Project measure / variable:   Peters4   MCV_M18

ID, description, units MPD:24375   MCV_M18   mean RBC corpuscular volume (MCV)   [fL]  at age 18mo  
Data set, strains Peters4   inbred   30 strains     sex: both     age: 78wks
Procedure complete blood count
Ontology mappings

  STRAIN COMPARISON PLOT
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Peters4 - mean RBC corpuscular volume (MCV) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains29 strains
Mean of the strain means46.0   fL 45.1   fL
Median of the strain means45.9   fL 45.2   fL
SD of the strain means± 2.71 ± 2.28
Coefficient of variation (CV)0.0590 0.0505
Min–max range of strain means39.4   –   52.1   fL 39.4   –   51.0   fL
Mean sample size per strain6.9   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 102.7118 102.7118 27.3116 < 0.0001
strain 26 2015.324 77.5125 20.611 < 0.0001
sex:strain 26 250.5946 9.6383 2.5629 0.0001
Residuals 331 1244.8051 3.7607


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 45.1 1.54   8 0.543 0.0341 41.8, 46.8 -0.34
129S1/SvImJ m 42.8 0.868   7 0.328 0.0203 41.5, 43.9 -1.02
A/J f 43.2 1.57   7 0.592 0.0363 39.7, 44.5 -1.04
A/J m 43.5 1.38   14 0.368 0.0316 40.1, 46.0 -0.71
BALB/cByJ f 43.5 0.958   8 0.339 0.022 42.2, 44.6 -0.93
BALB/cByJ m 42.2 1.79   7 0.676 0.0424 40.0, 44.5 -1.28
BTBR T+ Itpr3tf/J f 48.2 4.62   8 1.63 0.0958 44.4, 57.0 0.81
BTBR T+ Itpr3tf/J m 45.9 0.709   5 0.317 0.0154 44.7, 46.5 0.34
BUB/BnJ f 45.9 0.961   5 0.43 0.0209 44.9, 47.5 -0.04
BUB/BnJ m 46.4 1.16   6 0.474 0.025 44.5, 47.6 0.56
C3H/HeJ f 46.1 1.16   7 0.437 0.0251 43.7, 47.4 0.03
C3H/HeJ m 46.0 2.17   8 0.767 0.0471 41.0, 47.8 0.39
C57BL/10J f 42.5 1.66   6 0.676 0.039 40.7, 45.6 -1.3
C57BL/10J m 44.5 0.825   13 0.229 0.0185 43.0, 45.8 -0.27
C57BL/6J f 45.9 2.02   7 0.764 0.044 44.6, 50.2 -0.04
C57BL/6J m 45.5 0.663   7 0.25 0.0146 44.4, 46.3 0.17
C57BLKS/J m 43.6 0.92   16 0.23 0.0211 42.2, 45.7 -0.67
C57BR/cdJ f 47.8 3.45   7 1.3 0.0722 45.5, 55.4 0.66
C57BR/cdJ m 44.1 5.6   8 1.98 0.127 34.1, 48.0 -0.45
C57L/J f 48.3 0.725   7 0.274 0.015 47.3, 49.4 0.84
C57L/J m 48.2 2.01   7 0.761 0.0417 46.2, 51.7 1.35
CAST/EiJ f 42.6 2.27   8 0.804 0.0534 39.2, 46.0 -1.26
CBA/J f 47.5 0.707   2   0.5 0.0149 47.0, 48.0 0.55
CBA/J m 44.4 0.705   5 0.315 0.0159 43.7, 45.5 -0.31
DBA/2J f 39.4 1.01   6 0.412 0.0256 38.3, 40.8 -2.44
DBA/2J m 39.4 1.22   6 0.496 0.0309 38.1, 41.3 -2.51
FVB/NJ f 44.2 1.13   7 0.429 0.0257 42.8, 45.4 -0.67
FVB/NJ m 45.2 1.12   12 0.325 0.0249 43.7, 47.6 0.04
KK/HlJ f 48.6 2.35   6 0.961 0.0485 43.9, 50.5 0.95
KK/HlJ m 45.1 1.76   7 0.665 0.039 41.5, 47.3 -0.01
LP/J m 45.7 0.783   8 0.277 0.0171 44.7, 46.9 0.26
MRL/MpJ f 44.3 0.763   7 0.289 0.0173 42.9, 44.9 -0.63
MRL/MpJ m 44.2 1.31   8 0.463 0.0296 42.4, 46.0 -0.4
NOD.B10Sn-H2b/J f 51.2 1.95   7 0.737 0.0381 49.6, 55.4 1.91
NOD.B10Sn-H2b/J m 48.8 1.7   7 0.644 0.035 46.6, 51.8 1.62
NON/ShiLtJ f 45.1 1.15   5 0.512 0.0254 43.7, 46.8 -0.34
NON/ShiLtJ m 46.0 2.53   7 0.956 0.055 41.9, 49.0 0.39
NZO/HlLtJ f 45.2 1.34   10 0.424 0.0297 42.9, 47.2 -0.3
NZO/HlLtJ m 44.5 0.354   2   0.25 0.00794 44.3, 44.8 -0.27
NZW/LacJ f 48.5 1.59   7 0.599 0.0327 46.1, 50.1 0.92
NZW/LacJ m 45.4 0.605   6 0.247 0.0133 44.5, 46.0 0.12
P/J f 45.5 1.21   7 0.456 0.0265 43.3, 47.0 -0.19
P/J m 47.1 5.5   5 2.46 0.117 39.9, 53.9 0.87
PL/J f 45.7 1.53   8 0.539 0.0334 43.9, 48.5 -0.12
PL/J m 43.7 2.45   8 0.867 0.0561 40.9, 48.1 -0.62
PWD/PhJ f 46.1 1.04   6 0.425 0.0226 45.1, 48.1 0.03
PWD/PhJ m 42.0 1.82   7 0.688 0.0433 39.7, 43.6 -1.37
RIIIS/J f 47.6 1.14   8 0.401 0.0238 46.1, 49.6 0.58
RIIIS/J m 45.9 0.741   8 0.262 0.0161 44.7, 47.2 0.34
SJL/J f 46.7 2.75   7 1.04 0.0588 43.1, 49.9 0.25
SJL/J m 47.5 2.01   4 1.0 0.0423 45.0, 49.7 1.05
SM/J f 48.3 1.03   6 0.422 0.0214 46.8, 49.8 0.84
SM/J m 46.7 2.12   10 0.67 0.0454 41.9, 49.2 0.69
SWR/J f 52.1 2.14   7 0.809 0.0411 49.7, 55.1 2.24
SWR/J m 51.0 0.595   8 0.21 0.0117 50.0, 51.7 2.58
WSB/EiJ f 43.3 1.03   8 0.364 0.0238 42.1, 45.4 -1.0
WSB/EiJ m 43.1 0.871   9 0.29 0.0202 41.6, 44.0 -0.89


