Project measure / variable:   Seburn2   grip_strength_M12

ID, description, units MPD:24802   grip_strength_M12   grip strength, peak tension over 3 trials   [g]  at age 12mo  
Data set, strains Seburn2   inbred   30 strains     sex: both     age: 52wks
Procedure grip strength
Ontology mappings

  STRAIN COMPARISON PLOT
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Seburn2 - grip strength, peak tension over 3 trials at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means106   g 114   g
Median of the strain means105   g 112   g
SD of the strain means± 15.1 ± 16.9
Coefficient of variation (CV)0.142 0.148
Min–max range of strain means77.0   –   144   g 70.2   –   158   g
Mean sample size per strain7.6   mice 7.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9629.0817 9629.0817 71.7673 < 0.0001
strain 29 86191.995 2972.1378 22.1519 < 0.0001
sex:strain 29 20805.8483 717.443 5.3472 < 0.0001
Residuals 389 52192.5062 134.171


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 120.0 8.75   8 3.09 0.0729 106.0, 133.0 0.93
129S1/SvImJ m 122.0 16.9   8 5.96 0.138 92.7, 143.0 0.49
A/J f 104.0 10.3   8 3.64 0.0995 91.7, 116.0 -0.13
A/J m 123.0 11.9   8 4.22 0.097 98.0, 136.0 0.55
BALB/cByJ f 139.0 7.21   8 2.55 0.0519 128.0, 151.0 2.19
BALB/cByJ m 152.0 5.58   8 1.97 0.0366 147.0, 162.0 2.27
BTBR T+ Itpr3tf/J f 118.0 12.5   8 4.42 0.106 96.7, 135.0 0.8
BTBR T+ Itpr3tf/J m 109.0 11.2   6 4.58 0.103 96.0, 128.0 -0.28
BUB/BnJ f 99.4 17.5   6 7.16 0.177 72.7, 125.0 -0.43
BUB/BnJ m 131.0 12.4   8 4.4 0.0951 105.0, 148.0 1.03
C3H/HeJ f 110.0 12.0   8 4.26 0.109 87.0, 127.0 0.27
C3H/HeJ m 120.0 17.1   8 6.04 0.142 96.7, 149.0 0.38
C57BL/10J f 95.9 11.7   8 4.12 0.122 78.7, 120.0 -0.66
C57BL/10J m 104.0 7.26   8 2.57 0.07 91.3, 112.0 -0.57
C57BL/6J f 103.0 6.24   8 2.21 0.0604 94.3, 111.0 -0.19
C57BL/6J m 104.0 9.39   8 3.32 0.0905 90.3, 115.0 -0.57
C57BLKS/J f 108.0 7.91   8 2.8 0.0734 95.0, 119.0 0.14
C57BLKS/J m 96.0 5.43   6 2.22 0.0566 86.3, 102.0 -1.05
C57BR/cdJ f 109.0 9.29   6 3.79 0.0848 96.7, 123.0 0.21
C57BR/cdJ m 117.0 8.85   8 3.13 0.0756 110.0, 131.0 0.2
C57L/J f 93.8 7.64   8 2.7 0.0815 85.7, 110.0 -0.8
C57L/J m 110.0 7.05   8 2.49 0.0642 100.0, 122.0 -0.22
CAST/EiJ f 86.0 15.0   11 4.53 0.175 67.7, 106.0 -1.32
CAST/EiJ m 70.2 7.57   3 4.37 0.108 63.3, 78.3 -2.58
CBA/J f 110.0 8.77   7 3.32 0.0796 98.3, 121.0 0.27
CBA/J m 116.0 5.05   7 1.91 0.0436 108.0, 123.0 0.14
DBA/2J f 97.3 2.18   6 0.89 0.0224 94.3, 100.0 -0.57
DBA/2J m 109.0 13.7   7 5.17 0.126 90.3, 130.0 -0.28
FVB/NJ f 93.0 9.03   8 3.19 0.097 77.7, 107.0 -0.85
FVB/NJ m 108.0 12.4   7 4.68 0.115 92.3, 129.0 -0.34
KK/HlJ f 106.0 9.41   8 3.33 0.0887 88.7, 121.0 0.01
KK/HlJ m 94.6 5.9   8 2.09 0.0624 83.0, 104.0 -1.13
LP/J f 116.0 5.09   6 2.08 0.044 111.0, 122.0 0.67
LP/J m 108.0 8.15   8 2.88 0.0757 92.7, 117.0 -0.34
MRL/MpJ f 109.0 25.7   6 10.5 0.235 76.3, 137.0 0.21
MRL/MpJ m 158.0 13.5   8 4.76 0.0855 137.0, 174.0 2.63
NOD.B10Sn-H2b/J f 144.0 8.45   8 2.99 0.0589 132.0, 153.0 2.53
NOD.B10Sn-H2b/J m 135.0 12.3   7 4.67 0.0914 121.0, 155.0 1.27
NON/ShiLtJ f 88.9 31.1   8 11.0 0.35 38.0, 124.0 -1.13
NON/ShiLtJ m 120.0 8.83   8 3.12 0.0734 106.0, 131.0 0.38
NZO/HlLtJ f 111.0 5.18   8 1.83 0.0467 103.0, 118.0 0.34
NZO/HlLtJ m 105.0 12.2   7 4.61 0.116 92.0, 124.0 -0.51
NZW/LacJ f 125.0 20.7   8 7.3 0.166 75.3, 138.0 1.27
NZW/LacJ m 119.0 10.8   7 4.08 0.0907 99.3, 130.0 0.32
