837 1.6963
BUB/BnJ f 2.9833 0.4353 3.8448 2.1218
BUB/BnJ m 2.25 0.754 3.7422 0.7578
C3H/HeJ f 2.6333 0.6156 3.8517 1.415
C3H/HeJ m 1.5 0.754 2.9922 0.0078
C57BL/10J f 3.0667 0.4353 3.9282 2.2052
C57BL/10J m 2.84 0.4768 3.7837 1.8963
C57BL/6J f 2.0333 0.6156 3.2517 0.815
C57BL/6J m 1.6667 0.6156 2.885 0.4483
C57BLKS/J f 1.825 0.5331 2.8801 0.7699
C57BLKS/J m 1.0667 0.6156 2.285 0.0
C57BR/cdJ f 2.6 0.6156 3.8184 1.3816
C57BR/cdJ m 1.4333 0.6156 2.6517 0.215
C57L/J f 3.5333 0.6156 4.7517 2.315
C57L/J m 2.0333 0.6156 3.2517 0.815
CBA/J f 3.8 0.6156 5.0184 2.5816
CBA/J m 1.7 0.6156 2.9184 0.4816
DBA/2J f 3.3 0.6156 4.5184 2.0816
DBA/2J m 2.4667 0.4353 3.3282 1.6052
FVB/NJ f 5.5 0.6156 6.7184 4.2816
FVB/NJ m 2.1667 0.6156 3.385 0.9483
KK/HlJ f 4.4333 0.6156 5.6517 3.215
KK/HlJ m 3.9667 0.6156 5.185 2.7483
LP/J f 2.2333 0.6156 3.4517 1.015
LP/J m 2.3167 0.4353 3.1782 1.4552
MRL/MpJ f 2.525 0.5331 3.5801 1.4699
MRL/MpJ m 1.64 0.4768 2.5837 0.6963
NOD.B10Sn-H2b/J f 5.8333 0.6156 7.0517 4.615
NOD.B10Sn-H2b/J m 2.8667 0.6156 4.085 1.6483
NON/ShiLtJ f 3.8667 0.6156 5.085 2.6483
NON/ShiLtJ m 2.7667 0.6156 3.985 1.5483
NZW/LacJ f 2.2667 0.6156 3.485 1.0483
NZW/LacJ m 1.4 0.6156 2.6184 0.1816
PL/J f 1.925 0.5331 2.9801 0.8699
PL/J m 1.5667 0.6156 2.785 0.3483
RIIIS/J f 3.5 0.6156 4.7184 2.2816
RIIIS/J m 2.2167 0.4353 3.0782 1.3552
SM/J f 4.5 0.6156 5.7184 3.2816
SM/J m 3.1667 0.6156 4.385 1.9483
WSB/EiJ f 3.12 0.4768 4.0637 2.1763
WSB/EiJ m 1.72 0.4768 2.6637 0.7763


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.775 0.377 3.5211 2.0289
AKR/J both 6.6833 0.4353 7.5448 5.8218
BALB/cByJ both 1.3 0.4353 2.1615 0.4385
BTBR T+ Itpr3tf/J both 3.17 0.3893 3.9406 2.3994
BUB/BnJ both 2.6167 0.4353 3.4782 1.7552
C3H/HeJ both 2.0667 0.4867 3.0299 1.1035
C57BL/10J both 2.9533 0.3228 3.5922 2.3144
C57BL/6J both 1.85 0.4353 2.7115 0.9885
C57BLKS/J both 1.4458 0.4072 2.2517 0.64
C57BR/cdJ both 2.0167 0.4353 2.8782 1.1552
C57L/J both 2.7833 0.4353 3.6448 1.9218
CBA/J both 2.75 0.4353 3.6115 1.8885
DBA/2J both 2.8833 0.377 3.6294 2.1372
FVB/NJ both 3.8333 0.4353 4.6948 2.9718
KK/HlJ both 4.2 0.4353 5.0615 3.3385
LP/J both 2.275 0.377 3.0211 1.5289
MRL/MpJ both 2.0825 0.3576 2.7903 1.3747
NOD.B10Sn-H2b/J both 4.35 0.4353 5.2115 3.4885
NON/ShiLtJ both 3.3167 0.4353 4.1782 2.4552
NZW/LacJ both 1.8333 0.4353 2.6948 0.9718
PL/J both 1.7458 0.4072 2.5517 0.94
RIIIS/J both 2.8583 0.377 3.6044 2.1122
SM/J both 3.8333 0.4353 4.6948 2.9718
WSB/EiJ both 2.42 0.3372 3.0873 1.7527




  GWAS USING LINEAR MIXED MODELS