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 45.1 0.6856 46.4487 43.7513
129S1/SvImJ m 42.8429 0.733 44.2847 41.401
A/J f 43.1571 0.733 44.599 41.7153
A/J m 43.5071 0.5183 44.5267 42.4876
BALB/cByJ f 43.5 0.6856 44.8487 42.1513
BALB/cByJ m 42.1857 0.733 43.6276 40.7438
BTBR T+ Itpr3tf/J f 48.2 0.6856 49.5487 46.8513
BTBR T+ Itpr3tf/J m 45.88 0.8673 47.586 44.174
BUB/BnJ f 45.94 0.8673 47.646 44.234
BUB/BnJ m 46.4333 0.7917 47.9907 44.8759
C3H/HeJ f 46.0714 0.733 47.5133 44.6296
C3H/HeJ m 46.0375 0.6856 47.3862 44.6888
C57BL/10J f 42.4667 0.7917 44.0241 40.9093
C57BL/10J m 44.5462 0.5379 45.6042 43.4881
C57BL/6J f 45.9143 0.733 47.3562 44.4724
C57BL/6J m 45.4714 0.733 46.9133 44.0296
C57BR/cdJ f 47.7857 0.733 49.2276 46.3438
C57BR/cdJ m 44.0625 0.6856 45.4112 42.7138
C57L/J f 48.3429 0.733 49.7847 46.901
C57L/J m 48.2429 0.733 49.6847 46.801
CBA/J f 47.5 1.3713 50.1975 44.8025
CBA/J m 44.38 0.8673 46.086 42.674
DBA/2J f 39.4 0.7917 40.9574 37.8426
DBA/2J m 39.35 0.7917 40.9074 37.7926
FVB/NJ f 44.1857 0.733 45.6276 42.7438
FVB/NJ m 45.15 0.5598 46.2512 44.0488
KK/HlJ f 48.5667 0.7917 50.1241 47.0093
KK/HlJ m 45.1429 0.733 46.5847 43.701
MRL/MpJ f 44.2571 0.733 45.699 42.8153
MRL/MpJ m 44.2375 0.6856 45.5862 42.8888
NOD.B10Sn-H2b/J f 51.2 0.733 52.6419 49.7581
NOD.B10Sn-H2b/J m 48.7571 0.733 50.199 47.3153
NON/ShiLtJ f 45.06 0.8673 46.766 43.354
NON/ShiLtJ m 46.0286 0.733 47.4704 44.5867
NZO/HlLtJ f 45.17 0.6132 46.3764 43.9636
NZO/HlLtJ m 44.55 1.3713 47.2475 41.8525
NZW/LacJ f 48.5429 0.733 49.9847 47.101
NZW/LacJ m 45.4167 0.7917 46.9741 43.8593
P/J f 45.4857 0.733 46.9276 44.0438
P/J m 47.06 0.8673 48.766 45.354
PL/J f 45.7125 0.6856 47.0612 44.3638
PL/J m 43.7 0.6856 45.0487 42.3513
PWD/PhJ f 46.1 0.7917 47.6574 44.5426
PWD/PhJ m 42.0 0.733 43.4419 40.5581
RIIIS/J f 47.6375 0.6856 48.9862 46.2888
RIIIS/J m 45.8625 0.6856 47.2112 44.5138
SJL/J f 46.7429 0.733 48.1847 45.301
SJL/J m 47.475 0.9696 49.3824 45.5676
SM/J f 48.3333 0.7917 49.8907 46.7759
SM/J m 46.69 0.6132 47.8964 45.4836
SWR/J f 52.0714 0.733 53.5133 50.6296
SWR/J m 50.975 0.6856 52.3237 49.6263
WSB/EiJ f 43.325 0.6856 44.6737 41.9763
WSB/EiJ m 43.0778 0.6464 44.3494 41.8062