P/J f 124.0 4.39   7 1.66 0.0355 119.0, 132.0 1.2
P/J m 127.0 19.0   8 6.71 0.149 106.0, 158.0 0.79
PL/J f 90.5 7.6   8 2.69 0.084 78.3, 100.0 -1.02
PL/J m 107.0 5.5   7 2.08 0.0514 98.7, 114.0 -0.4
PWD/PhJ f 77.0 8.13   8 2.87 0.106 62.3, 87.3 -1.92
PWD/PhJ m 94.6 13.7   8 4.86 0.145 70.3, 113.0 -1.13
RIIIS/J f 113.0 9.84   8 3.48 0.0874 101.0, 134.0 0.47
RIIIS/J m 114.0 4.49   8 1.59 0.0393 106.0, 121.0 0.02
SJL/J f 86.9 13.3   7 5.01 0.153 68.0, 104.0 -1.26
SJL/J m 98.5 9.91   7 3.75 0.101 82.3, 112.0 -0.9
SM/J f 99.5 5.44   8 1.92 0.0547 92.3, 107.0 -0.42
SM/J m 112.0 7.0   8 2.47 0.0626 100.0, 123.0 -0.1
SWR/J f 97.8 8.88   8 3.14 0.0909 83.7, 108.0 -0.54
SWR/J m 113.0 11.7   6 4.79 0.103 103.0, 134.0 -0.04
WSB/EiJ f 102.0 8.19   7 3.1 0.0801 91.3, 118.0 -0.26
WSB/EiJ m 113.0 9.88   7 3.73 0.0878 99.0, 121.0 -0.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 120.0 4.0953 128.0517 111.9483
129S1/SvImJ m 122.0875 4.0953 130.1392 114.0358
A/J f 103.5875 4.0953 111.6392 95.5358
A/J m 123.0 4.0953 131.0517 114.9483
BALB/cByJ f 139.0 4.0953 147.0517 130.9483
BALB/cByJ m 152.375 4.0953 160.4267 144.3233
BTBR T+ Itpr3tf/J f 117.8375 4.0953 125.8892 109.7858
BTBR T+ Itpr3tf/J m 109.0 4.7288 118.2973 99.7027
BUB/BnJ f 99.4 4.7288 108.6973 90.1027
BUB/BnJ m 130.875 4.0953 138.9267 122.8233
C3H/HeJ f 110.25 4.0953 118.3017 102.1983
C3H/HeJ m 119.9625 4.0953 128.0142 111.9108
C57BL/10J f 95.8875 4.0953 103.9392 87.8358
C57BL/10J m 103.7 4.0953 111.7517 95.6483
C57BL/6J f 103.375 4.0953 111.4267 95.3233
C57BL/6J m 103.75 4.0953 111.8017 95.6983
C57BLKS/J f 107.75 4.0953 115.8017 99.6983
C57BLKS/J m 95.95 4.7288 105.2473 86.6527
C57BR/cdJ f 109.45 4.7288 118.7473 100.1527
C57BR/cdJ m 117.0 4.0953 125.0517 108.9483
C57L/J f 93.8375 4.0953 101.8892 85.7858
C57L/J m 109.75 4.0953 117.8017 101.6983
CAST/EiJ f 85.9727 3.4925 92.8392 79.1062
CAST/EiJ m 70.2 6.6876 83.3483 57.0517
CBA/J f 110.1857 4.378 118.7933 101.5781
CBA/J m 115.8571 4.378 124.4647 107.2496
DBA/2J f 97.2833 4.7288 106.5806 87.9861
DBA/2J m 108.5143 4.378 117.1219 99.9067
FVB/NJ f 93.0125 4.0953 101.0642 84.9608
FVB/NJ m 107.6571 4.378 116.2647 99.0496
KK/HlJ f 106.0875 4.0953 114.1392 98.0358
KK/HlJ m 94.625 4.0953 102.6767 86.5733
LP/J f 115.6667 4.7288 124.9639 106.3694
LP/J m 107.5875 4.0953 115.6392 99.5358
MRL/MpJ f 109.2667 4.7288 118.5639 99.9694
MRL/MpJ m 157.5 4.0953 165.5517 149.4483
NOD.B10Sn-H2b/J f 143.5 4.0953 151.5517 135.4483
NOD.B10Sn-H2b/J m 135.1429 4.378 143.7504 126.5353
NON/ShiLtJ f 88.95 4.0953 97.0017 80.8983
NON/ShiLtJ m 120.375 4.0953 128.4267 112.3233
NZO/HlLtJ f 111.0 4.0953 119.0517 102.9483
NZO/HlLtJ m 105.3286 4.378 113.9362 96.721
NZW/LacJ f 124.7875 4.0953 132.8392 116.7358
NZW/LacJ m 119.0429 4.378 127.6504 110.4353
P/J f 123.7143 4.378 132.3219 115.1067
P/J m 127.125 4.0953 135.1767 119.0733
PL/J f 90.5125 4.0953 98.5642 82.4608
PL/J m 107.1 4.378 115.7076 98.4924
PWD/PhJ f 76.9875 4.0953 85.0392 68.9358
PWD/PhJ m 94.5875 4.0953 102.6392 86.5358
RIIIS/J f 112.625 4.0953 120.6767 104.5733
RIIIS/J m 114.125 4.0953 122.1767 106.0733
SJL/J f 86.9 4.378 95.5076 78.2924
SJL/J m 98.4857 4.378 107.0933 89.8781
SM/J f 99.45 4.0953 107.5017 91.3983
SM/J m 111.875 4.0953 119.9267 103.8233
SWR/J f 97.7625 4.0953 105.8142 89.7108
SWR/J m 113.3333 4.7288 122.6306 104.0361
WSB/EiJ f 102.2429 4.378 110.8504 93.6353
WSB/EiJ m 112.5714 4.378 121.179 103.9638


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 121.0438 2.8958 126.7371 115.3504
A/J both 113.2938 2.8958 118.9871 107.6004
BALB/cByJ both 145.6875 2.8958 151.3809 139.9941
BTBR T+ Itpr3tf/J both 113.4188 3.1278 119.5683 107.2692
BUB/BnJ both 115.1375 3.1278 121.2871 108.9879
C3H/HeJ both 115.1063 2.8958 120.7996 109.4129
C57BL/10J both 99.7938 2.8958 105.4871 94.1004
C57BL/6J both 103.5625 2.8958 109.2559 97.8691
C57BLKS/J both 101.85 3.1278 107.9996 95.7004
C57BR/cdJ both 113.225 3.1278 119.3746 107.0754
C57L/J both 101.7938 2.8958 107.4871 96.1004
CAST/EiJ both 78.0864 3.7723 85.503 70.6697
CBA/J both 113.0214 3.0957 119.1079 106.9349
DBA/2J both 102.8988 3.2222 109.2338 96.5638
FVB/NJ both 100.3348 2.9974 106.228 94.4416
KK/HlJ both 100.3563 2.8958 106.0496 94.6629
LP/J both 111.6271 3.1278 117.7766 105.4775
MRL/MpJ both 133.3833 3.1278 139.5329 127.2338
NOD.B10Sn-H2b/J both 139.3214 2.9974 145.2146 133.4282
NON/ShiLtJ both 104.6625 2.8958 110.3559 98.9691
NZO/HlLtJ both 108.1643 2.9974 114.0575 102.2711
NZW/LacJ both 121.9152 2.9974 127.8084 116.022
P/J both 125.4196 2.9974 131.3129 119.5264
PL/J both 98.8063 2.9974 104.6995 92.913
PWD/PhJ both 85.7875 2.8958 91.4809 80.0941
RIIIS/J both 113.375 2.8958 119.0684 107.6816
SJL/J both 92.6929 3.0957 98.7793 86.6064
SM/J both 105.6625 2.8958 111.3559 99.9691
SWR/J both 105.5479 3.1278 111.6975 99.3984
WSB/EiJ both 107.4071 3.0957 113.4936 101.3207




  GWAS USING LINEAR MIXED MODELS