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 43.9714 0.5018 44.9586 42.9842
A/J both 43.3321 0.4489 44.2151 42.4492
BALB/cByJ both 42.8429 0.5018 43.83 41.8557
BTBR T+ Itpr3tf/J both 47.04 0.5528 48.1274 45.9526
BUB/BnJ both 46.1867 0.5871 47.3417 45.0317
C3H/HeJ both 46.0545 0.5018 47.0416 45.0673
C57BL/10J both 43.5064 0.4786 44.4478 42.565
C57BL/6J both 45.6929 0.5183 46.7124 44.6733
C57BR/cdJ both 45.9241 0.5018 46.9113 44.9369
C57L/J both 48.2929 0.5183 49.3124 47.2733
CBA/J both 45.94 0.8113 47.5359 44.3441
DBA/2J both 39.375 0.5598 40.4762 38.2738
FVB/NJ both 44.6679 0.4612 45.575 43.7607
KK/HlJ both 46.8548 0.5395 47.916 45.7936
MRL/MpJ both 44.2473 0.5018 45.2345 43.2601
NOD.B10Sn-H2b/J both 49.9786 0.5183 50.9981 48.959
NON/ShiLtJ both 45.5443 0.5678 46.6612 44.4274
NZO/HlLtJ both 44.86 0.7511 46.3375 43.3825
NZW/LacJ both 46.9798 0.5395 48.041 45.9186
P/J both 46.2729 0.5678 47.3897 45.156
PL/J both 44.7062 0.4848 45.66 43.7525
PWD/PhJ both 44.05 0.5395 45.1112 42.9888
RIIIS/J both 46.75 0.4848 47.7037 45.7963
SJL/J both 47.1089 0.6077 48.3045 45.9134
SM/J both 47.5117 0.5007 48.4967 46.5267
SWR/J both 51.5232 0.5018 52.5104 50.536
WSB/EiJ both 43.2014 0.4712 44.1282 42.2746




  GWAS USING LINEAR MIXED MODELS